Download or read book Characterization of Micro and Nanoparticles for Biomedical Applications written by Ranjita Shegokar and published by Elsevier. This book was released on 2023-08-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Any generic or innovative pharmaceutical product requires to undergo an extensive characterization cycle (in-vitro, ex-vivo, cell lines based evaluation) before getting to preclinical and clinical stages and eventually to be "eligible" for marketing authorization. The expectation of "high-quality data" is essentially dependent on the analytical methodology applied for characterization. For routine products like tablets, capsules, and solutions, the regulatory guidelines, product-specific monographs, and pharmacopoeial annexures are set and are "standard of operation." In addition, GMP/ISO guidelines support industries, academicians, and contract labs to evaluate, document, and validate the routine product to get qualified. However, for nano-micro pharmaceuticals, the regulatory guidelines are still evolving and are very much dependent on the literature data and "latest draft" reports from experts and regulatory body discussions. This book aims to provide one-stop resources on all the analytical techniques used in the field of micro and nanoparticles evaluation and characterization. The chapters will bring together knowledge on current analytical methodologies, limitations, and advances in the in vitro analysis field. Characterization of Micro and Nanoparticles for Biomedical Applications is a helping guide for industry researchers, academicians, regulatory experts, and material scientists working in this field of pharmaceuticals, cosmeceuticals, nutraceuticals, agriculture, food, fragrance, and chemical industry. The equipment industry can benefit from its innovations by understanding the needs of researchers and the challenges of current techniques. Covers the entire landscape of in vitro analytical techniques applied for characterization and analysis of micro-and nanoparticles in biomedicine Examines limitations and challenges of currently used methodologies Discusses new advances in the field of micro-nano characterization

Download or read book Silver Micro Nanoparticles written by Samir Kumar and published by BoD – Books on Demand. This book was released on 2021-09-15 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the different methodologies for producing and synthesizing silver nanoparticles (AgNPs) of various shapes and sizes. It also provides an in-depth understanding of the new methods for characterizing and modifying the properties of AgNPs as well as their properties and applications in various fields. This book is a useful resource for a wide range of readers, including scientists, engineers, doctoral and postdoctoral fellows, and scientific professionals working in specialized fields such as medicine, nanotechnology, spectroscopy, analytical chemistry diagnostics, and plasmonics.

Download or read book Fabrication Characterization and Biomedical Applications of Micro and Bionanoconjugates written by Vishala Santosha Ramyah Aaryasomayajula and published by . This book was released on 2013 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis includes the synthesis, conjugation and applications of nano and microparticles for the detection and diagnosis of clinically important units such as cell lysates or proteins. Chapter one presents details of the synthesis and characterization of aptamer-AuNP conjugates for the detection of proteins based on dynamic light scattering. Additions of proteins to aptamer-conjugated gold nanoparticles (AuNPs) induced the formation of dimers, trimers, oligomers or aggregates. The average hydrodynamic diameter of the aggregates as measured by DLS, increased with the corresponding increase in protein concentration. This correlation formed the analytical basis of the assay. A linear dynamic range of up to 300 nM (1800 nm) and Limit of detection of 2.67nM was realized using thrombin as the model analyte. This thesis also discusses a novel surface-based method to detect cancer cell membrane using lateral flow technology. This is conceptualized based on familiar streptavidin-biotin and lectin-glycan interactions. Here the detection of cancer cells membranes is based on a differential expression of sialic acids on cancerous cells as compared to the normal cells. The lateral flow biosensor constructed was able to corroborate successful detection cancer cell membranes in less than 40 minutes, qualitatively.

Download or read book Nanoparticles for Biomedical Applications written by Eun Ji Chung and published by Elsevier. This book was released on 2019-11-19 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications brings into one place information on the design and biomedical applications of different classes of nanoparticles. While aspects are dealt with in individual journal articles, there is not one source that covers this area comprehensively. This book fills this gap in the literature. - Outlines an in-depth review of biomedical applications of a variety of nanoparticle classes - Discusses the major techniques for designing nanoparticles for use in biomedicine - Explores safety and regulatory aspects for the use of nanoparticles in biomedicine

Download or read book Characterization of Nanoparticles written by Vasile-Dan Hodoroaba and published by Elsevier. This book was released on 2019-10-05 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterization of Nanoparticles: Measurement Processes for Nanoparticles surveys this fast growing field, including established methods for the physical and chemical characterization of nanoparticles. The book focuses on sample preparation issues (including potential pitfalls), with measurement procedures described in detail. In addition, the book explores data reduction, including the quantitative evaluation of the final result and its uncertainty of measurement. The results of published inter-laboratory comparisons are referred to, along with the availability of reference materials necessary for instrument calibration and method validation. The application of these methods are illustrated with practical examples on what is routine and what remains a challenge. In addition, this book summarizes promising methods still under development and analyzes the need for complementary methods to enhance the quality of nanoparticle characterization with solutions already in operation. - Helps readers decide which nanocharacterization method is best for each measurement problem, including limitations, advantages and disadvantages - Shows which nanocharacterization methods are best for different classes of nanomaterial - Demonstrates the practical use of a method based on selected case studies

Download or read book Green Synthesis Characterization and Applications of Nanoparticles written by Ashutosh Kumar Shukla and published by Elsevier. This book was released on 2018-11-26 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Green Synthesis, Characterization and Applications of Nanoparticles shows how eco-friendly nanoparticles are engineered and used. In particular, metal nanoparticles, metal oxide nanoparticles and other categories of nanoparticles are discussed. The book outlines a range of methodologies and explores the appropriate use of each. Characterization methods include spectroscopic, microscopic and diffraction methods, but magnetic resonance methods are also included as they can be used to understand the mechanism of nanoparticle synthesis using organisms. Applications covered include targeted drug delivery, water purification and hydrogen generation. This is an important research resource for those wishing to learn more about how eco-efficient nanoparticles can best be used. Theoretical details and mathematical derivations are kept to a necessary minimum to suit the need of interdisciplinary audiences and those who may be relatively new to the field. - Explores recent trends in growth, characterization, properties and applications of nanoparticles - Gives readers an understanding on how they are applied through the use of case studies and examples - Assesses the advantages and disadvantages of a variety of synthesis and characterization techniques for green nanoparticles in different situations

Download or read book Characterization and Biology of Nanomaterials for Drug Delivery written by Shyam Mohapatra and published by Elsevier. This book was released on 2018-10-05 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Characterization and Biology of Nanomaterials for Drug Delivery: Nanoscience and Nanotechnology in Drug Delivery describes the techniques successfully employed for the application of nanocarriers loaded with the antioxidant enzyme, catalase, and thus targeted to endothelial cells. Methods of nanocarrier synthesis, loading within various systems, and the characterization of nanocarriers for targeting activities are covered, as are their advantages, disadvantages and applications. Reflecting the interdisciplinary nature of the subject matter, this book includes contributions by experts from different fields, all with various backgrounds and expertise. It will appeal to researchers and students from different disciplines, such as materials science, technology and various biomedical fields. - Enables readers from different fields to access recent research and protocols across traditional boundaries - Focuses on protocols and techniques, as well as the knowledge base of the field, thus enabling those in R&D to learn about, and successfully deploy, cutting-edge techniques - Explores both current and emerging classes of nanomaterials, along with their fundamentals and applications

Download or read book Nano Micro Structured Materials for Energy and Biomedical Applications written by Bingbing Li and published by Springer. This book was released on 2018-02-08 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the latest developments of the synthesis, preparation, characterization, and applications of nano/microstructure-based materials in biomedical and energetic fields. It introduces several popular approaches to fabricating these materials, including template-assisted fabrication, electrospinning of organic/inorganic hybrid materials, biomineralization-mediated self-assembly, etc. The latest results in material evaluation for targeted applications are also presented. In particular, the book highlights the latest advances and future challenges in polymer nanodielectrics for energy storage applications. As such, it offers a valuable reference guide for scholars interested in the synthesis and evaluation of nano/microstructure-based materials, as well as their biomedical and energetic applications. It also provides essential insights for graduate students and scientists pursuing research in the broad fields of composite materials, polymers, organic/inorganic hybrid materials, nano-assembly, etc.

Download or read book Polysaccharide Nanoparticles written by Jayachandran Venkatesan and published by Elsevier. This book was released on 2022-01-11 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polysaccharide Nanoparticles: Preparation and Biomedical Applications provides detailed information on polysaccharides nanoparticles in terms of their synthesis and applications. Naturally occurring polysaccharides are widely used as food materials, particularly in Asia. Different kinds of polysaccharide materials are available from nature with various resources such as crustaceans and algae. The exploration and exploitation of polysaccharides nanoparticles from natural resource is at the heart of this book, which also explores the synthesis, preparation and applications of polysaccharides nanoparticles for tissue engineering and food applications. This is an important reference for materials scientists and bioengineers who are looking to gain a greater understanding on how polysaccharides nanoparticles are being used for a variety of biomedical applications. - Explains the major synthesis and preparation methods of polysaccharide-based nanoparticles - Demonstrates how polysaccharides nanoparticles are being used for a range of biomedical applications, including tissue engineering, drug delivery and biosensors - Assesses the major challenges and risks of using polysaccharides nanoparticles safely and effectively

Download or read book Functionalization and Characterization of Magnetic Nanoparticles for Biomedical Applications written by Kerstin Koll and published by . This book was released on 2011 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Corona Discharge Micromachining for the Synthesis of Nanoparticles written by Ranjeet Kumar Sahu and published by CRC Press. This book was released on 2019-06-13 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the fundamental and established methods for the synthesis of nanoparticles, providing readers with an organized and comprehensive insight into the field of nanoparticle technology. In addition to exploring the characterization and applications of nanoparticles, it also focuses on the recently explored corona discharge micromachining - Electrical Discharge Micromachining (EDMM) - method to synthesize inorganic nanoparticles. In the synthesis of nanoparticles, organic materials often play an indispensable role, such as providing stabilizers in the form of capping agents. This book will be of interest to advanced undergraduate and graduate students studying physics and engineering, as well as professionals and academics looking for an introduction to the nature and foundations of nanoparticle synthesis. Features: Provides diagnostic tools for the characterization of nanoparticles Explores the cutting-edge EDMM method for the synthesis and characterization of nanoparticles Discusses possible methods to overcome agglomeration of nanoparticles and achieve stable dispersion, in addition to examining the application suitability of synthesized nanoparticles

Download or read book BioMEMS and Biomedical Nanotechnology written by Mihrimah Ozkan and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices with applications to Genomics and Proteomics. Topics include gene expression profiling utilizing microarray technology; imaging and sensing for gene detection and use in DNA analysis; and coverage of advanced microfluidic devices and the Humane Genome Project.

Download or read book Micro and Nanoengineered Gum Based Biomaterials for Drug Delivery and Biomedical Applications written by Sougata Jana and published by Elsevier. This book was released on 2022-01-21 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micro- and Nanoengineered Gum-Based Biomaterials for Drug Delivery and Biomedical Applications focuses on micro- and nanotechnology in gums and biopolymers as drug and biomolecule carriers and their applications in biomedicine. Currently, natural gums and polymers are widely utilized as biocarrier systems, to deliver drugs and biomolecules to the target site, for prolonged release and the desired therapeutic effect. Natural gums and polymers are important because they are easily available from natural sources and are characteristically biodegradable, biocompatible, and nontoxic. Natural gums and polymers are also chemically modified with other polymers, in the presence of cross-linking agents, to develop scaffolds, matrices, composites, and interpenetrating polymer networks using micro- and nanotechnology. The book also discusses biological applications, such as gene delivery, cancer therapy, tissue engineering, bioimaging, and theranostics. This book is an important reference source for biomaterials scientists, biomedical engineers, and pharmaceutical scientists, who are looking to increase their understanding of how micro- and nanoengineered biomaterials are being used to create more efficient gum-based drug delivery systems. - Explains how micro- and nanoengineering is being used to make a variety of gum types more effective as nanocarriers. - Explores the major biomedical applications of various gum classes. - Assesses the major challenges of using micro- and nanotechnologies in gum-based biomedical systems.

Download or read book Biopolymer Based Micro and Nano Materials written by Nitar Nwe and published by Momentum Press. This book was released on 2015-04-27 with total page 75 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise monograph series focuses on the implementation of various engineering principles in the conception, design, development, analysis and operation of biomedical, biotechnological and nanotechnology systems and applications. Authors are encouraged to submit their work in the following core topics, but authors should contact the commissioning editor before submitting a proposal.

Download or read book Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis written by Challa S.S.R. Kumar and published by Springer. This book was released on 2018-05-02 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eighth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Biosensing and Medical Diagnosis. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Download or read book Materials for Biomedical Engineering Organic Micro and Nanostructures written by Alexandru Grumezescu and published by Elsevier. This book was released on 2019-06-18 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials for Biomedical Engineering: Organic Micro- and Nanostructures provides an updated perspective on recent research regarding the use of organic particles in biomedical applications. The different types of organic micro- and nanostructures are discussed, as are innovative applications and new synthesis methods. As biomedical applications of organic micro- and nanostructures are very diverse and their impact on modern and future therapy, diagnosis and prophylaxis of diseases is huge, this book presents a timely resource on the topic. Users will find the latest information on cancer and gene therapy, diagnosis, drug delivery, green synthesis of nano- and microparticles, and much more. - Provides knowledge of the range of organic micro- and nanostructures available, enabling the reader to make optimal materials selection decisions - Presents detailed information on current and proposed applications of the latest biomedical materials - Places a strong emphasis on the characterization, production and use of organic nanoparticles in biomedicine, such as gene therapy, DNA interaction and cancer management

Download or read book Micro and Nanotechnologies Based Product Development written by Neelesh Kumar Mehra and published by CRC Press. This book was released on 2021-09-06 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information of the nanotechnology-based pharmaceutical product development including a diverse range of arenas such as liposomes, nanoparticles, fullerenes, hydrogels, thermally responsive externally activated theranostics (TREAT), hydrogels, microspheres, micro- and nanoemulsions and carbon nanomaterials. It covers the micro- and nanotechnological aspects for pharmaceutical product development with the product development point of view and also covers the industrial aspects, novel technologies, stability studies, validation, safety and toxicity profiles, regulatory perspectives, scale-up technologies and fundamental concept in the development of products. Salient Features: Covers micro- and nanotechnology approaches with current trends with safety and efficacy in product development. Presents an overview of the recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides a comprehensive overview of the latest research related to micro- and nanotechnologies including designing, optimisation, validation and scale-up of micro- and nanotechnologies. Is edited by two well-known researchers by contribution of vivid chapters from renowned scientists across the globe in the field of pharmaceutical sciences. Dr. Neelesh Kumar Mehra is working as an Assistant Professor of Pharmaceutics & Biopharmaceutics at the Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He received ‘TEAM AWARD’ for successful commercialisation of an ophthalmic suspension product. He has authored more than 60 peer-reviewed publications in highly reputed international journals and more than 10 book chapter contributions. He has filed patents on manufacturing process and composition to improved therapeutic efficacy for topical delivery. He guided PhD and MS students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist Award and Team Award for his research output. He recently published one edited book, ‘Dendrimers in Nanomedicine: Concept, Theory and Regulatory Perspectives’, in CRC Press. Currently, he is editing books on nano drug delivery-based products with Elsevier Pvt Ltd. He has rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nanotechnologies for regulated market. Dr. Arvind Gulbake is working as an Assistant Professor at the Faculty of Pharmacy, School of Pharmaceutical & Population Health Informatics, at DIT University, Dehradun, India. He has authored more than 40 peer-reviewed publications in highly reputed international journals, four book chapters and a patent contribution. He has received outstanding awards including Young Scientist Award and BRG Travel Award for his research. He is an assistant editor for IJAP. He guided PhD and MS students for their dissertations/research projects. He has successfully completed extramural project funded by SERB, New Delhi, Government of India. He has more than 12 years of research and teaching experience in the formulation and development of nanopharmaceuticals.