Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse and Neurotoxicity Annual of The NY Academy of Science written by Sayed Ali and published by Wiley-Blackwell. This book was released on 2006-08-23 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methamphetamine, MDMA, cocaine, PMA , GHB, and various solvents are the most widely abused drugs in Europe, the United States, Central America, South America, and Asia; and their use has dramatically increased over the last two decades. These drugs of abuse are known to cause neurotoxicity in several species, including not only rodents, dogs, and nonhuman primates, but also humans. The precise neurochemical mechanisms underlying this drug-induced neurotoxicity remain unclear. This volume explores this question, specifically addressing the following aspects: (1) the role of genomics and proteomics in drug-induced neurotoxicity, (2) drugs of abuse and medication development, (3) molecular biology and free radicals in drug-induced neurotoxicity, (4) substituted amphetamine-induced neurochemical changes and relationship to neurotoxicity, (5) drugs of abuse and imaging brain structure and function. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

Download or read book Current Status of Drug Dependence abuse Studies written by Syed F. Ali and published by . This book was released on 2004 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together basic and clinical investigators for the purpose of deepening our understanding of drugs of abuse and treatment of drug addiction. Methamphetamine, MDMA, PMA, and various solvents are the most widely abused drugs in the world; and their use has dramatically increased over the last two decades. These drugs of abuse are known to be neurotoxic in several species, including rodents, dogs, nonhuman primates, and humans. Nevertheless, the precise neurochemical mechanisms underlying this drug-induced neurotoxicity remain unclear. This volume will serve as a useful source of information not only for neurochemists, but also for investigators from many other disciplines.

Download or read book Drug Addiction written by Syed F. Ali and published by Wiley-Blackwell. This book was released on 2008-11-03 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together basic and clinical science to provide in-depth understanding and current knowledge concerning new conceptual insights into the CNS acting drugs and drugs of abuse and treatment of drug addiction. Methamphetamine, MDMA, PMA and different solvents are the most widely abused drugs in the Europe, United States, Central America, South America and Asian Countries and their use has dramatically increased over the last two decades. These drugs of abuse are known to cause neurotoxicity in several species including not only rodents, dogs and nonhuman primates, but also humans. However, precise neurochemical mechanisms underlying this drug-induced neurotoxicity remain unclear. This volume addresses the following: 1) Role of Genomics, Proteomics and Metabonomics in Drug-induced Neurotoxicity 2) Drugs of Abuse and Medication Development 3) Molecular Biology and Free Radicals in Drugs of Abuse-induced neurotoxicity 4) Substituted Amphetamines-induced Neurochemical Changes and Relationship to Neurotoxicity 5) Drug of Abuse and Imaging Brain Structure and Function 6) GHB/Volatile Solvent/Inhalant Neurotoxicity NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 1996 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text seeks to enhance our current knowledge and conceptual insights into drugs acting on the CNS and drugs of abuse. Cocaine, methamphetamine, and MDMA - known to be neurotoxic in several species, including rodents, dogs, and nonhuman primates - are the most widely abused drugs in the US, Europe, and Asia. The volume discusses cocaine addiction and neurochemical mechanisms of ibogaine and cocaine, and amphetamine-induced neurochemical changes and relationship to neurotoxicity.

Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse II written by Syed F. Ali and published by . This book was released on 2002 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers in this volume examine the cellular and molecular mechanisms of drugs of abuse as well as the neurochemical actions during drug abuse, including the processes of neuroprotection, neurodegeneration, and neuroadaptation. Certain papers present research on the neurotoxic actions and effects of substituted amphetamaines and MDMA. Other papers present studies on the molecular and cellular effects of chronic cocaine, heroin and opiate use. Also included are papers that examine the new technologies available for imaging brain structure and function before, during and after addiction. Recommendations for future research avenues and treatment methodologies are included.

Download or read book Molecular mechanisms of substance abuse and its neurotoxicity written by Jie Yan and published by Frontiers Media SA. This book was released on 2023-01-13 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurotoxicity of Drugs of Abuse written by and published by Academic Press. This book was released on 2022-10-07 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotoxicity of Drugs of Abuse, Volume Eight provides carefully crafted reviews on the disruptive impact of drugs of abuse on the central nervous system. The neurotoxicity potential of several agents including marijuana, fentanyl, and ketamine are carefully reviewed, and their short-term and chronic effects are categorized. Pharmacokinetic profiles as well as mechanisms of action for these and other drugs of abuse such as alcohol and nicotine are also evaluated. The implications of short and long-term abuse for agents such as PCP are also characterized. The reader will come away with a fuller understanding of the adverse effects of drugs of abuse on the nervous system. Describes in detail the characteristics of drugs of abuse that produce neurotoxicity Summarizes both the short and long-term adverse effects of drugs of abuse on the nervous system Describes potential mechanisms of action of centrally acting drugs of abuse

Download or read book Neurochemistry of Drugs of Abuse written by Syed F. Ali and published by New York Academy of Sciences. This book was released on 2000-06-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although a tremendous body of data has been gathered on the neurochemical changes engendered by exposure to drugs of abuse, the cellular mechanisms responsible for the changes remains unclear. In The Neurochemistry of Drugs of Abuse Syed F. Ali and his co-authors examine the cellular and molecular mechanisms of drugs of abuse (such as cocaine and substituted amphetamines) as well as drugs that have been proposed for the treatment of drug addiction (such as ibogaine, phenyltropane, and phentermine-fenfluramine). Among the contributors, FDA researchers present the clinical aspect in the development of medications designed to treat drug addiction. Other chapters are devoted to the underlying mechanisms of drug addiction, such as gene expression/molecular mechanisms, medication development, free-radical induced neurotoxicity, and specific neuronal markers. Bringing together both clinical and basic scientists in a multidisciplinary and multinational forum, The Neurochemistry of Drugs of Abuse presents a significant exchange of ideas in this expanding field of research.

Download or read book The Neurochemistry of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 1998 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains 34 papers from a 1997 meeting of the International Society for Neurochemistry and the American Society for Neurochemistry, convened in Hamilton, Bermuda, clarifying cellular and molecular mechanisms of abused drugs and of pharmacotherapies for drug addition. Papers are organized in sections on gene expression and molecular mechanisms of drug addiction, drugs of abuse and medication development (cocaine and ibogaine), the role of free radicals in drug- induced neurotoxicity, specific neuronal markers in substituted amphetamine-induced toxicity, and prenatal exposure and outcome. Annotation copyrighted by Book News, Inc., Portland, OR

Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 1995 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cellular and Molecular Mechanism of Drugs of Abuse and Neurotoxicity written by Syed Ali and published by . This book was released on 2006 with total page 676 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse written by and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neurobiological Mechanisms of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing reviewed versions of papers presented at the satellite meeting of the 17th biennial meeting of the International Society for Neurochemistry and the European Society for Neurochemistry held in August 1999, this volume explores the cellular and molecular mechanisms of drugs of abuse, such a

Download or read book Cellular and Molecular Mechanisms of Drugs of Abuse written by Syed F. Ali and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Download or read book Handbook of Substance Abuse written by Ralph E. Tarter and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of the literature pertaining to the neurobehavioral pharmacology of abusable drugs, this is the only book to survey each of the eleven classes of addictive drugs from the perspectives of neurological, behavioral, and clinical pharmacology. Designed to serve as a companion text to the DSM-IV manual, the Handbook provides comprehensive information about each drug and drug class having abuse potential with respect to their pharmaceutical mechanisms and actions.