Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by . This book was released on 1980 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium Entry Channels in Non Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Download or read book Integration of Mitochondrial Function written by J.J. Lemasters and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: In aerobic tissues such as heart, brain, kidney, liver and brown fat, mitochon dria account for more than 20% of cell protein and play an essential role in res piration, ATP formation, ketogenesis, gluconeogenesis, amino acid metabolism, ureagenesis, thermogenesis and a variety of other metabolic activities. The mecha nisms by which these activities are integrated and regulated within the overall context of cellular physiology is of much current research interest. In order to bring together scientists examining the various diverse aspects of this overall pro blem, an International Conference on INTEGRATION OF MITOCHONDRIAL FUNC TION was held June 4-7, 1987 at the Hanes Art Center on the campus of the Uni versity of North Carolina at Chapel Hill. The chapters of this volume derive from presentations made at this conference. The focus of INTEGRATION OF MITOCHONDRIAL FUNCTION is on signifi cant new experimental and theoretical advances concerning integration of mito chondrial function at the organelle, cell, tissue and whole organism levels of organization.
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-10-22 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium and Cell Function, Volume V emphasizes the roles of calcium in cellular functions. This book consists of eight chapters. Chapter 1 presents evidence for the role of calmodulin in cell proliferation. The role of calcium in the control of cyclic AMP metabolism in glial and pituitary tumor cells is analyzed in Chapter 2. Chapter 3 explains the evidence that calmodulin regulates neurotransmitter synthesis, while Chapter 4 deliberates the role of calcium in adipocytes. Chapter 5 is devoted to the modulatory function of lipomodulin in cellular phospholipid metabolism. The pharmacological properties of naphthalenesulfonamides as calmodulin antagonists, phophorylase kinase, and phospholipidsensitive calcium-dependent protein kinase are reviewed in the last chapters. This volume is valuable to biologists and medical practitioners interested in calcium and cell function.
Download or read book Store Operated Calcium Channels written by and published by Academic Press. This book was released on 2013-07-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject
Download or read book Calcium and Cell Function written by Wai Y. Cheung and published by . This book was released on 1982 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium and Calmodulin Function in the Cell Nucleus written by Oriol Bachs and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the role of calcium and calmodulin in the cell nucleus. Calcium, which is an important second messenger of signal transduction pathways, can also operate in the cell nucleus. Different calcium binding proteins, which are the targets of cellular calcium, have been identified in the nucleus of many different cell types. Prominent among these calcium binding proteins is calmodulin, which appears to be involved in the regulation of major nuclear functions such as gene expression and DNA replication.
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-10-22 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium and Cell Function, Volume 7 covers the signal transduction across the cell membrane. The book discusses phosphoinositides and calcium signaling; calmodulin-stimulated adenylate cyclases; and calcium/calmodulin-dependent protein kinases. The text also describes the regulation of gene expression by calcium; the dynamics of intracellular calcium concentration during mitosis; and the methods for the measurement of intracellular ionized calcium in mammalian cells. Pharmacologists, physiologists, and people involved in the study of calcium and cell function will find the book invaluable.
Download or read book Cell Calcium Metabolism written by Gary Fiskum and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: A widespread appreciation for the role that calcium plays in cell physiology and patho physiology has now been achieved due to the pioneering studies of many of the scientists who attended the VIIth International Spring Symposium on Health Sciences at George Washington University in Washington, D. C. The participants in this unique meeting rep resented diverse fields of basic and clinical research, such as molecular physiology, oncology, molecular genetics, cardiology, bioenergetics, pathology, and endocrinology. The content of the proceedings of the symposium represents work in these and other areas of biomedical research. Organization of the book is aimed at striking a balance between the biochemistry 2 and physiology of normal cell Ca + metabolism and the pathological consequences of al 2 terations in cell Ca + homeostasis. The first section of the book is devoted to the transport mechanisms responsible for 2 2 regulating intracellular Ca + and the pharmacological modalities for controlling cell Ca + . Particular attention is given to the molecular basis for plasma membrane transport activities, 2 2 including the ATP-driven Ca + pump, the Na + -Ca + exchange system, and voltage sensitive 2 Ca + channels. The second section covers the exciting relationships between phosphoinositide metab 2 olism, signal transduction, and cell Ca + metabolism. This section begins with an eloquent overview by Professor Michael Berridge, who was the keynote speaker at the symposium and the recipient of the scientific merit award.
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-09-03 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium And Cell Function, Volume II covers the status of the multifunctional role of calcium in cell function. The book discusses the chemistry and metabolism of calcium, the various calcium-binding proteins in addition to calmodulin; and the functions of calcium, some mediated by calmodulin and some by other proteins. Physiologists, oncologists, and biochemists will find the book invaluable.
Download or read book Calcium as a Cellular Regulator written by Ernesto Carafoli and published by Oxford University Press, USA. This book was released on 1999 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encompassing all aspects of calcium signalling, from methods of measuring calcium in cells to the molecular mechanisms for decoding its information, this comprehensive book balances historical aspects and state of the art developments.
Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-10-22 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium and Cell Function, Volume I: Calmodulin covers calmodulin-regulated functions. The book discusses the preparation, properties, structure, function, evolution, and structure-function relationships of calmodulin; and calmodulin-dependent adenylate cyclase. The text also describes the transport of calmodulin and plasma membrane calcium; the role of calmodulin and troponin in the regulation of phosphorylase kinase from mammalian skeletal muscle; and calcium-dependent protein phosphorylation in mammalian brain and other tissues. The role of calmodulin in dopaminergic transmission; the immunocytochemical localization of calmodulin in rat tissues; and the immunocytochemical studies of the localization of calmodulin and caM-BP80 in the brain are also considered. The book further tackles the mechanisms and pharmacological implications of altering calmodulin activity. Molecular cardiologists, biochemists, and pharmacologists will find the book invaluable.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by Academic Press. This book was released on 2013-09-03 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium and Cell Function, Volume III covers the many aspects of research on calcium, dealing with its biochemistry, biology, and pharmacology in animals as well as in plants. The book discusses a novel cellular signaling system based on the integration of phospholipid and calcium metabolism; the transport of calcium by sarcoplasmic reticulum; and the energetics and chemistry for interactions between calmodulin and calmodulin-binding proteins. The text also describes the specificity of trifluoperazine and related phenothiazines for calcium-binding proteins; the structure, function, and regulation of phosphorylase kinase; and the regulation of glycogen synthase by multiple protein kinases. The role of calmodulin in synaptic function and neurosecretion; the stimulation of the synthesis of neurotransmitters by calmodulin-dependent phosphorylation; as well as the role of calcium in axoplasmic transport in nerve are also considered. The book further tackles calcium control of the intestinal microvillus cytoskeleton; the possible role of calmodulin in the regulation of insulin release and protein phosphorylation by calcium and cyclic AMP; and the role of calcium in mediating cellular functions important for growth and development in higher plants. The text also looks into the localization of calmodulin in tissue culture cells; and the characterization and regulation of calcium-dependent neutral protease. Zoologists, cell biologists, biochemists, and pharmacologists will find the book invaluable.
Download or read book Calcium Signaling written by Md. Shahidul Islam and published by Springer Nature. This book was released on 2019-10-23 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
