Download or read book Central Nervous System Malignancies An Issue of Hematology Oncology Clinics of North America E Book written by David A. Reardon and published by Elsevier Health Sciences. This book was released on 2021-11-24 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Hematology/Oncology Clinics, guest editor David A. Reardon︎ brings his considerable expertise to the topic of Central Nervous System Malignancies. Top experts in the field cover key topics such as CNS Metastases, Leptomeningeal Disease, Neurofibromatoses, Imaging Advances for CNS Tumors, and more. - Contains 16 relevant, practice-oriented topics including CNS Tumor Classification: An Update on the Integration of Tumor Genetics; Etiology and Epidemiology of CNS Tumors; The Evolving Role of Neurosurgical Intervention for CNS Tumor ; Update on Radiation Therapy for CNS Tumors; and more. - Provides in-depth clinical reviews on CNS Malignancies, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Transformative Violence written by Erica Marat and published by Oxford University Press. This book was released on 2024-03-11 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Transformative Violence, Erica Marat explains how certain violent acts can trigger unprecedented levels of mobilization in defense of the victims. Marat shows that cases of violence that spark large public reaction share a similar set of traits. They include mobilization of both grassroots and national-level activists, a type of victim that resonates with the broader public, and a visual narrative of the victim's suffering. While all three occur independently, it is the union of these events that captures the attention of the public at large, prompts it to act, and eventually leads to policy changes.

Download or read book Neuro Oncology Compendium for the Boards and Clinical Practice written by Maciej M. Mrugala and published by Oxford University Press. This book was released on 2023-02-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renowned experts in the neuro-oncological field bring their expertise together for Neuro-Oncology Compendium for the Boards and Clinical Practice. This volume reviews the core topics of neuro-oncology including adult and pediatric neuro-oncology, management, central nervous system tumor complications, genetic considerations, and more. With a focus on updated treatments and terminology, this volume is designed to comprehensively review all major facets of neuro-oncology so that physicians-in-training may prepare for the board review and practicing specialists can stay up to date in their treatment of patients. This essential text includes hundreds of figures and tables, succinct review flashcards, end-of-chapter questions and answers, as well as end-of-volume exams so readers can review and test their own comprehension. Each chapter has been reviewed by the editors to ensure cohesive board-level verbiage, emphasizing practical clinical knowledge. Neuro-Oncology Compendium for the Boards and Clinical Practice is up-to-date and comprehensive, eliminating the need for multiple sources of study. Key features of this volume include: -End of chapter flashcards to summarize key content -End of chapter Questions and Answers for review -Practice exams to simulate board questions -Updated terminology and practices -Complimentary images and tables to support learning

Download or read book Radiation Oncology Study Guide written by Ravi A. Chandra and published by Springer Nature. This book was released on 2020-11-16 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this popular text remains a comprehensive study and review aid for the radiation oncology trainee and practicing radiation oncologist. The updated Radiation Oncology Study Guide, 2e maintains its robust Q&A format, and has been comprehensively updated to include the latest staging information and treatment methods. Answer rationales have been modified to a more readable, high yield bulleted format. Each chapter covers a major disease site and is divided into two main parts: Questions & Answers and Rationale. Questions review the scope of clinical practice, spanning from initial presentation to complications of treatment. General content and work-up questions emphasize “pearls” of epidemiology, anatomy, pathology, clinical presentation, and staging. Treatment content questions not only review evidence-based data guiding treatment recommendations, but also practical aspects of radiation treatment planning, pertinent radiobiology and physics, and complications of treatment. This book is an ideal resource for physicians-in-training to prepare for initial written and oral exams and physicians in practice to maintain their skills and prepare for maintenance of certification longitudinal and written exams.

Download or read book Glioblastoma Part II Molecular Targets and Clinical Trials An Issue of Neurosurgery Clinics of North America written by Linda M. Liau and published by Elsevier Health Sciences. This book was released on 2021-04-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Dr. Linda M. Liau, is dedicated to Glioblastoma: Molecular and Clinical Trials. This issue is one of four selected each year by the series consulting editors, Drs. Russell R. Lonser and Daniel K. Resnick. Topics will include—but are not limited to—Pathology & Molecular Markers, Cellular States & Genetic Diversity in Glioblastoma, Mismatch Repair in Glioblastoma Resistance, Genetic Susceptibility in Brain Cancer, Pediatric Gliomas: Molecular Landscape & Emerging Targets, Molecularly Targeted Clinical Trials, Novel Radiation Sensitizers, Immunotherapy Checkpoint Inhibitors, Brain Tumor Vaccines, CAR T Cells, Oncolytic Virotherapy, Targeting Cancer Stem Cells, Therapeutic Delivery to CNS, Theranostics: Dual Modality PET Tracers, and Neuroimaging & Novel Response Assessments.

Download or read book Novel Diagnostic and Therapeutic Strategies in the Management of Cerebral Gliomas written by Valeria Barresi and published by Frontiers Media SA. This book was released on 2024-10-29 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral gliomas account for 45% of all primary central nervous system (CNS) tumors. The median survival after the initial diagnosis of glioblastoma (GBM) is only 15 months, and less than 10% of patients survive three years post-diagnosis. Surgical treatment followed by adjuvant therapies such as radiotherapy and chemotherapy represents the classical strategy in glioma management. The revised WHO 2016 classification now distinguishes the oligodendrogliomas with 1p19q codeletion and IDH mutation from the astrocytomas with or without IDH mutations, thereby creating homogenous and pathologically distinct subgroups. While the status of gene expression and mutations define components of GBM subtypes, it was also found that response to therapies was different for each subtype, suggesting that personalized treatment based on genomic alterations could lead to a more favorable outcome for this disease.

Download or read book Epigenetic and Metabolic Regulation of Primary and Metastatic Brain Cancers written by Ryan Gimple and published by Frontiers Media SA. This book was released on 2023-10-03 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fast Facts Glioblastoma written by Mairéad McNamara and published by Karger Medical and Scientific Publishers. This book was released on 2020-02-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma (also known as glioblastoma multiforme) is a malignant intrinsic tumor thought to arise from populations of stem/progenitor cells in the brain. It is the most common aggressive intrinsic brain tumor in adults, with the potential to spread rapidly within the brain. Patients with glioblastoma face a poor prognosis, with median overall survival of approximately 15 months. However, our growing understanding of the molecular biology of gliomas means that this outlook may be improving. The identification of clinically relevant subgroups defined by specific genetic mutations is challenging the traditional delineation between low- and high-grade gliomas that has been based on histological appearance and imaging. Indeed, it is becoming clear that, as a molecular entity, a glioblastoma, which by traditional classification is a grade IV glioma, may present with a lower grade initially and then become more aggressive – an important addition to the established concept. The care of a patient with a glioblastoma requires a coordinated approach delivered by a multidisciplinary team, with the aim of maintaining quality of life for as long as possible. Here, we provide a concise overview of the diagnosis and management of glioblastoma, as well as discussion of our emerging understanding of the molecular drivers that are helping us to delineate different patient subgroups. These subgroups will, hopefully, allow more targeted treatments in the future. This resource will be of interest to all those involved in caring for patients with this aggressive brain tumor, including neurologists, neurosurgeons, neuro-oncologists, radiation oncologists, palliative care specialists, specialist nurses and medical students. Contents: • Epidemiology, pathophysiology and classification • Clinical presentation • Diagnosis • Management • Treatment of associated conditions • Emerging research and treatment

Download or read book FRONTIERS IN ONCOLOGY EDITOR S PICK 2021 written by Giuseppe Giaccone and published by Frontiers Media SA. This book was released on 2022-05-17 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are pleased to introduce the 2021 Frontiers in Oncology: Editor’s Pick collection, showcasing articles stimulating interest in the field, carefully selected by our Field Chief Editor, Prof. Giuseppe Giaccone, of Weill Cornell Medicine. With this ebook we aim to highlight and disseminate important findings across the domains of cancer research, capturing the multidisciplinary and inclusive approach our journal takes towards advancing the field of oncology and supporting the global effort towards improved quality of life and patient survival. 2021 was a year which saw our highest journal impact factor yet, international community growth, and a record-breaking number of articles to choose from. We wish to elevate the contributions made by authors, encourage readership and innovation through our open-access philosophies, and thank our Editorial Board for their continued hard work and collaboration.

Download or read book Therapy in Neurology An Issue of Neurologic Clinics E Book written by Jose Biller and published by Elsevier Health Sciences. This book was released on 2020-12-02 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurologic Clinics, guest edited by Dr. José Biller, is devoted to Therapy in Neurology. This issue is one of four selected each year by the series Consulting Editor, Dr. Randolph W. Evan. Articles in this issue include: Update on CGRP Antagonism in the Treatment of Migraine, Advances in the Treatment of Multiple Sclerosis, Advances in the Treatment of Neuromyelitis Optica Spectrum Disorder, Advances and ongoing controversies in PFO closure and cryptogenic stroke, Advances in neuromodulation/neurostimulation in Neurology, Advances in the treatment of muscular dystrophies and motor neuron disorders, Advances in the management of small fiber neuropathies, Update in the treatment of Idiopathic Intracranial Hypertension, What is new in neuro-oncology?, Advances in the surgical management of epilepsy, Treatment of Viral Encephalitis, An update on Botulinum toxin in neurology, Cannabinoids in neurological illnesses, and Pitfalls in Transitioning Neurological Care of the Developmentally Disabled from Pediatric to Adult Providers.

Download or read book Diffusion Weighted MR Imaging of the Brain Head and Neck and Spine written by Toshio Moritani and published by Springer Nature. This book was released on 2021-05-30 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book, now in an updated and extended third edition, systematically covers the use of diffusion-weighted (DW) MR imaging in all major areas of neuroradiology, including imaging of the head and neck and the spine as well as the brain. The authors guide the reader from the basic principles of DW imaging through to the use of cutting-edge diffusion sequences such as diffusion tensor (DTI) and kurtosis (DKI), fiber tractography, high b value, intravoxel incoherent motion (IVIM), neurite orientation dispersion and density imaging (NODDI), and oscillating gradient spin echo (OGSE). Pathology, pathophysiology, and patient management and treatment are all thoroughly discussed. Since the early descriptions by LeBihan and colleagues of the ability to image and measure the micromovement of water molecules in the brain, diffusion imaging and its derivatives have contributed ever more significantly to the evaluation of multiple disease processes. In comprehensively describing the state of the art in the field, this book will be of high value not only for those who deal routinely with neuro-MR imaging but also for readers who wish to establish a sound basis for understanding diffusion images in the hope of extending these principles into more exotic areas of neuroimaging.

Download or read book Case reports in radiation oncology 2022 written by Benjamin Clasie and published by Frontiers Media SA. This book was released on 2023-08-21 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 365 Days of Progress In Neuro Oncology and Neurosurgical Oncology written by David D. Eisenstat and published by Frontiers Media SA. This book was released on 2023-10-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: “365 Days of Progress” is part of a wider series of Research Topics across Frontiers in Oncology, hosted by our Specialty Chief Editors, showcasing popular articles from 2021 igniting interest in the field. This Research Topic aims to highlight the work featured and spark further discussion. The Neuro-Oncology and Neurosurgical Oncology field is continuously evolving, therefore we are seeking to understand developments and perspectives on articles that have attracted attention throughout the year. We welcome Opinions, Perspectives, and Mini-Review article types to facilitate this discussion. We also welcome updated original data following the research featured in this collection. Please note only papers that are relevant and add a significant contribution to the discussion articles will be considered. The chosen manuscripts are : - Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device - A Phase 2 Randomised Clinical Trial Assessing the Tolerability of Two Different Ratios of Medicinal Cannabis in Patients With High Grade Gliomas - Evolution of Experimental Models in the Study of Glioblastoma: Toward Finding Efficient Treatments - The Role of Microglia in Glioblastoma - A Review of Newly Diagnosed Glioblastoma - A Position Statement on the Utility of Interval Imaging in Standard of Care Brain Tumour Management: Defining the Evidence Gap and Opportunities for Future Research - Surgical Management of Tentorial Notch Meningioma Guided by Further Classification: A Consecutive Study of 53 Clinical Cases - Development of a Nomogram Based on Preoperative Bi-Parametric MRI and Blood Indices for the Differentiation Between Cystic-Solid Pituitary Adenoma and Craniopharyngioma

Download or read book Oncology in the Precision Medicine Era written by Ravi Salgia and published by Springer Nature. This book was released on 2019-12-17 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprehensively reviews oncology in the precision medicine era of personalized care, latest developments in the field, and indications and clinical trials for the treatment of cancer with targeted therapies, immunotherapy, and epigenetic modulators. It thoroughly addresses concerns of various types of cancers including cancers of the head and neck, lung, colon, esophagus, bladder, pancreas, and breast; melanoma; multiple myeloma; hepatocellular carcinoma; renal cell carcinoma; and sarcomas. It is organized and written in a format that is easy to follow for both clinicians and non-clinical scientists interested in personalized medicine. Chapters cover the identification of the clinical problem and summary of recent findings, tumor biology and heterogeneity, genomics, examples of simple and complex cases, biological pathways, future clinical trials, and financial considerations. Oncology in the Precision Medicine Era: Value-Based Medicine will serve as a useful resource for medical oncologists and healthcare providers tailoring medicine to the needs of the individual patient, from prevention and diagnosis to treatment and follow up.

Download or read book Understanding Tumor Heterogeneity and Altered Metabolism in Gliomas written by Yaohua Liu and published by Frontiers Media SA. This book was released on 2022-11-11 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cancer Chemotherapy Immunotherapy and Biotherapy written by Bruce A. Chabner and published by Lippincott Williams & Wilkins. This book was released on 2024-06-18 with total page 1541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on individual patient needs, Cancer Chemotherapy, Immunotherapy and Biotherapy: Principles and Practice, Seventh Edition, provides thorough, comprehensive information from Drs. Bruce A. Chabner, Dan L. Longo, and an authoritative team of clinicians and scientists working at renowned cancer centers across the globe. It covers fundamental information about mechanism of action, pharmacokinetics, clinical toxicity, and drug interactions, all essential to the safe and effective use of the drug.

Download or read book Medicines for Cancer written by Surya K. De and published by Elsevier. This book was released on 2023-04-18 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicines for Cancer: Mechanism of Action and Clinical Pharmacology of Chemo, Hormonal, Targeted, and Immunotherapies covers most known anti-cancer therapeutics. Cancer is the second leading cause of death worldwide, with its various forms resulting in nearly one out of every six mortalities each year. This book describes all US FDA-approved drugs (up to 2021), such as small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, cell therapy, and immunotherapies, along with information on their generic and brand names, medical uses, details dosage, mechanisms of actions, pharmacokinetics and side effects. Chemical structures of small molecules, small peptides, antibody-drug conjugates are also provided. This book is ideal for medicinal chemists, oncologists, and pharmacologists, but it will also be indispensable for professional researchers, whether they are working in the clinic or the pharmaceutical industry. - Covers precise information on each drug treatment - Catalogues and lists all FDA-approved drugs for cancer group by chemical classes - Provides easy access to specific drugs