Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by Heinrich Schmidt-Gayk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are deA scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.
Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by and published by . This book was released on 1990 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by Heinrich Schmidt-Gayk and published by Springer. This book was released on 1990-10-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are deA scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.
Download or read book Assay of Calcium regulating Hormones written by D. D. Bikle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure accurately the hormones regulating calcium homeosta sis is the fundamental first step toward understanding the roles these hormones play in health and disease. Techniques for such measurements have only been available for the past 10 years or so and remain in a state of rapid development. Sensitive parathyroid hormone (PTH) radioimmunoassays appeared in the early 1970s, and with them came a whole new appreciation for the prevalence and implications of hyperparathyroidism, primary or secondary, in the popu lation. The calcitonin (CT) radioimmunoassay came later and achieved rapid success in the. diagnosis of a previously poorly understood cancer, medullary carcinoma of the thyroid, frequently associated with the familial multiple endo crine neoplasia type 2 syndromes (a and b). As the sensitivity of the calcitonin radioimmunoassay has improved, our understanding of the role of calcitonin in normal physiological processes has increased. The knowledge that vitamin D must be metabolized to produce its biologic effects is only 15 years old. This has had profound implications in our understanding of a variety of metabolic bone, kidney, and gastrointestinal diseases. Assays to measure the major cir culating form of vitamin D, 25-hydroxyvitamin D, were described 10 years ago. Assays for the other metabolites, in particular, 1,25-dihydroxyvitamin D, were described even more recently. As of today, we know of many vitamin D metabolites and have developed the techniques to measure most of them; how ever, many questions remain concerning their physiological role.
Download or read book Assay of Calcium regulating Hormones written by Daniel Bikle and published by Springer. This book was released on 1983-10-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure accurately the hormones regulating calcium homeosta sis is the fundamental first step toward understanding the roles these hormones play in health and disease. Techniques for such measurements have only been available for the past 10 years or so and remain in a state of rapid development. Sensitive parathyroid hormone (PTH) radioimmunoassays appeared in the early 1970s, and with them came a whole new appreciation for the prevalence and implications of hyperparathyroidism, primary or secondary, in the popu lation. The calcitonin (CT) radioimmunoassay came later and achieved rapid success in the. diagnosis of a previously poorly understood cancer, medullary carcinoma of the thyroid, frequently associated with the familial multiple endo crine neoplasia type 2 syndromes (a and b). As the sensitivity of the calcitonin radioimmunoassay has improved, our understanding of the role of calcitonin in normal physiological processes has increased. The knowledge that vitamin D must be metabolized to produce its biologic effects is only 15 years old. This has had profound implications in our understanding of a variety of metabolic bone, kidney, and gastrointestinal diseases. Assays to measure the major cir culating form of vitamin D, 25-hydroxyvitamin D, were described 10 years ago. Assays for the other metabolites, in particular, 1,25-dihydroxyvitamin D, were described even more recently. As of today, we know of many vitamin D metabolites and have developed the techniques to measure most of them; how ever, many questions remain concerning their physiological role.
Download or read book Hormonal Control of Calcium Metabolism written by David V. Cohn and published by . This book was released on 1981 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1991 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vitamin D written by A. W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Vitamin D".
Download or read book Diagnostics of Endocrine Function in Children and Adolescents written by Michael B. Ranke and published by Karger Medical and Scientific Publishers. This book was released on 2003-01-01 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: The completely revised and expanded third edition offers a comprehensive, up-to-date overview of the diagnostics of endocrine function as well as normal reference values for the differential diagnosis of the major endocrine disorders in the pediatric and adolescent age group. Leading international specialists present in-depth rational diagnostic strategies based on pathogenetic considerations and extensive personal experience. Recent developments in assay and imaging techniques are presented in detail, and their clinical relevance is evaluated. Easy-to-use tables and figures allow quick reference. Flowcharts of possible diagnostic pathways lead to the most frequent diagnoses. With its broad range of diagnostic methods and protocols in compact and readable form, this volume will be an indispensable reference tool not only for endocrinologists but also for pediatricians and professionals in other specialties seeking guidance on how to deal with complex differential diagnostic situations.
Download or read book Hypercalcemia of Malignancy written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.
Download or read book The Role of Dietary Supplements for Physically Active People written by Kristine M. Scannell and published by DIANE Publishing. This book was released on 1996-09 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides 762 citations from journals, technical reports & books related to the use of dietary supplements in humans for physical activity & recreational sports. Contents: metabolic basis of supplementation; macronutrients & amino acids (protein, carbohydrates, water & electrolytes, branched chain amino acids, glutamine); minerals (calcium, iron, magnesium, zinc, chromium & copper) other supplements for the physically active (B vitamins, creatine, carnitine, choline, herbs); antioxidants (vitamins E & C, selenium); & laboratory methodologies.
Download or read book Current Bibliographies in Medicine written by and published by . This book was released on 1988 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vitamin D written by H.F. DeLuca and published by Springer. This book was released on 2011-12-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because diseases of the bone are often less acute and less lifethreatening than dis eases of the circulatory system, gastrointestinal tract, kidney, liver, and the nervous system, they have received a disproportionately smaller amount of attention in the medical world. With the average increasing life span of man as a result of improve ments in modern medicine, espe~ially in the pediatric field, the seriousness of many metabolic bone diseases has indeed become more obvious. In addition, other improvements in medicine, such as hemodialysis for the preservation of renal failure patients, have permitted the development of other consequences of diseased kidneys, one of which is the appearance of renal osteodystrophy. Finally, the appearance of several genetic disorders in the area of metabolic bone disease has been underscored by the solution of other pediatric diseas~s of much more serious consequences. These emerging problems all suggest that much remains to be learned concerning the sys temic control of bone, both as a structural organ and as a reservoir for the important elements of calcium and phosphorus so essential for the support of life in complex multicellular organisms of which man is the most important. As will be demonstrated in the historical portion of this manuscript, the existence of the three most important humoral factors regulating bone metabolism and func tion are now known.
Download or read book Medullary Thyroid Carcinoma written by Friedhelm Raue and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medullary Thyroid Carcinoma is a rare thyroid tumor originating from neural crest cells, the C-cell that implies several special features, secretion of different neuroendocrine markers, association with other endocrine tumors and familial appearance. The familial variant of medullary thyroid carcinoma allows an early detection by biochemical and genetic testing. At that stage acceptable surgical treatment will cure the patient. The sporadic form of medullary thyroid carcinoma will be diagnosed in a progressive stage, but adequate surgical procedure can cure these patients too. Long term survival depends on stage, age, sex, and variant of the disease and seems to be as good as in other differentiated thyroid cancers.
Download or read book Neuropeptides written by Fleur L. Strand and published by MIT Press. This book was released on 1999 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.
Download or read book Vitamin D Biochemical Chemical and Clinical Aspects Related to Calcium Metabolism written by A. W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-26 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Vitamin D - Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism".
