Download or read book Characterization and Synthesis of Cyclodextrin Inclusion Complexes and Their Applications as Fluorescent Probes for Sensing Biomacromolecules written by Rodolfo Francisco Gomez Biagi and published by . This book was released on 2012 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclodextrin Fundamentals Reactivity and Analysis written by Sophie Fourmentin and published by Springer. This book was released on 2018-04-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first volume of two volumes on cyclodextrins published in the series Environmental Chemistry for a Sustainable World. After a brief description of the cyclodextrin fundamentals, the first chapter by Grégorio Crini et al. provides an overview of cyclodextrin research during the last 5 years. The second chapter by Michal Řezanka discusses the synthesis of novel cyclodextrin systems by selective modifications. Then Eric Monflier et al. describes the synthesis of nanostructured porous materials based on cyclodextrins, and applications in heterogeneous catalysis and photocatalysis. The use of thermal analyses for assessing cyclodextrin inclusion complexes is reviewed in chapter 4 by Daniel Hădărugă et al. Experimental methods for measuring binding constants of cyclodextrin inclusion compounds are presented by David Landy. The second volume reviews cyclodextrin applications in medicine, food, environment and liquid crystals.
Download or read book Cyclodextrins written by Wanda Sliwa and published by John Wiley & Sons. This book was released on 2017-04-10 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by two experts working in this important field of research, the timely book covers the latest advances in the synthesis of cyclodextrins, their properties and important industrial applications. To this end, the authors describe covalent and non-covalent assemblies, cyclodextrin inclusion complexes, cyclodextrin polymers, and modified cyclodextrins, resulting in an up-to-date overview of cyclodextrin chemistry. An invaluable reference for organic and polymer chemists in academia as well as those researchers in industry working in polymer, supramolecular and pharmaceutical chemistry, as well as food, textile and cosmetic science.
Download or read book Cyclodextrin Applications in Medicine Food Environment and Liquid Crystals written by Sophie Fourmentin and published by Springer. This book was released on 2018-06-22 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the second volume of two volumes on cyclodextrins published in the series Environmental Chemistry for a Sustainable World. This volume focuses on cyclodextrin applications. The first chapter by Divya Arora and Sundeep Jaglan presents cyclodextrin-based carriers for delivery of dietary phytochemicals. The second chapter by Éva Fenyvesi et al. describes the interactions of steroids with cyclodextrins and their applications to pharmaceuticals, food, biotechnology and environment. Nazli Erdoğar and Erem Bilensoy discuss cyclodextrin-based nanosystems in targeted cancer therapy. Miriana Kfoury et al. review the use of cyclodextrins for essential oils applications in chapter 4. Hiroshi Ikeda demonstrates in chapter 5 that chromophore-appended cyclodextrins are effective for chemosensors to detect organic molecules by fluorescence or absorbance changes. Then Grégorio Crini et al. describe silica materials-containing cyclodextrin for pollutant removal. The final chapter by Chang-Chun Ling et al. summarizes the synthesis and characterization of supramolecular liquid crystals based on cyclodextrins and their applications.
Download or read book Cyclodextrins in Pharmacy written by Karl-Heinz Frömming and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems. The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation. This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
Download or read book Cyclodextrins Preparation And Application In Industry written by Zhengyu Jin and published by World Scientific. This book was released on 2018-01-10 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrins are an extremely versatile class of chemicals highly prized for their ability to incorporate a plethora of organic, inorganic and biologic guest molecules into their hydrophobic cavities and form host-guest inclusion complexes. As excellent molecular receptors, they have long been exploited in many important industries such as food and agriculture, pharmaceuticals, cosmetics, textiles, analytical chemistry and enzyme mimics.Researchers, technicians and application specialists in many industries will appreciate this handy volume that systematically discusses how cyclodextrins are applied in their industries. Special attention is devoted to the preparation of inclusion complexes, novel properties of the resultant complexes, and details on applying those properties to industry.
Download or read book Cyclodextrin Chemistry written by Zheng-Yu Jin and published by World Scientific. This book was released on 2013 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrin Chemistry covers the preparation of cyclodextrins and cyclodextrin derivatives (CDs), and their applications in industrial and non-industrial areas. An overall theme in the book is the screening of cyclodextrin glycosyltransferase (CGTase), the preparation of sugar-branched cyclodextrins and CDs, and the use of CDs for reconstructing various supermolecule systems. The specific content also includes preparation methods, spectroscopy techniques for CDs analysis, and potential applications in food packaging, nutrient fortification, medicine, cosmetics, textiles, chemicals, feed, agriculture, and environment. It summarizes the research merit of CDs in the past twenty years and also emphasizes hot topics and important areas of cyclodextrin chemistry in the future. Contents: Introduction (Jun-Rong Huang, Hai-Ning Zhuang and Zheng-Yu Jin); Enzymes in Preparing Cyclodextrins (Sheng-Jun Wu, Xiu-Ting Hu, Jin-Moon Kim and Jing Chen); Preparation and Analysis of Cyclodextrin (An-Wei Cheng, Jin-Peng Wang and Zheng-Yu Jin); Preparation of Branched-Cyclodextrins (Xing Zhou, Yao-Qi Tian and Zheng-Yu Jin); Preparation and Analysis of Cyclodextrin Derivatives (Chao Yuan, Yu-Xiang Bai and Zheng-Yu Jin); Basic Application of Cyclodextrins in Supermolecule Chemistry (Tao Feng, Ai-Quan Jiao and Zheng-Yu Jin); Use of Cyclodextrins in Food, Pharmaceutical and Cosmetic Industries (Yao-Qi Tian, Xing Zhou and Zheng-Yu Jin); Application of Cyclodextrins in Non-industrial Areas (Xue-Hong Li and Zheng-Yu Jin). Readership: Researchers and technicians in food, pharmaceutical, cosmetic and chemical industries, as well as in non-industry areas such as agriculture and environmental engineering, supermolecule and analytical chemistry.
Download or read book Cyclodextrins written by Sahar Amiri and published by John Wiley & Sons. This book was released on 2017-08-30 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The comprehensive resource for understanding the structure, properties, and applications of cyclodextrins Cyclodextrins: Properties and Industrial Applications is a comprehensive resource that includes information on cyclodextrins (CDs) structure, their properties, formation of inclusion complex with various compounds as well as their applications. The authors Sahar Amiri and Sanam Amiri, noted experts in the field of cyclodextrins, cover both the basic and applied science in chemistry, biology, and physics of CDs and offers scientists and engineers an understand of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides consisting of (α-1,4)-linked α-D-glucopyranose units. The formation of inclusion complex between CDs as host and guest molecules is based on non-covalent interaction such as hydrogen bonding or van der waals interactions and lead to the formation of supramolecular structures. These supramolecular structures can be used as macroinitiator for initiating various type of reactions. CDs are widely used in many industrial products such as pharmacy, food and flavours, chemistry, chromatography, catalysis, biotechnology, agriculture, cosmetics, hygiene, medicine, textiles, drug delivery, packing, separation processes, environment protection, fermentation, and catalysis. This important resource: Offers a basic understanding of cyclodextrins for researchers and engineers Includes information of the basic structure of cyclodextrins and their properties Reviews how cyclodextrins can be applied in a variety of fields including medicine, chemistry, textiles, packing, and many others Shows how encapsulate corrosion inhibitors became active in corrosive electrolytes to ensure delivery of the inhibitors to corrosion sites and long-term corrosion protection Cyclodextrins offers research scientists and engineers a wealth of information about CDs with particular focus on how cyclodextrins are applied in various ways including in drug delivery, the food industry, and many other areas.
Download or read book Cyclodextrins written by Francis G. Ramirez and published by Nova Science Publishers. This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrins (CDs) are capable of interacting with a large variety of guest molecules to form inclusion complexes. The authors of the chapters that form this book discuss the development of ion-selective electrodes based on selected cyclodextrins and their derivatives as selective ionophores for various drugs and their applications in pharmaceutical research; the wide range of applications of CDs in biomedical electrochemistry, focusing both on their behavior in solutions and embedded in thin films formed at the electrode surface; the general features of CDs and the progress done so far in the field of microencapsulation of pesticides in CDs; cyclodextrins as encapsulating agents for bioactive plant molecules in the pharmaceutical field; the effect of cyclodextrins on the photodegradation profile of drugs when they are used in drug formulations; applications of cyclodextrins in stabilizing or solubilizing ingredients of pharmaceutical relevance used in the food industry (commonly called nutraceuticals); the use and importance of cyclodextrins in the pharmaceutical industry; the main aspects of the crystal structures of the dimeric;-CD inclusion complexes; the influence of biologically active inorganic ions on complex formation of cyclodextrins with some aromatic carboxylic acids possessing pharmacological and biological activity; the importance of detailed characterization of the composition of substituted CDs by the example of sulfobutylether cyclodextrins; the several crystal structures of dye inclusion complexes using cyclodextrin, the preparation of DISC (dye inclusion single crystal); the structural details about the dye inclusion complex analyzed by X-ray and the properties of porphyrin DISC.
Download or read book Cyclodextrins and Their Complexes written by Helena Dodziuk and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering comprehensive and up-to-date know-how in one compact book, an experienced editor and top authors cover every aspect of these important molecules from molecular recognition to cyclodextrins as enzyme models. Chapters include reactivity and chemistry, chromatography, X-ray, NMR plus other physicochemical methods, as well as model calculations, rotaxane and catenane structures, and applications in the pharmaceutical industry. The book also discusses other applications such as in the cosmetics, toiletries, textile and wrapping industries, agrochemistry, electrochemical sensors, and devices. A must for everyone working with these substances.
Download or read book Advances in Research and Practice of Cyclodextrin Inclusion Complex written by Miao Yanfei and published by Scientific Research Publishing, Inc. USA. This book was released on 2021-07-29 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry is a subject that makes human life better. In the past few hundred years, the development of modern chemistry has also explained this meaning perfectly. Naturally, supramolecular chemistry also needs to move from theory to application, from laboratory to society, and ultimately benefit mankind. Insoluble drugs refer to poorly water-soluble drugs, which will lead to difficult absorption and transportation in vivo and low bioavailability. About 40% of the newly discovered natural active substances and nearly 60% of the chemically synthesized drugs are insoluble drugs. Their solubility (in water) is poor and it is difficult to achieve satisfactory clinical efficacy, so they have not been successfully developed into new drugs. Natural β-cyclodextrin can form supramolecular inclusion complexes with insoluble drugs, thus increasing the solubility of insoluble drugs. As a new drug delivery carrier, it has been widely studied and applied. Sulfobutyl eth-er-β-cyclodextrin is a derivative of β-cyclodextrin. Because of its good water solubility and biocompatibility, sulfobutyl ether-β-cyclodextrin can sig-nificantly increase the solubility, bioavailability and low nephrotoxicity of drugs. As a new type of injection drug delivery carrier, it has become one of the hot spots in the research and development of new drugs at home and abroad.
Download or read book Cyclodextrin written by Poonam Arora and published by BoD – Books on Demand. This book was released on 2018-04-18 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is devoted to the highly versatile and potential ingredient Cyclodextrin, a family of cyclic oligosaccharides composed of ?-(1,4)-linked glucopyranose subunits. Its molecular complexation phenomena and negligible cytotoxic effects attribute toward its application such as in pharmaceuticals, cosmetics, food, agriculture, textile, separation process, analytical methods, catalysis, environment protection, and diagnostics. Efforts have also been made to concentrate on recent research outcomes along with future prospects of cyclodextrins to attract the interest of scientists from the industry and academia. The contributions of the authors are greatly acknowledged, without which this compilation would not have been possible.
Download or read book Synthesis and Characterization of Inclusion Complexes of cyclodextrin and AB n Block Copolymers written by Kirk L. Olson and published by . This book was released on 2001 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Characterization of Novel Fluorescent Sensors Based on Terpyridine Benzoxazole and Benzothiazole Chromophores written by Xiaoman Bi and published by . This book was released on 2017 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past few decades, there has been significant interest in developing fluorescent probes, because they are useful tools for biological studies. As effective analytical techniques, fluorescent probes utilize distinct advantages offered by fluorescence detection in terms of sensitivity, selectivity, and fast response time. When fluorescent probes interact selectively with target molecules, ions or biological specimens, they can generate large optical responses. Since most ions or molecules, such as Zn2+, Ca2+, or pyrophosphate ion (PPi), are non-fluorescent, chemosensors having analyte binding-triggered fluorescence are appealing in many fields, like analytical chemistry, clinical biochemistry, medicine, and environmental science.This dissertation is devoted to the design, synthesis, and characterization of novel fluorescent sensors for Zn2+ and its associated applications. Chapter II of this dissertation presents several novel terpyridine-based fluorescent sensors with different substituents affecting the electronic and steric nature of the terpyridine (tpy) fluorophore. Sensors are designed to establish the correlation between sensor structure and its photophysical properties. Low temperature fluorescence is used to evaluate the essential role of intramolecular charge transfer (ICT) in zinc binding-induced fluorescence changes. The tpy molecular fragment has a relatively large [pi]-conjugated system which enables the potential [pi-pi] interaction between two tpy platforms and affects the fluorescence of tpy ligands. Chapter III introduces a dimeric tpy ligand containing two tpy fragments connected via a meta-phenylene unit. The detailed spectroscopic study shows that this ligand displays an attractive fluorescence turn-on, in sharp contrast to mono(tpy) ligand that shows fluorescence quenching upon binding Zn2+. The result suggests the existence of delicate structural influences on fluorescence of tpy derivatives.Chapter IV is devoted to 2-(2'-hydroxyphenyl)-1,3-benzoxazole (HBO) and 2-(2'-hydroxyphenyl)-1,3-benzothiazole (HBT) derivatives featured with a structural potential of excited-state intramolecular proton transfer (ESIPT). The study reveals additional information on the binding of HBO or HBT to metal cations, which aids the sensor design for Zn2+ and PPi detection. The molecular design aims to realize ESIPT process control upon complexation with an analyte. Chapter V is devoted to the synthesis of bis(HBO) derivatives which bind Zn2+ selectively and emit near-infrared (NIR) fluorescence as a consequence of metal ion binding-induced ESIPT turn-on. Preliminary cell stain experiment was conducted and indicated the potential biological applications.
Download or read book Cyclodextrins and Their Inclusion Complexes written by József Szejtli and published by . This book was released on 1982 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclodextrin Materials Photochemistry Photophysics and Photobiology written by Abderrazzak Douhal and published by Elsevier. This book was released on 2006-09-20 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cyclodextrin Materials Photochemistry, Photophysics and Photobiology provides to the scientific community the state-of-the art on photochemistry, photophysics and photobiology of cyclodextrin complexes in one book, and the chapters material will trigger further research in applied science connected to these small nanocapsules.The chapters contain a large number of information of value not only to readers working in the field of cyclodextrins, but also to researchers working on related areas like those of supramolecular chemistry, nanochemistry, and in general in nano- and biotechnology. * 14 Chapters reviewed by specialists working in the field* Chapters are ordered from simple to more complex systems and techniques providing developments in the field and its future* Of interest to a multidisciplinary audience working in confined nanostructures
Download or read book Studies on Inclusion Complexes of Cyclodextrin and Dyes written by Jong Seung Park and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Supramolecular chemistry covers intermolecular interactions where non-covalent bonds are involved, and many of them are based on host-guest interactions. Cyclodextrins (CDs) are cyclic oligosaccharides consisting of 6-, 7- or 8-glucose units, which are called alpha-, beta- or gamma-CDs, respectively. They have hydrophobic interior and hydrophilic exterior, and are widely being used as hosts for various organic molecules. The formation of CD inclusion complexes with a variety of dyes has continuously drawn our interests, since CDs are readily available and have ability to include dye molecules altering their properties. The present thesis covers the study of inclusion complexes of CDs and chromophore dyes, largely in two ways; rotaxane and pseudorotaxane. The stable rotaxane structure is achieved with the synthesis of dye rotaxane. The introduction of CD ring around azo chromophore provides a simple way to improve the solubility and stability of azo dye. We have shown that by incorporating proper compounds as a coupler, azo dye rotaxanes can be used as pH indicators and metal ion sensors. We have described the synthesis of novel acetylene dye rotaxane using the Pd-catalyzed reaction of Heck-Cassar-Sonogashira-Hagihara type. Its fluorescence properties in the solid state as well as in solutions are examined and compared with those of free dye. Free dye, which has tetra-carboxylic groups, is found to be highly sensitive to various metal ions, exhibiting high Stern-Volmer constants, K(SV). On the contrary, acetylene dye rotaxane exhibits much less quenching against various quenchers. The appearance of fluorescent anisotropic structure has been observed by the formation of inclusion complex between acetylene dye and gamma-CD. Its structural nature is studied by various techniques, including fluorescence, fluorescence anisotropy, wide angle X-ray scattering (WAXD) and differential scanning calorimetry (DSC) measurements. Methyl orange, an acid azo dye, forms a dimeric inclusion complex with gamma-CD, resulting in the formation stable anisotropic aggregates. Several other azo dyes are found to form anisotropic supramolecule in the presence of gamma-CD, and their structural characteristic has been discussed in terms of the number and position of solubilizing groups.
