Download or read book Characterisation of Putative Signal Transduction Molecules from plasmodium Falciparum written by Adam A. Witney and published by . This book was released on 1997 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Cloning and Characterization of Genes Encoding Putative Signal Transduction Proteins from the Human Malaria Parasite Plasmodium Falciparum written by Jiliang Li and published by . This book was released on 1997 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies of a Putative Signal Transduction Molecule from Plasmodium Falciparum written by and published by . This book was released on 1995 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Malaria Genome Projects written by Irwin W. Sherman and published by World Scientific. This book was released on 2012 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The year 2012 marks the tenth anniversary of the announcement of the genome sequence of the human malaria parasite Plasmodium falciparum and that of its mosquito vector Anopheles. The genome sequences were a result of the Plasmodium falciparum Genome Project. This book covers in detail the biology of malaria parasites and the mosquitoes that transmit the disease, how the Genome Project came into being, the people who created it, and the cadre of scientists who are attempting to see the promise of the Project realized. The promise was: a more complete understanding of the genes of the parasite (and its vector) would provide a rational basis for the development of antimalarial drugs and vaccines, allow a better understanding of the regulation of the complex life cycle in the red blood and liver cells of the human, identify the genes the parasite uses to thwart the host immune response and the ways in which the parasite evades cure by drug treatments, as well as leading to more effective measures of control transmission. The hope was that cracking the genetic code of Plasmodium and Anopheles would reveal the biochemical Achilles heel of the parasite and its vector, leading to the development of novel drugs and better methods of control, and by finding the targets of protective immunity could result in the manufacture of effective vaccines. Through a historic approach, this book will allow for those new to the field, or those with insufficient background in the sciences, to have an easier entry point. Even scientists already working in the field may better appreciate how discoveries made in the past can impact the direction of future research.
Download or read book Molecular Mechanisms of Parasite Invasion written by Barbara A. Burleigh and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogens—not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.
Download or read book International Review of Cell and Molecular Biology written by Kwang W. Jeon and published by Academic Press. This book was released on 2011-09-02 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume include Transgenic Mouse Models in Angiogenesis and Lymphangiogenesis,Morphogenesis in Giant-celled Algae,Plasmodium in the Post-Genomic Era: New Insight into the Molecular Cell Biology of Malaria Parasites, Role of Nuclear Lamins in Nuclear Organization, Cellular Signalling and Inherited Diseases, New Insights into the Mechanisms of Macroautophagy in Mammalian Cells. Covers the latest on transgenic mouse models in angiogenesis and lymphangiogenesis Includes information on morphogenesis in giant-celled algae Provides new insights into the mechanisms of macroautophagy in mammalian cells
Download or read book Expression Systems written by Michael R. Dyson and published by Methods Express (Hardcover). This book was released on 2007 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein expression is an increasingly important tool for research on gene function. What is needed is not just a lab manual providing established methods as well as the latest state-of-the-art protocols, but also clear advice on what expression system to choose when. Expression Systems: Methods Expressuniquely fills this need. It covers expression across a broad range of systems, including the following. *Baculovirus expression vectors *CHO cells *E. coli *HEK293-EBNA1 cells *Lactococcus lactis and other gram positive bacteria *S. cerevisiae *transfected insect cells *Pichia pastoris *mammalian cells using BacMam viruses *lentiviral vectors *wheat germ cell-free system The book takes the reader through how to make an informed choice of appropriate system, taking into account the protein target, the time involved, the ultimate use of the expressed protein, and the laboratory equipment required. It also provides step-by-step methods for each system. In addition, the book describes the optimisation of expression strategies, expression engineering using ribosome display, and how to select protein variants with improved expression. Every chapter discusses the merits and limitations of the approaches available, describes the key techniques in full practical detail, and provides sensible advice for immediate use at the bench. In summary, Expression Systems: Methods Expressis a comprehensive laboratory manual and information resource for researchers at all levels, from postgraduate student to principal investigator.
Download or read book Genetics Abstracts written by and published by . This book was released on 2001 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunization Against East Coast Fever Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment written by Subhash P. Morzaria and published by ILRI (aka ILCA and ILRAD). This book was released on 1986-01-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Medical Parasitology written by Joseph Marr and published by Elsevier. This book was released on 2002-12-10 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable, new source, Molecular Medical Parasitology is the only text of its kind -- one that applies broad concepts and current scientific advances from both molecular biology and biochemistry to the study of parasitic organisms. An internationally renowned team of scientists and physicians places parasites in their broad biological contexts while still emphasizing the specifics that differentiate these organisms. Not only will researchers and faculty in parasitology find this an indispensable guide, physicians will benefit from the thorough coverage molecular biology and biochemistry's current influences on treatment and management of parasitic diseases. Features the most up-to-date scientific methods behind the medical management of parasitic diseases Applies the most current synthesis of molecular biology and biochemistry to parasitic organisms Contains many informative figures and clear illustrations
Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1990 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Signal Transduction by Reactive Oxygen and Nitrogen Species Pathways and Chemical Principles written by H.J. Forman and published by Springer Science & Business. This book was released on 2006-02-17 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Henry Jay Forman, Jon Fukuto and Martine Torres "Research is to see what everybody else has seen and to think what nobody else has thought. " -- Albert Szent-Gyorgyi Several years ago, one of us put together a book that dealt with various aspects of oxidative stress and introduced the concept of signal transduction by oxidants. Since then, the interest in the mechanisms by which reactive oxygen and nitrogen species (ROS/RNS) can modulate the cell’s response has tremendously grown, paralleling the intense efforts towards identifying new signaling pathways in which phosphorylation/dephosphorylation events take center stage. Evidence is now mounting that production of these species by the cells is required for their function from growth to apoptosis and numerous signaling pathways have been identified where the participation of ROS and RNS is apparent (see Chapters 11-14, 16 and 18). Thus, the field is no more limited to the group of free radical aficionados who have pioneered this area of research but has now gone mainstream. While it is satisfactory for those of us who have been working on this topic for a long time, it has the risk of becoming the “fashionable” motto where those molecules, still mysterious to some, become responsible for everything and anything.
Download or read book Malaria written by Irwin W. Sherman and published by Amer Society for Microbiology. This book was released on 1998-01 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every 30 seconds a death is caused by Malaria. This book brings together recent advances in our understanding of the basic biology, genetics and pathogenesis of malaria, to facilitate the rapid generation of new insights and interventions. Each chapter is written by a leading expert(s), and serves as both a useful introduction to the area and a helpful set of references. Malaria: Parasite Biology, Pathogenesis and Protection is a useful entry point for graduate and medical students, scientists and individuals engaged in a subspecialty of Malaria research, as well as those who are simply interested in getting a grasp on the present status of this ever burgeoning public health problem.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1796 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Epidemiology of Theileriosis in Africa written by R. A. I. Norval and published by ILRI (aka ILCA and ILRAD). This book was released on 1992-01-01 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theileriosis is the name given to infections caused by several species of Theileria, the most important of which in Africa are Theileria annulata and Theileria parva. Their distributions in the continent are distinct, and follow that of their main field tick vectors. The annulata occurs in North Africa and the Nile River Valley, and the parva in sub-Saharan eastern, central, and southern Africa. This book reviews the work on theileriosis since 1902 from an historical, biological, ecological, epidemiological, and economic point of view. The results shed new light on poorly understood areas in theileriosis and at the same time assist with the development of more robust control strategies. Focuses on a tick borne parasite that threatens twenty-five million cattle in Central and East Africa Assembles all current data on the epidemiology of theileriosis in Africa Lays the groundwork for future studies
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book South African Journal of Science written by and published by . This book was released on 1998 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt:
