Download or read book Central Regulation of Energy Metabolism With Special Reference To Circadian Rhythm written by Katsuya Nagai and published by CRC Press. This book was released on 1992-06-26 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This excellent book describes the roles of the suprachiasmatic nucleus (SCN) of the hypothalamus as a regulatory center of homeostatic mechanism and a circadian oscillator in mammals, including humans. The authors emphasize two important points based on their findings: 1) SCN plays a critical role in central regulation of energy metabolism through which a constant supply of glucose to the central nervous system (CNS) is well maintained; and 2) neurons responsible for the regulation of energy metabolism are located in the ventrolateral part of the SCN and receive retinal neural inputs through both the retinohypothalamic tract and the geniculohypothalamic tract. The authors then discuss the evolutionary importance of these points to the survival of mammals on earth. Other topics examined include the involvement of light in the regulation of neural activity of the autonomic nervous system through the retina and SCN, in addition to the relation of the SCN with regulations of other autonomic nerve functions, such as blood pressure and body temperature. Central Regulation of Energy Metabolism with Special Reference to Circadian Rhythm is important reading for researchers and students in neuroendocrinologists, neurobiologists, biochemists, endocrinologists, physiologists, chronobiologists, psychologists, pharmacologists, and others interested in the topic.
Download or read book Central Regulation of Energy Metabolism With Special Reference To Circadian Rhythm written by Katsuya Nagai and published by Routledge. This book was released on 2022-03-22 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This excellent book describes the roles of the suprachiasmatic nucleus (SCN) of the hypothalamus as a regulatory center of homeostatic mechanism and a circadian oscillator in mammals, including humans. The authors emphasize two important points based on their findings: 1) SCN plays a critical role in central regulation of energy metabolism through which a constant supply of glucose to the central nervous system (CNS) is well maintained; and 2) neurons responsible for the regulation of energy metabolism are located in the ventrolateral part of the SCN and receive retinal neural inputs through both the retinohypothalamic tract and the geniculohypothalamic tract. The authors then discuss the evolutionary importance of these points to the survival of mammals on earth. Other topics examined include the involvement of light in the regulation of neural activity of the autonomic nervous system through the retina and SCN, in addition to the relation of the SCN with regulations of other autonomic nerve functions, such as blood pressure and body temperature. Central Regulation of Energy Metabolism with Special Reference to Circadian Rhythm is important reading for researchers and students in neuroendocrinologists, neurobiologists, biochemists, endocrinologists, physiologists, chronobiologists, psychologists, pharmacologists, and others interested in the topic.
Download or read book Circadian Rhythms and Metabolism written by Etienne Challet and published by Frontiers Media SA. This book was released on 2017-09-18 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major breakthroughs of the last decade in the understanding of energy homeostasis is the identification of a reciprocal control between circadian rhythmicity and cellular metabolism. Circadian rhythmicity is a fundamental endogenous process of almost every organism living on Earth. For instance, the alternation of hunger and satiety is not continuous over 24 h, but is instead structured in time along the light/dark cycle. In mammals, the temporal organization of metabolism, physiology and behavior around 24 h is controlled by a network of multiple cellular clocks, synchronized via neuronal and hormonal signals by a master clock located in the suprachiasmatic nuclei of the hypothalamus. This central circadian conductor in the brain is mainly reset by ambient light perceived by the retina, while secondary circadian clocks in other brain areas and peripheral organs can be reset by meal timing. Chronic disruption of circadian rhythms, as seen in human shift-workers (up to 20% of the active population), has been associated with the development of a number of adverse mental and metabolic conditions. Understanding of the functional links between circadian desynchronization and overall health in animal models and humans, however, is still scarce. Interactions between circadian clocks and metabolism can occur at different levels: the molecular clockwork, internal synchronization via neuro-hormonal signals, or external synchronization via photic or feeding cues. This Research Topic comprises a number of reviews as well as research and methods articles that feature recent advancements in the mechanisms linking circadian clocks with energy metabolism, and the pathophysiological implications of these interactions for metabolic health.
Download or read book The Circadian Clock written by Urs Albrecht and published by Springer Science & Business Media. This book was released on 2010-01-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Download or read book Human Circadian Physiology written by Charles A. Czeisler and published by . This book was released on 1978 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Hypothalamic Pituitary Adrenal Axis in Health and Disease written by Eliza B. Geer and published by Springer. This book was released on 2016-12-01 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
Download or read book Biological Rhythms and Their Central Mechanism written by Masami Suda and published by North-Holland. This book was released on 1979 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Depression written by John F. Cryan and published by Karger Medical and Scientific Publishers. This book was released on 2010-01-01 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: What's new in antidepressant research? Despite the availability of antidepressants for over 40 years, a substantial proportion of depressed patients do not respond adequately to treatment. Failure to respond effectively to treatment contributes to physical ill-health and psychiatric morbidity, often resulting in premature death of the depressed patient. The purpose of this volume is to consider the possible reasons for the limitations of the currently available antidepressants, to examine the advances in our understanding of the psychopathology of depression and how such knowledge may assist in the discovery of new methods of treatment. Leading international experts in this field discuss the possible underlying reasons for depression and limitations of current antidepressants. Opportunities for novel therapeutic approaches to dysfunctional circadian rhythms and mood disorders as well as current status and future perspectives for optimizing antidepressant management of depression are reviewed. This publication illustrates the breadth of the latest research and is valuable reading for psychiatrists, neuroscientists and pharmacologists.
Download or read book Circadian Physiology written by Roberto Refinetti PhD. and published by CRC Press. This book was released on 2016-04-19 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the first edition of the critically acclaimed and highly popular Circadian Physiologyoffered a concise but rigorous review of basic and applied research on circadian rhythms, this newest edition provides educators with the primary textbook they need to support a course on this cutting-edge topic. Maintaining the same accessible multidi
Download or read book The Pancreatic Beta Cell written by and published by Academic Press. This book was released on 2014-02-20 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on the pancreatic beta cell. - Expertise of the contributors - Coverage of a vast array of subjects - In depth current information at the molecular to the clinical levels - Three-dimensional structures in color - Elaborate signaling pathways
Download or read book Circadian Clocks Role in Health and Disease written by Michelle L. Gumz and published by Springer. This book was released on 2016-02-29 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease.
Download or read book The Genetic Basis of Sleep and Sleep Disorders written by Paul Shaw and published by Cambridge University Press. This book was released on 2013-10-24 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive book on the subject, The Genetic Basis of Sleep and Sleep Disorders covers detailed reviews of the general principles of genetics and genetic techniques in the study of sleep and sleep disorders. The book contains sections on the genetics of circadian rhythms, of normal sleep and wake states and of sleep homeostasis. There are also sections discussing the role of genetics in the understanding of insomnias, hypersomnias including narcolepsy, parasomnias and sleep-related movement disorders. The final chapter highlights the use of gene therapy in sleep disorders. Written by genetic experts and sleep specialists from around the world, the book is up to date and geared specifically to the needs of both researchers and clinicians with an interest in sleep medicine. This book will be an invaluable resource for sleep specialists, neurologists, geneticists, psychiatrists and psychologists.
Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-09-13 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Download or read book The Rhythms Of Life written by Leon Kreitzman and published by Profile Books. This book was released on 2011-09-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.
Download or read book The Circadian Diabetes Code written by Satchin Panda, PhD and published by Rodale Books. This book was released on 2021-11-09 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Avoid, manage, and even reverse diabetes and prediabetes just by changing when—not what—you eat with this authoritative guide from the author of The Circadian Code. Today, one in ten Americans is diagnosed with type 2 diabetes, and one in three already has prediabetes. Prescription medications used to treat this chronic disease have unwanted side effects and at best, only manage the symptoms. What’s more, the restrictive dieting protocols used to manage diabetes are difficult to maintain over time. Yet the latest science shows that a simple approach that aligns your daily lifestyle—when you eat, sleep, and exercise—with your body’s inherent circadian rhythm can be just as effective. Best of all, following this program can enhance every other aspect of your health, from losing weight to boosting immunity. In The Circadian Diabetes Code, senior Salk Institute researcher and internationally-acclaimed author of The Circadian Code, Satchin Panda, Ph.D., shares his groundbreaking program. You will learn the best way to adopt intermittent fasting, the worldwide phenomenon that started in Dr. Panda’s lab, which has been used as an effective weight loss strategy for almost a decade. Now, you can use this same strategy to optimize your blood glucose response and naturally lower your risk for developing “the sinister friends of diabetes”: heart disease and obesity. The truth is, intermittent fasting is much easier that you think. You will learn how to: Identify your optimal eating zone Plan your meals according to your circadian rhythm Exercise at the right time to control blood glucose levels Get the best night’s sleep to reset your brain and body Optimally time medication, as needed And much more!
Download or read book Endocrine Rhythms written by Dorothy T. Krieger and published by . This book was released on 1979 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
