Download or read book Cerebrovascular Pathology in Alzheimer s Disease written by Jack C. De La Torre and published by . This book was released on 1997 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do changes in the cerebrovascular system precede or follow clinical onset of Alzheimer's Disease? In this book a distinguished group of contributors addressES this question and explores the extent to which the pathological changes found in the brains of p
Download or read book Cerebrovascular Pathology in Alzheimer s Disease written by Jack C. De La Torre and published by . This book was released on 1997 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathogenesis and progression of Alzheimer's disease is examined from the less-usual vantage point of the dysfunctional cerebrovasculature on amyloid formation, loss of neuronal homeostasis, synaptic changes, metabolic compromise, and cognitive decline. The book explores whether the cerebrovascular changes precede or follow clinical onset of the disease and the extent to which the pathological changes found in the brains of patients with Alzheimer's disease are related to cerebral blood flow, perfusion, and blood-brain barrier dysfunction.
Download or read book Vascular Disease Alzheimer s Disease and Mild Cognitive Impairment written by David Libon and published by Oxford University Press, USA. This book was released on 2020 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cerebrovascular and Alzheimer disease often occur together, but are usually studied apart. This book offers a timely integrated approach to both diseases. Beginning with a section on epidemiology and neuropsychology, this volume goes on to discuss and explore the neuropathological and neurophysiological mechanisms of these disorders. This book then develops a novel concept of an Alzheimer disease/vascular dementia spectrum. Sections on neuroimaging, as well as treatments and interventions follow. The editors have succeeded in gathering an impressive group of clinicians and scientists, who are well qualified by their achievements and leadership to make important contributions to this new integrated approach to dementing disorders. This important book should have broad appeal to anyone studying or caring for patients with dementing disorders, as it is comprehensive, yet focused on a unitary, complementary and pragmatic approach"--
Download or read book Cerebral Amyloid Angiopathy in Alzheimer s Disease and Related Disorders written by M.M. Verbeek and published by Springer Science & Business Media. This book was released on 2000-07-31 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral amyloid angiopathy (CAA) is a distinctive abnormality of small cerebral blood vessels, one that has intrigued neuroscientists for decades. The time seems right for a book which examines the phenomenon of CAA using a multifaceted approach: What does it produce clinically? How might CAA be imaged? What are the crucial biochemical/cellular events within cerebral vessel walls that lead to CAA? How can in vitro or transgenic experimental systems be used to understand the etiology of, or even potential treatments for, CAA? The editors have assembled key figures in the field of CAA research to examine these (and other) questions in a series of focused chapters that address specific issues of importance in understanding CAA and its clinical manifestations. Comprehending the biology and pathogenesis of this fascinating vascular lesion may even provide clues to less common forms of cerebral microvascular disease that have been recognized for decades (hypertensive microangiopathy) or more recently (CADASIL).
Download or read book Vascular Dementia written by Robert H. Paul and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary survey of our current understanding of the biological and clinical aspects of vascular disease. The authors describe its basic mechanisms, its clinical characteristics, its pharmacological management, and the use of neuroimaging methods to investigate it. The complex relationship between VaD and AD is also fully explored with chapters on how these processes interact and how one disease may lower the threshold for clinical expression of the other.
Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. - Discusses the complexities involved with aging and Alzheimer's disease in Down syndrome - Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age - Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research
Download or read book Cerebral Ischemia and Dementia written by Alexander Hartmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: In contrast to dementia of the Alzheimer type, the subject of dementia subsequent to cerebral ischemia has been discussed rather rarely. Now this book provides a summary of the brain morphology, neurochemistry and clinical aspects of dementia subsequent to cerebral ischemia. The contributions discuss the similarities and differences between the two predominant dementia types. The broad range of aspects cover 1) the morphology and morphobiology of brain tissue during aging and under the two pathological condi- tions, 2) the neuropathochemistry of post mortem brain tissue of patients as well as brain tissue from experimental animals, 3) CSF changes during aging and in dementia states and 4) clinical research, mainly using brain imaging tech- niques to differentiate between dementia types and to find a basis for rational therapeutic approaches.
Download or read book Alzheimer s Disease written by Jack C. De La Torre and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of TGF beta 1 in Mediating Cerebrovascular Pathology from Cell Culture to Alzheimer s Disease Patients written by Veronica Lifshitz and published by . This book was released on 2013 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cerebrovascular Disease and Dementia Second Edition written by John O'Brien and published by CRC Press. This book was released on 2004-02-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: When discussing dementia, the medical literature tends to focus on Alzheimer's disease, leaving other dementias, such as those relating to cerebrovascular disease, somewhat neglected, despite being a common cause of cognitive decline in later life. However, in recent years there has been a remarkable transformation in our knowledge about the role of vascular factors in cognitive decline and dementia. It is now recognized that cerebrovascular disease influences clinical expression of cognitive and non cognitive features in a variety of cognitive disorders, including Alzheimer's disease itself. Cerebrovascular Disease, Cognitive Impairment and Dementia reviews what is now known about the relationship between cerebrovascular disease and dementia. It describes new knowledge of how vascular processes interact with neuro-degenerative ones, and how both appear to be risk factors for the other. The book contains contributions from leading international experts and covers epidemiology, diagnosis, clinical features, investigations (including neuroimaging), management, and service and caregiver issues. The second edition of this pioneering text is completely revised and emphasizes the primary and secondary prevention of cerebrovascular disease and the treatment of cognitive impairment. A truly comprehensive yet accessible text which puts basic research findings in a clinically relevant context, this book will appeal to psychiatrists, neurologists, geriatricians, allied health professionals, and others involved in the care of patients with cognitive impairment and dementia.
Download or read book Down Syndrome and Alzheimer s Disease written by Vee P. Prasher and published by Radcliffe Publishing. This book was released on 2006 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the underlying biological abnormalities of Dementia in Alzheimer's Disease (DAD) in people with Down syndrome. Brings together recent research findings relating to the neuropathology, genetics, blood markers and neurophysiology of Alzheimer's disease in older adults with Down syndrome.
Download or read book Cerebrovascular Disease and Dementia written by Edmond Chiu and published by CRC Press. This book was released on 2000-01-13 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in dementia are currently dominated by an overwhelming interest in Alzheimer's Disease. With considerable advances taking place in the understanding of non-AD dementias, the authors were aware of a need for a comprehensive text with a holistic multidisciplinary approach to the subject. They have brought together an international team of experts to produce the most detailed and up-to-date text available covering management and prevention, and highlighting the relationship between cerebrovascular disease and dementias. Targeted primarily at clinicians, this book is an essential reference for all those working with the elderly.
Download or read book Cerebral Microbleeds written by David J. Werring and published by Cambridge University Press. This book was released on 2011-05-26 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a leading cause of death and disability throughout the world. About one in three symptomatic strokes are due to disease of small perforating arteries; however, most effective interventions are targeted at disease of large arteries. The underlying mechanisms and treatment of small vessel disease remain poorly understood. Microbleeds have emerged as a critical imaging marker of small vessel disease, being found in all types of stroke. With increasing evidence that microbleeds are caused by hypertensive arteriopathy and cerebral amyloid angiopathy, they are likely to play a strong future role in increasing our understanding of the causes of small vessel disease and the potential link between cerebrovascular disease and neurodegeneration. Cerebral Microbleeds summarizes our current knowledge, bringing together expert research from global authorities in the field. This authoritative and systematic text will be of interest to all clinical researchers and physicians in the fields of stroke and cognitive impairment.
Download or read book The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease written by Shereen Nizari and published by Frontiers Media SA. This book was released on 2022-05-26 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Behavioral and Cognitive Neurology of Stroke written by Olivier Godefroy and published by Cambridge University Press. This book was released on 2007-01-18 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: The care of stroke patients has changed dramatically. As well as improvements in the emergency care of the condition, there have been marked advances in our understanding, management and rehabilitation of residual deficits. This book is about the care of stroke patients, focusing on behavioural and cognitive problems. It provides a comprehensive review of the field covering the diagnostic value of these conditions, in the acute and later phases, their requirements in terms of treatment and management and the likelihood and significance of long-term disability. This book will appeal to all clinicians involved in the care of stroke patients, as well as to neuropsychologists, other rehabilitation therapists and research scientists investigating the underlying neuroscience.
Download or read book The Neuropathology of Dementia written by Margaret M. Esiri and published by Cambridge University Press. This book was released on 2004-07-22 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.
Download or read book Cerebral Small Vessel Disease written by Leonardo Pantoni and published by Cambridge University Press. This book was released on 2014-05 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
