Download or read book Biosensors for Single Cell Analysis written by Jian Chen and published by Academic Press. This book was released on 2021-10-26 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers. Includes chapters focused on key single-cell properties, such as proteomic, metabolic and mechanical characterization Features case studies that illustrate the application of biosensors for single-cell analysis Considers microfluidic approaches for each single-cell property discussed Explores future directions for single-cell analysis and biosensor technology
Download or read book Handbook of Biosensors and Biosensor Kinetics written by Ajit Sadana and published by Elsevier. This book was released on 2010-08-26 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are essential to an ever-expanding range of applications, including healthcare; drug design; detection of biological, chemical, and toxic agents; environmental monitoring; biotechnology; aviation; physics; oceanography; and the protection of civilian and engineering infrastructures. This book, like the previous five books on biosensors by this author (and one by the co-author), addresses the neglected areas of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces. Topics are covered in a comprehensive fashion, with homogeneous presentation for the benefit of the reader. The contributors address the economic aspects of biosensors and incorporate coverage of biosensor fabrication and nanobiosensors, among other topics. The comments, comparison, and discussion presented provides a better perspective of where the field of biosensors is heading. Serves as a comprehensive resource on biosensor analysis Examines timely topics such as biosensor fabrication and nanobiosensors Covers economic aspects and medical applications (e.g., the role of analytes in controlling diabetes)
Download or read book Electrochemical Sensors Biosensors and their Biomedical Applications written by Xueji Zhang and published by Academic Press. This book was released on 2011-04-28 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future. This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors
Download or read book Single Cell Analysis written by Dario Anselmetti and published by John Wiley & Sons. This book was released on 2009-03-09 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application areas, from microscopy and spectroscopy to proteomics and microfluidics.
Download or read book Single Cell Analysis written by Tuhin Subhra Santra and published by MDPI. This book was released on 2021-06-02 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cells are the most fundamental building block of all living organisms. The investigation of any type of disease mechanism and its progression still remains challenging due to cellular heterogeneity characteristics and physiological state of cells in a given population. The bulk measurement of millions of cells together can provide some general information on cells, but it cannot evolve the cellular heterogeneity and molecular dynamics in a certain cell population. Compared to this bulk or the average measurement of a large number of cells together, single-cell analysis can provide detailed information on each cell, which could assist in developing an understanding of the specific biological context of cells, such as tumor progression or issues around stem cells. Single-cell omics can provide valuable information about functional mutation and a copy number of variations of cells. Information from single-cell investigations can help to produce a better understanding of intracellular interactions and environmental responses of cellular organelles, which can be beneficial for therapeutics development and diagnostics purposes. This Special Issue is inviting articles related to single-cell analysis and its advantages, limitations, and future prospects regarding health benefits.
Download or read book Microfluidics for Single Cell Analysis written by Jin-Ming Lin and published by Springer Nature. This book was released on 2019-08-28 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.
Download or read book Development Application and Characterization of a Single Cell Based Sensor written by Shalini Prasad and published by . This book was released on 2004 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Essentials of Single Cell Analysis written by Fan-Gang Tseng and published by Springer. This book was released on 2016-01-21 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in academia and professionals in industry working on different aspects of single-cell analysis. Dr. Fan-Gang Tseng is a Distinguished Professor of Engineering and System Science at the National Tsing Hua University, Taiwan. Dr. Tuhin Subhra Santra is a Research Associate at the California Nano Systems Institute, University of California at Los Angeles, USA.
Download or read book Single Cell Analysis in Biotechnology and Systems Biology written by Fan-Gang Tseng and published by MDPI. This book was released on 2018-10-01 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Single Cell Analysis in Biotechnology and Systems Biology" that was published in IJMS
Download or read book Cell Analysis on Microfluidics written by Jin-Ming Lin and published by Springer. This book was released on 2017-10-25 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.
Download or read book Single Cell Omics written by Debmalya Barh and published by Academic Press. This book was released on 2019-06-06 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis. Covers not only the technological aspects, but also the diverse applications of single cell omics in the biomedical field Summarizes the latest progress in single cell omics and discusses potential future developments for research and diagnosis Written by experts across the world, bringing different points-of-view and case studies to give a comprehensive overview on the topic
Download or read book Biosensors written by and published by BoD – Books on Demand. This book was released on 2021-05-05 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers novel and current strategies for biosensing, from the use of nanomaterials and biological functionalized surfaces to the mathematical assessment of novel biosensors and their potential use as wearable devices for continuous monitoring. Biosensing technologies can be used in the medical field for the early detection of disease, monitoring effectiveness of treatments, detecting nervous system signals for controlling robotic prosthesis, and much more. This book includes eleven chapters that examine and discuss several strategies of biosensing, proposing mathematical designs that address the latest reported technologies.
Download or read book Microfluidics and Nanotechnology written by Eric Lagally and published by CRC Press. This book was released on 2017-12-19 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: An increasing number of technologies are being used to detect minute quantities of biomolecules and cells. However, it can be difficult to determine which technologies show the most promise for high-sensitivity and low-limit detection in different applications. Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single molecules—approaches employed by the world’s foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemical—as well as contact and noncontact—detection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state of the art, the text: Explains the theory behind different detection techniques, from mechanical resonators for detecting cell density to fiber-optic methods for detecting DNA hybridization, and beyond Examines microfluidic advances, including droplet microfluidics, digital microfluidics for manipulating droplets on the microscale, and more Highlights an array of technologies to allow for a comparison of the fundamental advantages and challenges of each, as well as an appreciation of the power of leveraging scalability and integration to achieve sensitivity at low cost Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit not only serves as a quick reference for the latest achievements in biochemical detection at the single-cell and single-molecule levels, but also provides researchers with inspiration for further innovation and expansion of the field.
Download or read book Nanotechnology in Biology and Medicine written by Tuan Vo-Dinh and published by CRC Press. This book was released on 2017-10-03 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.
Download or read book Emerging Tools for Single Cell Analysis written by Gary Durack and published by John Wiley & Sons. This book was released on 2004-03-24 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resurgence of interest in high-resolution evaluation of single-cell properties has led to examining where current technology stands at the beginning of a new millennium. Engineers and scientists have produced significant advances in cytometric technologies in just the past few years. Emerging Tools for Single-Cell Analysis: Advances in Optical Measurement Technologies stresses the applications and theories behind some of these advances in cell measurement and cell- sorting technologies. Rapid assessment of the proper function of cells and molecular processes within cells is essential. To that end, new and varying technologies present important diagnostic and prognostic tools relevant to a variety of diseases. Future developments in miniaturization of electronics, micro- and nanomachines, and biomedical engineering are certain to impact cell biology. New analytical technologies are revolutionizing our ability to functionally characterize, isolate, and manipulate single cells. This timely book offers researchers and design engineers much-needed information as they further develop technologies for cell analysis. By comparing and contrasting various approaches, the authors explain how those technologies converge toward similar goals: evaluating the properties of cells and sorting cells on those properties using optically-based measurement systems. Emerging Tools for Single-Cell Analysis offers scientists and engineers a vision of the exciting possibilities that exist as new technologies are applied to single-cell analysis,
Download or read book Microfluidic Biosensors written by Wing Cheung Mak and published by Elsevier. This book was released on 2022-11-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microfluidic Biosensors provides a comprehensive overview covering the most recent emerging technologies on the design, fabrication, and integration of microfluidics with transducers. These form various integrated microfluidic biosensors with device configurations ranging from 2D to 4D levels. Coverage also includes advanced printed microfluidic biosensors, flexible microfluidics for wearable biosensors, autonomous lab-on-a-chip biosensors, CMOS-base microanalysis systems, and microfluidic devices for mobile phone biosensing. The editors and contributors of this book represent both academia and industry, come from a varied range of backgrounds, and offer a global perspective. This book discusses the design and principle of microfluidic systems and uses them for biosensing applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, providing a unique perspective and much-needed content. The editors have crafted this book to be accessible to all levels of academics from graduate students, researchers, and professors working in the fields of biosensors, microfluidics design, material science, analytical chemistry, biomedical devices, and biomedical engineering. It can also be useful for industry professionals working for microfluidic device manufacturers, or in the industry of biosensors and biomedical devices. Presents an in-depth overview of microfluidic biosensors and associated emerging technologies such as printed microfluidics and novel transducers Addresses a range of microfluidic biosensors with device configurations ranging from 2D to 4D levels Includes the commercialization aspects of microfluidic biosensors that provide insights for scientists and engineers in research and development
Download or read book Biosensors and Cancer written by Victor R. Preedy and published by CRC Press. This book was released on 2012-07-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the importance and application of biosensors is complicated by the diverse range of methods and applications. Furthermore, existing texts are somewhat technical in nature, making it difficult for the novice. This book disseminates information on biosensors in a readable way, suitable to a wide audience with varying levels of experience. Topics include optical imaging, surface plasmon resonance, microcantilevers, electrochemistry, aptamers, fluorescence, electrochemistry, nanobiosensors, and nanowires.
