Download or read book Blood Flow Dynamics in Burns written by Robin Mirdell and published by Linköping University Electronic Press. This book was released on 2019-11-25 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objectives: Burns of intermediate thickness are hard to evaluate clinically. This often leads to unnecessary delays of up to 14 days before a surgical decision can be made. To counter this, several objective methods have been developed to determine the healing potential of the wound. Over the years, measurement of perfusion has proven to be the most successful method for evaluation of healing potential. Laser Doppler imaging (LDI) is currently the most used method and can determine surgical need 2 days after injury with an accuracy >90%. There are however emerging techniques like laser speckle contrast imaging (LSCI), which also measure perfusion. LSCI have several advantages over LDI and is easier to use. LSCI can also investigate aspects of the microcirculation, previously not possible with LDI. The aim of this thesis was to investigate LSCI’s ability to evaluate surgical need in burns of indeterminate partial-thickness. The first objective was to investigate the dynamics of perfusion the first 14 days after injury. The purpose was to find the optimal time-window for perfusion measurements. The next goal was to determine the accuracy of different perfusion cut-offs. In this second study, the benefit of a subsequent measurement was also investigated. After this, interobserver variation between different profession groups was studied. Both the agreement of perfusion measurements and observer assessments were evaluated. Finally, cardiac vasomotion in combination with perfusion (pulsatility) was investigated as a method to determine surgical need <48 hours after injury. Methods: Perfusion was measured in a total of 77 patients at the Department of Plastic Surgery, Hand Surgery and Burns at Linköping University Hospital, Sweden. Most of these patients were children and the most common type of burn was scalds. A laser speckle contrast imager (PeriCam PSI System, Perimed AB, Järfälla, Sweden) was used to measure perfusion. Results: In the first paper we showed a clear relation between perfusion dynamics and the healing potential of the wound. The changes in perfusion were largest the first 5 days after injury, why this time interval was selected for subsequent papers. Perfusion measurements done day 3-4 after injury could predict surgical need with a sensitivity of 100% (95% CI: 83.9-100%) and a specificity of 90.4% (95% CI: 83.8-94.9%). If two measurements were used, <24 hours and 3-4 days after injury, the accuracy was 100%. Furthermore, we found that different observers could consistently predict perfusion, while there was a large variation in their clinical assessments. This was not improved by extensive burn experience. Finally, pulsatility could be used to predict surgical need the same day as the injury occurred with a sensitivity of 100% (95% CI: 88.1-100%) and a specificity of 98.8% (95% CI: 95.7- 99.9%). Conclusions: LSCI is a promising method for evaluation of burns and provides several benefits over LDI. The surgical need of burns can be determined mere hours after injury when pulsatility is measured. However, the benefits of early scald diagnostics in children with LSCI need to be evaluated in a prospective study before the method is ready for routine clinical use.
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Download or read book Heat Transfer and Fluid Flow in Biological Processes written by Sid M. Becker and published by Academic Press. This book was released on 2014-12-31 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. - Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology - Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies - Reviews the most recent advances in modeling techniques
Download or read book Chinese Burn Surgery written by Zongcheng Yang and published by Springer. This book was released on 2015-01-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive book in burn surgery, written by 25 experts in China. It summarizes the theoretical basis of and clinical experience in the prevention and control of burn injuries. It is a comprehensive and up-to-date reference book for surgeons and scientists working with burn management. The different degree of burns and surgical techniques during burn wound care, reconstruction and healing are reviewed separately. Authors also introduce successful cases in different kinds of burns.
Download or read book Hot Topics in Burn Injuries written by Selda Pelin Kartal and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to give readers a broad review of burn injuries, which may affect people from birth to death and can lead to high morbidity and mortality. The book consists of four sections and seven chapters. The first section consists of the introductory review chapter, which overviews the burn injuries. The second section includes chapter "Burn Etiology and Pathogenesis," which focuses on burn injuries and clinical findings. The third section consists of chapter "Controlling Inflammation in Burn Injury" and is devoted to the role of inflammatory response, which is fundamental to the healing process, while a prolonged inflammation may lead to scarring and fibrosis. The fourth section consists of four chapters as follows: "Therapeutic Effects of Conservative Treatments on Burn Scars," "Herbal Therapy for Burns and Burn Scars," "Platelet-Rich Plasma in Burn Treatment," and "Surgical Treatment of Burn Scars." The book is easy to read and includes hot topics on burn injury to enhance the reader's understanding and knowledge.
Download or read book Textbook of Aging Skin written by Miranda A. Farage and published by Springer Science & Business Media. This book was released on 2009-12-02 with total page 1255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive ‘Major Reference Book’ compiles all current and latest information on aging skin in a two-volume set. Highly structured with a reader-friendly format, it covers a wide range of areas such as basic sciences, the different diseases and conditions which occur with aging (from malignant to non-malignant), the latest techniques and methods being used such as bioengineering methods and biometrics as well as toxicological and safety considerations for the elderly population. It also illustrates the global consumers’ sociological and psychological implications, ethnicity and gender differences and includes marketing considerations for this elderly group. This unique and comprehensive guide will become the main reference textbook on this topic.
Download or read book Color Atlas of Emergency Trauma written by Demetrios Demetriades and published by Cambridge University Press. This book was released on 2021-06-17 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: This full-color atlas presents over 1200 images from one of the largest trauma centers in North America. Photos, x-rays and illustrations depicting a variety of common and rare traumatic injuries are accompanied by recommendations and advice from a multidisciplinary group of experienced trauma care providers.
Download or read book Microvascular Networks written by Aleksander Popel and published by S. Karger AG (Switzerland). This book was released on 1986 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Industrial Exposure and Control Technologies for OSHA Regulated Hazardous Substances Substances K Z and indices written by and published by . This book was released on 1989 with total page 1166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Biophotonics written by Jürgen Popp and published by John Wiley & Sons. This book was released on 2011-11-30 with total page 1187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new handbook covers the world of biophotonics not only geographically -- with the editors coming from different continents -- but also in terms of content, since the authors come from the whole spectrum of biophotonic basic and applied research. Designed to set the standard for the scientific community, these three volumes break new ground by providing readers with the physics basics as well as the biological and medical background, together with detailed reports on recent technical advances. The Handbook also adopts an application-related approach, starting with the application and then citing the various tools to solve the scientific task, making it of particular value to medical doctors. Divided into several sections, the first part offers introductory chapters on the different fields of research, with subsequent parts focusing on the applications and techniques in various fields of industry and research. The result is a handy source for scientists seeking the basics in a condensed form, and equally a reference for quickly gathering the knowledge from neighboring disciplines. Absolutely invaluable for biophotonic scientists in their daily work.
Download or read book Intra Abdominal Hypertension written by Manu Malbrain and published by Cambridge University Press. This book was released on 2013-08-15 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical clinical handbook reviewing all aspects of the diagnosis and management of intra-abdominal hypertension; essential reading for all critical care staff.
Download or read book Total Burn Care written by David N. Herndon and published by Saunders. This book was released on 2012 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total Burn Care guides you in providing optimal burn care and maximizing recovery, from resuscitation through reconstruction to rehabilitation! Using an integrated, "team" approach, leading authority David N. Herndon, MD, FACS helps you meet the clinical, physical, psychological, and social needs of every patient. With Total Burn Care, you'll offer effective burn management every step of the way! Effectively manage burn patients from their initial presentation through long-term rehabilitation. Devise successful integrated treatment programs for different groups of patients, such as elderly and pediatric patients. Browse the complete contents of Total Burn Care online and download images, tables, figures, PowerPoint presentations, procedural videos, and more at www.expertconsult.com! Decrease mortality from massive burns by applying the latest advances in resuscitation, infection control, early coverage of the burn, and management of smoke inhalation and injury. Enhance burn patients' reintegration into society through expanded sections on reconstructive surgery (with an emphasis on early reconstruction), rehabilitation, occupational and physical therapy, respiratory therapy, and ventilator management.
Download or read book Total Burn Care written by David N. Herndon and published by Elsevier Health Sciences. This book was released on 2007 with total page 893 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using an integrated, "team" approach, leading authority David N. Herndon, MD, FACS explains how to meet the clinical, physical, psychological, and social needs of every burn patient - and thus achieve optimal recovery and rehabilitation. The 3rd Edition of this definitive reference covers all of the latest advances in the treatment of burns...features new a full-color layout with new color illustrations and clinical photographs. Compiled and edited by one of the world's leading authorities on the management of patients with burns. Discusses the management of burn patients from their initial presentation through long-term rehabilitation. Addresses the clinical, physical, and social needs of the burn patient and emphasizes a multi-faceted, "team approach" to treatment. Covers how to devise integrated treatment programs for different groups of patients, such as elderly and pediatric patients. Uses color illustrations and clinical photographs throughout for the first time-incorporating the illustrative strengths of Barret & Herndon's Color Atlas of Burn Care to provide you with a single source of definitive guidance on diagnosis and management. Presents new chapters on barotrauma and inhalation injury - the tissue bank - the role of exercise - and the use of dermal templates and burn scar resurfacing. Offers fresh perspectives from more than 50% new authors. With more than 100 additional contributing experts
Download or read book Handbook of Burns Volume 1 written by Marc G. Jeschke and published by Springer Nature. This book was released on 2019-10-29 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides updated information on acute burn treatment. It also discusses genomic responses to burns and novel techniques in this area. Divided into four topical parts, this book provides insights into the history, epidemiology, prevention of burns, as well as initial and pre-hospital management of burns, acute burn care and therapy, and non-thermal burns. All chapters have been edited by leading world authorities on burn care and offer readers a broad overview of the techniques and outcomes in this area. Please also have a look at "Handbook of Burns Volume 2 - Reconstruction and Rehabilitation 2nd edition".
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1970 with total page 1404 pages. Available in PDF, EPUB and Kindle. Book excerpt: