Download or read book Characterization of a Morphological Mutant M 134 and Two Conidia shed Mutants E 1 and K 44 of Neurospora Crassa written by Gregory Julian Digby and published by . This book was released on 2003 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic Analysis and Characterization of Two Morphological Mutants of Neurospora Crassa written by John Timothy Chance and published by . This book was released on 1988 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of Three Mutants of Neurospora Crassa written by Shemariah E. G. Love and published by . This book was released on 2000 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of a Newly isolated Crisp like Mutant and an Osmotic sensitive Mutant of Neurospora Crassa written by Charlene Renee Jackson and published by . This book was released on 1992 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fungal Genetics Newsletter written by and published by . This book was released on 2003 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Isolation and Characterization of Conidial Separation Mutants of Neurospora Crassa written by Micah S. Kerr and published by . This book was released on 1986 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of Osmotic sensitive Mutants of Neurospora Crassa written by Jennie L. Morgan and published by . This book was released on 1985 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of the OS 8 Locus of Neurospora Crassa written by Christie Elaine Canady and published by . This book was released on 1996 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of the Morphological Mutant Crisp 5 of Neurospora Crass written by Heather Marie Cathcart and published by . This book was released on 2002 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Morphological Characterization and Genetic Analysis of a New Colonial Mutant of Neurospora Crassa written by Winfreda McCloud Council and published by . This book was released on 1991 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies of Morphology Genetics and Culture of Wild type and Morphological Mutant Strains of Neurospora Crassa written by Jay Clarence Murray and published by . This book was released on 1959 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization and Genetic Analysis of SS 18 a New Osmotic sensitive Mutant of Neurospora Crassa written by Schona Symnobia Dortch and published by . This book was released on 1998 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genetic Analysis and Characterization of SS 788 and SS 1044 New Osmotic sensitive Mutants of Neurospora Crassa written by Scott McCollum Buntin and published by . This book was released on 1995 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization of Neurospora Crassa and Fusarium Graminearum Mutants Defective in Repeat induced Point Mutation written by Kyle R. Pomraning and published by . This book was released on 2012 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutation of repetitive DNA by repeat-induced point mutation (RIP) is a process that occurs in many filamentous fungi of the Ascomycota during the sexual cycle. Concurrently, direct DNA repeats are often deleted by homologous recombination at high frequency during the sexual cycle. Thus, the processes of RIP and deletion compete to either mutate or remove repetitive DNA from the genome of filamentous fungi during sexual cycles. Both processes contribute to genome streamlining by controlling proliferation of transposable elements and by limiting expansion of gene families. While the genetic requirements for deletion by homologous recombination are well known, the mechanism behind the specific detection and mutation of repetitive DNA by RIP has yet to be elucidated as only a single gene essential for RIP, rid, has been identified. We have developed Fusarium graminearum as a model organism for the study of RIP by showing that it mutates repetitive DNA frequently during the sexual cycle and that the mutations due to RIP are dependent on rid. Further, we have sequenced a genetic mapping strain of F. graminearum (00-676-2) and identified 62,310 single nucleotide polymorphisms (SNPs) compared to the reference strain (PH-1). The SNP map will be useful for quickly mapping new mutants by bulk segregant analysis and high-throughput sequencing for which bioinformatic tools were specifically developed. The groundwork has thus been laid for identification of novel RIP mutants in F. graminearum, which being homothallic has a major advantage for identification of recessive mutations. We used a forward genetics approach to shed light on the mechanism of RIP in Neurospora crassa. Two rrr mutants that dominantly r̲educe R̲IP and r̲ecombination were characterized and identified as different mutated alleles of the same gene, rrr-1[superscript L496P] and rrr-1[superscript G325N] by bulk segregant analysis and high-throughput sequencing. Bioinformatic characterization suggests RRR-1 belongs to a previously uncharacterized group of dynamin-like proteins, which are generally involved in membrane fission and fusion. RRR-1-GFP localizes to the nuclear membrane, but not DNA, suggesting it affects RIP and recombination frequency indirectly by altering nuclear membrane dynamics during sexual development and thereby altering temporal aspects of RIP and recombination. We used a reverse genetics approach to determine whether high frequency RIP and homologous recombination of repetitive DNA during the sexual cycle are linked mechanistically or spatio-temporally. We tested strains where genes important for deletion by homologous recombination were knocked out and found all to be completely RIP competent except mre11, which, while sterile in homozygous deletion crosses, displayed lower RIP frequency in heterozygous crosses. This suggests that mre11 has roles in homologous recombination as well as non-homologous end joining may be important for RIP. Collectively, this work developed methods for efficiently mapping mutations and identified a novel protein that reduces RIP and recombination frequency but did not identify any mechanistic link between the two processes.

Download or read book Genetic Analysis and Characterization of a New Osmotic sensitive Mutant of Neurospora Crassa written by Jeffrey R. Wagner and published by . This book was released on 1994 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Isolation and Characterization of Mannitol Non utilizing Mutants of Neurospora Crassa written by Elaine M. Marino and published by . This book was released on 1982 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Characterization Genetic Analysis and Reversion of a Fungicide resistant Mutant of Neurospora Crassa written by Regan Matteil Challinor and published by . This book was released on 1996 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: