Download or read book Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases written by Michel E. Safar and published by Springer. This book was released on 2014-07-30 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: In cardiovascular prevention, there is classically a small number of cardiovascular risk factors to treat, such as hypertension, diabetes, hyperlipidemia and smoking excess, which are widely detected and treated. Recently, it has been widely recognized that new mechanical factors should be detected and treated and involves specifically pulsatile arterial hemodynamic (PAH) parameters such as: arterial stiffness, pulse pressure, and, to a lesser extent, augmentation index and pulse pressure amplification. The pedagogic aspect of this new CV specialty involves 3 principal parts: a. –Basic concepts and pathophysiological mechanisms of PAHb. –Clinical aspects and end-organ damage in PAHc. – Clinical pharmacology and therapeutics of PAH This book represents the first that spans basic science and clinical management of this new CV subspecialty. Much has been learned regarding the management of these patients in recent years and this book presents extensive data on the techniques needed to maximize outcomes.
Download or read book Arterial Stiffness in Hypertension written by Michel Safar and published by Elsevier Health Sciences. This book was released on 2006-04-21 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Main headings: I. Basic concepts of pulsatile arterial hemodynamics. - II. Pathophysiological mechanisms. - III. Arterial stiffness, wave reflections, cardiovascular risk and end-organ damage. - IV. Clinical aspects of arterial stiffness and wave reflections. - V. Therapeutic aspects of arterial stiffness and wave reflections.
Download or read book Pan Vascular Medicine written by Peter Lanzer and published by Springer. This book was released on 2013-12-20 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: The textbook provides an interdisciplinary and integrated perspective of modern vascular cure. Written by experts the text proceeds from fundamental principles to advanced concepts. The book is divided into four parts, each focusing on different basic concepts of vascular cure. All fundamental principles of the area are clearly explained to facilitate vascular diagnostics and treatment in clinical practice. It is aimed at junior practitioners and experts.
Download or read book Pulse Waves written by Paolo Salvi and published by Springer Science & Business Media. This book was released on 2012-04-27 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, several studies have shown the crucial role of viscoelastic properties of the aorta and large arteries in determining blood pressure values. A good knowledge of cardiovascular pathophysiology and vascular hemodynamics is necessary to understand these phenomena. However, available texts on this topic are very complex and difficult for medical practitioners to understand. The aim of this book is to enable the reader to comprehend the relation between cardiovascular pathophysiology and vascular hemodynamics and to become familiar with the more recent guidelines. While very complex physical concepts are involved, care has been taken to ensure that the explanations are as straightforward as possible. Complex analyses are presented separately and can be skipped by the reader without impairment of understanding. It is envisaged that the knowledge imparted will prove invaluable in improving the approach to hypertensive patients.
Download or read book Dynamics of Arterial Flow written by Stewart Wolf and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the edited transcript of the Second Topical Colloquium based on leads developed at the original conference on the artery and the process of arteriosclerosis (the Lindau Conference of 1970). The first follow-up colloquium on "The Smooth Muscle of the Artery" was held in Heidelberg in 1973. Planning for the present one was undertaken by the editors with Dr. C. Forbes Dewey, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts. The meeting itself was held June, 1976 at the Delaware Water Gap, Pennsy1vani~, under the joint sponsorship of Totts Gap Institute and the Massachusetts Institute of Technology with financial support from the American Heart Association, the Office of Naval Research, and the Smith, Kline and French Company. The objective of the series of meetings, beginning at Lindau has been to examine from an interdisciplinary and international point of view the fundamental physiologic and pathophysiologic processes pertinent to the development of arteriosclerosis. This colloquium sought to examine critically the evidence relating hemodynamic forces to atherogenesis, to reconcile disparate findings and interpretations in so far as possible; and to make a synthesis of the present state of knowledge of the dynamics of arterial flow. Grateful acknowledgement is made for the valuable assistance of Joan Martin and Helen Goodell in the entire editorial process. The editors acknowledge with thanks the secretarial assistance of Moira Martin, Colleen Nagle, Cindy Carter and Pat Ide. Special thanks are due Joy Lowe who executed the entire final manuscript.
Download or read book Biology of the Arterial Wall written by Bernard I. Levy and published by Springer Science & Business Media. This book was released on 2007-11-23 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of the Arterial Wall is intended as a general reference text concerned with the biology of the vascular cells and the blood vessel wall under physiological and pathological conditions. One of the major functions of the arteries is to maintain a continuous blood flow to the organs whatever the pressure conditions, thanks to the vasomotor tone of the smooth muscle cells. Great advances have been made over the last decade in the understanding of the endothelial cells as integrators and transducers of signals originating from the blood stream. The pluripotent control functions of the endothelial cells in the vessel wall are now well recognized. A review of endothelial functions and dysfunctions is presented. Cell biology and molecular genetic studies have now identified an array of molecules elaborated by endothelial cells and vascular smooth muscle cells and by the blood-borne elements which interact with artery cells, defending the artery against injury and modulating evolving abnormal processes. Molecules which induce or inhibit endothelial and/or smooth muscle cells are currently under great scrutiny. Angiogenesis, which plays a major role in tumor growth, but may also be beneficial as a healing process in muscle ischemia, is discussed. Apoptosis, or programmed cell death, has only recently been recognized as an essential process in blood vessel modeling and remodeling. An overview of apoptosis in the vascular system is presented. It is increasingly evident that the adjustments of the blood vessel wall are made in the presence of deforming disease processes such as hypertension and atherosclerosis. The second part of the book is concerned with the blood vessel wall in disease conditions. Several chapters review the role of the vessel and vascular cells in inflammation, and vascular remodeling during arterial hypertension and aging. One chapter is devoted to atherogenesis, atheroma and plaque instability, followed by the pathophysiology of post-angioplasty restenosis, which is a crucial issue in modern interventional cardiology.
Download or read book Dynamics Of The Vascular System Interaction With The Heart Second Edition written by John K-j Li and published by World Scientific. This book was released on 2018-09-06 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of the book was written employing mathematical techniques to formulate the physical principles involved in the structural and functional correlates of the underlying physiology.This current and self-contained second edition updates many of the new findings since its first edition a decade ago. It also includes a new chapter on the 'Interaction with the Heart'. The dynamics of the arterial system, the venous system, the microcirculation and their interaction with the heart are quantitatively described in terms of their structures and functions. Clinical measurements, applications to the cardiovascular field and physiological mechanisms are clearly identified throughout the text. Most importantly, worked examples are provided, such that the readers can appreciate the application aspects of the underlying formulation.
Download or read book Cardiovascular Biomechanics written by Peter R. Hoskins and published by Springer. This book was released on 2017-02-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.
Download or read book Studies in blood pressure physiological and clinical written by George Oliver and published by . This book was released on 1908 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Arterial System written by R.D. Bauer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the papers presented at the symposium "Dynamics and Regulation of the Arterial System" held at Erlangen on 28-30 October 1977 in honor of Professor Erik Wetterer. The aim of the symposium was an inten sive exchange of ideas within a mUltidisciplinary group of scientists who are specialists in their fields of research. It is obvious that a two-day symposium covering such a wide range of topics could only highlight certain aspects of the latest research on the cardiovascular system. The book is divided into three sections. The first part deals with arterial hemo dynamics. Emphasized are the mechanical properties of the arterial wall, in particular the smooth muscle, fundamental parameters for the description of pulse wave propagation, such as attenuation, phase velocity, and reflection of pulse waves. Furthermore, new methods for recording arterial diameters and the latest results in determining pulsatile pressure and pulsatile diameter of arteries in vivo as well as from calculations based on models of the arterial system are presented. The second part deals with applications of the control theory and the principles of optimality of the cardiovascular system in toto and of single regions of this system. Contributions to research in the field of regulation of blood volume and of regional hemodynamics are also presented. The third part covers problems of interaction of the heart and the arterial system, including fluid mechanics of the aortic valves and the coronary blood flow under normal and pathologic conditions.
Download or read book The Arterial Circulation written by John K-J Li and published by Springer Science & Business Media. This book was released on 2000-05-05 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: After yet another decade of leaming, experimenting, and inves tigating since my first book, Arterial System Dynamics, the many new medical breakthroughs and technological advances have inspired me to write this book to bridge the gap between basic research and clinical applications. The application of physical principles and quantitative approaches to the understanding of the arterial circulation and its interactions with the heart in normal and diseased conditions form the basis of The Arterial Circulation. Knowledge of the physiology and rheology of arteries, as well as all of their structural-functional corre lates, is a necessary prerequisite to the proper hemodynamic interpretatiqn of pressure-flow relations and the pulsatile transmis sion characteristics in different arteries. The natural coupling and interactions of the heart, the coronary circulation, and the arterial system necessitate analysis of alterations to global functioning. Modeling provides a tool for isolating and predicting parameter changes and is employed throughout the book. Experimental data are provided for model validations, and also for more realistic interpretations. Techniques and new methods for clinical hemo dynamic measurement and diagnosis are included to help the reader un derstand the physical principles underlying such abnormal cardiovascular functions as hypertension, stenosis, and myocardial ischemia. The progressive changes in vascular properties during aging are also discussed. Modem approaches utilizing computer mode ling and allomery are presented with selected examples, such as combined hypertension and aortic valve stenosis, and ventricular hypertrophy.
Download or read book The Arterial System in Hypertension written by Michel Emile Safar and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: MICHEL E. SAFAR and MICHAEL F. O'ROURKE One of the principal problems of hypertension is the precise definition of blood pressure as a cardiovascular risk factor. Clinicians indicate peak systolic pressure and end diastolic pressure in the brachial artery as the principal criteria for blood pressure measurement. Consequently, these values are as indicators for clinical management and therapeutic adjustment. This used methodology, based on indirect blood pressure measurements at the site of the brachial artery relates only to the highest and lowest pressure in that vessel, and does not give any information of the blood pressure curve itself; this carries more information than peak systolic pressure and end diastolic pressure. As a first step in better analysis of the blood pressure curve, research workers in experimental hypertension defined in addition to peak systolic pressure and end diastolic, another blood pressure value, mean arterial pressure, i. e. the average pressure throughout the cardiac cycle, and about which pressure fluctuates. This is the pressure recorded by Hales [1] and by Poiseuille [2] in their pioneering studies. By application of Poiseuille's Law, this definition of mean arterial pressure led to the concept that increased mean arterial pressure (and therefore hypertension) was related, at any given value of cardiac output, to an increase in vascular resistance, i. e. to a reduc tion in the caliber of the small arteries.
Download or read book Arterial system written by Bernard Levy and published by . This book was released on 1978 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comparative Cardiovascular Dynamics of Mammals written by John K-J Li and published by CRC Press. This book was released on 1995-12-05 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comparative Cardiovascular Dynamics of Mammals offers never-before-published data on the structure and function of the circulatory systems of the different mammalian species. This text explores classic allometry, dimensional analysis, and modern hemodynamics to establish similarity principles that provide a necessary and important step in understanding the natural common design and functional features of the cardiovascular systems of different mammals. Fluid and blood vessel mechanics, pulse transmission characteristics, cardiac energetics and mechanics, as well as heart-arterial system interaction are included in this essential reference. The sensitivity of parameters and similarity of principles in the diagnosis of cardiovascular diseases are also addressed. This book also describes the natural processes involved in the functional development of the mammalian cardiovascular system. By using modern methods to present recent findings on the similarities and differences of the mammalian cardiovascular system, the author provides an easily understood approach to this dynamic field of study.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Biofluid Mechanics written by Dieter W. Liepsch and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 2nd International Symposium Biofluid Mechanics and Biorheology. June 25-28, 1989, Munich
Download or read book The Heart in Hypertension written by B. E. Strauer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertensive heart disease is one of the most frequent diseases in man. It is esti mated that there are six to eight million hypertensive patients in the Federal Re public of Germany today. This corresponds with an incidence of 10%-15% in the whole population. Approximately between three and four million show organic eardiac manifestations of hypertension. Of all deaths occurring before the age of 65,30%-40% are attributable to hypertension, and the total morta lity from hypertension is about 20%-25%. Recent epidemiological and clini cal studies have revealed similar figures for other countries, such as the United States and Japan. Hypertensive hypertrophy and cardiac failure are found to be many times more frequent than eardiae hypertrophy and failure of any other origin. Despite the apparent clinical and social importance of the biologieal system "blood pressu re and the heart", data on eardiac performance, on systemic and coronary haemodynamics and on the morphological, bioehemical and contractile proper ti es of ventrieular heart muscle in both experimental and clinical hypertension are rare. This is the reason and stimulus for having organized this symposium, which is the first one coneeming this topie.
