Download or read book Bone Regulators and Osteoporosis Therapy written by Paula H. Stern and published by Springer Nature. This book was released on 2020-11-28 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.
Download or read book The Duration and Safety of Osteoporosis Treatment written by Stuart Silverman and published by Springer. This book was released on 2015-12-29 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive review of short-and long-term adverse events of both antiresorptive and anabolic drugs, this practical guide updates the clinician on the pathophysiology of osteoporosis and the principles behind our present and future pharmaceuticals. Leading practitioners in the field examine all current literature and data regarding the duration and safety of these therapies, with recommendations for clinicians on decision-making and best practices for osteoporosis patients. An overview of the pathophysiology and epidemiology of osteoporosis and discussion of both anabolic and antiresorptive drugs is followed by fracture risk assessment and an examination of treatment failures. Next, a number of chapters are dedicated to the diagnosis, presentation and management of atypical femur fractures and osteonecrosis of the jaw (ONJ), each of which are significant patient concerns when using these osteoporosis treatments. The introduction and utilization of drug holidays is also discussed, as well as the long-term outlook for management of osteoporotic patients. Written and edited by experts in the field, The Duration and Safety of Osteoporosis Treatment is a balanced resource for researchers, practitioners and policy-makers alike for clinical decision-making and patient care.
Download or read book Novel Approaches to Treatment of Osteoporosis written by R.G.G. Russell and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagnosed, often because a fracture has occurred. Treatments in the future will aim at healing osteoporosis by improving bone mass and quality. This book describes novel discoveries and research which will allow bone to be restored after it has been lost.
Download or read book Drug Therapy for Osteoporosis written by Michael Kleerekoper and published by CRC Press. This book was released on 2004-12-02 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hormone replacement is clearly indicated for the prevention and treatment of osteoporosis. Although its importance in treating this disease is no longer questioned, much remains to be fully understood about its effective application in practice. Drug Therapy for Osteoporosis examines what is known about the progress of osteoporosis and describes the impact of hormone replacement therapy. The author reviews the option for using SERMs as opposed to conventional HRT regimens, discusses not only the effectiveness of treatment but also the recommended duration, and provides clear guidelines on the laboratory evaluation of osteoporosis.
Download or read book Osteoporosis Treatment written by Elaine Dennison and published by Springer Nature. This book was released on 2021-08-16 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical overview of osteoporosis for the wide spectrum of clinicians that might encounter the osteoporotic patient. Concise and well-structured chapters examine the public health importance of the condition, the current treatment gap, how to identify individuals who would benefit from treatment, bone turnover and how this can be modified by osteoporosis therapies, adjuvant lifestyle modification, the calcium and vitamin D story, antiresorptive therapies, anabolic therapies, emerging therapies, adherence and compliance with therapy and the perception of fracture risk. Osteoporosis Treatment: A Clinical Overview meets the need for a book that improves awareness of this major public health problem and possible therapeutic approaches. Primary care physicians, endocrinologists, rheumatologists, orthopaedic surgeons and those providing specialist care for the elderly will all benefit from this highly accessible and informative guide to treating osteoporosis.
Download or read book Advances in Osteoporosis written by Yannis Dionyssiotis and published by BoD – Books on Demand. This book was released on 2015-03-04 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: A balanced regulation of bone formation and resorption in the healthy individual is required for a healthy bone. On the other side, there are many factors which can lead to alterations in bone density and microarchitecture. Menopause is a condition which can increase the remodeling process in favor of resorption. Moreover, there are also some diseases, i.e. chronic kidney bone disease, that increase the possibility of fractures and the subsequent disability leading to increased mortality. However, it is clear that drugs are an essential element of the therapy and this issue is analyzed extensively in this book. Some novel pathophysiological mechanisms are also presented, offering advanced knowledge to the reader. The book includes chapters from scientific departments and researchers from all over the world.
Download or read book Anabolic Treatments for Osteoporosis written by James F. Whitfield and published by CRC Press. This book was released on 2013-11-12 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis, a growing epidemic among women in North America, Europe, and Japan, is a painful, costly disease that has presented a treatment challenge to healthcare professionals. Until recently, therapies have focused on agents that slow bone resorption, and have had only limited success at increasing bone mass.
Download or read book Topics in Osteoporosis written by Margarita Valdés-Flores and published by BoD – Books on Demand. This book was released on 2013-05-15 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis affects the osteo-articular system. However, there are hormonal, kidney related, gastrointestinal and neuromuscular factors among other, that can be involved in the etiopathogenesis of the disease. In the other hand, for osteoporosis prevention there are many lifestyle conditions that are very important, as dietary habits, physical activity, drugs and caffeine intake, smoking, associated diseases, etc. Based on the above, treatment and prevention of osteoporosis have to be addressed in a multidisciplinary and integral approach. The knowledge about bone metabolism and the related disorders represents an extensive field that is currently increasing through many investigations conducted in the world. The purpose of this book is to show several reviews and original investigations related with osteoporosis.
Download or read book The Osteoporosis Manual written by Reiner Bartl and published by Springer. This book was released on 2019-02-06 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive manual covers all aspects of the prevention, diagnosis and management of osteoporosis, offering an upbeat and optimistic assessment of what can be achieved. While scientifically based, the book provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. It deals with everything from the basic physiology of bone and mineral metabolism to the diagnostic utility of radiologic imaging and specialized tests and current treatment recommendations, including for fracture management. The relationship of osteoporosis to a variety of other disorders is also thoroughly explored and elucidated. Osteoporosis represents a global threat because every human being is vulnerable to it as time passes. The authors point out the enormous scale of the problem in terms of the human suffering, morbidity, and mortality on the one hand and the associated astronomical national and global costs on the other. Osteoporosis is preventable, and every doctor in every medical discipline can contribute to this goal. And though prevention is better than cure, it is never too late for effective therapy, as outlined in this book. Bone is every doctorʼs and every bodyʼs business!
Download or read book Osteoporosis written by Robert Marcus and published by Academic Press. This book was released on 2007-11-08 with total page 1987 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, Osteoporosis, is the most comprehensive, authoritative reference on this disease. Written by renowned experts in the field, this two-volume reference is a must-have for academic and medical libraries, physicians, researchers, and any company involved in osteoporosis research and development. Worldwide, 200 million women between 60-80 suffer from osteoporosis and have a lifetime risk of fracture between 30 and 40 percent continuing to make osteoporosis a hot topic in medicine. This newest edition covers everything from basic anatomy and physiology to diagnosis, management and treatment in a field where direct care costs for osteoporitic fractures in the U.S. reach up to $18 billion each year. NEW TO THIS EDITION:*Recognizes the critical importance of the Wnt signaling pathway for bone health *Incorporates new chapters on osteocytes, phosphatonins, mouse genetics, and CNS and bone *Examines essential updates on estrogen prevention and treatment and the recent results from the WHI *Discusses the controversial topics of screening and clinical trial design for drug registration *Includes essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, and parathyroid hormone * Offers critical reviews of reproductive and hormonal risk factors, ethnicity, nutrition, therapeutics, management, and economics comprising a tremendous wealth of knowledge in a single source not found elsewhere
Download or read book Osteoporosis Therapy Boning Up on Bones Highlights from the American Society of Bone and Mineral Research Meeting written by Charette, Christine and published by . This book was released on 1997 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Osteoporosis Book written by Nancy E. Lane and published by Oxford University Press. This book was released on 2001-05-31 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoporosis currently affects 25 million people in the United States, and as the baby boomers enter their fifties, this bone-weakening disease is poised to strike millions more. Because of this disease, many older people will suffer from a bone fracture at some point , and far too many of these fractures will result in permanent disability. The good news is that this devastating "silent epidemic" is entirely preventable, and in The Osteoporosis Book, readers of all ages will find everything they need to know to slow, stop, and even reverse the bone loss that causes this crippling disease. Written by Dr. Nancy E. Lane, a leading investigator and clinician in the field of osteoporosis, it is an indispensable guide to the exciting medical breakthroughs that have taken place in the past few years--in bone density measurement, in estrogen therapy, and in our knowledge of the bone cycle--that now allow doctors to predict who is at risk and to monitor these individuals in their fifties, before a fracture occurs. Readers learn to evaluate--and whenever possible, eliminate--the risk factors in their own lives. "What vitamins should I take? Is hormone replacement therapy right for me? And what about exercise?" The answers are here. And for those already affected by osteoporosis, Dr. Lane provides the most effective and up-to-date medical and practical advice available anywhere for coping with its aches and pains and safeguarding against further deterioration. Impeccably researched and reassuringly accessible, The Osteoporosis Book empowers readers to make informed healthcare choices that will enhance the quality of their lives for decades to come. It has been endorsed by the National Osteoporosis Foundation.
Download or read book Osteoporosis written by Eric S. Orwoll and published by Springer Science & Business Media. This book was released on 2002-08-02 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Osteoporosis: Pathophysiology and Clinical Management, leading clinicians and researchers join forces to illuminate in coupled chapters all the major scientific and clinical aspects of osteoporosis. On the basic science side, topics range from the genetics of osteoporosis and bone turnover markers, to androgen action in bone, to the basic biology of estrogen and bone. On the clinical side the authors present the latest thinking about the use of bone densitometry in treatment, the use of vitamin D and its metabolites, and the clinical utilization of salmon calcitonin, as well as parathyroid and bisphosphonate therapies, SERMs, and other important treatments.
Download or read book The Osteoporosis Solution written by Carl Germano and published by Kensington Books. This book was released on 2000-01-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to osteoporosis presents new information on how to prevent and treat the illness, explaining how nutritional therapies can reduce bone loss without detrimental side effects.
Download or read book Pocket Reference to Osteoporosis written by Serge Livio Ferrari and published by Springer. This book was released on 2018-12-28 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book responds to the daily needs of all clinicians treating patients with osteoporosis and provides a key reference guide for any challenges that arise in clinical practice. This book also covers the genetics of the disease, clinical presentation, diagnosis, and current and upcoming treatment recommendations in accordance with the latest international guidelines. Osteoporosis is a disease in which the density and quality of bone are greatly reduced, and as bones become more porous and fragile the risk of fracture increases greatly. It is one of the most common metabolic bone diseases globally with one in three women and one in five men at risk of an osteoporotic fracture, and can result in devastating physical, psychosocial, and economic consequences. However, in spite of this osteoporosis can often be overlooked and undertreated, thus there is a real need to raise awareness of this disease.
Download or read book Osteoporosis in Older Persons written by Gustavo Duque and published by Springer. This book was released on 2016-07-11 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research. It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the first edition of this book, there are few publications about this subject. The first edition of this book demonstrated that there is a need to understand the particular features of osteoporosis in older persons, which is the main aim of this book. The institutions where the authors are affiliated are highly recognized as the main centers in aging bone research. As an innovation, the second edition includes some aspects of muscle and bone interaction focusing of the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. As in the previous edition, this book is expected to be the reference guide for geriatricians, gerontologists, and bone biologists as well as medical trainees in order to understand the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences.
Download or read book Osteoporosis in Older Persons written by Gustavo Duque and published by Springer Science & Business Media. This book was released on 2009-10-13 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book summarizes recent advances in the elucidation of the mechanisms involved in senile osteoporosis as well as its potential treatment, bringing an integrated approach from the bench to the clinical practice. A unique aspect of this book is its emphasis on the application of translational research in the field of osteoporosis and falls. The book provides a complete review on the prevention as well as current and future treatments of osteoporosis.
