Download or read book CalDAG 2009 written by Michael Patrick Gibbens and published by . This book was released on 2008 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pathophysiology Pharmacology and Biochemistry of Dyskinesia written by Jonathan Brotchie and published by Academic Press. This book was released on 2011-09-19 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Download or read book Handbook of Brain Microcircuits written by Gordon M. Shepherd and published by Oxford University Press. This book was released on 2018 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to focus on principles, each chapter in this work is brief, organized around 1-3 wiring diagrams of the key circuits, with several pages of text that distil the functional significance of each microcircuit
Download or read book Striatal Signaling Two Decades of Progress written by Emmanuel Valjent and published by Frontiers E-books. This book was released on with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic aims to highlight and cover recent understanding on striatal signaling pathways, which are activated by a variety of therapeutic agents or drugs of abuse in physiological and pathological context. The recent development of different mouse models allowing the identification of specific cell types and neuronal circuits in which a given signaling pathway is activated in various physiological and pathological conditions provides essential information and allowed to untangle the complexity of study signal transduction in the brain in vivo.
Download or read book Handbook of Brain Microcircuits written by Gordon Shepherd and published by Oxford University Press. This book was released on 2010-09-22 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microcircuits are the specific arrangements of cells and their connections that carry out the operations unique to each brain region. This resource summarizes succinctly these circuits in over 40 regions - enabling comparisons of principles across both vertebrates and invertebrates. It provides a new foundation for understanding brain function that will be of interest to all neuroscientists. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Download or read book Molecular and Cellular Biology of Platelet Formation written by Harald Schulze and published by Springer. This book was released on 2017-02-07 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives a comprehensive insight into platelet biogenesis, platelet signal transduction, involvement of platelets in disease, the use of diverse animal models for platelet research and future perspectives in regard to platelet production and gene therapy. Being written by international experts, the book is a concise state-of-the art work in the field of platelet biogenesis, biology and research. It represents an indispensable tool for research scientists in biomedicine, vascular biology, hematopoiesis and hemostasis and specifically for scientists in platelet research, as well as for clinicians in the field of hematology and transfusion medicine.
Download or read book Arrest chemokines written by Klaus Ley and published by Frontiers Media SA. This book was released on 2015-05-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arrest chemokines are a small group of chemokines that promote leukocyte arrest from rolling by triggering rapid integrin activation. Arrest chemokines have been described for neutrophils, monocytes, eosinophils, naïve lymphocytes and effector memory T cells. Most arrest chemokines are immobilized on the endothelial surface by binding to heparin sulfate proteoglycans. Whether soluble chemokines can promote integrin activation and arrest is controversial (Alon-Gerszten). Many aspects of the signaling pathway from the GPCR chemokine receptor to integrin activation are the subject of active investigation. Leukocyte adhesion deficiency III is a human disease in which chemokine-triggered integrin activation is defective because of a mutation in the cytoskeletal protein kindlin-3. About 10 different such mutations have been described. The defects seen in patients with LAD-III elucidate the importance of rapid integrin activation for host defense in humans. We welcome reports that help clarifying this crucial first step in the process of leukocyte transendothelial migration.
Download or read book Minerals Yearbook written by and published by . This book was released on 2013 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Building Construction written by Gang Chen and published by ArchiteG, Inc.. This book was released on 2010 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn the Tips, Become One of Those Who Know Building Construction and Architectural Practice, and Thrive! For architectural practice and building design and construction industry, there are two kinds of people: those who know, and those who don't. The tips of building design and construction and project management have been undercover-until now. Most of the existing books on building construction and architectural practice are too expensive, too complicated, and too long to be practical and helpful. This book simplifies the process to make it easier to understand and uncovers the tips of building design and construction and project management. It sets up a solid foundation and fundamental framework for this field. It covers every aspect of building construction and architectural practice in plain and concise language and introduces it to all people. Through practical case studies, it demonstrates the efficient and proper ways to handle various issues and problems in architectural practice and building design and construction industry. It is for ordinary people and aspiring young architects as well as seasoned professionals in the construction industry. For ordinary people, it uncovers the tips of building construction; for aspiring architects, it works as a construction industry survival guide and a guidebook to shorten the process in mastering architectural practice and climbing up the professional ladder; for seasoned architects, it has many checklists to refresh their memory. It is an indispensable reference book for ordinary people, architectural students, interns, drafters, designers, seasoned architects, engineers, construction administrators, superintendents, construction managers, contractors, and developers. You will learn: 1. How to develop your business and work with your client. 2. The entire process of building design and construction, including programming, entitlement, schematic design, design development, construction documents, bidding, and construction administration. 3. How to coordinate with governing agencies, including a county's health department and a city's planning, building, fire, public works departments, etc. 4. How to coordinate with your consultants, including soils, civil, structural, electrical, mechanical, plumbing engineers, landscape architects, etc. 5. How to create and use your own checklists to do quality control of your construction documents. 6. How to use various logs (i.e., RFI log, submittal log, field visit log, etc.) and lists (contact list, document control list, distribution list, etc.) to organize and simplify your work. 7. How to respond to RFI, issue CCDs, review change orders, submittals, etc. 8. How to make your architectural practice a profitable and successful business. About the author Gang Chen holds a master's degree from the School of Architecture, University of Southern California (USC), Los Angeles, and a bachelor's degree from the School of Architecture, South China University of Technology. He has over 20 years of professional experience. Many of the projects he was in charge of or participated in have been published extensively in Architecture, Architectural Record, The Los Angeles Times, The Orange County Register, etc. He has worked on a variety of unusual projects, including well-known, large-scale healthcare and hospitality projects with over one billion dollars in construction costs, award-winning school designs, highly-acclaimed urban design and streetscape projects, multifamily housing, high-end custom homes, and regional and neighborhood shopping centers. Gang Chen is a LEED AP and a licensed architect in California. He is also the internationally acclaimed author for other fascinating books, including Planting Design Illustrated and LEED Exam Guides Series, which include one guidebook for each of the LEED exams.
Download or read book Ras Superfamily Small G Proteins Biology and Mechanisms 1 written by Alfred Wittinghofer and published by Springer. This book was released on 2014-09-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.
Download or read book Primary Immunodeficiency Diseases written by Hans D. Ochs, and published by . This book was released on 2013-09 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of Primary Immunodeficiency Diseases provides readers with the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings of this rapidly enlarging class of diseases.
Download or read book Platelets Haemostasis and Inflammation written by Andreas Zirlik and published by Springer. This book was released on 2017-12-21 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials. The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.
Download or read book Antiplatelet Agents written by Paolo Gresele and published by Springer Science & Business Media. This book was released on 2012-08-23 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.
Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2016-09-15 with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition. These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. This updated edition has been thoroughly revised to provide the most up-to-date account of this critical brain structure. Edited and authored by internationally acclaimed basal ganglia researchers, the new edition contains ten entirely new chapters that offer expanded coverage of anatomy and physiology, detailed accounts of recent advances in cellular/molecular mechanisms and cellular/physiological mechanisms, and critical, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cellular/molecular and cellular/physiological mechanisms, and behavioral and clinical aspects of function and dysfunction Written by international authors who are preeminent researchers in the field Explores, in full, the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Download or read book The Basal Ganglia written by Jean-Jacques Soghomonian and published by Springer. This book was released on 2016-11-04 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking text takes current knowledge of the basal ganglia far from well-known motor-based models to a more inclusive understanding of deep-brain structure and function. Synthesizing diverse perspectives from across the brain-behavioral sciences, it tours the neuroanatomy and circuitry of the basal ganglia, linking their organization to their controlling functions in core cognitive, behavioral, and motor areas, both normative and disordered. Interactions between the basal ganglia and major structures of the brain are identified in their contributions to a diverse range of processes, from language processing to decision-making, emotion to visual perception, motivation to intent. And the basal ganglia are intimately involved in the mechanisms of dysfunction, as evinced by chapters on dyskinesia, Parkinson’s disease, neuropsychiatric conditions, and addictions. Included in the coverage: Limbic-basal ganglia circuits: parallel and integrative aspects. Dopamine and its actions in the basal ganglia system. Cerebellar-basal ganglia interactions. The basal ganglia contribution to controlled and automatic processing. The basal ganglia and decision making in neuropsychiatric disorders. The circuitry underlying the reinstatement of cocaine seeking: modulation by deep brain stimulation. The basal ganglia and hierarchical control in voluntary behavior. Its breadth and depth of scholarship and data should make The Basal Ganglia a work of great interest to cognitive psychologists and neuroscientists, neuropsychologists, neurologists, neuropsychiatrists, and speech-language pathologists.
Download or read book California Code of Regulations written by and published by . This book was released on 2013 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This document is Part 2 of 12 parts of the official triennial compilation and publication of the adoptions, amendments and repeal of administrative regulations to California Code of Regulations, Title 24, also referred to as the California Building Standards Code. This part is known as the California Building Code"--Preface.
Download or read book Minerals Yearbook Area Reports written by and published by Government Printing Office. This book was released on 2011-10-30 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Minerals Yearbook is an annual publication that reviews the mineral and material industries of the United States and foreign countries. The Yearbook contains statistical data on materials and minerals and includes information on economic and technical trends and development. The Minerals Yearbook includes chapters on approximately 90 commodities and over 175 countries. This volume of the Minerals Yearbook provides an annual review of mineral production and trade and of mineral-related government and industry developments in more than 175 foreign countries. Each report includes sections on government policies and programs, environmental issues, trade and production data, industry structure and ownership, commodity sector developments, infrastructure, and a summary outlook.
