Download or read book Characterization of Chemical Selectivity in Micellar Electrokinetic Chromatography written by Mark Doane Trone and published by . This book was released on 1999 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Electrokinetic Chromatography written by Ute Pyell and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a thorough theoretical description of the method, an overview on the current status of the various forms of electrokinetic capillary chromatography, plus a look forward into future developments. Focuses on the technique of electrokinetic capillary chromatography and its applications in various areas, including pharmaceutical, industrial, environmental, and biological chemistry Features invaluable information put together from experienced researchers in the area First book to discuss this technique in detail Covers a topic that is part of the exploding field of hyphenated techniques Selected international contributors working in research in this area
Download or read book Characterization of Chemical Interactions in Micellar Liquid Chromatography MLC and Micellar Electrokinetic Capillary Chromatography MEKC written by Shenyuan Yang and published by . This book was released on 1995 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Micellar Selectivity Triangle for Classification of Pseudo stationary Phase Selectivity in Electrokinetic Chromatography written by and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A novel Micellar selectivity triangle (MST) was developed to rationalize and classify the chemical selectivities for a wide variety of pseudo-phases in Electrokinetic Chromatography (EKC). The descriptors of polar selectivities for constructing the MST were derived from the linear solvation energy relationships (LSER). The effects of solvent modification of micelles, mixed-micellar systems along with surfactant type on the pseudo-phase selectivities were investigated using the MST. To quantitatively describe the similarities and differences of the chemical selecitivities, a phase selectivity ranking system was constructed on the basis of the Euclidean distance between objects. Chemometric methods including the principal component analysis (PCA), hierarchical clustering and k-means clustering were used to elucidate the classification and characterization of the micellar phases in different perspectives. The results form the MST and the chemometric methods were in generally good agreement. The micellar selectivity triangle was used as a guideline for optimizing the separation of 20 Phenylthiohydantoin (PTH) amino acids. The effects of the surfactant type and concentration, temperature and organic solvent additives on the PTH amino acids separation were evaluated. Additionally, the substituent constants of these PTH amino side chain obtained from the EKC methods were compared to those obtained from octanol-water partitioning and free energy of transferring amino acid moieties from the globular proteins interior to surface. Finally, the combined use of the unified selectivity triangle (UST), PCA and cluster analysis was explored for the comparison of the chemical selectivity between the two powerful chromatographic techniques, EKC and RPLC. The database consisted of 518 reversed-phase systems and 83 pseudo-phases. The primary factors to influence the phase selectivity of the two techniques were identified and compared. Suggestions for future works are also discussed.
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1812 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Capillary Electromigration Separation Methods written by Colin F. Poole and published by Elsevier. This book was released on 2018-04-13 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins. Edited and authored by world-leading capillary electrophoresis experts Presents comprehensive coverage on the subject Includes extensive referencing that facilitates the identification of key research developments Provides more than 50 figures and tables that aid in the retention of key concepts
Download or read book Journal of Chromatography written by and published by . This book was released on 2003 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Drug Properties written by Raimund Mannhold and published by John Wiley & Sons. This book was released on 2008-06-25 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.
Download or read book Development of Micellar Selectivity Triangle for Classification of Pseudo stationary Phase Selectivity in Electrokinetic Chromatography written by Cexiong Fu and published by . This book was released on 2005 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keywords: electrokinetic chromatography, micellar selectivity triangle, reversed phase liquid chromatography, chemometric methods, chemical selectivity.
Download or read book Studies of Micellar Electrokinetic Chromatography as an Analytical Technique in Pharmaceutical Analysis an Industrial Perspective written by Karin Stubberud and published by . This book was released on 2002 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Capillary Electrophoresis written by Patrick Camilleri and published by CRC Press. This book was released on 1997-11-25 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of capillary electrophoresis (CE) as an analytical tool has increased dramatically over the last ten years. It has changed from being an exploratory technique, mainly of academic interest, to one that is applied to solve "real" analytical problems. CE is easily adapted to its various modes of operation, often requiring little more than a change of the buffer solution, and is quickly becoming the preferred technique when analyzing minute amounts of available material. Featuring new chapters on CE analysis of inorganic ions and carbohydrates, the new edition of Capillary Electrophoresis not only presents this method as an academic tool, but also provides applications for solving "real-world" analytical problems. This updated Second Edition reflects the increasing use of CE over the last 10 years, how it is being applied, and the basic theoretical aspects of the separation and detection methodology of CE. Capillary Electrophoresis: Theory and Practice will appeal to students and professionals of analytical chemistry, physical chemistry, biochemistry, and biotechnology and includes suitable experiments designed to be attempted by university or college students, or anyone else wishing to familiarize themselves with CE.
Download or read book Capillary Electrophoresis for Food Analysis written by Richard A Frazier and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in the early 1980s, capillary electrophoresis (CE) offers a great deal of flexibility as a modern analytical technique, and has found applications within many fields of analysis, particularly pharmaceutical science and biochemistry. Until now, food analysts have had difficulties in adopting the technique due to the lack of written guidance. Capillary Electrophoresis for Food Analysis: Method Development provides basic information and the support needed to enable food analysts to utilise the technique for the development of new separation methods. Designed specifically for the needs of food analysts, the book takes the reader step by step through the process of developing and troubleshooting CE methods. Worked examples are included to make it ideal as a laboratory companion as well as a library reference source.
Download or read book Quantitative Chemical Analysis written by Daniel C. Harris and published by Macmillan. This book was released on 2010-04-30 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: QCA is the bestselling textbook of choice for analytical chemistry. It offers a modern portrait of the techniques of chemical analysis, backed by a wealth of real world applications. This edition features new coverage of spectroscopy and statistics, new pedagogy and enhanced lecturer support.
Download or read book Handbook of Food Analysis Physical characterization and nutrient analysis written by Leo M. L. Nollet and published by CRC Press. This book was released on 2004 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume handbook supplies food chemists with essential information on the physical and chemical properties of nutrients, descriptions of analytical techniques, and an assessment of their procedural reliability. The new edition includes two new chapters that spotlight the characterization of water activity and the analysis of inorganic nutrients, and provides authoritative rundowns of analytical techniques for the sensory evaluation of food, amino acids and fatty acids, neutral lipids and phospholipids, and more. The leading reference work on the analysis of food, this edition covers new topics and techniques and reflects the very latest data and methodological advances in all chapters.
Download or read book Analysis and Purification Methods in Combinatorial Chemistry written by Bing Yan and published by John Wiley & Sons. This book was released on 2004-02-03 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality measurement, control, and improvement in combinatorial chemistry Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable." To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering: * Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis * High-throughput analytical methods used to analyze the quality of libraries * High-throughput purification techniques * Analytical methods applied in post-synthesis and post-purification stages Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques. This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.
Download or read book Chromatographic Analysis of the Environment Third Edition written by Leo M.L. Nollet and published by CRC Press. This book was released on 2005-11-29 with total page 1290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromatographic Analysis of the Environment, Third Edition is a detailed handbook on different chromatographic analysis techniques and chromatographic data for compounds found in air, water, soil, and sludge. Taking on a new perspective from previous editions, this third edition discusses the parameters of each environmental compartment in a consistent format that highlights preparation techniques, chromatographic separation methods, and detection methods. Most of the data are compiled in tables and figures to elucidate the text as needed. Separate chapters approach specific aspects of sampling methods especially designed for environmental purposes, quantification of environmental analytes in difficult matrices, and data handling. The second part of the book focuses on the analysis of hazardous chemicals in the environment, including volatile organic carbons (VOCs), polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and endocrine-disrupting chemicals (EDCs). In addition, the authors feature information on compounds such as phosphates, organic acids, halogenated VOCs, amines, and n-ntirosamines, isocyanates, phthalate esters, and humic substances. Presenting important theoretical and practical aspects from sample collection to laboratory analysis, Chromatographic Analysis of the Environment, Third Edition is a unique resource of chromatographic techniques, data, and references that are useful to all scientists involved in the analysis of environmental compounds.
