Download or read book Cell Mechanics During Phagocytosis Studied by Optical Tweezers Based Microscopy written by Holger Kress and published by Cuvillier Verlag. This book was released on 2006 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Adhesion of Cells Viruses and Nanoparticles written by Kevin Kendall and published by Springer Science & Business Media. This book was released on 2010-11-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Adhesion of Cells, Viruses and Nanoparticles" describes the adhesion of cells, viruses and nanoparticles starting from the basic principles of adhesion science, familiar to postgraduates, and leading on to recent research results. The underlying theory is that of van der Waals forces acting between cells and substrates, embodied in the molecules lying at the surfaces, together with the geometry and elasticity of the materials involved. The first part describes the fundamental background to adhesion principles, including the phenomenology, the important equations and the modeling ideas. Then the mechanisms of adhesion are explored in the second part, including the elastic deformations of spheres and the importance of the energy of adhesion as measured in various tests. It is demonstrated that adhesion of cells is statistical and depends on Brownian movement and on the complex multiple contacts that can form as cells move around. Then, detailed chapters on cell adhesion, contact of viruses and aggregation of nanoparticles follow in Part 3. Finally, the last chapter looks to the future understanding of cell adhesion and points out some interesting directions of research, development and treatment of diseases related to these phenomena. This book is an ideal resource for researchers on adhesion molecules, receptors, cell and tissue culturing, virus infection, toxicity of nanoparticles and bioreactor fouling. It can also be used to support undergraduate and Masters level teaching courses. "This is a fascinating book and it is an invaluable resource for understanding particle-particle/surface adhesion at micro- and nano- scales. I intend to keep one for my future reference and highly recommend it to my students." (Prof. Zhibing Zhang, School of Chemical Engineering, University of Birmingham, UK)

Download or read book Handbook of Antimicrobial Coatings written by Atul Tiwari and published by Elsevier. This book was released on 2017-09-22 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Antimicrobial Coatings is the first comprehensive work on the developments being made in the emerging field of antimicrobial coatings. Crucial aspects associated with coating research are presented in the form of individual chapters. Particular close attention has been given to essential aspects necessary to understand the properties of novel materials. The book introduces the reader to progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed as individual chapters. Chapters provide insight into the ongoing research, current trends and technical challenges in this rapidly progressing field. The covered topics were chosen so that they can be easily understood by new scholars as well as advanced learners. No book has been written on this topic thus far with so much crucial information for materials scientists, engineers and technologists. - Offers the first comprehensive work on developments being made in the emerging field of antimicrobial coatings - Features updates written by leading experts in the field of anti-microbial coatings - Includes discussions of coatings for novel materials - Provides various methods and techniques of synthesis and characterization detailed in individual chapters

Download or read book Nuts and Bolts Seven Small Inventions That Changed the World in a Big Way written by Roma Agrawal and published by W. W. Norton & Company. This book was released on 2023-11-07 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shortlisted for the 2023 Royal Society Science Book Prize A structural engineer examines the seven most basic building blocks of engineering that have shaped the modern world. Some of humanity’s mightiest engineering achievements are small in scale—and, without them, the complex machinery on which our modern world runs would not exist. In Nuts and Bolts, structural engineer Roma Agrawal examines seven of these extraordinary elements: the nail, the wheel, the spring, the magnet, the lens, the string, and the pump. Tracing the evolution from Egyptian nails to modern skyscrapers, and Neanderthal string to musical instruments, Agrawal shows us how even our most sophisticated items are built on the foundations of these ancient and fundamental breakthroughs. She explores an array of intricate technologies—dishwashers, spacesuits, microscopes, suspension bridges, breast pumps—making surprising connections, explaining how they work, and using her own hand-drawn illustrations to bring complex principles to life. Alongside deeply personal experiences, she recounts the stories of remarkable—and often uncredited—scientists, engineers, and innovators from all over the world, and explores the indelible impact these creators and their creations had on society. In preindustrial Britain, nails were so precious that their export to the colonies was banned—and women were among the most industrious nail makers. The washing machine displayed at an industrial fair in Chicago in 1898 was the only machine featured that was designed by a woman. The history of the wheel, meanwhile, starts with pottery, and takes us to India’s independence movement, where making clothes using a spinning wheel was an act of civil disobedience. Eye-opening and engaging, Nuts and Bolts reveals the hidden building blocks of our modern world, and shows how engineering has fundamentally changed the way we live.

Download or read book Optical Trapping Laser Tweezers and Nanosurgery Laser Scissors written by Michael W. Berns and published by Frontiers Media SA. This book was released on 2022-02-03 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms written by Xinyu Liu and published by Academic Press. This book was released on 2021-08-14 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies. - Comprehensive coverage of micro and nano-system technology and application to biophysical studies of cells and small organisms. - Highlights the most recent advances in cellular and organismal biophysics enabled by micro and nano systems. - Insightful outlook on future directions and trends in each chapter covering a sub-area of the book topic.

Download or read book Atomic Force Microscopy for Nanoscale Biophysics written by Mi Li and published by Elsevier. This book was released on 2023-02-15 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution. - Summarizes the recent progress of atomic force microscopy in biomedical applications - Presents the methods and skills of applying atomic force microscopy - Aids researchers in investigating the nanoscale biophysics of diverse biological systems

Download or read book Handbook of Biological Confocal Microscopy written by James Pawley and published by Springer Science & Business Media. This book was released on 2010-08-04 with total page 1014 pages. Available in PDF, EPUB and Kindle. Book excerpt: Once the second edition was safely off to the printer, the 110 larger world of micro-CT and micro-MRI and the smaller world authors breathed a sigh of relief and relaxed, secure in the belief revealed by the scanning and transmission electron microscopes. that they would “never have to do that again. ” That lasted for 10 To round out the story we even have a chapter on what PowerPoint years. When we ?nally awoke, it seemed that a lot had happened. does to the results, and the annotated bibliography has been In particular, people were trying to use the Handbook as a text- updated and extended. book even though it lacked the practical chapters needed. There As with the previous editions, the editor enjoyed a tremendous had been tremendous progress in lasers and ?ber-optics and in our amount of good will and cooperation from the 124 authors understanding of the mechanisms underlying photobleaching and involved. Both I, and the light microscopy community in general, phototoxicity. It was time for a new book. I contacted “the usual owe them all a great debt of gratitude. On a more personal note, I suspects” and almost all agreed as long as the deadline was still a would like to thank Kathy Lyons and her associates at Springer for year away.

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 1999 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: MBC online publishes papers that describe and interpret results of original research conserning the molecular aspects of cell structure and function.

Download or read book Advances in Bioengineering 2004 written by and published by American Society of Mechanical Engineers. This book was released on 2004 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.). and published by . This book was released on 2007 with total page 1164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Anais da Academia Brasileira de Ci ncias written by and published by . This book was released on 2007 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cell Biology and Translational Medicine Volume 20 written by Kursad Turksen and published by Springer Nature. This book was released on 2023-08-24 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 20th volume of a continuing series.

Download or read book Theoretical Biomechanics written by Vaclav Klika and published by BoD – Books on Demand. This book was released on 2011-11-25 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: During last couple of years there has been an increasing recognition that problems arising in biology or related to medicine really need a multidisciplinary approach. For this reason some special branches of both applied theoretical physics and mathematics have recently emerged such as biomechanics, mechanobiology, mathematical biology, biothermodynamics. This first section of the book, General notes on biomechanics and mechanobiology, comprises from theoretical contributions to Biomechanics often providing hypothesis or rationale for a given phenomenon that experiment or clinical study cannot provide. It deals with mechanical properties of living cells and tissues, mechanobiology of fracture healing or evolution of locomotor trends in extinct terrestrial giants. The second section, Biomechanical modelling, is devoted to the rapidly growing field of biomechanical models and modelling approaches to improve our understanding about processes in human body. The last section called Locomotion and joint biomechanics is a collection of works on description and analysis of human locomotion, joint stability and acting forces.

Download or read book Engineering the Interface Between Lipid Bilayers and Inorganic Materials written by Piyush Verma and published by Stanford University. This book was released on 2011 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding and engineering the interface between living matter and synthetic materials can enable technological advances in the areas of biosensors, therapeutics and diagnostics. One of the most crucial and commonly encountered class of such interfaces is the one between the cell membrane and various engineering materials and nanostructures. These interfaces can either be `large area' interfaces between the membrane and material surfaces or nanoscale `through thickness' cross-sectional interfaces that are formed as a synthetic material penetrates the membrane. This thesis describes contributions towards the understanding and/or development of each of these two kinds of interfaces. In the first two chapters, the focus is on synthetic membrane systems which provide a promising platform for biosensing applications. These are based on `large area' interfaces with engineering materials. One powerful approach consists of a synthetic lipid bilayer supported on an inorganic substrate. The non-covalent interactions between the lipids and the underlying substrate are of prime importance in these systems. Lipid spreading experiments, which measure the displacement, velocity, and roughness of the bilayer edge or the dynamic wetting line as it expands on the substrate, have proved useful in studying this interaction. However, previous spreading experiments have not observed any effects due to the inherent elasticity of the bilayer on expansion dynamics. To investigate this, dynamic expansion measurements of a phospholipid bilayer supported on substrates with different surface chemistry were performed. Remarkably different interface dynamics were observed on silica and chromium oxide surfaces. While the bilayer edge on silica monotonically roughened with expansion similar to other quenched noise 2-d systems, it showed a unique rough-smooth-rough interface transition on the chromium oxide substrate. This transition was found to be a result of the viscoelasticity of the lipid bilayer and could be modeled using a modified Edward-Wilkinson equation, which includes a spring-like term to account for the bilayer elasticity. These results demonstrate that the common lipid bilayer deposition technique of vesicle rupture generates supported lipid bilayers which are under compressive stress. This has important implications for biophysical studies performed on supported lipid bilayers and also for the stability of certain biosensing architectures like the pore spanning bilayer system. In the subsequent chapters, the emphasis is on developing a nanoscale `through thickness' interface between the cell membrane and synthetic nanostructures. The primary objective is to form an electrical interface with the interior of the cell for electrophysiological measurements. Such an interface is promising for various fundamental biophysical studies and also for applications such as high resolution neural prosthetics, on-chip electrically addressed artificial neuronal networks and chip based patchclamps. The main challenge in developing such interfaces is controlling the structure and properties of the junction between the device and cell membrane. Recent advances in nanoscale materials have enabled interactions at length scales natural to biology, thus providing an opportunity to control the structure of such junctions. By utilizing the design principles of transmembrane proteins that span the cell membrane, biomimetic metallic electrodes capable of penetrating the cell membrane can be developed. To elucidate the molecular structure of the electrode-membrane interface, coarse grained molecular dynamics (MD) simulations were carried out. These simulations revealed striking trends in interface structure for devices with different geometry and were used to optimize certain device parameters. Furthermore, energetics of the cell-device interaction were computed using thermodynamic integration and adiabatic switching to quantify the spontaneity of interaction. In the process, a unique methodology to compute the energetics of processes involving the interaction of nanostructured materials with soft matter structures was developed. In addition to these simulations, a physical model of cell deformation was developed to understand the mechanics of cell-device interaction. This was built on principles of continuum mechanics under a few simplifying assumptions. In addition to bringing down the parameter space for device design, this model explained a previously observed non-linear to linear transition in thin shell deformation experiments. Nanoscale `stealth' probed based on biomimetic design principles were fabricated using sophisticated microfabrication techniques. The electrical properties of the device were determined by performing cyclic voltammetry in a buffer solution with electrochemically active species. The formation of a well controlled junction between the post electrode and cell membrane was demonstrated by testing the device with red blood cells. A giga-ohm seal was observed to form spontaneously as the cell was brought close to the post, confirming intracellular access. The formation of giga-ohm seal is critical for patchclamping, a technique used extensively in the pharmaceutical industry. Together, MD simulations and cell deformation model provide a powerful approach to modify the device design depending upon the specific application. When coupled with the sophisticated yet flexible fabrication scheme developed for the device, the next generation of massively parallel and highly efficient interface between cells and electronics can be developed.

Download or read book Quantitative Imaging in Cell Biology written by and published by Academic Press. This book was released on 2014-06-25 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume, number 123, of Methods in Cell Biology looks at methods for quantitative imaging in cell biology. It covers both theoretical and practical aspects of using optical fluorescence microscopy and image analysis techniques for quantitative applications. The introductory chapters cover fundamental concepts and techniques important for obtaining accurate and precise quantitative data from imaging systems. These chapters address how choice of microscope, fluorophores, and digital detector impact the quality of quantitative data, and include step-by-step protocols for capturing and analyzing quantitative images. Common quantitative applications, including co-localization, ratiometric imaging, and counting molecules, are covered in detail. Practical chapters cover topics critical to getting the most out of your imaging system, from microscope maintenance to creating standardized samples for measuring resolution. Later chapters cover recent advances in quantitative imaging techniques, including super-resolution and light sheet microscopy. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material

Download or read book Light Robotics Structure mediated Nanobiophotonics written by Jesper Glückstad and published by Elsevier. This book was released on 2017-05-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Light Robotics – Structure-Mediated Nanobiophotonics covers the latest means of sculpting of both light and matter for achieving bioprobing and manipulation at the smallest scales. The synergy between photonics, nanotechnology and biotechnology spans the rapidly growing field of nanobiophotonics. Nanoscale resolutions enable optical scientists to assess ever more accurate information. However, scientific hypothesis testing demands tools, not only for observing nanoscopic phenomena, but also for reaching into and manipulating nanoscale constituents. Taking an application based focus, this book explores how nanophotonics can productively be used in both the biomedical and life sciences, allowing readers to clearly see how structure-mediated nanobiophotonics can be used to increase our engineering toolbox for biology at the smallest scales. This book will be of great use to researchers and scientists working in the fields of optics and photonics. It will also be of great value to those working in the field of biotechnology, showcasing how nanotechnology can help provide new, effective ways to solve biomedical problems. - Presents cutting-edge research on the principles, mechanisms, optical techniques, fabrication, modeling, devices and applications of nanobiophotonics - Brings together the diverse field of structure-mediated nanobiophotonics into one coherent volume - Showcases how nanophotonics can be used to create new, more effective micro- and nano-biodevices