Download or read book Candida albicans Cellular and Molecular Biology written by Rajendra Prasad and published by Springer. This book was released on 2017-01-31 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on Candida albicans and similar pathogens provides a timely overview of the groundbreaking discoveries made in the areas of drug resistance, host–pathogen interactions, virulence, host immune system modulation, etc., in the last two decades. This comprehensive 2nd Edition includes chapters on fungal infections, hyphal morphogenesis, molecular mechanisms of antifungal resistance, antifungal agents, multidrug transporters, virulence mechanisms in Candida albicans, host–pathogen interactions, the cell wall, fungal biofilms, lipids and antifungal resistance, signaling mechanisms and last but not the least host-immune responses. As such, it offers an ideal reference guide for mycologists, researchers, pharmacists, clinicians, and undergraduate students engaged or interested in fungal research. It will also benefit clinicians, who are required to keep abreast of the current state of research on antifungal drug resistance and antifungal development.
Download or read book Investigations in Yeast Functional Genomics and Molecular Biology written by Matthew Eckwahl and published by CRC Press. This book was released on 2014-02-24 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters. This book examines conserved pathways mediating cell cycle progression and cell polarity establishment. It includes examples of yeast, regulatory circuits, and feedback regulation, with emphasis on system-wide approaches. It also covers protein interaction networks and trait locus analysis and presents methods and challenges in comparative genomics analysis and evolutionary genetics.
Download or read book The Genetics of Candida written by Donald R. Kirsch and published by CRC Press. This book was released on 1990-05-29 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this volume is to provide a preliminary data base for Candida albicans plus serve as a reference for the genetic methods now available for the manipulation of several species in the genus Candida. This comprehensive review focuses primarily on C. albicans and includes reference data on the types and complementation status of mutations isolated in C. albicans, preliminary recombination mapping, chromosome analysis, physical measurements of DNA content and complexity, mitochondrial genome mapping, and analyses of restriction fragment length polymorphisms. It discusses a variety of genetic techniques in relation to current research questions aimed at virulence factors, dimorphism, and the potential use of Candida strains in biotechnology processes. This up-to-date publication is an indispensable resource for everyone who is involved with microbiology, genetics, and molecular and cellular biology.
Download or read book Biology of the Fungal Cell written by Richard J. Howard and published by Springer Science & Business Media. This book was released on 2007-06-30 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: What makes the fungal cell unique among eukaryotes and what features are shared? This volume addresses some of the most prominent and fascinating facets of questions as they pertain to the growth and development of both yeast and hyphal forms of fungi, beginning with subcellular components – then cell organization, polarity, growth, differentiation and beyond – to the cell biology of spores, biomechanics of invasive growth, plant pathogenesis, mycorrhizal symbiosis and colonial networks. Throughout, structural, molecular and ecological aspects are integrated to form a contemporary look at the biology of the fungal cell.
Download or read book Molecular Biology of Fungal Development written by Heinz D. Osiewacz and published by CRC Press. This book was released on 2002-05-07 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an overview of the fundamental aspects of molecular fungal development, this book covers different elements in the maturational and reproductive cycles of selected fungal taxa. Illustrating various molecular pathways in parasites and hosts, the book explores the development of interventional strategies for combating disease. Highlights in
Download or read book Candida Albicans written by Ronald L. Cihlar and published by Humana Press. This book was released on 2009-02-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have come as the result of newly available genome sequences of pathogens such as candida albicans and other model fungi. In Candida Albicans: Methods and Protocols, expert researchers explore these exciting new insights, focusing on the study of medically important fungi and Candida spp in particular. Chapters examine critical aspects of molecular methods, providing information on reporter gene assays, transformation, gene expression in vivo, and methods for large-scale gene disruption. At the same time, the work includes in-depth descriptions of disease models of candidiasis, facts about strain identification, and guidelines on the preparation of samples for proteomic investigations and tandem affinity purification. Composed in the highly successful "Methods in Molecular BiologyTM" series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting edge, Candida Albicans: Methods and Protocols is an invaluable source of methods for investigators in the exhilarating fields of medical and molecular mycology.
Download or read book Candida Albicans written by Doblin Sandai and published by BoD – Books on Demand. This book was released on 2019-04-24 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights modern techniques of research into Candida albicans, especially in terms of emerging and emerged pathogenic Candida species. It also looks at metabolic adaptation, resistance related to environmental stress and variety of nutrients, best performing plants that inhibit Candida's activities, interaction with other microbes, antifungal immunity mechanisms, and the posttherapeutic management of fungal infections. The book is a collection of very high impact research that includes a combination of biochemical, molecular biological, and medical microbiological innovative scientific techniques. It contains fascinating information that will help readers to explore and understand why C. albicans is different from other microbes. The authors describe this significant discovery using both bioinformatic and laboratory techniques and this uniqueness is the reason why C. albicans is a successful pathogenic yeast.
Download or read book Candida written by Christophe d'. Enfert and published by Caister Academic Press Limited. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Candida species are important human pathogens that are best known for causing opportunist infections in immunocompromised hosts (e.g. transplant patients, AIDS sufferers, cancer patients). Infections are difficult to treat and can be very serious. 30-40% of systemic infections result in death. The sequencing of the genome of C. albicans and those of several other medically-relevant Candida species has provided a major impetus for Candida comparative and functional genomic analyses. These have provided a fascinating insight into the molecular and cellular biology of these fungi, and these should pave the way for the development of more sensitive diagnostic strategies and novel antifungal therapies. In this timely book, international experts provide comprehensive and authoritative reviews of these important organisms. The topics covered include: genome dynamics of C. albicans; molecular, epidemiological, and population studies of C. albicans; the parasexual cycle in C. albicans; comparative genomics of the hemiascomycetes group and of different Candida species; databases and the challenges that their curators are facing; transcriptome analysis; proteomics; molecular evolution of the genetic code; stress responses; regulation of morphogenesis; cell wall biology; interaction with host cells; analysis of gene function; antifungal resistance mechanisms; and much more. This book is essential reading for all Candida genome and molecular biology researchers and a recommended text for scientists working on fungal genomics and molecular biology.
Download or read book Cellular and Molecular Biology of Filamentous Fungi written by Katherine Borkovich and published by American Society for Microbiology Press. This book was released on 2010-02-02 with total page 1959 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal starting point for any research study of filamentous fungi. • Incorporates the latest findings from such disciplines as physiology, taxonomy, genomics, molecular biology and cell biology. • Begins with an historical perspective, cell morphology and taxonomy, and moves on to such topics as cell growth, development, metabolism, and pathogenesis. • Presents the full range of the fungal kingdom and covers important topics as saprophytes, pathogens and endophytes. • Serves as a recommended text for graduate and undergraduate students.
Download or read book Candida Albicans written by Ronald L. Cihlar and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have come as the result of newly available genome sequences of pathogens such as candida albicans and other model fungi. In Candida Albicans: Methods and Protocols, expert researchers explore these exciting new insights, focusing on the study of medically important fungi and Candida spp in particular. Chapters examine critical aspects of molecular methods, providing information on reporter gene assays, transformation, gene expression in vivo, and methods for large-scale gene disruption. At the same time, the work includes in-depth descriptions of disease models of candidiasis, facts about strain identification, and guidelines on the preparation of samples for proteomic investigations and tandem affinity purification. Composed in the highly successful "Methods in Molecular BiologyTM" series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting edge, Candida Albicans: Methods and Protocols is an invaluable source of methods for investigators in the exhilarating fields of medical and molecular mycology.
Download or read book Dimorphic Fungi in Biology and Medicine written by D. Kerridge and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungal dimorphism is a topic that sounds inherently too rarified to attract more than a specialist audience. Yet some 230 individuals representing an eclectic mixture of interests, from basic science to medical practice, gathered in Churchill College, Cambridge in Semptember 1992 for a meeting devoted only to this subject. The symposium was the fourth in a series "Topics in Mycology" to be jointly organized by the Janssen Research Foundation and the International Society for Human and Animal Mycology. The participants enjoyed a rich and varied diet of oral presentations and poster displays in the field of fungal morphogenesis. This book sets down in print the material presented at the dimorphism symposium. We think that the high quality of these papers conveys very well the flavor of what was an excellent meeting. The selection of contributions in this volume covers very wide ground indeed. Chapters devoted to some non-pathogenic fungi are included, because the scientific basis of morphological development belongs to the fields of cellular and molecular biology: it does not recognize the boundary imposed by considerations of virulence of a fungus for a human host. Yet morphogenetic change in those fungi that do cause human disease frequently appears to be a component of the pathological process: many important pathogens change from a hyphal form in the external environment to a round form in infected tissues. This relationship between dimorphism and pathogenicity is the point of contact between pure biology and medicine.
Download or read book Human Pathogenic Fungi written by Derek J. Sullivan and published by Caister Academic Press Limited. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi cause a spectrum of diseases in humans, ranging from comparatively innocuous superficial skin diseases caused by dermatophytes to invasive life-threatening infections caused by species such as Candida albicans, or Cryptococcus neoformans. Due to the opportunistic nature of most invasive mycoses, fungal pathogenicity has proven difficult to define. However, the application of new genomic and other molecular techniques in recent years has revolutionized the field, revealing fascinating new insights into the mechanisms of fungal pathogenesis. In this book, a panel of high profile contributors critically review the most important research to provide a timely overview. The book is divided into two sections. The first six chapters review the transformative effect of applying state-of-the-art tools and innovative approaches to research, particularly in the area of comparative biology. The second section consists of eight chapters, each dedicated to the molecular and cellular biology of a major fungal pathogen of humans: Candida, Aspergillus, Cryptococcus, Dermatophytes, Histoplasma, Blastomyces, Pneumocystis, and Paracoccidoides. These chapters provide a timely snapshot of the current state of research. The book will be an essential reference for students, researchers, and clinicians with an interest in fungal pathogenesis. [Subject: Molecular Biology, Epidemiology, Life Science
Download or read book Medical Mycology written by Kevin Kavanagh and published by John Wiley & Sons. This book was released on 2006-08-14 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Mycology: Cellular and Molecular techniques is a clear and concise overview of the subject that details the techniques essential for ongoing research in the area. Drawing together contributions from both scientists and clinicians working in the field, the text will provide a valuable perspective on the applicability of specific techniques to patient care. A wide range of molecular, immunological and cytological techniques are discussed throughout, with the inclusion of protocol section in each chapter designed to provide both a background a up-to-date account of the applications of each procedure. Every technique is fully referenced and illustrations are provided where required to enhance student understanding. comprehensive introduction to the key techniques critical to the study of medical mycology clear explanation of how each technique is applied in the lab contributions from internationally recognised experts in the field outlines the background to many techniques required for the successful completion of a research project An invaluable reference for students of microbiology, biochemistry and molecular biology as well as postgraduates and researchers in the field of medical mycology looking for an up-to-date overview of the latest laboratory techniques.
Download or read book Pathogenic Yeasts written by Ruth Ashbee and published by Springer Science & Business Media. This book was released on 2009-10-27 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycological studies of yeasts are entering a new phase, with the sequencing of multiple fungal genomes informing our understanding of their ability to cause disease and interact with the host. At the same time, the ongoing use of traditional methods in many clinical mycology laboratories continues to provide information for the diagnosis and treatment of patients. This volume reviews various aspects of pathogenic yeasts and what is known about their molecular and cellular biology and virulence, in addition to looking at clinical and laboratory findings. As each chapter is written by a leading expert in the field, this book summarizes in one volume much of the latest research on several pathogenic yeasts, including Candida, Cryptococcus, Malassezia and yeasts of emerging importance. The importance of laboratory diagnosis, antifungal susceptibility testing, antifungal resistance and yeast diseases in animals are reviewed.
Download or read book The Yeast Role in Medical Applications written by Waleed Mohamed Hussain Abdulkhair and published by BoD – Books on Demand. This book was released on 2018-01-17 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology including medical applications depends on the yeast as biofermenter to produce many industrial products including pharmaceutical ones. Although yeasts are first known as useful microorganisms, some of them are identified as pathogens for plants, animals, and humans. Due to the simple cellular structure of the yeast among other microbial groups, it is used in the earliest investigations to determine the features of eukaryotic molecular biology, cell biology, and physiology. The economic income of some countries mainly depends on yeast for producing the economic products, such as France that depends on yeast for wine production. This book throws light on yeast and its important role in the medical applications.
Download or read book Candida Species written by Richard Calderone and published by Springer Nature. This book was released on 2022-08-25 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated volume explores Candida and candidiasis methods, useful to a wide variety of Candida scientists including those new to the field. Beginning with a section on the Candida genome, the book continues by covering techniques for antifungal discovery and studying resistance, pathogenesis and virulence, communities, as well as immunity. Biofilm protocols are also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Candida Species: Methods and Protocols, Second Edition serves as an ideal guide for researchers working to further our understanding of this family of infective fungi.
Download or read book Molecular and Cell Biology of Opportunistic Infections in AIDS written by S. Myint and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human immunodeficiency virus and AIDS have received much attention in the last decade. As the major cause of death in young adults, this concern is merited. AIDS has also ushered onto the clinical agenda a number of unusual and interesting pathogens. These have had considerably less attention than the virus itself, but are arguably as important. This book attempts to put into one volume a state of the art review of the basic biology of these opportunistic organisms. When compiling this book, the perceived difficulty was deciding how to restrict the number of chapters, as there is a large number of opportunistic organisms. It soon became clear, however, that the chapters would select themselves, as the work on many of these organisms was still in its infancy. We can be criticized for including Salmonella, which is not thought to be an opportunistic infection, and excluding Cryptococcus. Our defence is that the former has an interesting relationship with HIV and the latter is one of those organisms for which the basic biology is still in its early stages. The authors are all active researchers in their respective fields and we are grateful that they managed to review their subjects in the short turn-around time required for a book such as this not to be needlessly outdated on publication. We hope that, if nothing else, this book stimulates interest and more research on these agents: perhaps, in future editions, there will be much more to describe on their molecular biology.
