Download or read book Blastogenesis written by John Marius Optiz and published by Wiley-Liss. This book was released on 1993-10-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of human developmental biology, both normal and abnormal, cannot progress without the alliance of clinical medicine with research in comparative morphology and embryology, teratology, developmental genetics, molecular biology and pathology. Blastogenesis, the developmental stage leading up to uterine implantation, is a particularly important stage of embryogenesis for study because abnormalities of blastogenesis tend to be severe, multiple and frequently lethal, thus affording geneticists and dysmorphologists an opportunity to study genetic defects in early development. In this work, an international group of human and medical geneticists, human developmental biologists and dysmorphologists present results of molecular, chromosomal, morphological and clinical studies.
Download or read book Embryo and Fetal Pathology written by Enid Gilbert-Barness and published by Cambridge University Press. This book was released on 2004-05-31 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exhaustively illustrated in color with over 1000 photographs, figures, histopathology slides, and sonographs, this uniquely authoritative atlas provides the clinician with a visual guide to diagnosing congenital anomalies, both common and rare, in every organ system in the human fetus. It covers the full range of embryo and fetal pathology, from point of death, autopsy and ultrasound, through specific syndromes, intrauterine problems, organ and system defects to multiple births and conjoined twins. Gross pathologic findings are correlated with sonographic features in order that the reader may confirm visually the diagnosis of congenital abnormalities for all organ systems. Obstetricians, perinatologists, neonatologists, geneticists, anatomic pathologists, and all practitioners of maternal-fetal medicine will find this atlas an invaluable resource.
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1998 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Biology and Immunology of Leukocyte Function written by Efraim Racker and published by Elsevier. This book was released on 2012-12-02 with total page 990 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Biology and Immunology of Leukocyte Function is a collection of papers presented at the 12th International Leukocyte Culture Conference, held in Beersheba, Israel on June 1978. This book is organized into seven parts encompassing 111 chapters. The contributors cover the different aspects of cell biology and immunology and the unique leukocyte function. Part I describes the mechanism of lymphocyte activation, the structure and function of the plasma membrane, and the macromolecular synthesis during lymphocyte activation. This part also deals with the interaction of lymphocytes with mitogenic lectins, the comparison of the mitogenic and nonmitogenic lectin binding, and the role of macrophages in the response of lymphocytes to lectins. Part II explores the thymic factors and the development of characteristic markers, antigens, and receptors. This part particularly emphasizes lymphocyte differentiation. Parts III and IV examine the genetic control and intercellular interactions involved in leukocyte function and the parameters of the immune response under in vitro conditions. Chapters on cytotoxicity, the mechanisms of phagocytic killing, autoimmunity, and the responses of leukocytes to tumor cells are included in these parts. Part V discusses the interactions of viruses and leukocytes and provides data on the physical mapping and analysis of sarcoma and leukemia viruses, while Part VI considers the application of leukocyte culture to problems of clinical medicine. Part VII involves the study of radiation effects, with an emphasis on the application of total lymphoid irradiation to the induction of transplantation tolerance. This part also looks into the role of the DNA repair process. Cell biologists, immunologists, and biomedical scientists and researchers will greatly benefit from this book.
Download or read book Melanoma Antigens and Antibodies written by Ralph A. Reisfeld and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ever-expanding research on human cancer has resulted in numerous technical and conceptual advances during the last few years. Serological, structural, and biological char acterization of human melanoma constitutes one area of research that has received consid erable attention from researchers and clinicians and has generated new and exciting infor mation. In this volume, we have attempted to assemble work on topics that produced some of the most recent advances. We asked each author to describe and interpret his most cur rent research and, whenever possible, to compare and contrast it with work of other inves tigators in the field. We have been careful not to impose our viewpoints except in contri butions from our own laboratories, since we want to provide the reader with as many divergent and sometimes opposing viewpoints as feasible. Therefore, we have not been overly concerned with overlaps in some individual topics. We hope that this volume will provide the reader with a well-balanced overview of current problems and ideas in a par ticular area of cancer research. We wish to express our thanks to all contributors for their timely and very interesting manuscripts, and we sincerely hope that the reader will enjoy this volume and benefit as much from it as we did. R. A. Reisfeld S. Ferrone La Jolla ix Contents CHAPTER 1 Immunogenetics of Melanoma RONALD T. ACTON, CHARLES M. BALCH, BRUCE BUDOWLE, RODNEY C. P. Go, JEFFREY M. ROSEMAN, SENG-jAW SOONG, AND BRUCE O. BARGER 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Download or read book Immunotoxicology And Immunopharmacology written by H Dean Jack and published by CRC Press. This book was released on 1994-06-30 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this text has been revised and refocused to reflect the transformation of immunotoxicology from a subdiscipline of toxicology to an independent area of research that can best be described as "environmental immunology." New chapters discuss the role of immune mediators in liver, lung, and skin toxicity, in regulating chemical- metabolizing enzymes, and in the immunosuppression produced by ultraviolet light. More emphasis is placed on the clinical consequences of immunotoxicity, as well as the interpretation of experimental data for predicting, human health risk.; The second edition is divided into three major sections: immunosuppression, autoimmunity, and hypersensitivity. This new organization of the text allows for a more thorough treatment of these phenomena, with greater attention to test methods, theoretical considerations, and clinical implications. The book includes many chapters on specific environmental agents, therapeutic drugs, biological agents, and drugs of abuse, as well as on immune-mediated toxicity in specific organ systems.
Download or read book Metal Ions in Biological Systems written by Helmut Sigel and published by CRC Press. This book was released on 1983-09-29 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cadmium written by Ernest C. Foulkes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The toxic properties of cadmium compounds have been well recognized in many species. There is little evidence to suggest a physiologic role for the metal. Rather, because of its long biologic half-life, cadmium acts as a cumulative poison, and even at quite low ambient concentrations, it can accumulate in mammals to values not insignificant in terms of critical toxic levels. The problem of cadmium toxicity has become especially important, as cadmium concentrations in the environment have begun to rise owing to a variety of human activities such as mining, the metallurgical industry, coal combustion, and the use of cadmium-containing fertilizers. It seemed appropriate, therefore, to assemble in one volume an up-to-date analysis of the mechanism of action of cadmium on biologic systems. Aspects of this field have repeatedly been reviewed in the past, and particular reference must be made to the volumes prepared by FRIBERG and collaborators from Sweden. Much outstanding work on cadmium has also been reported from Japan, and I am happy that investigators from both countries were able to contribute to the present volume. Obviously, this volume does not report a consensus by its contributors. The purpose of the work was to permit leading investigators in the field to present a critical review with sufficient documentation to support their interpretations and conclusions. A certain amount of overlap and disagreement between chapters was therefore unavoidable. The result, I hope, will be a useful state-of-the-art discussion.
Download or read book Prevention of Kidney Disease and Long Term Survival written by Morrell M. Avram and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Renal Failure Prevention and Treatment in the 19808 It appears logical to juxtapose in this volume prevention-low cost and nonmorbid-with uremia therapy, which is very morbid and very high cost. Treated uremic patients constitute an important, complex, and demanding group of survivors of a formerly universally fatal disease. Throughout the developed nations of the world, an increasing fraction of the health care budget is devoted to sustaining lives by dialytic therapy and renal transplantation. In the United States, for example, patients in renal failure comprise 0.2% of those eligible for support by Medicare, but consume 5.0% of the Medicare budget. Economic stresses in funding kidney patients have, in some countries such as Great Britain, forced a return to restrictive selection policies abhorrent to empathetic physicians. For third world residents, attention to nutrition, sanitation, and infections such as malaria must take a higher priority than costly uremia therapy. Thus the solution of one problem (retarding death from uremia) created several equally vexing other dilemmas (who should be treated and at what cost?). While sociologists, economists, and ethicists struggle with the new field of psychonephrology,1 a group of investigators and clinicians convened to examine medical aspects of long-surviving treated uremic patients. These proceedings represent the first American analyis of those unique patients who have lived for ten or more years beyond what would have formerly been certain death in uremia.
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Morphogenesis written by M. Abercrombie and published by Academic Press. This book was released on 2013-10-22 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in morphogenesis, Volume 7 considers the significant advances in various aspects of morphogenesis. This volume is composed of eight chapters that specifically cover the concept of blastogenesis and tissue regeneration. The introductory chapter presents the evidence suggesting that the mechanism involved in the initiation of growth in compensatory hypertrophy may not be the same as that in wound healing. The succeeding two chapters deal with certain morphogenetic aspects of the crown gall problem and the development of the innervation of the tetrapod limb by combined observations of behavior with histological studies. These topics are followed by discussions on the synthesis of mRNA during embryonic development, aspects of blastogenesis, and phases of amphibian limb regeneration. The concluding chapters examine the main features of the induction of the development of kidney tubules in the metanephrogenic mesenchyme and the utilization of the developing Fucus egg as a prototype of the localization phenomenon. This book is directed primarily toward developmental biologists.
Download or read book Experimental and Clinical Effects of L Asparaginase written by E. Grundmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Potter s Pathology of the Fetus and Infant E Book written by Enid Gilbert-Barness and published by Elsevier Health Sciences. This book was released on 2007-05-01 with total page 2345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference addresses all aspects of fetal and neonatal pathology, including complicated pregnancies, multiple pregnancies, abortion, placental pathology, and disorders affecting the full-term neonate. A consistent organization allows for quick access to specific guidance, and nearly 2,500 illustrations - 2,350 in full color - depict conditions and abnormalities as they present in practice, facilitating diagnosis. An Image Bank on CD-ROM - new to this edition - features all of the illustrations from the 2-volume set, downloadable for presentations. - Offers comprehensive coverage of all common and rare embryonic, fetal, and infant disorders in one source. - Correlates clinical, pathologic, and genetic findings for each systemic disease. - Emphasizes the genetic and molecular basis of birth defects.Features nearly 2,500 illustrations - 2,350 in full color - which depict each abnormality or condition as they present in practice. - Presents practical information on autopsy techniques and protocols.Provides the latest guidance on molecular pathology, immunohistochemistry, DNA technology, and more. - Offers an expanded discussion of developmental biology related to the pathogenesis of birth defects. - Features user-friendly summary tables and diagnostic flow charts, making information quick and easy to find. - Includes a CD-ROM featuring all of the illustrations from the 2-volume set.
Download or read book Immunological Aspects of Cancer written by J.E. Castro and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: An immunological approach to the treatment of cancer has many theoretical features to commend it. There should be specificity, so that tumour cells alone are destroyed whilst normal tissues are unaffected. Provided the tumour is uni form and all of the cells have appropriate antigens, every malignant cell should be destroyed and even distant metastases dealt with. So far these speculative advantages are unfulfilled and the initial optimism that surrounded im munotherapy has not been sustained. Acceptance of the precepts of tumour im munology continues but these disappointing observations had led to increasing scrutiny of certain aspects. The purpose of this chapter is to review the prin ciples which underly tumour immunology and immunotherapy, so that the more detailed studies that follow can be considered in perspective. TUMOUR ANTIGENS (Chapter 2) For a tumour to initiate an immunological response, it must possess distinctive antigens. Much of the early work in tumour immunity was confused because it was not appreciated that tumours, like other tissues, exhibit transplan tation antigens. Only when syngeneic tumours are used can tumour antigens alone be studied and it was the introduction of inbred mouse strains which allowed Foley in 1953' to produce the first evidence for specific an tigenicity of experimental tumours. Demonstration of these antigens requires that pretreatment with syngeneic tumour will influence the growth of a sub sequent challenge with the same neoplastic cells.
Download or read book Leukocyte Membrane Determinants Regulating Immune Reactivity written by Vincent P. Eijsvoogel and published by Elsevier. This book was released on 2012-12-02 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leukocyte Membrane Determinants Regulating Immune Reactivity is a result of the Leukocyte Culture Conference meeting held at Amsterdam in 1975. Abstracts presented in the meeting are compiled in this book. The topics of these abstracts are all under leukocyte biology and include not just lymphocytes but also monocytes, macrophages, and granulocytes. The text is composed of six major sections. The first section features abstracts that deal with ligand binding and subsequent changes in membrane. Section II focuses on the receptors on lymphocytes in the context of various subpopulations. Immune reactivity, specifically its augmentation or suppression, is the main topic of Section III. Gene products are emphasized in Section IV, while effector functions of membrane determinants are tackled in Section V. Finally, Section VI features leukocyte membrane determinants in differentiation and maturation. The book presents much detailed information that will be of great help to students or professionals in the study of biology, specifically leukocyte biology.
Download or read book NCRP Report written by National Council on Radiation Protection and Measurements and published by . This book was released on 1966 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal of Animal Science written by and published by . This book was released on 1987 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
