Download or read book Cancer Chemotherapy and Biological Response Modifiers Annual written by Herbert Michael Pinedo and published by . This book was released on 1987 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its ninth year the Cancer Chemotherapy Annual series has been renamed, reformatted and expanded to include a section on biological response modifiers. It is, and will remain, the only medium for oncologists to keep pace with the many thousands of articles published in their field. The international board of some seventy contributors now also includes experts in biological therapeutics, who have evaluated their segment of the international medical literature. The editors, H.M. Pinedo and B.A. Chabner, have secured the assistance of D.L. Longo, who qualifies as the director of the Biological Response Modifiers Program of the National Cancer Institute in Frederick, MD, USA.
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by H. M. Pinedo and published by Elsevier Science & Technology. This book was released on 1994-01-01 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is part of a series of annuals that present critical reviews of the recent developments in the pharmacology of anti-cancer agents, the area of biologicals and the clinical management of the cancer patient.
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by and published by . This book was released on 1990 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by H. M. Pinedo and published by Elsevier Science Health Science Division. This book was released on 1997 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Chemotherapy and Biological Response Modifiers has provided its readers with a comprehensive, definitive annual review of the literature in the fields of cancer biology, pharmacology, treatment and management. Its contributors are internationally renowned figures in the field of oncology. This volume contains 30 chapters reviewing recent developments within specific subject areas of oncological research. Having this up to date information on hand will ensure that you are well informed, so you can stay at the forefront of your profession.
Download or read book Cancer Chemotherapy and Biological Response Modifiers Annual 20 written by Giuseppe Giaccone and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by Herbert M. Pinedo and published by . This book was released on 1988 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Chemotherapy and Biological Response Modifiers Annual 21 written by Giuseppe Giaccone and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemotherapy and Biological Response Modifiers written by H. M. Pinedo and published by Elsevier Science & Technology. This book was released on 1999 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hardbound. Cancer Chemotherapy and Biological Response Modifiers provides its readers with a comprehensive, definitive annual review of the literature in the fields of cancer biology, pharmacology, treatment and management. Its contributors are internationally renowned figures in the field of oncology. The contents of this new volume, Annual 18, will again review recent developments within these subject areas, ensuring that its readers are kept up-to-date with the latest information.
Download or read book Cancer Chemotherapy and Biological Response Modifiers written by Guiseppe Giaccone and published by Elsevier. This book was released on 2005-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 22nd Volume of CANCER CHEMOTHERAPY & BIOLOGICAL RESPONSE MODIFIERS continues in the tradition of providing a timely review of progress and achievements in clinical oncology. The emphasis of Annual 22 is on recent advances in the understanding of anti-cancer drugs, specific malignancies and biological response modifiers. The section on drugs includes new chapters on the clinical use of epidermal growth factor receptor pathways and on angiogenesis pathway inhibitors. These agents have moved rapidly from preclinical models to demonstrated clinical efficacy and are becoming part of comprehensive oncologic care. The section on tumours provides detailed updates on past year's advances in the understanding of risk, classification, staging and management of common malignancies. The section on biologics provides chapters on active immunotherapy through vaccines or cytokine administration, exciting perspectives on the modification of T cells to recognise tumours using tumour-reactive monoclonal antibody, and an important review detailing the effect of conventional cancer treatment on the patient's immune system. The special section within Annual 22 is devoted to recent advances in the understanding and treatment of melanoma. Special detail is included regarding advances in screening, prevention and predisposition for this increasingly frequent disease, in addition to chapters on surgical treatment and biologic response modifiers interventions. Chapters on the uses of interferon, and on other cytokines combined with chemotherapy, summarise how and when these approaches have proven to be useful. Four chapters then review separate classes of immunologic interventions for melanoma.
Download or read book Biological Response Modifiers written by National Cancer Institute (U.S.) Subcommittee on Biological Response Modifiers and published by . This book was released on 1983 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rationale of Biological Response Modifiers in Cancer Treatment written by Eiro Tsubura and published by Elsevier Science & Technology. This book was released on 1985 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combination Therapies written by E. Garaci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined. These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances in this area have also led to rethinking therapies against a range of autoimmune disorders and other diseases associated with immune and endocrine imbalances. BRMs currently are being applied clinically as both primary and adjunctive therapy to enhance the effectiveness of traditional treatments by maximizing their activities and to protect critical tissues against intolerable chemotherapeutic and radiation damage. Present constraints against the use of BRMs revolve around the nature of these substances in vivo, where many of their actions and the majority of their interactions and synergies remain to be elucidated. For example, as these molecules are thought to exert their effects locally, the systemic administration of lymphokines, cytokines and growth factors at doses adequate to produce a wanted anti-tumor effect in many instances is intolerably toxic. Efforts to overcome this formidable problem have led scientists to begin to explore the transfer of genes known to encode for these molecules into cells which otherwise inadequately elicit or produce anti-tumor or anti-infective responses.
Download or read book Biological Response Modifiers and Cancer Therapy written by J. W. Chiao and published by Marcel Dekker. This book was released on 1988 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Screening for Biological Response Modifiers Methods and Rationale written by James E. Talmadge and published by Springer. This book was released on 1985-04-30 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The observation in the 1950s that nitrogen mustard and other toxic chemicals could induce antitumor responses in patients with refractory lymphoma initiated a massive search for active chemotherapeutic agents. The initial observations stimulated a search for new chemotherapeutic agents which might have increased antitumor activity with less toxicity for normal tissues. To aid in the search for these new chemicals and to attempt to distinguish among the many toxic chemicals which might be candidates for clinical studies, the National Cancer Institute, the pharmaceutical industry, and the cancer research laboratories of most Western nations developed systems for "screening" drugs for antitumor activity. Perhaps the most extensive screening program was established by the National Cancer Institute (1). This screening program has evolved over the last two decades, an evolution which has been repeatedly reviewed (2-5). Various screening programs in use have examined over 500,000 compounds as potential anticancer agents. From these, there are now approximately forty anticancer drugs in clinical use. The utiliy of these compounds and their toxicities have been reviewed on many occasions. It is now apparent that more active and less toxic anticancer drugs are needed. It is also clear that the current screening programs are identifying compounds with similar levels of activity and with continuing moderate to severe toxicity (6).
Download or read book Biological Response Modifiers written by Paul F. Torrence and published by . This book was released on 1985 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Resistance As a Biochemical Target in Cancer Chemotherapy written by Makoto Ogawa and published by Academic Press. This book was released on 1991-11-12 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Resistance as a Biochemical Target in Cancer Chemotherapy covers the proceedings of the 13th Bristol-Myers Squibb Symposium on Cancer Research, entitled ""Drug Resistance as a Biochemical Target in Cancer Chemotherapy"", hosted by the Japanese Foundation for Cancer Research in Tokyo. This book is divided into four parts encompassing 18 chapters that summarize the results of both preclinical and clinical research on circumvention of drug resistance. The first two parts discuss the genetic aspects of multidrug resistance and the proteins involved in drug resistance. These parts also examine the structure, function, and expression of P-glycoproteins, with an emphasis on the role of these proteins as targets for cancer chemotherapy. The third part describes the methods for detection of P-glycoprotein and its antagonists to counter clinical drug resistance. This topic is followed by a discussion on the interactions among steroid hormones, steroid hormone receptors, antiandrogens, biological-response modifiers, and cytotoxic drugs in human breast cancer. The concluding part explores the clinical applications of chemosensitizers in cancer therapy. This part also considers the alternative clinical approaches against drug failure, including non-crosss-resistant therapies, autologous bone marrow transplantation, dose-intensive therapy, and high-dose chemotherapy. Biomedical scientists and researchers and clinicians will find this book invaluable.
Download or read book Annual Report written by National Cancer Institute (U.S.). Division of Cancer Treatment and published by . This book was released on 1981 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
