Download or read book Channels Carriers and Pumps written by Wilfred D. Stein and published by Elsevier. This book was released on 2014-12-09 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Plant Nutrition written by Walter Horst and published by Springer Science & Business Media. This book was released on 2006-05-18 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a compilation of extended abstracts of all papers presented at the 14th International Plant Nutrition Colloquium. Over 500 oral and poster presentations illustrate current knowledge and research emphasis in this subject, providing a comprehensive view of the state of plant nutrition research.

Download or read book Transport And Diffusion Across Cell Membranes written by Wilfred Stein and published by Elsevier. This book was released on 2012-12-02 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Download or read book Ionic Channels of Excitable Membranes written by Bertil Hille and published by Sinauer Associates, Incorporated. This book was released on 1992 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.

Download or read book Membranes to Molecular Machines written by Mathias Grote and published by University of Chicago Press. This book was released on 2019-07-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences—from practitioner to historian to philosopher.

Download or read book Transporters as Drug Targets written by Gerhard F. Ecker and published by John Wiley & Sons. This book was released on 2017-04-10 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2023-05-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Color print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.

Download or read book Introduction to Cellular Biophysics Volume 1 written by Armin Kargol and published by Morgan & Claypool Publishers. This book was released on 2019-03-29 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Download or read book Fractal Physiology written by James B Bassingthwaighte and published by Springer. This book was released on 2013-05-27 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: I know that most men, including those at ease with the problems of the greatest complexity, can seldom accept even the simplest and most obvious truth if it be such as would oblige them to admit the falsity of conclusions which they have delighted in explaining to colleagues, which they have proudly taught to others, and which they have woven, thread by thread, into the fabric of their lives. Joseph Ford quoting Tolstoy (Gleick, 1987) We are used to thinking that natural objects have a certain form and that this form is determined by a characteristic scale. If we magnify the object beyond this scale, no new features are revealed. To correctly measure the properties of the object, such as length, area, or volume, we measure it at a resolution finer than the characteristic scale of the object. We expect that the value we measure has a unique value for the object. This simple idea is the basis of the calculus, Euclidean geometry, and the theory of measurement. However, Mandelbrot (1977, 1983) brought to the world's attention that many natural objects simply do not have this preconceived form. Many of the structures in space and processes in time of living things have a very different form. Living things have structures in space and fluctuations in time that cannot be characterized by one spatial or temporal scale. They extend over many spatial or temporal scales.

Download or read book Red Cell Membrane Transport in Health and Disease written by Ingolf Bernhardt and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: 51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.

Download or read book Calcium Entry Channels in Non Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Download or read book The Neuron written by Irwin B. Levitan and published by Oxford University Press, USA. This book was released on 2002 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Download or read book Anatomy Physiology written by Lindsay Biga and published by . This book was released on 2019-09-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: A version of the OpenStax text