Download or read book Cancer Immunotherapy Principles and Practice Second Edition written by Lisa H. Butterfield, PhD and published by Springer Publishing Company. This book was released on 2021-08-25 with total page 1339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs

Download or read book Cancer Immunotherapy Principles and Practice written by Lisa H. Butterfield, PhD and published by Springer Publishing Company. This book was released on 2017-06-28 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Immunotherapy Principles and Practice, from the Society of Immunotherapy of Cancer (SITC), is the authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease. Featuring five sections and over 50 chapters covering the Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy, this book covers all major topics that have shaped the development of immunotherapy and propelled it to its current place at the forefront of cancer treatment innovation. This volume is a comprehensive resource for oncologists and fellows, immunologists, cancer researchers, and related practitioners seeking understanding of the basic science and clinical applications of cancer immunotherapy. As well as presenting the evidence for immune-based cancer treatment, it positions immunotherapy in the context of other available cancer treatments and provides data on response rates, risks, and toxicities across a variety of diseases. Filled with detailed tables, and instructive illustrations, as well as key points for quick reference, Cancer Immunotherapy Principles and Practice simplifies a challenging and dynamic subject. Key Features: Clearly summarizes the basic principles and research supporting cancer immunotherapy clinical translation Contains expert guidance and treatment strategies for all immunotherapy classes and agents, including cell-based therapies, monoclonal antibodies, cytokine therapies, checkpoint inhibitors, oncolytic viruses, adjuvant approaches, and treatment combinations Includes expert perspectives from leading authorities in the field Provides information on all FDA-approved immunotherapies, including clinical management and outcome data Discusses clinical aspects of immunotherapy for individual cancer types, including melanoma and other skin cancers, lung cancers, gynecologic cancers, gastrointestinal cancers, hematologic cancers, genitourinary cancers, head and neck cancers, sarcomas, brain and other CNS cancers, breast cancer, and pediatric malignancies. Explains regulatory aspects behind the development and approval of immunotherapy drugs Includes Online Access to the Digital Book

Download or read book Cancer Immunotherapy in Clinical Practice written by Michael M. Boyiadzis and published by McGraw Hill Professional. This book was released on 2021-05-22 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: A top-to-bottom overview of cancer immunotherapy–from basic science to clinical application The rapidly evolving field of immunotherapy is thoroughly and expertly covered in this cutting-edge text. Written by a world-renowned author team, this innovative resource provides readers with a solid grasp of the fundamental principles of basic immunology so they can better understand the medical uses of immunotherapy. The book then advances to practical application and toxicity management. Presented in a concise, templated, and easy-to-read format, Cancer Immunotherapy is the single-best resource for readers to familiarize themselves with the medical use of immunotherapy. The book includes an entire section on eighteen individual cancer types (brain, breast, etc.) with listings of approved drugs, information on each drug, and discussion of emerging therapies for each of the cancers. • Groundbreaking in that it is the first cancer immunology book to combine the basic science with actual clinical application • Includes the latest guidelines for immunotherapy, cancer immunotherapy, and toxicity management • Valuable opening section includes discussion of introduction to immunotherapy, components of the immune system, vaccines, the immune system in cancer, and more

Download or read book Veterinary Immunology written by Michael J. Day and published by CRC Press. This book was released on 2014-06-23 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Immunology: Principles and Practice has become the adopted text in numerous veterinary schools throughout the world. Widely updated with advances in knowledge since 2011, this second edition reflects the rapid development in the field. The new edition presents expanded information on commonly used diagnostic test procedures and discusses

Download or read book Cancer Rehabilitation written by Michael O'Dell, MD and published by Demos Medical Publishing. This book was released on 2009-04-22 with total page 1130 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Doody's Core Title 2012 This new comprehensive reference provides a state-of-the-art overview of the principles of cancer care and best practices for restoring function and quality of life to cancer survivors. Authored by some of the world« leading cancer rehabilitation experts and oncology specialists, the principles section provides primer level discussions of the various cancer types and their assessment and management. The practice section thoroughly explores the identification, evaluation, and treatment of specific impairments and disabilities that result from cancer and the treatment of cancer.This groundbreaking volume enables the entire medical team to provide superior care that results in a better quality of life for cancer survivors. Features include: Multi-specialty editorship and authorship from physiatry, oncology, physical therapy, occupational therapy,and related disciplines. Focus on therapeutic management of cancer-related impairments and complications. In-depth treatment of the medical, neurologic, musculoskeletal, and general rehabilitation issues specific to this patient population.

Download or read book Guide to Immunotherapy written by Suzanne L. Walker and published by . This book was released on 2018-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Devita Hellman and Rosenberg s Cancer written by Govindan and published by Lippincott Williams & Wilkins. This book was released on 2012 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on: DeVita, Hellman, and Rosenberg's cancer / editors, Vincent T. DeVita Jr., Theodore S. Lawrence, Steven A. Rosenberg. 9th ed. c2011.

Download or read book Lung Cancer written by David J. Stewart and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.

Download or read book Immuno Oncology written by Thomas Ichim and published by Createspace Independent Publishing Platform. This book was released on 2015-05-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system offers the possibility of treating cancer and its metastasis without the toxicities of chemotherapy. Unfortunately, despite recent medical advances, overall survival of patients is still relatively dismal. Advances such development of Provenge, which is the first widely accepted immunotherapy of cancer have attracted media attention and interest, however survival advantage was only 3 months in double blind trials. In this book we take a multi-disciplinary approach to analyzing in a highly referenced and technical manner the various cellular, biochemical and immunological changes that occur in cancer patients. By categorizing what cancer does to the body, and how the body tries to fight the cancer, an overall picture is painted of various interventions and combination interventions that can be tried in order to maximize probability of patient improvement. Various conventional and unconventional approaches to cancer are described in this volume, including macrophage activation therapy, oxidative medicine, lymphokine activated killers, and non-specific immune stimulants. Significant effort was made by the authors to detail how various components of the immune system collaborate in the recognition of cancer cells, how cancer cells avoid immune attack, and means of derepressing immunity using chemical, cellular, and genetic approaches. Specific tumor immune evasion mechanisms that are described include: a) the tryptophan-catabolizing enzyme indolamine 2,3 deoxygenase (IDO), which selectively induces suppression of cytotoxic T cells through anergy, apoptosis, and T regulatory cell generation; b) IL-10, a cytokine produced by tumor cells, as well as tumor-associated macrophages, which induces generation of T regulatory cells; c) cancer derived exosomes, which act as nanoparticle vesicles, that directly induce apoptosis of tumor-reactive T cells, as well as assist in formation of extracellular matrix that is receptive to tumor metastasis; d) soluble HLA-like molecules including MICA, which block the activation of natural killer cells, the cells that are capable of killing tumors which have downregulated antigen presentation; e) arginase, an enzyme produced by M2 macrophages, which produces an immune suppressive localized environment; and f) tumor lactic acid accumulation, which blocks cytotoxic activity of T cells, while at the same time allowing for survival of T regulatory cells, which in turn suppress the immune system. In addition to overviewing how cancer suppresses the immune system, discuss how the immune system suppresses cancer. Detailed descriptions are provided of immune modulators that have demonstrated clinical efficacy signals dating back from the days of Coley's toxins, all the way to the current immune checkpoint inhibitor trials. Specific areas of concentration include: a) cytokine induced killer cells; b) lymphokine activated killers; c) BCG; and d) cancer vaccines. We trust that the current volume will provide its readers not only with details of the immune-tumor interaction, but will also provide solid support for novel experimental approaches to cancer, including combination of T regulatory cell depleting chemotherapies with immunotherapy, as well as combinations of intravenous nutrients with immune stimulators.

Download or read book Principles and Practice of the Biologic Therapy of Cancer written by Steven A. Rosenberg and published by . This book was released on 2000 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference on the biologic therapy of cancer provides scientific and practical information to both researchers and clinicians involved in the development and application of new cancer treatments. Major sections of the book cover: cytokines; cell transfer therapy; monoclonal antibodies; cancer vaccines; gene therapy; and antiangiogenesis therapy. Each section begins with basic principles and preclinical studies, and proceeds to clinical applications. The clinical chapters present comprehensive analyses of clinical data, emphasizing the indications for treatment and the practical guidelines necessary to safely apply these new approaches.

Download or read book Mosby s Oncology Nursing Advisor E Book written by Susan Newton and published by Elsevier Health Sciences. This book was released on 2016-09-10 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get quick access to the most important information surrounding cancer and oncology nursing care with Mosby’s Oncology Nursing Advisor, 2nd Edition. Covering everything from the various types of cancer and cancer treatment options to patient education and nursing best-practices, this indispensable nursing guide is like getting seven books in one! Plus, its user-friendly layout and straightforward coverage make it ideal for use in any clinical setting. With 17 new chapters, updated evidence-based content throughout, and proven patient teaching handouts, this new edition offers the authoritative guidance you need to provide the best possible oncology nursing care. Detailed descriptions of over 50 major cancer types provide essential information on incidence, etiology and risk factors, signs and symptoms, diagnostic workup, histology, staging, treatment, prognosis, and prevention. Coverage of cancer management principles outlines a wide range of treatment and pharmacologic modalities, including surgery, chemotherapy, radiation therapy, hormonal therapy, immunotherapy, and complementary and alternative therapies. Symptom management guidelines offer in-depth coverage of pathophysiology, signs and symptoms, assessment tools, lab and diagnostic tests, differential diagnoses, interventions, patient education, follow up care, and resources for over 30 common symptoms associated with cancer and cancer treatments. Essential information on many oncologic emergencies and emergent issues prepares readers to respond quickly to structural, metabolic, and hematologic emergencies. Section on palliative care and end-of-life issues offers helpful guidelines for dealing with topics related to survivorship, palliative care, the final hours of the cancer patient, and loss, grief, and bereavement. NEW! Updated evidence-based content reflects the latest national and international quality standards regarding various cancer types, major drug and non-drug treatments, treatment protocols, and approaches to symptom management. NEW! Nursing Practice Considerations section incorporates information on communication, cultural considerations, ethical considerations, safe and quality care, evidence-based practice, patient navigation, and patient education. NEW! 17 new chapters cover topics including myelofibrosis, neuroendocrine cancers, tumor treating fields, oral adherence, clinical trials, epistaxis, hypersensitivity reactions, hypertension, hyperglycemia, nail changes, ocular and visual changes, rashes, survivorship, quality and safety, evidence-based practice, nurse navigation, and patient education. NEW! Expanded content on patient education keeps readers on top of best practices in this critical area. NEW! High-quality electronic patient teaching handouts are evidence-based and have been vetted by practicing nurses.

Download or read book Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice written by MiKaela M. Olsen and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Oncology nursing is a unique specialty that requires continuous learning to stay up to date on cancer pathophysiology, cutting-edge drugs, and the evidence-based management of cancer and cancer treatment-related toxicities. The Oncology Nursing Society's (ONS's) second edition of Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice provides nurses with the tools to understand how medications are used in cancer treatment, the effect of medication-related toxicities, and evidence-based recommendations to manage and treat these toxicities. This edition features many new cancer therapies approved since the 2019 publication. Each drug is categorized as chemotherapy, hormone, targeted, or immunotherapy agents. Extensive drug tables in the book provide nurses with tips for managing patients receiving these drugs. The expansion of oral antineoplastic therapies, alone or in combination with infusion therapy, requires that nurses review a patient's complete cancer treatment plan and consider the side effects, toxicities, and adherence to oral drugs to ensure patient tolerance and efficacy. This second edition has seen content expanded on the topic of genomics as we move forward in the world of personalized oncology. Health equity is approached with information discussing financial distress, cultural disparities, and health literacy. The latest guidelines and recommendations for treatment, symptom management, and survivorship have been integrated into this new text. This edition features a QR code, provided with the purchase of this book, to download quarterly drug updates. You will see new evidence related to many aspects of cancer nursing care incorporated into this edition, such as hypersensitivity response, safe handling of hazardous drugs, and more. The editors want to thank all of the contributors to this edition who worked tirelessly, despite a pandemic, to make this new edition a reality. This work builds on the knowledge of many generations of oncology nurses and has been used nationally and internationally to guide oncology nursing practice. We are proud to continue to serve oncology nurses worldwide with an essential resource to guide their practice"--

Download or read book Principles and Practice of Palliative Care and Support Oncology written by Ann Berger and published by Lippincott Williams & Wilkins. This book was released on 2021-03-01 with total page 1877 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only book on the market to cover palliative care for both adults and children, Pediatric and Adult Palliative Care and Support Oncology offers an easy-to-read, interdisciplinary approach to supportive oncology as well as end-of-life care. Ideal for oncologists, residents, fellows, nurse practitioners, and physician assistants, the fifth edition provides important updates for conventional topics while also featuring several brand new chapters. Covering everything from dermatologic toxicity of cancer treatment to running family meetings for setting goals of care, this unique title is a source of both help and inspiration to all those who care for patients with cancer.

Download or read book Oncology Clinical Trials written by Susan Halabi, PhD and published by Demos Medical Publishing. This book was released on 2009-12-22 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the marketplace, and expand the horizon of contemporary thinking about cancer biology. A poorly done trial does little to advance the field or guide clinical practice, consumes precious clinical and financial resources and challenges the validity of the ethical contract between investigators and the volunteers who willingly give their time and effort to benefit future patients. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives, Oncology Clinical Trials, provides a comprehensive guide for both early-career and senior oncology investigators into the successful design, conduct and analysis of an oncology clinical trial. Oncology Clinical Trials covers how to formulate a study question, selecting a study population, study design of Phase I, II, and III trials, toxicity monitoring, data analysis and reporting, use of genomics, cost-effectiveness analysis, systemic review and meta-analysis, and many other issues. Many examples of real-life flaws in clinical trials that have been reported in the literature are included throughout. The book discusses clinical trials from start to finish focusing on real-life examples in the development, design and analysis of clinical trials. Oncology Clinical Trials features: A systematic guide to all aspects of the design, conduct, analysis, and reporting of clinical trials in oncology Contributions from oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives Hot topics in oncology trials including multi-arm trials, meta-analysis and adaptive design, use of genomics, and cost-effectiveness analysis Real-life examples from reported clinical trials included throughout

Download or read book Cancer Chemotherapy Immunotherapy and Biotherapy written by Bruce Chabner and published by LWW. This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Thoroughly revised and reformatted, the sixth edition of Cancer Chemotherapy, Immunotherapy and Biotherapy reflects recent significant changes in cancer treatment. This newly streamlined edition contains full-color illustrations, more tables for quick reference, and new immunotherapy and molecular targeted therapy content that brings you fully up to date with the state of the art in all current cancer therapies. Provides thorough, comprehensive coverage of the scientific and clinical aspects of immunotherapy, biotherapy, and chemotherapy. Includes significantly expanded information on immunotherapy and molecular targeted therapy, as well as the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Features a new, full-color format, a newly streamlined presentation. and more tables and figures throughout for quick access to high-yield information. Explains the rationale for use of drugs in specific schedules and combinations and offers guidelines for dose adjustment in specific situations. Enhance Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Download or read book Breast Cancer Imaging written by Marie Tartar and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through a case-based approach, this book illustrates the best practices for all facets of breast cancer imaging - from screening of asymptomatic patients to cancer staging, identifying metastases, and assessing efficacy of treatment - in a succinct, practical source. Contributing authors from a wide range of subspecialties provide well-rounded guidance to meet the needs of today's multidisciplinary work environment. Presents multidisciplinary discussions on the advantages and/or limitations of all available modalities. Includes advice from leading experts on cross-sectional imaging, breast imaging, and PET/CT, with input from radiation oncology, medical oncology, and breast surgery, to span the complete spectrum of care from screening to diagnosis to treatment, reflecting today's team approach to patient care. Covers all imaging modalities to help you correlate disease presentations on mammography, CT, MR, US, and PET images. Offers a very practical, clinical, concise approach to the subject in a case-based format. Provides over 1,000 high-resolution images of disease appearance for comparison with the findings you encounter in your practice.

Download or read book Cancer Chemotherapy and Biotherapy written by Bruce A. Chabner and published by Lippincott Williams & Wilkins. This book was released on 2011-12-07 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.