Download or read book Arthrogryposis written by Lynn T. Staheli and published by Cambridge University Press. This book was released on 1998-04-28 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term arthrogryposis describes a range of congenital contractures that lead to childhood deformities. It encompasses a number of syndromes and sporadic deformities that are rare individually but collectively are not uncommon. Yet, the existing medical literature on arthrogryposis is sparse and often confusing. The aim of this book is to provide individuals affected with arthrogryposis, their families, and health care professionals with a helpful guide to better understand the condition and its therapy. With this goal in mind, the editors have taken great care to ensure that the presentation of complex clinical information is at once scientifically accurate, patient oriented, and accessible to readers without a medical background. The book is authored primarily by members of the medical staff of the Arthrogryposis Clinic at Children's Hospital and Medical Center in Seattle, Washington, one of the leading teams in the management of the condition, and will be an invaluable resource for both health care professionals and families of affected individuals.

Download or read book Prokaryotic Antimicrobial Peptides written by Djamel Drider and published by Springer Science & Business Media. This book was released on 2011-03-08 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products. Antimicrobial peptides stand as potentially great alternatives to current antibiotics, and most research in this newly-created area has been published in journals and other periodicals. It is the editors’ opinion that it is timely to sum up the most important achievements in the field and provide the scientific community in a reference book. The goals of this project include illustrating the achievements made so far, debating the state of the art, and drawing new perspectives.

Download or read book The Glutamate Receptors written by Robert W. Gereau and published by Springer Science & Business Media. This book was released on 2008-02-23 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This insightful and comprehensive book covers nearly every aspect of glutamate receptor structure and function for the working researcher and student. It condenses two previous landmark volumes into one easily accessible volume, and covers the extraordinary research and significant developments in the decade since the previous books were published. This includes the central role glutamate receptors play in neurotransmission.

Download or read book Recent Advances In Retinal Degeneration written by Robert E. Anderson and published by Springer Science & Business Media. This book was released on 2007-12-03 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The product of perhaps the most important research meeting in the field, this essential text outlines all the latest research in retinal degeneration. Culled from the proceedings of the International Symposium on the subject, the topics in this volume explore the etiology, cellular mechanisms, epidemiology, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration. A must-read for researchers in the field.

Download or read book Coastal Sediments 2019 Proceedings Of The 9th International Conference written by Ping Wang and published by World Scientific. This book was released on 2019-05-17 with total page 3050 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Proceedings contains over 260 papers on cutting-edge research presented at the 9th International Conference on Coastal Sediments 2019 (CS19), held in Tampa/St. Petersburg, Florida, USA from May 27-31, 2019. This technical specialty conference is devoted to promoting an interdisciplinary exchange of state-of-the-art knowledge among researchers in the fields of coastal engineering, geology, oceanography, and related disciplines.With the theme of 'Advancing Science & Engineering for Resilient Coastal Systems', this Proceedings covers a wide range of research topics on coastal sediment processes from nearshore sediment transport and modelling to beach processes, shore protection, and coastal management.

Download or read book Neurofibromatosis Type 1 written by Meena Upadhyaya and published by Springer Science & Business Media. This book was released on 2013-01-29 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome. Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

Download or read book Rutter s Child and Adolescent Psychiatry written by Anita Thapar and published by John Wiley & Sons. This book was released on 2015-06-15 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rutter's Child and Adolescent Psychiatry is the leading textbook in its field. Both interdisciplinary and international, it provides a coherent appraisal of the current state of the field to help researchers, trainees and practicing clinicians in their daily work. Integrating science and clinical practice, it is a comprehensive reference for all aspects of child and adolescent psychiatry. New to this full color edition are expanded coverage on classification, including the newly revised Diagnostic and Statistical Manual of Mental Disorders (DSM-5), and new chapters on systems neuroscience, relationship-based treatments, resilience, global psychiatry, and infant mental health. From an international team of expert editors and contributors, this sixth edition is essential reading for all professionals working and learning in the fields of child and adolescent mental health and developmental psychopathology as well as for clinicians working in primary care and pediatric settings. Michael Rutter has contributed a number of new chapters and a Foreword for this edition: "I greatly welcome this new edition as providing both a continuity with the past and a substantial new look." —Professor Sir Michael Rutter, extract from Foreword. Reviews of previous editions: "This book is by far the best textbook of Child & Adolescent Psychiatry written to date." —Dr Judith Rapoport, NIH "The editors and the authors are to be congratulated for providing us with such a high standard for a textbook on modern child psychiatry. I strongly recommend this book to every child psychiatrist who wants a reliable, up-to-date, comprehensive, informative and very useful textbook. To my mind this is the best book of its kind available today." —Journal of Child Psychology and Psychiatry

Download or read book Developmental Psychopathology Developmental Neuroscience written by Dante Cicchetti and published by John Wiley & Sons. This book was released on 2016-02-29 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complete reference of biological bases for psychopathology at any age Developmental Psychopathology is a four-volume compendium of the most complete and current research on every aspect of the field. Volume Two: Developmental Neuroscience focuses on the biological basis of psychopathology at each life stage, from nutritional deficiencies to genetics to functional brain development to evolutionary perspectives and more. Now in its third edition, this comprehensive reference has been fully updated to better reflect the current state of the field, and detail the newest findings made possible by advances in technology and neuroscience. Contributions from expert researchers and clinicians provide insight into brain development, molecular genetics methods, neurogenics approaches to pathway mapping, structural neuroimaging, and much more, including targeted discussions of specific disorders. Advances in developmental psychopathology have burgeoned since the 2006 publication of the second edition, and keeping up on the latest findings in multiple avenues of investigation can be burdensome to the busy professional. This series solves the problem by collecting the information into one place, with a logical organization designed for easy reference. Consider evolutionary perspectives in developmental psychopathology Explore typical and atypical brain development across the life span Examine the latest findings on stress, schizophrenia, anxiety, and more Learn how genetics are related to psychopathology at different life stages The complexity of a field as diverse as developmental psychopathology deepens with each emerging theory, especially with consideration of the rapid pace of neuroscience advancement and genetic discovery. Developmental Psychopathology Volume Two: Developmental Neuroscience provides an invaluable resource by compiling the latest information into a cohesive, broad-reaching reference.

Download or read book Calcium Signalling and Disease written by Ernesto Carafoli and published by Springer Science & Business Media. This book was released on 2007-09-29 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.

Download or read book Human Fetal Tissue Transplantation written by Niranjan Bhattacharya and published by Springer Science & Business Media. This book was released on 2013-02-26 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many diseases earlier considered to be incurable are now being treated with modern innovations involving fetal tissue transplants and stem cells derived from fetal tissues. Fetal tissues are the richest source of fetal stem cells as well as other varying states of differentiated cells and support or stromal cells. The activity of such stem cells is at their peak provided they are given the correct niche. Stem cells, as we know, are immortal cells with the capacity to regenerate into any kind of differentiated cell as per niche-guidance. As such, fetal tissues have the potential capacity to mend, regenerate and repair damaged cells or tissues in adults, when directly transplanted to the site of injury, or even when transplanted in some other site, because it may have a homing capacity to migrate to the site of the specific injured organ. This is a new area of translational research and needs to be highlighted because of its immense potential. This book will bring together the new work of prominent medical scientists and clinicians who are conducting pioneering research in human fetal tissue transplantation. This will include direct transplant of healthy fetal tissue into mature patients as well as in hosts with genetic diseases. Transplant techniques, donor-host interaction, cell and tissue storage, ethical and legal issues, are some of the many matters which the book will deal with.

Download or read book Dragon Bone Hill written by Noel T. Boaz and published by Oxford University Press. This book was released on 2004-02-16 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Peking Man," a cave man once thought a great hunter who had first tamed fire, actually was a composite of the gnawed remains of some fifty women, children, and men unfortunate enough to have been the prey of the giant cave hyena. Researching the famous fossil site of Dragon Bone Hill in China, scientists Noel T. Boaz and Russell L. Ciochon retell the story of the cave's unique species of early human, Homo erectus. Boaz and Ciochon take readers on a gripping scientific odyssey. New evidence shows that Homo erectus was an opportunist who rode a tide of environmental change out Africa and into Eurasia, puddle-jumping from one gene pool to the next. Armed with a shaky hold on fire and some sharp rocks, Homo erectus incredibly survived for over 1.5 million years, much longer than our own species Homo sapiens has been on Earth. Tell-tale marks on fossil bones show that the lives of these early humans were brutal, ruled by hunger and who could strike the hardest blow, yet there are fleeting glimpses of human compassion as well. The small brain of Homo erectus and its strangely unchanging culture indicate that the species could not talk. Part of that primitive culture included ritualized aggression, to which the extremely thick skulls of Homo erectus bear mute witness. Both a vivid recreation of the unimagined way of life of a prehistoric species, so similar yet so unlike us, and a fascinating exposition of how modern multidisciplinary research can test hypotheses in human evolution, Dragon Bone Hill is science writing at its best.

Download or read book The Trauma Manual written by Andrew B. Peitzman and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated Second Edition of this popular and widely used pocket reference guides the trauma team through every aspect of patient care after injury--from prehospital care, to resuscitation, treatment of specific organ injuries, priorities in intensive care, and management of special situations. Designed for rapid, on-the-spot information retrieval, The Trauma Manual, Second Edition will be a staple reference in emergency departments. Flow charts, algorithms, sequential lists, and tables throughout facilitate quick clinical decision-making. More than 100 illustrations demonstrate specific injuries and procedures. Appendices include injury scales, tetanus prophylaxis recommendations, commonly used formulae and values, and frequently used forms. This edition includes a new chapter on commonly missed injuries and common pitfalls.

Download or read book Design for Policy written by Christian Bason and published by Routledge. This book was released on 2016-04-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design for Policy is the first publication to chart the emergence of collaborative design approaches to innovation in public policy. Drawing on contributions from a range of the world’s leading academics, design practitioners and public managers, it provides a rich, detailed analysis of design as a tool for addressing public problems and capturing opportunities for achieving better and more efficient societal outcomes. In his introduction, Christian Bason suggests that design may offer a fundamental reinvention of the art and craft of policy making for the twenty-first century. From challenging current problem spaces to driving the creative quest for new solutions and shaping the physical and virtual artefacts of policy implementation, design holds a significant yet largely unexplored potential. The book is structured in three main sections, covering the global context of the rise of design for policy, in-depth case studies of the application of design to policy making, and a guide to concrete design tools for policy intent, insight, ideation and implementation. The summary chapter lays out a future agenda for design in government, suggesting how to position design more firmly on the public policy stage. Design for Policy is intended as a resource for leaders and scholars in government departments, public service organizations and institutions, schools of design and public management, think tanks and consultancies that wish to understand and use design as a tool for public sector reform and innovation.

Download or read book Bacteriocins Microcins and Lantibiotics written by Richard James and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented here are recent findings on bacteriocins: plasmid-encoded toxins produced by bacteria, which differ from traditional antibiotics in killing only bacteria that are closely related to the producing strain. Included are introductory chapters on bacteriocins, microcins (low molecular weight bacteriocins), and lantibiotics (peptide antibiotics containing lanthionine), further, contributions on pore forming bacteriocins, the mechanisms of immunity to bacteriocins, uptake and secretion, as well as evolution of bacteriocins. It is of particular interest that the lantibiotic nisin is approved for use as food preservative and another lantibiotic, epidermin, has potential as a therapeutic drug against acne.

Download or read book Changing Things written by Johan Redström and published by Bloomsbury Visual Arts. This book was released on 2020-01-09 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the things we now live with do not take a purely physical form. Objects such as smart phones, laptops and wearable fitness trackers are different from our things of the past. These new digital forms are networked, dynamic and contextually configured. They can be changeable and unpredictable, even inscrutable when it comes to understanding what they actually do and whom they really serve. In Changing Things, Johan Redstrom and Heather Wiltse address critical questions that have assumed a fresh urgency in the context of these rapidly-developing forms. Drawing on critical traditions from a range of disciplines that have been used to understand the nature of things, they develop a new vocabulary and a theoretical approach that allows us to account for and address the multi-faceted, dynamic, constantly evolving forms and functions of contemporary things. In doing so, the book prototypes a new design discourse around everyday things, and describes them as 'fluid assemblages'. Redstrom and Wiltse explore how a new theoretical framework could enable a richer understanding of things as fluid and networked, with a case study of the evolution of music players culminating in an in-depth discussion of Spotify. Other contemporary 'things' touched on in their analysis include smart phones and watches, as well as digital platforms and applications such as Google, Facebook and Twitter.

Download or read book The Proceedings of the Coastal Sediments 2011 written by Ping Wang and published by World Scientific. This book was released on 2011-01-01 with total page 921 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings contains nearly 200 papers on cutting-edge research presented at the seventh international Symposium on Coastal Engineering and Science of Coastal Sediment Processes, held May 26, 2011, in Miami, Florida, USA. This technical specialty conference was devoted to promoting an interdisciplinary exchange of state-of-the-art knowledge among researchers in the fields of coastal engineering, geology, oceanography, and related disciplines, with a theme of bringing together theory and practice. Focusing on the physical aspects of sediment processes in various coastal environments, this three-volume conference proceedings provides findings from the latest research and newest engineering applications. Session topics cover a wide range including barrier-island morphodynamics and evolution, beach nourishment and shore protection, coastal dunes, cohesive sediment transport, field and laboratory measurements of sediment transport processes and numerical modeling, gravel transport, large-scale and long-term coastal changes, LiDAR and remote sensing, longshore and cross-shore sediment transport, marsh and wetlands, regional sediment management, river deltas, sea-level changes, shelf and sand bodies, shoreline changes, tidal inlets and navigation channels. A special session on recent research findings at the Northern Gulf of Mexico is also included.

Download or read book Epilepsy written by Jerome Engel and published by Lippincott Williams & Wilkins. This book was released on 2007-09-28 with total page 1272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.