Download or read book Carcinogenesis Diagnosis and Molecular Targeted Treatment for Nasopharyngeal Carcinoma written by Shih-Shun Chen and published by BoD – Books on Demand. This book was released on 2012-02-15 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive treatise of the potential risk factors associated with NPC development, the tools employed in the diagnosis and detection of NPC, the concepts behind NPC patients who develop neuro-endocrine abnormalities and ear-related complications after radiotherapy and chemotherapy, the molecular mechanisms leading to NPC carcinogenesis, and the potential therapeutic molecular targets for NPC.
Download or read book Carcinogenesis Diagnosis and Molecular Targeted Treatment for Nasopharyngeal Carcinoma written by and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book An Evidence Based Approach to the Management of Nasopharyngeal Cancer written by Baharudin Abdullah and published by Academic Press. This book was released on 2020-05-22 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Evidence-Based Approach to the Management of Nasopharyngeal Cancer: From Basic Science to Clinical Presentation and Treatment provides a comprehensive overview with updated management procedures for nasopharyngeal carcinoma. Written by experts on the subject, it is organized in a simple yet comprehensive manner to aid in the understanding of this complex condition. The book discusses several topics related to NPC, including epidemiology, pathophysiology, risk factors and treatment (surgical and non-surgical). Additionally, it discusses key features of clinical presentation of NPC, recent advances and promising new therapies. This will be a valuable source for clinicians, graduate students, oncologists and several members of the biomedical field who are interested in understanding nasopharyngeal cancer in a practical and applicable way. Discusses current trends in surgery, including the use of endoscopy and robotic and navigation technology in the management of NPC Presents a summary with diagrams and workflows at the end of every chapter as a quick reference guide Encompasses colorful figures of pathology, clinical cases, endoscopic findings, surgical approaches, resection of tumors, brachytherapy and robotic and navigation technology so readers fully comprehend content
Download or read book HLA and MHC written by Michael J. Browning and published by Taylor & Francis. This book was released on 1996 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a review of the major histocompatibility complex (MHC), and the role it plays in the immune response and in disease. The emphasis throughout is on the human MHC, but relevant animal studies are inclded to give a comprehensive review of the subject.
Download or read book Head Neck Cancer Current Perspectives Advances and Challenges written by James A. Radosevich and published by Springer Science & Business Media. This book was released on 2013-05-24 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Download or read book Critical Issues in Head and Neck Oncology written by Jan B. Vermorken and published by Springer Nature. This book was released on 2023-03-27 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.
Download or read book Pharynx written by Xiaoying Zhou and published by BoD – Books on Demand. This book was released on 2021-09-08 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharynx - Diagnosis and Treatment provides scientific views from international experts on the latest studies and consensus in pharynx diseases, in particular pharyngeal tumors, including oropharyngeal carcinoma, nasopharyngeal carcinoma, hypopharyngeal carcinoma, and others. The book also addresses non-tumoral pharyngeal diseases such as nasopharyngeal angiofibroma and obstructive sleep apnea. The chapters present guidelines and standards commonly used in clinics for the pharynx diseases mentioned, as well as new updates covering recent scientific findings and translational research on the approaches of diagnosis and treatment.
Download or read book Nasopharyngeal Carcinoma written by Anne Wm Lee and published by Academic Press. This book was released on 2019-05 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nasopharyngeal Carcinoma: From Aetiology to Clinical Practice discusses NPC from basic science, to clinical management through the perspective of members of the Centre for Nasopharyngeal Carcinoma Research in Hong Kong. It encompasses not only the most detailed information about multiple aspects of NPC, but also the modern day research model of scientist-clinician collaboration, focusing on bench-to-bedside approach. Basic science is covered, discussing genetics and genomics in NPC and its epidemiology and the role of Epstein-Barr Virus (EBV). Translational research is also covered, presenting topics such as animal models, plasma EBV DNA, molecular imaging and immunotherapy, amongst other topics. This book is a valuable source for cancer researchers, oncologists, medical oncologists and several members of the biomedical field who are interested in learning more about NPC management from both clinical and research perspectives. Written by members of the Centre for Nasopharyngeal Carcinoma Research Extensively covers various aspects of NPC, including basic science and the clinical advances of both scientists and clinicians Discusses the molecular information gained through laboratory studies to stimulate research on new treatment strategies
Download or read book WHO Classification of Head and Neck Tumours written by Adel K. El-Naggar and published by IARC Who Classification of Tum. This book was released on 2017-01-23 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Classification of Head and Neck Tumours is the ninth volume in the 4th Edition of the WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies evaluating response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 135 authors from 35 countries, contains more than 600 color images and tables, and more than 2700 references. This book is in the series commonly referred to as the "Blue Book" series.
Download or read book Recent Advances in Cancer Research and Therapy written by Xin-Yuan Liu and published by Elsevier. This book was released on 2012-05-18 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.
Download or read book Heat Shock Proteins in Cancer written by Stuart K. Calderwood and published by Springer Science & Business Media. This book was released on 2007-09-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Download or read book Anterior Skull Base Tumors written by P. Nicolai and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.
Download or read book Molecular Diagnosis and Targeting for Thoracic and Gastrointestinal Malignancy written by Yutaka Shimada and published by Springer. This book was released on 2017-11-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs. In addition, it discusses the role of molecular diagnosis and targeted therapy in the course of surgical treatment. Recent, rapid advances in molecular biology have shed new light on the mechanisms of cancer progression, and molecularly targeted drugs have been used to treat a variety of malignant diseases. For the diagnosis and precise treatment of cancer, analysis of the molecular background of the tumor is indispensable. However, there are both tumor-specific and comprehensive mechanisms involved in these processes. Accordingly, a firm grasp of molecular diagnosis and targeted therapies for different tumors is vital for clinicians and basic researchers alike. This book provides essential information and the latest findings on molecular diagnosis and targeted therapy for thoracic and gastrointestinal malignancies. Though primarily intended for clinical and basic oncologists, it also offers a useful guide for clinicians who are interested in this field and are considering getting started in molecular diagnosis and targeted therapy.
Download or read book Textbook of Oral Cancer written by Saman Warnakulasuriya and published by Springer Nature. This book was released on 2020-02-22 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.
Download or read book Molecular Genetic Pathology written by Liang Cheng and published by Springer. This book was released on 2013-03-05 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
