Download or read book Cell mediated Immunity in Malaria written by Scientific Working Group on the Immunology of Malaria. Meeting and published by . This book was released on 1984 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigation of Cell Mediated Immunity to Malaria written by Yawalak Panpisutchai and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Download or read book Cell mediated immunity in malaria written by and published by . This book was released on 1984 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunology of Malaria written by World Health Organization. Scientific Group on the Immunology of Malaria and published by . This book was released on 1968 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book T cell mediated immune response in murine malaria differential effects of antigen specific Lyt T cell subsets in the recovery from Plasmodium yoelii infection in normal and T cell deficient mice written by Volker Brinkmann and published by . This book was released on 1984 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Malaria written by Mary M. Stevenson and published by CRC Press. This book was released on 1989-09-30 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to analyze and determine how a host responds to a blood stage malaria infection. It focuses on strategies for anti-malarial vaccination, genetic control of host resistance to malaria, and the contribution of the host genetic background to resistance or susceptibility to malaria. This book is an important reference work for anyone who studies the field of microbiology, immunology, or parasitology.
Download or read book Malaria written by Maria M. Mota and published by Springer. This book was released on 2017-01-12 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use. However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following: - Contributions by top research leaders in the field, - Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.
Download or read book Malaria Immunity Cell Mediated Studies written by Robert M. Coleman and published by . This book was released on 1975 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors were able to effect recovery and immunity to virulent murine malaria by red cell transfusion at crisis, during which time erythropoiesis did not keep pace with the rate of red cell destruction. Utilizing these immune animals as a source of spleen cells the authors have demonstrated by in vitro techniques the presence of two cell-mediated cytotoxic effector systems (macrophages and lymphocytes) against erythrocyte targets from malaria infected animals. Although parasitized erythrocytes appeared to be the most likely targets for cell-mediated destruction, decreased survival of transfused normal erythrocytes in malaria infected rats was observed. It has been further noted that splenic lymphocytes become specifically sensitized to malaria antigens during the course of virulent murine malaria infection, and have the ability to inhibit the migration of peritoneal macrophages in vitro (Coleman, et al., 1975a).
Download or read book T Cell Mediated Immunity in Resistance Against Blood Stages of Rodent Malaria written by Fiona Helen Amante and published by . This book was released on 1996 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Encyclopedia of Malaria written by and published by Springer. This book was released on 2018-07-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of Malaria represents a vast databank of information about the study of malaria. It provides an overview of the historical, rapid and significant developments that have occurred in malaria research, including the 2002 genome sequencing of Plasmodium falciparum and its mosquito vector, Anopheles gambiae. This work provides a concise source of up-to-date research findings in the form of definitions and essays and present comprehensive coverage of topics from history to findings to diagnosis and treatment, written by recognized malaria researchers with practical experience. It appeals to a diverse audience, including malaria researchers, teachers, investigators and public health professionals.
Download or read book HLA A2 Supertype Restricted Cell Mediated Immunity by Peripheral Blood Mononuclear Cells Derived from Malian Children with Severe Or Uncomplicated Plasmodium Falciparum Malaria and Healthy Controls written by and published by . This book was released on 2005 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding HLA-restricted adaptive host immunity to defined epitopes of malarial antigens may be required for the development of successful malaria vaccines. Fourteen epitopes of preerythrocytic malarial antigens known to mediate cytotoxic T-lymphocyte responses against target cells expressing HLA-A2-restricted epitopes were synthesized and pooled based on antigen: thrombospondin-related anonymous protein (TRAP), circumsporozoite protein (CSP), and export protein 1 (Exp-1) peptides. HLA-A2 supertype (*0201, *0202, *0205, *6802) peripheral blood mononuclear cells collected from 774 Malian children, aged 3 months to 14 years, with severe Plasmodium falciparum malaria matched to uncomplicated malaria or healthy controls were stimulated with the HLA-A2-restricted peptide pools. Significant gamma interferon production, determined by enzyme-linked immunospot assay to at least one of the three peptide pools, was observed in 24/58 (41%) of the severe malaria cases, 24/57 (42%) of the uncomplicated malaria cases, and 34/51 (67%) of the healthy controls. Significant lymphoproliferation to these peptides was observed in 12/44 (27%) of the severe malaria cases, 13/55 (24%) of the uncomplicated malaria cases, and 18/50 (36%) of the healthy controls. Responses to individual peptide pools were limited. These studies confirm the presence of adaptive cell-mediated immunity to preerythrocytic malaria antigens in volunteers from Mali and demonstrate that suballeles of the HLA-A2 supertype can effectively present antigenic epitopes. However, whether these immune responses to TRAP, CSP, and Exp-1 malarial proteins play a substantial role in protection remains a matter of controversy.
Download or read book Scientific Working Groups on Immunology of Malaria and on Applied Field Research in Malaria written by and published by . This book was released on 1988 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Mediated Immunity to Plasmodium Vivax Infection written by Kulachart Jangpatarapongsa and published by . This book was released on 2006 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rodent Malaria written by R. Killick-Kendrick and published by Elsevier. This book was released on 2012-12-02 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rodent Malaria reviews significant findings concerning malaria parasites of rodents, including their taxonomy, zoogeography, and evolution, along with life cycles and morphology; genetics and biochemistry; and concomitant infections. This volume is organized into eight chapters and begins by sketching out the history of the discovery of rodent as well as aspects of parasitology, immunology, and chemotherapy. These concepts are investigated two decades following Ignace Vincke's major discovery and Meir Yoeli's successful establishment of the method of cyclical transmission of the parasite. The following chapters focus on the taxonomy and systematics of the subgenus Vinckeia, with reference to the concepts of species and subspecies of animals and the degree to which they apply to malaria parasites, in particular to those of rodents. The discussion then shifts to how the rodent malaria parasites provide a unique insight into the subcellular organization of Plasmodium species, the use of rodent malaria as an experimental model to study immunological responses, and infectious agents that interact with malaria parasites. The book concludes with a chapter on malaria chemotherapy, with emphasis on the value of rodent malaria in antimalarial drug screening and the use of antimalarial drugs as biological probes. This book will be of interest to protozoologists and physicians as well as those from other disciplines including biochemistry, immunology, pharmacology, cell biology, and genetics.
Download or read book Cellular Immune Mechanisms in Malaria written by Richard P. MacDermott and published by . This book was released on 1981 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cell-mediated immune mechanisms responsible for human resistance to malaria need to be better understood. We have examined Thai adults naturally infected with malaria with regard to: (1) the percentages of T, B Null and Fc receptor bearing cells present during active infection; (2) the functional competence of peripheral blood mononuclear cells as judged by responsiveness to mitogens and cell surface antigens; (3) the ability of serum from infected patients to supress normal lymphocyte function; and (4) the incidence and nature of lymphocytotoxic antibodies in the serum of infected patients. In summary: (1) in adult Thai patients naturally infected with malaria, there ia a real loss of circulating T lymphocytes with no teal change in B or Fc receptor bearing lymphocytes and with no loss of lymphocyte function as judged by mitogenic and antigenic stimulation; (2) in the sera of patients infected with malaria, there are both functional suppressor capabilities and lymphocytotoxic antibodies; and (3) the role of serum immuno-regulatory capabilities in modulating the immune response of infected patients may be of importance in determining the chronicity of malaria infection as well as immunologically mediated complications.
