Download or read book Carcinogenicity written by Kirk T. Kitchin and published by CRC Press. This book was released on 2021-12-17 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.
Download or read book Handbook of Carcinogen Testing written by Harry A. Milman and published by Taylor & Francis US. This book was released on 1985 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenicity written by Kirk T. Kitchin and published by CRC Press. This book was released on 1998-10-29 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers comprehensive coverage of currently available cancer predictors, the most recent research on carcinogenicity, and the design and interpretation of carcinogenicity experiments. Presents mouse, rat, and human carcinogenicity data for the liver, kidney, breast, cervix, prostate, hematopoietic system, colon, skin, urinary bladder, mouth, stomach, thyroid, and pancreas.
Download or read book Genotoxicity and Carcinogenicity Testing of Pharmaceuticals written by Michael J. Graziano and published by Springer. This book was released on 2015-11-02 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines, numerous case studies where follow-up studies were conducted to further investigate positive findings, and practical considerations for the use of alternative and emerging tests. With contributions from recognized experts in the pharmaceutical industry and health authorities, this volume presents a balanced view on the interpretation and application of genotoxicity and carcinogenicity regulatory guidances. Genotoxicity and Carcinogenicity Testing of Pharmaceuticals is a valuable resource for scientists, regulators, and consultants that are engaged in the conduct, reporting, and review of nonclinical studies. This book will also help academicians better understand and appreciate the complexity of the regulations and breadth of toxicology research that are necessary to support the development and marketing of new drugs.
Download or read book Pharmaceutical Medicine written by Adrian Kilcoyne and published by OUP Oxford. This book was released on 2013-05-23 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.
Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-03-12 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 451 Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of a long-term carcinogenicity study is to observe test animals for a major portion of their life span for the development of neoplastic lesions during or after exposure to various doses of a test substance by an appropriate route of ...
Download or read book Guidelines for the Testing of Chemicals for Carcinogenicity written by Great Britain. Committee on Carcinogenicity of Chemicals in Food, Consumer Products, and the Environment and published by . This book was released on 1982 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book America s War on carcinogens written by and published by . This book was released on 2005 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenicity Testing written by International Union against Cancer. Cancer Research Commission. Panel on Carcinogenicity and published by . This book was released on 1969 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Use of Small Fish Species in Carcinogenicity Testing written by and published by . This book was released on 1984 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 453 Combined Chronic Toxicity Carcinogenicity Studies written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...
Download or read book OECD Series on Testing and Assessment Guidance Document 116 on the Conduct and Design of Chronic Toxicity and Carcinogenicity Studies Supporting Test Guidelines 451 452 and 453 Second edition written by OECD and published by OECD Publishing. This book was released on 2014-09-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guidance provides additional information on the conduct of studies performed using Test Guidelines 451, 452 and Test Guideline 453.
Download or read book Carcinogenicity Testing written by International Union against Cancer. Panel on Carcinogenicity and published by . This book was released on 1969 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenicity Testing written by Anthony D. Dayan and published by . This book was released on 1978 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genotoxicity and Carcinogenicity Testing of Pharmaceuticals written by Michael J. Graziano and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines, numerous case studies where follow-up studies were conducted to further investigate positive findings, and practical considerations for the use of alternative and emerging tests. With contributions from recognized experts in the pharmaceutical industry and health authorities, this volume presents a balanced view on the interpretation and application of genotoxicity and carcinogenicity regulatory guidances. Genotoxicity and Carcinogenicity Testing of Pharmaceuticals is a valuable resource for scientists, regulators, and consultants that are engaged in the conduct, reporting, and review of nonclinical studies. This book will also help academicians better understand and appreciate the complexity of the regulations and breadth of toxicology research that are necessary to support the development and marketing of new drugs.
Download or read book Survey of Compounds which Have Been Tested for Carcinogenic Activity written by Jonathan L. Hartwell and published by . This book was released on 1998 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
