Download or read book Carcinogenic and Mutagenic Metal Compounds 2 written by Ernest Merian and published by CRC Press. This book was released on 1988 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenic and Mutagenic Metal Compounds 3 written by Ernest Merian and published by CRC Press. This book was released on 1991 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected papers from the Third Hans Wolfgang Nurnberg Memorial Workshop on Toxic Metal Compounds, Follinica, Italy, April 1988. The workshop discussed the gaps between chemistry and biology, and the topics covered include: the analytical chemistry and speciation of air particulates, water, sediments, soils, and of food and tissue; uptake by plants, mosses, and lichens, including biomonitoring techniques; and the uptake and biological effects of chromium, nickel, cadmium, and aluminum compounds. the papers were first published in issues of Toxicological and environmental chemistry and International journal of environmental analytical chemistry. Annotation copyrighted by Book News, Inc., Portland, OR
Download or read book Carcinogenic and Mutagenic Metal Compounds written by E. Merian and published by CRC Press. This book was released on 1985 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected papers presented at the Third Hans Wolfgang Nurnberg Memorial Workshop on Toxic Metal compounds held in Follinica, Italy in April 1988. This workship discussed the areas of research which link chemistry and biology, difining real problems for further research, and was attended by experts from different fields including analytical chemistry, speciation, environmental chemistry, biochemistry, short-term testing and risk assessment.
Download or read book Cytotoxic Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment written by N. Hadjiliadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental pollution is one of the main problems to confront humanity, with the heavy metals occupying a leading role among the most pernicious pollutants. The metals cause cancer and other sicknesses. Their cytotoxic, mutagenic and carcinogenic potentials are not fully understood, and any thorough investigation demands the combined efforts of scientists drawn from many different disciplines. But the effects of heavy metals are not all negative: some, like cis-DDP, and some ruthenium and tin complexes, have antitumour activity. The idea underlying the present work is therefore to present a multidisciplinary perspective on heavy metals in the environment, affording a better understanding of their action on human organisms and health, aiming to make them less polluting and more environmentally friendly.
Download or read book Carcinogenic and Mutagenic Metal Compounds Environmental and Analytical Chemistry and Biological Effects Volume 8 written by E Merian (Ed) and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenic and Mutagenic Metal Compounds 3 written by Ernest Merian and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Download or read book The Carcinogenicity of Metals written by Alan B. G. Lansdown and published by Royal Society of Chemistry. This book was released on 2013-10-31 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book re-evaluates epidemiological and occupational health studies, experimental studies in animals and in vitro experiments relating to the toxicity of 27 metal and metalloid elements for which evidence of carcinogenicity has been presented. Human carcinogenic risk is substantiated in relation to arsenic, beryllium, thorium, chromium, radioactive elements, probably lead, and some nickel and cobalt compounds, and respirable silica particles, but the carcinogenicity of iron, aluminium, titanium, tungsten, antimony, bismuth, mercury, precious metals, and certain related compounds in humans is unresolved. The toxicity and carcinogenicity of each element is specific but correlates poorly with its position in the Periodic Table. Carcinogenicity differs according to the valency of the ion and its ability to interact with and penetrate membranes in target cells and to bind, denature or induce mutations by genotoxic or epigenetic mechanisms. This important text comprehensively examines each of the elements providing detailed information on the carcinogenicity and toxicity and detailing the most up-to-date research in this area. The book is an essential tool for toxicologists, medicinal and biochemists, and environmental scientists working in both industry and academia.
Download or read book Molecular Mechanisms of Metal Toxicity and Carcinogenicity written by and published by . This book was released on 1994 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Effects of Heavy Metals written by E. C. Foulkes and published by CRC Press. This book was released on 1990-09-06 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: V.1. [without special title] -- v.2. Metal carcinogenesis.
Download or read book Environmental Carcinogens written by International Agency for Research on Cancer and published by . This book was released on 1986 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Carcinogenic and Mutagenic Metal Compounds 2 written by R. W. Frei and published by Gordon & Breach Science Pub. This book was released on 1987-11-01 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biological Effects of Heavy Metals written by E. C. Foulkes and published by CRC-Press. This book was released on 1990-09-06 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fascinating volume reviews general mechanisms of metal carcinogenesis. It illustrates this effect by detailed reference to some specific metals, including Cd, Co and Ni. The material illustrates the common threads running through the field of metal carcinogenesis. Leading investigators in the field present their understanding of metal carcinogenicity. Toxicologists, molecular biologists, and nutritionists will find this book interesting and informative.
Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Metal Carcinogenesis Testing written by Max Costa and published by Springer Science & Business Media. This book was released on 2008-02-07 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical descriptions of rapid and inexpensive in vitro assay methodology presently in use for the detection of potentially carci nogenic metals and their compounds. Mounting experimental evidence has suggested that a number of metals and their compounds are potentially carcinogenic to humans. Since humans are exposed to these potentially carcinogenic metals in industrial situations and through environmental pollution, it is essential that experimental protocols be available to identify the specific metal compounds that are potentially carcinogenic. This book affords a thorough description of the various carcinogenesis test systems available for metals, centering on those that are rapid, inexpensive, and most reliable. The principles are discussed at the level of human exposure, of animal studies, and of research in vitro. Additionally, the molecular mechanisms of metal-induced cancer are considered at each ofthese three levels.In large part, the emphasis rests on the use of in vitro, biochemical and bacterial studies, including tissue culture, because these methods are the basis of the rapid and inexpensive screening of potentially carcinogenic substances.
Download or read book Natural Metal Fiber and Macromolecular Carcinogens written by Yin-Tak Woo and published by Academic Press. This book was released on 2013-10-22 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIC: Natural, Metal, Fiber, and Macromolecular Carcinogens covers structure-carcinogenicity relationships of carcinogenic mycotoxins, carcinogenic substances generated by plants, carcinogenic metals and metalloids, and foreign-body carcinogens. The book discusses the metabolism and mechanism of carcinogenic action, physicochemical properties, other biological activities (principally mutagenicity and teratogenicity), modification of carcinogenic activity, formation and environmental significance. The text also describes the carcinogenic water-soluble high polymers and explores the intriguing problems of the carcinogenic effect of osmotic imbalance in tissue microenvironment, as well as of spontaneous malignant transformation occurring in cell cultures in vitro. Studies on tumor induction and carcinogenesis modification by nonviral nucleic acids, by nucleases, proteases, histones, and by antigenic stimulation as well as by antibodies are also considered. The book further tackles tumor-released factors as possible modifiers of carcinogenesis. The text will prove invaluable to chemists and people involved in cancer research.
Download or read book Metals and Genetics written by Bibudhendra Sarkar and published by Springer. This book was released on 2012-11-09 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past few years, major scientific discoveries have greatly contributed to our understanding of the relationship between metals and genetics. The fields which have contrib uted to this area range from Clinical Medicine and Genetics to Biochemistry and Chemistry. The aim of this book is to bring together investigators from these diverse fields to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume begins with a tribute to the late Karen Wetterhahn, an outstanding scien tist in the field, who will be sadly missed by her friends and colleagues because of her un timely death. The book has 28 chapters contributed by scientists who are internationally known for their expertise and outstanding research. The subject matters are divided into five major sections. The first section discusses genetic response to environmental expo sure to metals. Potentially devastating health crises have been reported in recent years from several parts of the world, which stem from environmental exposure to metals. In this section, authors report their findings on the effects and influence of metals in gene ex pression and their consequences to human health. The section on metal carcinogenesis and metal caused DNA damage, presents the latest advances in our knowledge of the molecu lar mechanisms of metal-induced mutagenesis and carcinogenesis. This topic is at the very heart of our understanding of how cancer may be caused by various metals.
