Download or read book Prostate Cancer Unmasked written by Ray M. Schilling, M.d. and published by Createspace Independent Publishing Platform. This book was released on 2017-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The FDA approved the PSA test in 1986 as a "monitor for treatment response and disease recurrence". Later in 1994 the FDA approved the PSA test as a screening tool for prostate cancer. But the question remained: what was the best treatment tool? I am reviewing 9 different treatment approaches in this book. They are all currently in use by different physicians. But they do not necessarily serve the patient best. Brachytherapy does not quite do it. It improves the cancer for a period of time, and after a few years it returns with a vengeance. The radical prostatectomy and the robotic prostatectomy have helped a significant amount of patients. But long-term studies show that there can be a recurrence rate of as much as 25 to 30%. In addition there are significant side effects like a killed sex life and involuntary dribbling of urine, if the bladder outlet was injured during the surgery. Quite often urologists recommend "active surveillance". This approach to prostate cancer means that a 71 to 75 year old prostate cancer sufferer is kept in suspense by the urologist. An initial rectal biopsy is done with a histology assessment where a Gleason score is analyzed. If this score is 6 or less, the cancer is presumed to be less aggressive and active surveillance is done. Another biopsy is done 1 year later and this could go on until the patient dies of a heart attack or a stroke. I think that prostate cancer should be treated early before metastases develop and the cancer gets out of control. There are other methods that actually can get rid of the prostate cancer, for instance cryoablation therapy following a mapping biopsy. In this latter method 60 biopsies are placed like a grid through the entire prostate gland to identify the exact location where prostate cancer has developed. This is done through the perineum (between the scrotum and the anal opening). Prostate cancer can often be multifocal: there may be two or three areas where prostate cancer is located. One month after the mapping procedure probes are introduced in the same way, through the perineum and the identified cancer lesions are treated with cryotherapy twice. I am explaining this in chapter 15 in more detail. According to Dr. Onik, an interventional radiologist in Ft. Lauderdale, active surveillance is something that should be abandoned. Instead the following treatment approach should be adopted. 1. A rising PSA or single PSA above 30 should trigger a referral for a mapping biopsy through the perineal approach under a general anesthetic. The treating physician can sterilize the area and perform biopsies in a sterile fashion, which prevents infection. This is a huge advantage above the standard transrectal approach, which can lead to infections like prostatitis and blood poisoning. 2. Based on the result of the mapping biopsy targeted ablation cryotherapy is performed one month later eradicating all the cancer foci determined through the mapping biopsy. 3. Follow-up PSA levels are obtained every three months for 2 years. If the PSA is less than 3.0, the patient is considered cured. If there is a rising PSA level point 1 and 2 above are repeated until a cure is achieved. Dr. Gary Onik published a 10-year follow-up study that had a 100% survival rate and a 94% cure rate in 70 men with prostate cancer. The reason for such good results is that attention is paid to detail, to the exact location of the cancer and that all cancer is completely eradicated. In my opinion this is the new blueprint of a common sense approach to prostate cancer. Read more details about this in chapter 15. Apart from the above mentioned treatment methods I reviewed external beam radiotherapy, laser ablation therapy and high-intensity focused ultrasound treatment. I noticed that the long-term cure rates over 10 years differ considerably from one treatment modality to the next. All of this is reviewed in detail in this book.
Download or read book Genius Unmasked written by Roberta Ness and published by Oxford University Press. This book was released on 2013-06-27 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shows how the most creative minds in science used tools that can help us improve our creative abilities. Geniuses are not omnipotent. They are just very skilled at employing the creativity toolbox highlighted in this book, including finding the right question, observation, analogy, changing point of view, dissection, reorganization, the power of groups, and frame shifting.
Download or read book Unmasked written by Emily Mendenhall and published by Vanderbilt University Press. This book was released on 2022-03-15 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unmasked is the story of what happened in Okoboji, a small Iowan tourist town, when a collective turn from the coronavirus to the economy occurred in the COVID summer of 2020. State political failures, local negotiations among political and public health leaders, and community (dis)belief about the virus resulted in Okoboji being declared a hotspot just before the Independence Day weekend, when an influx of half a million people visit the town. The story is both personal and political. Author Emily Mendenhall, an anthropologist at Georgetown University, grew up in Okoboji, and her family still lives there. As the events unfolded, Mendenhall was in Okoboji, where she spoke formally with over 100 people and observed a community that rejected public health guidance, revealing deep-seated mistrust in outsiders and strong commitments to local thinking. Unmasked is a fascinating and heartbreaking account of where people put their trust, and how isolationist popular beliefs can be in America's small communities. This book is the recipient of the 2022 Norman L. and Roselea J. Goldberg Prize from Vanderbilt University Press for the best book in the area of art or medicine.
Download or read book Zodiac Unmasked written by Robert Graysmith and published by Penguin. This book was released on 2007-01-02 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Graysmith reveals the true identity of Zodiac—America's most elusive serial killer. Between December 1968 and October 1969 a hooded serial killer called Zodiac terrorized San Francisco. Claiming responsibility for thirty-seven murders, he manipulated the media with warnings, dares, and bizarre cryptograms that baffled FBI code-breakers. Then as suddenly as the murders began, Zodiac disappeared into the Bay Area fog. After painstaking investigation and more than thirty years of research, Robert Graysmith finally exposes Zodiac’s true identity. With overwhelming evidence he reveals the twisted private life that led to the crimes, and provides startling theories as to why they stopped. America’s greatest unsolved mystery has finally been solved. INCLUDES PHOTOS AND A COMPLETE REPRODUCTION OF ZODIAC’S LETTERS
Download or read book Cancer Immunology and Immunotherapy written by Mansoor M. Amiji and published by Academic Press. This book was released on 2021-08-18 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Comprehensive treaty covering all aspects of immuno-oncology (IO) - Novel strategies for delivery of IO therapeutics and vaccines - Forecasting on the future of nanotechnology and drug delivery for IO
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2005 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cure Scientific Social and Organizational Requirements for the Specific Cure of Cancer written by and published by Arnold Glazier MD. This book was released on with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Batman Unmasked written by Will Brooker and published by Bloomsbury Publishing USA. This book was released on 2013-09-20 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the sixty years of his existence, Batman has encountered an impressive array of cultural icons and has gradually become one himself. This acclaimed book examines what Batman means and has meant to the various audiences, groups and communities who have tried to control and interpret him over the decades. Brooker reveals the struggles over Batman's meaning by shining a light on the cultural issues of the day that impacted on the development of the character. They include: patriotic propaganda of the Second World War; the accusation that Batman was corrupting the youth of America by appearing to promote a homosexual lifestyle to the fans of his comics; Batman becoming a camp, pop culture icon through the ABC TV series of the sixties; fans' interpretation of Batman in response to the comics and the Warner Bros. franchise of films.
Download or read book Cancer A Love Story written by Lauren Segal and published by Jaico Publishing House. This book was released on 2019-10-17 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Memoir of a four-time cancer survivor LAUREN SEGAL Cancer: A Love Story is the intimately searing memoir of a four-time cancer survivor. The book breathlessly tracks author Lauren Segal’s journey to come to terms with the untold challenges of facing the dreaded disease. Forced to face her needle phobia, the author leads the reader into her crumbling world as she confronts the terrors of treatment—from debilitating chemo to nuking radiation. Death is her uninvited companion. But in the midst of her lonely horror, in a quest for deeper meaning, Lauren discovers the unexpected gift of awareness of unanticipated opportunities that cancer presents—to confront her unmasked humanity—her fears, strengths and weaknesses. “I have come to understand that in the same way that the majestic lotus flower has its roots in murky waters, so too does the emergence of beauty in life sometimes depend on life’s darker events.” Lauren Segal currently works as a museum curator; her most recent project is curating and designing the new Johannesburg Holocaust and Genocide Centre. She heads up Trace, a research, design and exhibition company. Inspired by her own journey into self-discovery and healing, Lauren is currently studying part-time to become a psychoanalyst. “What a privilege to read this immensely inspirational and brave story. Lauren’s personality and energy leaps off the page – the mark of a natural and gifted writer.” —David Cohen, campaigns editor and chief feature writer, London Evening Standard
Download or read book Rheumatoid Arthritis Unmasked written by Kelly O'Neill Young and published by Ra Patient Insights, LLC. This book was released on 2017-10-31 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: What if no one confused rheumatoid disease with just arthritis?What if the world understood that people with rheumatoid disease (RD) are not hypochondriacs because they have so many health problems?What if all of the effects of the disease were treated ¿ not dismissed or ignored?Rheumatoid Arthritis Unmasked solves a primary problem for people living with rheumatoid arthritis (RA), the false impression that they are only fighting a type of arthritis.The facts in this book shatter the myth that too often confuses family, friends, employers, and most importantly medical personnel. In Rheumatoid Arthritis Unmasked you¿ll learn why the historical term rheumatoid disease (RD) describes not a type of arthritis, but a complex systemic disease with arthritis as only one of its symptoms. You¿ll understand how the fallacy of ¿arthritis¿ not only creates communication problems for people fighting RD, but also contributes to the devastating mortality gap by hindering needed clinical care and research that will lead to a cure. Rheumatoid Arthritis Unmasked exposes the true nature of RD revealed in medical research. For about a decade, Kelly O¿Neill Young has studied current and past academic research about RA, reading hundreds of journal articles for this book alone. But Kelly, widely known as the RA Warrior, has also gained a unique perspective by listening to the millions of people who visit her website and social network.¿Patients will learn key dangers to fight to avoid becoming a victim of the RD mortality gap.¿Clinicians will become better at diagnosing and treating RD.¿Friends and family will understand that their loved one with RD has a serious disease.¿Researchers will be more able to conduct impactful and successful investigations of RD.¿Health policy makers and medical payers will be able to properly categorize extra-articular RD.Rheumatoid Arthritis Unmasked is more than a gripping account of the dangers of RD - it is a path for change. This book equips all RA warriors to guide their own medical care and safeguard their health. This book will arm you with facts that will save lives.
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Download or read book Combinational Immunotherapy of Cancer Novel Targets Mechanisms and Strategies written by Xuyao Zhang and published by Frontiers Media SA. This book was released on 2024-01-15 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer immunotherapy, including immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has revolutionized the paradigm in cancer treatment. However, the clinical outcome of immunotherapy varies considerably among patients and only a minority of patients achieve long-term clinical benefits. This is largely attributed to the fact that existing cancer immunotherapies, which concentrate on several classical targets (CTAL-4, PD-1/PD-L1, etc.) and limited types of immune cell populations (T cells), are insufficient to cope with the complexity of highly heterogeneous tumor microenvironment (TME). This calls for more efforts to not only expand our toolbox for manipulating anticancer immunity but also diversify our combinational strategies. To this end, it is urgent to deeper our understanding of cancer immunotherapy by using both experimental and computational methodologies from multi-scale perspectives: 1) novel targets from either tumor cells or non-tumor cells within TME (e.g., tumor intrinsic resistance drivers, new immune checkpoints, neoantigens), 2) in-depth characterization of more immune cell populations (e.g., macrophages, Tregs, B cells) and their interactions and dynamics within TME, 3) landscape of actionable targets in patient populations for combination design. These efforts will open the avenue of rational design of combinational immunotherapies, allowing researchers and clinicians to design novel targeting therapeutics or to optimally orchestrate combinatory strategies aiming to surmount resistance mechanisms and improve clinical outcomes.
Download or read book Aspects of Cancer Research written by and published by . This book was released on 1979 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Physiopathology of Cancer written by Freddy Homburger and published by . This book was released on 1953 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Cancer Genetics written by Fred Bunz and published by Springer Science & Business Media. This book was released on 2008-01-14 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. Focused on the most highly representative genes that underlie the most common cancers, the book is aimed at advanced undergraduates who have completed introductory courses in genetics, biology and biochemistry, medical students, and house medical house staff preparing for board examinations. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand.
Download or read book Evolving Psychological and Educational Perspectives on Cyber Behavior written by Zheng, Robert and published by IGI Global. This book was released on 2012-07-31 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book identifies learners' online behavior based on the theories in human psychology, defines online education phenomena as explained by the social and cognitive learning theories and principles, and interprets the complexity of cyber learning"--Provided by publisher.
