Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Download or read book Brain Protection in Cardiac Surgery written by Robert S. Bonser and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Monographs in Cardiac Surgery Series – Introducing ‘basic science into the cardiac operating room’. Fast systematic review of small areas of cardiac surgery including up-to-date information. This will allow more rapid publication than the alternative cardiac surgery ‘tomes’. This entry into the series will provide readers with a complete review of the current understanding in brain injury and the methods used to avoid or limit its effects on patient morbidity and mortality.
Download or read book Brain Protection written by Klaus Wiedemann and published by Springer. This book was released on 1983 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has doubtlessly been made in the field of cere bral protection compared to earlier centuries, as recently reviewed by Elisabeth Frost (6). She cites the recommendations for treat ment of brain trauma by Areteus, a Greek physician of the second century A. D. He expressed quite modem views with regard to the need for prompt action considering complications that follow even minor symptoms. He advised burr holes for evacuation of hema toma in seizures, the use of diuretics and, most interestingly, also hypothermia. German surgeons of the 17th century had little more to offer than prescriptions of which the most effective constituent was alcohol (10). Thus, Sir Astley Cooper was probably the next surgeon to make noteworthy contributions when advising the use of leeches to the temporal artery and other means of bleeding in stead of surgical intervention in cases of raised intracranial pressure (loc. cit. 6). Although our knowledge has greatly expanded during the last two decades, extensive discussions have led to only few conclusions. Promising results from animal studies were translated to clinical sit uations only to yield controversial and sometimes confusing results. Since the observations of Brierly (5) on ischemic cell damage, im proved information on structural aspects, probably even related to concomitant biochemical studies, should allow the validity of thera peutic concepts to be verified. Investigations on cerebral ischemia have led to the differentiation of synaptic transmission failure and membrane failure.
Download or read book Brain Protection Strategies and Nanomedicine written by and published by Elsevier. This book was released on 2021-10-22 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Protection Strategies and Nanomedicine, Volume 266 in the Progress in Brain Research serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Histamine H3 and H4 receptors modulate Parkinson’s disease induced brain pathology: Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy, Ultra Early Molecular Biologic Diagnosis Of Malignant And Neurodegenerative Diseases By The Immunospecific Profiles Of The Proteins Markers Of The Surface Of The Mobilized Autologous Hematopoietic Stem Cells, Neuroprotective effects of Insulin like growth factor-1 on Engineered metal Nanoparticles Ag, Cu and Al induced blood-brain barrier breakdown, and more. Other chapters cover how Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude: Neuroprotective effects of nanodelivery of a potent antioxidant compound H-290/51, Effectiveness of bortezomib and temozolomide for eradication of recurrent human glioblastoma cells, resistant to radiation, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Progress in Brain Research serials Includes the latest information on brain protection strategies and nanomedicine
Download or read book Sports Related Concussions in Youth written by National Research Council and published by National Academies Press. This book was released on 2014-02-04 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.
Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.
Download or read book Essentials of Neuroanesthesia written by Hemanshu Prabhakar and published by Academic Press. This book was released on 2017-03-24 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Neuroanesthesia offers useful insights on the anesthetic management of neurosurgical and neurologic patients. This book covers all topics related to neuroanesthesia, providing essential knowledge on the brain and spinal cord. Sections include chapters on anatomy, physiology, and pharmacology, along with specific chapters related to various neurosurgical and neurological problems and their anesthetic management. This book provides an understanding of related issues, such as palliative care, evidence based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues, and is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, neuroanesthesia, and neurology. Offers useful insights on the anesthetic management of neurosurgical and neurologic patients Discusses related issues, such as palliative care, evidence based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues Useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, neuroanesthesia, and neurology
Download or read book Power Foods for the Brain written by Neal D Barnard, MD and published by Balance. This book was released on 2013-02-19 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strengthen your memory with New York Times bestselling author Dr. Neal Barnard’s simple 3-step plan to protecting your brain with your diet. Could your breakfast or lunch be harming your memory? Are you missing out on the foods that could prevent Alzheimer's disease? Everyone knows good nutrition supports your overall health, but few realize that certain foods-power foods-can protect your brain and optimize its function, and even dramatically reduce your risk of Alzheimer's Disease. Now, New York Times bestselling author, clinical researcher and health advocate Dr. Neal Barnard has gathered the most up-to-date research and created a groundbreaking program that can strengthen your memory and protect your brain's health. In this effective 3-step plan Dr. Barnard reveals which foods to increase in your diet and which to avoid, and shows you specific exercises and supplements that can make a difference. It will not only help boost brain health, but it can also reduce your risk of Alzheimer's disease, stroke, and other less serious malfunctions such as low energy, poor sleep patterns, irritability, and lack of focus. You'll discover: The best foods to increase cognitive function Dairy products and meats-the dangers they may pose to your memory The surprising roles alcohol and caffeine play in Alzheimer's risk The latest research on toxic metals, like aluminum found in cookware, soda cans, and common antacids. Plus a detailed menu plan, recipes and time-saving kitchen tips
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Download or read book Rewired written by Carl D. Marci MD and published by Harvard University Press. This book was released on 2022-05-17 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Living in an age of digital distraction has wreaked havoc on our brains—but there’s much we can do to restore our tech–life balance. We live in a world that is always on, where everyone is always connected. But we feel increasingly disconnected. Why? The answer lies in our brains. Carl D. Marci, MD, a leading expert on social and consumer neuroscience, reviews the mounting evidence that overuse of smart phones and social media is rewiring our brains, resulting in a losing deal: we are neglecting the relationships that sustain us and keep us healthy in favor of weaker and more ephemeral ties. The ability to connect and form strong social bonds is fundamental to human experience and emerged through unique structures in our brains. But ever-more-powerful technologies and ubiquitous access to media have hijacked our need to connect intimately and emotionally with others. The quick highs of clicking “like” and swiping right overstimulate the same neurological reward centers associated with social relationships. The habits that accompany our digital lifestyles are putting tremendous pressure on critical components of the brain associated with attention, emotion, and memory, changing how we process information and altering how we communicate and relate, even at a physiological level. As a psychiatrist working at the forefront of research on the impact of digital technology, Marci has seen this transformation up close and developed a range of responses. Rewired provides scientifically supported solutions for everyone who wants to restore their tech–life balance—from parents concerned about their children’s exposure to the internet to stressed workers dealing with the deluge of emails and managing the expectation of 24/7 availability.
Download or read book The Age Proof Brain written by Marc Milstein, PhD and published by BenBella Books. This book was released on 2022-10-25 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: “An absolutely fabulous, invaluable read!” —Dr. James B. Maas, Weiss Presidential Fellow, former professor and chair of psychology, Cornell University “A wonderful, life-changing book.” —Brian Tracy, international bestselling author of Eat That Frog! Serious mental decline is not an inevitable part of aging. You can boost your short and long-term brain health and significantly lower the risk of dementia—if the right steps are taken now. Fifty million people have dementia worldwide, but it doesn’t have to be that way. We—not our genes—can control our cognitive destiny. Serious mental decline is not an inevitable part of aging. You can boost your short- and long-term brain health and significantly lower the risk of dementia—if the right steps are taken now. In The Age-Proof Brain, scientist and popular speaker Dr. Marc Milstein reveals the secrets to improving brain function, which lie in the brain’s surprising connection with the rest of the body. Debunking common misinformation, he offers science-driven strategies in an entertaining, motivating, and easy-to-follow guide to: Improve memory and productivity Increase energy and boost your mood Reduce the risk of anxiety and depression Form healthy habits to supercharge your brain Prevent nongenetic Alzheimer’s and dementia Dr. Milstein arms you with knowledge about common and often overlooked issues that prematurely age the brain (including the surprising truth about what doctors previously got wrong about Alzheimer’s and dementia), and shares a seven-day challenge to help you jump-start new brain-healthy habits. Small changes can make a big difference right away. The Age-Proof Brain will provide the tools you need to ensure that you’re living a happier and more fulfilling life—today, tomorrow, and well into your future.
Download or read book Hypertension and Brain Damage written by Antonio Coca and published by Springer. This book was released on 2018-05-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on diverse aspects of the relationship between hypertension and brain damage, providing up-to-date information that will be of interest to both clinicians and researchers. After an introductory chapter on epidemiology, the significance of various comorbidities that represent risk factors for brain damage in the context of hypertension is discussed. Detailed consideration is then given to the effects of hypertension on small and large cerebral arteries and the consequences for brain damage. Similarly, the association between hypertension and ischemic and hemorrhagic stroke is fully explored, and the evidence and guidelines regarding reduction of high blood pressure during the acute phase of each form of stroke are summarized. Both the primary and the secondary prevention of stroke are addressed, with presentation of the results of key trials. Readers will also find interesting new perspectives on the roles of different imaging techniques, including CT and functional MRI, in detecting and diagnosing brain damage in patients with hypertension. The closing chapters review the relation of hypertension to subjective and objective cognitive failures and to cognitive decline and dementia.
Download or read book Keep Sharp written by Sanjay Gupta and published by Simon and Schuster. This book was released on 2021-01-05 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Keep your brain young, healthy, and sharp with this science-driven guide to protecting your mind from decline by neurosurgeon and CNN chief medical correspondent Dr. Sanjay Gupta. Throughout our life, we look for ways to keep our minds sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers “the book all of us need, young and old” (Walter Isaacson, #1 New York Times bestselling author of The Code Breaker) with insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and mental decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the “must-read owner’s manual” (Arianna Huffington) you’ll need to keep your brain young and healthy regardless of your age!
Download or read book The Teenage Brain written by Frances E. Jensen and published by Harper Collins. This book was released on 2015-01-06 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Bestseller Renowned neurologist Dr. Frances E. Jensen offers a revolutionary look at the brains of teenagers, dispelling myths and offering practical advice for teens, parents and teachers. Dr. Frances E. Jensen is chair of the department of neurology in the Perelman School of Medicine at the University of Pennsylvania. As a mother, teacher, researcher, clinician, and frequent lecturer to parents and teens, she is in a unique position to explain to readers the workings of the teen brain. In The Teenage Brain, Dr. Jensen brings to readers the astonishing findings that previously remained buried in academic journals. The root myth scientists believed for years was that the adolescent brain was essentially an adult one, only with fewer miles on it. Over the last decade, however, the scientific community has learned that the teen years encompass vitally important stages of brain development. Samples of some of the most recent findings include: Teens are better learners than adults because their brain cells more readily "build" memories. But this heightened adaptability can be hijacked by addiction, and the adolescent brain can become addicted more strongly and for a longer duration than the adult brain. Studies show that girls' brains are a full two years more mature than boys' brains in the mid-teens, possibly explaining differences seen in the classroom and in social behavior. Adolescents may not be as resilient to the effects of drugs as we thought. Recent experimental and human studies show that the occasional use of marijuana, for instance, can cause lingering memory problems even days after smoking, and that long-term use of pot impacts later adulthood IQ. Multi-tasking causes divided attention and has been shown to reduce learning ability in the teenage brain. Multi-tasking also has some addictive qualities, which may result in habitual short attention in teenagers. Emotionally stressful situations may impact the adolescent more than it would affect the adult: stress can have permanent effects on mental health and can to lead to higher risk of developing neuropsychiatric disorders such as depression. Dr. Jensen gathers what we’ve discovered about adolescent brain function, wiring, and capacity and explains the science in the contexts of everyday learning and multitasking, stress and memory, sleep, addiction, and decision-making. In this groundbreaking yet accessible book, these findings also yield practical suggestions that will help adults and teenagers negotiate the mysterious world of adolescent development.
Download or read book Brain Protection in Schizophrenia Mood and Cognitive Disorders written by Michael S. Ritsner and published by Springer Science & Business Media. This book was released on 2010-06-16 with total page 661 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection is a novel perspective for the treatment of disorders that lead to neurodegeneration and disabilities as a result of deterioration of neurons due to apoptosis, oxidative stress, excitotoxicity, and other mechanisms. These mechanisms have implications not only for neurodegenerative disorders, but also for schizophrenia, mood and cognitive disorders. The purpose of this book is to provide an up-to-date overview of basic and clinical studies concerning the neuroprotective approach, mechanisms, and several compounds with neuroprotective properties that may contribute to more efficacious treatment of major mental health disorders. The book is divided into two sections. The first section serves as an introduction and overview of conceptual issues of the neuroprotective approach, and some neurobiological advances. Chapters in this section review definitions, perspectives, and issues that provide a conceptual base for the rest of the book. In addition, this part includes chapters in which the authors present and discuss the findings from basic studies of neurodegenerative mechanisms that are associated with the pathogenesis of major mental health disorders. The second section focuses on findings obtained from clinical trials with neuroprotective compounds, and neuromodulatory techniques. The take-home message is that principles of the neuroprotective approach may be applied to treatment of schizophrenia, mood and cognitive disorders. Contributors to this book are among the most active investigators and clinicians in the field who provide new perspectives not only clarifying ongoing controversies but also propose diverse aspects and new insights to neuroprotection. This book is intended for a broad readership, which includes a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, graduate students, and policy makers in the fields of mental health.
