Download or read book Cell Lineage and Embryo Patterning written by and published by Elsevier. This book was released on 2000-12-13 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus. Key Features * A number of important concepts are discussed, including: * How polarity is established during oogenesis * How germ cell determinants become organized in the establishment of the germ cell lineage * Different strategies used by organisms to establish the germ cell lineage * Similarities and differences between the mechanisms used in embryonic patterning * The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated * The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system * The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification

Download or read book Cell Lineage Specification and Patterning of the Embryo written by Laurence D. Etkin and published by . This book was released on 2001 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus. Key Features * A number of important concepts are discussed, including: * How polarity is established during oogenesis * How germ cell determinants become organized in the establishment of the germ cell lineage * Different strategies used by organisms to establish the germ cell lineage * Similarities and differences between the mechanisms used in embryonic patterning * The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated * The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system * The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification

Download or read book Cell Fate in Mammalian Development written by and published by Academic Press. This book was released on 2018-02-21 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Fate in Mammalian Development, Volume 128, the latest release in the Current Topics in Developmental Biology series, provides reviews on cell fate in mammalian development. Each chapter is written by an international board of authors, with this release including sections on the Specification of extra-embryonic lineages during mouse pre-implantation development, Cell polarity and fate specification, The circuitry that drives trophectoderm identity, Breaking symmetry and the dynamics of transcription factors directing cell fate specification, Mechanics and cell fate, How physical properties of cells change in development and their effect on cell fate decisions, and more. Provides the authority and expertise of leading contributors from an international board of authors Includes new sections on the specification of extra-embryonic lineages during mouse pre-implantation development, cell polarity and fate specification, the circuitry that drives trophectoderm identity, and more Presents the latest release in the Current Topics in Developmental Biology series

Download or read book Chromatin Regulation of Early Embryonic Lineage Specification written by Jason Knott and published by Springer. This book was released on 2017-11-23 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Five leaders in the field of mammalian preimplantation embryo development provide their own perspectives on key molecular and cellular processes that mediate lineage formation during the first week of life. The first cell-fate decision involves the formation of the pluripotent inner cell mass (ICM) and extraembryonic trophectoderm (TE). The second cell-fate choice encompasses the transformation of ICM into extraembryonic primitive endoderm (PE) and pluripotent epiblast. The processes, which occur during the period of preimplantation development, serve as the foundation for subsequent developmental events such as implantation, placentation, and gastrulation. The mechanisms that regulate them are complex and involve many different factors operating spatially and temporally over several days to modulate embryonic chromatin structure, impose cellular polarity, and direct distinct gene expression programs in the first cell lineages.

Download or read book From Egg to Embryo written by J. M. W. Slack and published by Cambridge University Press. This book was released on 1991-05-30 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last ten years have shown a dramatic revolution in our understanding of early animal development. This new edition of the successful first edition describes the result of this revolution and explains how the body plan of an embryo emerges from the newly fertilised egg. The book starts with a critical discussion of embryological concepts and explains in simple terms the mathematics of cell states, morphogen gradients and threshold responses. The experimental evidence on the mechanism of regional specification in Xenopus, molluscs, annelids, ascidians as well as Caenorhabditis, the mouse, the chick and Drosophila is then discussed. The whole chapter devoted to the exciting developments in Drosophila provides a clear guide to the subject, including a new table outlining the developmentally important genes. The emphasis throughout is on conceptual clarity and unity: bringing together the mathematical models, embryological experiments and molecular biology into a single, comprehensive coherent account.

Download or read book Signalling Pathways in Embryonic Development written by Juan J. Sanz-Ezquerro and published by Frontiers Media SA. This book was released on 2017-11-30 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches.

Download or read book Maternal Control of Development in Vertebrates written by Florence Louise Marlow and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References

Download or read book The Nematode Caenorhabditis Elegans written by William Barry Wood and published by . This book was released on 1988 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cell Lineage and Fate Determination written by Sally A. Moody and published by Academic Press. This book was released on 1999 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributors. -- Foreword. -- Sea Urchins and Ascidians: -- G.A. Wray, Introduction to Sea Urchins. -- R.A. Cameron and J.A. Coffman, Gene Expression and Early Cell Fate Specification in Embryos of the Purple Sea Urchin (Strongylocentrotus purpuratus). -- A.H. Wikramanayake and W.H. Klein, Otx, b-Catenin and the Specification of Ectodermal Cell Fates in the Sea Urchin Embryo. -- C.Y. Logan and D.R. McClay, Lineages that Give Rise to the Endoderm and the Mesoderm in the Sea Urchin Embryo. -- N. Satoh, Cell Fate Determination in the Ascidian Embryo. Nematode: -- W.B. Wood, Cell Lineages in Caenorhabditis elegans Development. -- B. Bowerman, The Maternal Control of Polarity and Patterning during Embryogenesis in the Nematode Caenorhabditis elegans. -- R.E. Ellis, Sex and Death in the Caenorhabditis elegans Germ Line. -- S.W. Emmons, Cell Fate Determination in Caenorhabditis elegans Ray Development. -- A. Hajnal, Cell Fate Determination and Signal Transduction During Caenorhabditis elegans ...

Download or read book Development written by V.E.A. Russo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of organisms have led to a greatly improved understanding of the genetic mechanisms underlying developmental processes, and the epigenetic and environmental influences on these processes. This second edition reviews these three levels and their relative importance to give the reader a clear picture of one of the most exciting areas of current biological research.

Download or read book Mouse Development written by Janet Rossant and published by Gulf Professional Publishing. This book was released on 2002-03 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production

Download or read book The Zebrafish Cellular and Developmental Biology Part B written by and published by Academic Press. This book was released on 2011-04-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Cell Biology, the second of two parts on the subject of zebrafish, provides a comprehensive compendium of laboratory protocols and reviews covering all the new methods developed since 1999.

Download or read book Biology and Pathology of Trophoblast written by Ashley Moffett and published by Cambridge University Press. This book was released on 2011-08-18 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 2006, this book provides an in-depth account of trophoblast: the tissue derived from the fertilised egg that nourishes and protects the developing fetus. The cells of the trophoblast have many unique qualities, and exhibit great variability across different species. It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo. These aspects are all fully covered as well as studies on why it is not rejected by the mother as 'foreign' tissue. Disorders of trophoblast during development also manifest themselves in several clinical conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia. From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is a lot to be learned about trophoblast, this volume provides a detailed summary of knowledge regarding the subject.

Download or read book Vertebrate Development written by Francisco Pelegri and published by Springer. This book was released on 2016-12-13 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of topics describing the earliest steps of fertilization, from egg activation and fertilization to the activation of the zygotic genome, in various studied vertebrate model systems. The contribution of maternal and paternal factors and their role in the early embryo as parental DNA becomes modified and embryonic genes become activated is fundamental to the initiation of embryogenesis in all animal systems. It can be argued that this is a unique developmental period, when information from the parents is compressed to direct the development of the body plan of the entire organism, a process of astounding simplicity, elegance and beauty. In addition to their fundamental scientific interest, many frontiers of biomedicine, such as reproductive biology, stem cells and reprogramming, and the understanding of intergenerational diseases, depend on advances in our knowledge of these early processes. Vertebrate Development: Maternal to Zygotic Control brings together chapters from experts in various disciplines describing the latest advances related to this important developmental transition. Each chapter is a synthesis of knowledge relevant to all vertebrates, with details on specific systems as well as comparisons between the various studied vertebrate models. The editorial expertise encompasses the fields of major vertebrate model systems (mammalian, amphibian and teleost) ensuring a balanced approach to various topics. This unique book—with its combination of in-depth and up-to-date basic research, inter-species comprehensiveness and emphasis on the very early stages of animal development—is essential for research scientists studying vertebrate development, as well as being a valuable resource for college educators teaching advanced courses in developmental biology.

Download or read book Xenopus Development written by Malgorzata Kloc and published by John Wiley & Sons. This book was released on 2014-06-03 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frogs from the genus Xenopus have long been used as model organisms in basic and biomedical research. These frogs have helped unlock key fundamental developmental and cellular processes that have led to important scientific breakthroughs and have had practical application in embryology, cancer research and regenerative medicine. Xenopus Development is a vital resource on the biology and development of these key model organisms, and will be a great tool to researchers using these frogs in various disciplines of biological science. Xenopus Development is divided into four sections, the first three highlight key processes in Xenopus development from embryo to metamophosis. These sections focus on the cellular processes, organogenesis and embryo development. The final section highlights novel techniques and approaches being used in Xenopus research. Providing thorough and detailed coverage, Xenopus Development, will be a timely and welcome volume for those working in cell and molecular biology, genetics, developmental biology and biomedical research. Provides broad overview of the developmental biology of both Xenopus laevis and Xenopus tropicalis Explores cellular to systems development in key biomedical model organisms Timely synthesis of the field of Xenopus biology Highlights key biomedical and basic biological findings unlocked by Xenopus

Download or read book The Vertebrate Organizer written by Horst Grunz and published by Springer Science & Business Media. This book was released on 2004-02-20 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The organizer area plays a central role in the formation of the embryonic axis and the central nervous system of all vertebrates including the human fetus. In The Vertebrate Organizer outstanding molecular development biologists and embryologists report their latest approaches in this fascinating research area using different vertebrate model organisms. The presented data are of central importance for the understanding of early human embryogenesis.

Download or read book Manipulating the Mouse Embryo written by Andras Nagy and published by Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press. This book was released on 2003 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides background information and detailed protocols for developing a mouse colony and using the animals in transgenic and gene-targeting experiments. The protocols list the animals, equipment, and reagents required and step-by-step procedures. Topics include in vitro culture of preimplantation embryos, surgical procedures, the production of chimeras, and the analysis of genome alterations. The third edition adds protocols for cloning mice, modifying embryonic stem cells, intracytoplasmic sperm injection, and cryopreservation of embryos.