Download or read book Assay of Calcium regulating Hormones written by D. D. Bikle and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure accurately the hormones regulating calcium homeosta sis is the fundamental first step toward understanding the roles these hormones play in health and disease. Techniques for such measurements have only been available for the past 10 years or so and remain in a state of rapid development. Sensitive parathyroid hormone (PTH) radioimmunoassays appeared in the early 1970s, and with them came a whole new appreciation for the prevalence and implications of hyperparathyroidism, primary or secondary, in the popu lation. The calcitonin (CT) radioimmunoassay came later and achieved rapid success in the. diagnosis of a previously poorly understood cancer, medullary carcinoma of the thyroid, frequently associated with the familial multiple endo crine neoplasia type 2 syndromes (a and b). As the sensitivity of the calcitonin radioimmunoassay has improved, our understanding of the role of calcitonin in normal physiological processes has increased. The knowledge that vitamin D must be metabolized to produce its biologic effects is only 15 years old. This has had profound implications in our understanding of a variety of metabolic bone, kidney, and gastrointestinal diseases. Assays to measure the major cir culating form of vitamin D, 25-hydroxyvitamin D, were described 10 years ago. Assays for the other metabolites, in particular, 1,25-dihydroxyvitamin D, were described even more recently. As of today, we know of many vitamin D metabolites and have developed the techniques to measure most of them; how ever, many questions remain concerning their physiological role.
Download or read book Store Operated Calcium Channels written by and published by Academic Press. This book was released on 2013-07-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels Contributors are authoritative researchers who have produced important advances in the field The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
Download or read book Calcium regulating Hormones written by Hirotoshi Morii and published by . This book was released on 1991 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by Heinrich Schmidt-Gayk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are deA scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.
Download or read book Basic Physiology written by P.D. Sturkie and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Physiology is an introduction to vertebrate physiology, stressing human physiology at the organ level, and includ ing requisite anatomy integrated with function. One chapter deals solely with topographic anatomy in atlas form and microscopic anatomy of the principal tissues of the body. Additional chapters cover cellular and general physiology; nervous system, muscle; blood and tissue fluids, heart and circulation; respiration, digestion and absorption; intermedi ary metabolism; energy metabolism; temperature regulation; nutrition; kidney; endocrinology, including hypophysis, re production; thyroids, parathyroids, adrenals and pancreas. All concepts are emphasized and well illustrated, and con troversial material is omitted. It is written at a level suited to undergraduate students who have had introductory courses in biology, chemistry, and mathematics, and to more ad vanced students who wish to review the basic concepts of physiology. This volume should be especially useful as a text for de partments of biology, zoology, nursing, health, and agricul tural sciences that offer courses in vertebrate and human physiology. Basic Physiology is written by seven subject matter special ists who have considerable experience in teaching their specialty to undergraduates studying physiology and biology.
Download or read book Erythropoietin in the 90s written by R. M. Schaefer and published by . This book was released on 1990 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormonal Control of Calcium Metabolism written by David V. Cohn and published by . This book was released on 1981 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Regulating Hormones and Cardiovascular Function written by M.F. Crass, III and published by CRC Press. This book was released on 1994-12-27 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to exclusively address the actions of calcium-regulating hormones and peptides in the cardiovascular system. With 111 illustrations and 13 tables, this comprehensive volume includes: An extensive and critical review of present knowledge of the structure, synthesis, secretion, metabolism, receptors, signal transduction, and actions on classical target cells of each of the calcium-regulating hormones and peptides Discussions on parathyroid hormone and calcitonin, parathyroid hormone-related protein, parathyroid hypertensive factor, 1,25 dihydroxyvitamin D3, calcitonin gene-related peptide, and certain steroid hormones in terms of vascular biology and cardiac function The integrated physiology of calcium-regulating hormones in terms of blood pressure regulation in normotensive and hypertensive settings State-of-the-art electrophysiological techniques used by leading cardiovascular biologists to assess calciotropic hormone effects on calcium channel currents in both vascular smooth muscle and cardiac myocytes Studies on the regulation of hormone and receptor gene expression in the context of possible regulation of local and systemic blood flow and cardiac function by calcium-regulating hormones and peptides
Download or read book Phosphate Metabolism written by Shaul Massry and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.
Download or read book Bone Health and Osteoporosis written by United States Public Health Service and published by . This book was released on 2004-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Download or read book Current Research on Calcium regulating Hormones written by Cary Wayne Cooper and published by . This book was released on 1987 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hormonal Control of Calcium Metabolism written by Colo.) International Conference on Calcium Regulating Hormones (7th : 1980 : Estes Park and published by . This book was released on 1981 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by Heinrich Schmidt-Gayk and published by Springer. This book was released on 1990-10-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are deA scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.
Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.
Download or read book Hormones written by Anthony W. Norman and published by Academic Press. This book was released on 2014-06-28 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Download or read book Calcium regulating Hormones written by and published by . This book was released on 1975 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium regulating Hormones Role in disease and aging written by Hirotoshi Morii and published by . This book was released on 1991 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
