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Download or read book Genomic Applications in Pathology written by George Jabboure Netto and published by Springer. This book was released on 2018-12-10 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases. As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists, hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians. With periodic updates and a sufficiently rapid time from submission to publication, this textbook will be the resource of choice for many professionals and teaching programs. Its focus on genomics parallels the evolution of these technologies as primary methods in the clinical lab. The rapid evolution of genomics and its applications in medicine necessitates the (frequent) updating of this publication. This text will provide a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies. Implementation roadmaps for various clinical assays such as single gene, gene panels, whole exome and whole genome assays will be discussed together with issues related to reporting and the pathologist’s role in interpretation and clinical integration of genomic tests results. Genomic applications for site-specific solid tumors and hematologic neoplasms will be detailed. Genomic applications in pharmacogenomics, inherited genetic diseases and infectious diseases will also be discussed. The latest iteration of practice recommendations or guidelines in genomic testing put forth by stakeholder professional organizations such as the College of American Pathology and the Association for Molecular Pathology, will be discussed as well as regulatory issues and laboratory accreditation related to genomic testing. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

Download or read book Access to Justice written by Deborah L. Rhode and published by Oxford University Press. This book was released on 2004-09-23 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Equal Justice Under Law" is one of America's most proudly proclaimed and widely violated legal principles. But it comes nowhere close to describing the legal system in practice. Millions of Americans lack any access to justice, let alone equal access. Worse, the increasing centrality of law in American life and its growing complexity has made access to legal assistance critical for all citizens. Yet according to most estimates about four-fifths of the legal needs of the poor, and two- to three-fifths of the needs of middle-income individuals remain unmet. This book reveals the inequities of legal assistance in America, from the lack of access to educational services and health benefits to gross injustices in the criminal defense system. It proposes a specific agenda for change, offering tangible reforms for coordinating comprehensive systems for the delivery of legal services, maximizing individual's opportunities to represent themselves, and making effective legal services more affordable for all Americans who need them.

Download or read book John T Racanelli written by Tom Racanelli and published by Createspace Independent Publishing Platform. This book was released on 2015-10-21 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: John T. Racanelli was born in Lansdowne, Pennsylvania in 1925. The son of Italian immigrants, John Sr. and Mary Racanelli, he was raised in New York City and later in White Plains, New York. After high school, he enlisted in the United States Army Air Corps (now called the Air Force) and served as Lieutenant as an Aerial Navigator. He served in World War II and the Korean War for over 3 years in active duty. He was the first person in his family to attend college where he attended the University of California at Berkeley and later Hastings Law School. After college and law school, he started a private practice in San Francisco in 1953. In 1955, he moved to Sunnyvale and started practicing there. In his private practice, he specialized as a trial lawyer in all types of civil and criminal proceedings. His partners included the Honorable James Duvaras (1955 - 1963) and Anthony J. Treppel, Esq. (1963 - 1964). He was appointed to Superior Court Judge in Santa Clara County by Governor (Pat) Brown, Sr., and sworn in on October 16, 1964. He served in that capacity until he was appointed by Governor (Jerry) Brown, Jr. on May 6, 1977 to Presiding Justice, Court of Appeal, First Appellate District, Division One (succeeding Presiding Justice John B. Molinari). He was sworn in on June 3, 1977 and confirmed by electorate on November 7, 1978, and later reconfirmed by electorate on November 2, 1982. He retired from the bench on deferred retirement on January 31, 1991. Since his retirement, he has enjoyed his life with his wife of over 30 years, Betty Medsger. They live in New York City.