Download or read book Fundamentals of Modern Bioprocessing written by Sarfaraz K. Niazi and published by CRC Press. This book was released on 2017-07-27 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.

Download or read book Ultrafiltration for Bioprocessing written by Herb Lutz and published by Elsevier. This book was released on 2015-02-17 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrafiltration for Bioprocessing is key reading for all those involved in the biotechnology and biopharmaceutical areas. Written by a leading worker in the area, it includes many practical applications and case studies in the key process of ultrafiltration (UF), which is used in almost every bioprocess. Focuses on ultrafiltration for biopharmaceuticals—other books look at general ultrafiltration or general biopharmaceuticals A mix of theory and practical applications—other books tend to be more theory-oriented Addresses the main issues encountered in development and scale-up through recommendations and case studies

Download or read book Bioprocessing for Biomolecules Production written by Gustavo Molina and published by John Wiley & Sons. This book was released on 2020-01-21 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the many recent innovations and advancements in the field of biotechnological processes This book tackles the challenges and potential of biotechnological processes for the production of new industrial ingredients, bioactive compounds, biopolymers, energy sources, and compounds with commercial/industrial and economic interest by performing an interface between the developments achieved in the recent worldwide research and its many challenges to the upscale process until the adoption of commercial as well as industrial scale. Bioprocessing for Biomolecules Production examines the current status of the use and limitation of biotechnology in different industrial sectors, prospects for development combined with advances in technology and investment, and intellectual and technical production around worldwide research. It also covers new regulatory bodies, laws and regulations, and more. Chapters look at biological and biotechnological processes in the food, pharmaceutical, and biofuel industries; research and production of microbial PUFAs; organic acids and their potential for industry; second and third generation biofuels; the fermentative production of beta-glucan; and extremophiles for hydrolytic enzymes productions. The book also looks at bioethanol production from fruit and vegetable wastes; bioprocessing of cassava stem to bioethanol using soaking in aqueous ammonia pretreatment; bioprospecting of microbes for bio-hydrogen production; and more. Provides up to date information about the advancements made on the production of important biotechnological ingredients Complete visualization of the general developments of world research around diverse products and ingredients of technological, economic, commercial and social importance Investigates the use and recovery of agro-industrial wastes in biotechnological processes Includes the latest updates from regulatory bodies for commercialization feasibility Offering new products and techniques for the industrial development and diversification of commercial products, Bioprocessing for Biomolecules Production is an important book for graduate students, professionals, and researchers involved in food technology, biotechnology; microbiology, bioengineering, biochemistry, and enzymology.

Download or read book Bioprocessing for Value Added Products from Renewable Resources written by Shang-Tian Yang and published by Elsevier. This book was released on 2011-08-11 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Elsevier. This book was released on 1995-04-03 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists. This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems. * * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists * Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems * Comprehensive, single-authored * 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems * 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors * Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading * Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used * Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.

Download or read book Biopharmaceutical Processing written by Gunter Jagschies and published by Elsevier. This book was released on 2018-01-18 with total page 1308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. Offers a comprehensive, go-to reference for daily work decisions Covers both upstream and downstream processes Includes case studies that emphasize financial outcomes Presents summaries, decision grids, graphs and overviews for quick reference

Download or read book Bioprocessing Safety written by Warren C. Hyer and published by ASTM International. This book was released on 1990 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Food and Industrial Bioproducts and Bioprocessing written by Nurhan Turgut Dunford and published by John Wiley & Sons. This book was released on 2012-05-01 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food and Industrial Bioproducts and Bioprocessing describes the engineering aspects of bioprocessing, including advanced food processing techniques and bioproduct development. The main focus of the book is on food applications, while numerous industrial applications are highlighted as well. The editors and authors, all experts in various bioprocessing fields, cover the latest developments in the industry and provide perspective on new and potential products and processes. Challenges and opportunities facing the bioproduct manufacturing industry are also discussed. Coverage is far-reaching and includes: current and future biomass sources and bioprocesses; oilseed processing and refining; starch and protein processing; non-thermal food processing; fermentation; extraction techniques; enzymatic conversions; nanotechnology; microencapsulation and emulsion techniques; bioproducts from fungi and algae; biopolymers; and biodegradable/edible packaging. Researchers and product developers in food science, agriculture, engineering, bioprocessing and bioproduct development will find Food and Industrial Bioproducts and Bioprocessing an invaluable resource.

Download or read book Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts written by Claire Komives and published by John Wiley & Sons. This book was released on 2018-12-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies

Download or read book Bioprocessing for Cell Based Therapies written by Che J. Connon and published by John Wiley & Sons. This book was released on 2017-02-06 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from leading, international academics and industrial practitioners, Bioprocessing for Cell-Based Therapies explores the very latest techniques and guidelines in bioprocess production to meet safety, regulatory and ethical requirements, for the production of therapeutic cells, including stem cells. An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout In depth discussion of the application of cell therapy including methods used in the delivery of cells to the patient Includes contributions from experts in both academia and industry, combining a practical approach with cutting edge research The only handbook currently available to provide a state of the art guide to Bioprocessing covering the complete range of cell-based therapies, from experts in academia and industry

Download or read book PAT Applied in Biopharmaceutical Process Development And Manufacturing written by Cenk Undey and published by CRC Press. This book was released on 2011-12-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH). Given the rapid growth in the biopharmaceutical area and the complexity of the molecules, the optimum use of which are still being developed, there is a great need for flexible and proactive teams in order to satisfy the regulatory requirements during process development. Process Analytical Technologies (PAT) applied in biopharmaceutical process development and manufacturing have received significant attention in recent years as an enabler to the QbD paradigm. PAT Applied in Biopharmaceutical Process Development and Manufacturing covers technological advances in measurement sciences, data acquisition, monitoring, and control. Technical leaders present real-life case studies in areas including measuring and monitoring raw materials, cell culture, purification, and cleaning and lyophilization processes via advanced PAT. They also explore how data are collected and analyzed using advanced analytical techniques such as multivariate data analysis, monitoring, and control in real-time. Invaluable for experienced practitioners in PAT in biopharmaceuticals, this book is an excellent reference guide for regulatory officials and a vital training aid for students who need to learn the state of the art in this interdisciplinary and exciting area.

Download or read book Advanced Bioprocessing for Alternative Fuels Biobased Chemicals and Bioproducts written by Majid Hosseini and published by Academic Press. This book was released on 2019-02-23 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Bioprocessing for Alternative Fuels, Bio-based Chemicals, and Bioproducts: Technologies and Approaches for Scale-Up and Commercialization demonstrates novel systems that apply advanced bioprocessing technologies to produce biofuels, bio-based chemicals, and value-added bioproducts from renewable sources. The book presents the use of novel oleaginous microorganisms and utilization strategies for applications of advanced bioprocessing technology in biofuels production and thoroughly depicts the technological breakthroughs of value added bioproducts. It also aides in the design, evaluation and production of biofuels by describing metabolic engineering and genetic manipulation of biofuels feedstocks. Users will find a thorough overview of the most recent discoveries in biofuels research and the inherent challenges associated with scale up. Emphasis is placed on technological milestones and breakthroughs in applications of new bioprocessing technologies for biofuels production. Its essential information can be used to understand how to incorporate advanced bioprocessing technologies into the scaling up of laboratory technologies to industrial applications while complying with biofuels policies and regulations. Presents the use of novel oleaginous microorganisms and utilization strategies for the applications of advanced technologies in biofuels production Provides a basis for technology assessments, progress and advances, as well as the challenges associated with biofuels at industrial scale Describes, in detail, technologies for metabolic engineering and genetic manipulation of biofuels feedstocks, thus aiding in the design, evaluation and production of advanced biofuels

Download or read book Bioprocess Engineering written by Pau Loke Show and published by CRC Press. This book was released on 2019-05-24 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Download or read book Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels Chemicals and Polymers written by Shang-Tian Yang and published by John Wiley & Sons. This book was released on 2013-05-24 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sets the stage for large-scale production of biofuels and bio-based chemicals In response to diminishing supplies as well as the environmental hazards posed by fossil fuels and petrochemicals, interest and demand for green, sustainable biofuels and bio-based chemicals are soaring. Biomass may be the solution. It is an abundant carbon-neutral renewable feedstock that can be used for the production of fuels and chemicals. Currently, biorefineries use corn, soybeans, and sugarcane for bioethanol and biodiesel production; however, there are many challenges facing biorefineries, preventing biomass from reaching its full potential. This book provides a comprehensive review of bioprocessing technologies that use lignocellulosic biomass for the production of biofuels, biochemicals, and biopolymers. It begins with an overview of integrated biorefineries. Next, it covers: Biomass feedstocks, including sugar, starch, oil, and energy crops as well as microalgae Pretreatment technologies for lignocellulosic biomass Hydrolytic enzymes used in biorefineries for the hydrolysis of starch and lignocelluloses Bioconversion technologies for current and future biofuels such as ethanol, biodiesel, butanol, hydrogen, and biogas Specialty chemicals, building block chemicals, and biopolymers produced via fermentation Phytochemicals and functional food ingredients extracted from plant materials All the chapters have been written and edited by leading experts in bioprocessing and biorefining technologies. Contributions are based on a thorough review of the literature as well as the authors' firsthand experience developing and working with bioprocessing technologies. By setting forth the current state of the technology and pointing to promising new directions in research, Bioprocessing Technologies in Biorefinery for Sustainable Production of Fuels, Chemicals, and Polymers will enable readers to move towards large-scale, sustainable, and economical production of biofuels and bio-based chemicals.

Download or read book Nanomaterials for Bioreactors and Bioprocessing Applications written by Guillermo R. Castro and published by Elsevier. This book was released on 2023-06-06 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Bioreactors and Bioprocessing Applications explores the potential of nanomaterials in improving the efficiency of bioprocessing industries and next-generation bioreactors. The book provides information on various newly synthesized nanomaterials in bioreactors for scaling up the bioprocess to an industrial level, the criteria and properties of nanomaterials to be used in bioprocessing, advantages and challenges while using the nanomaterials, and economic constraints. In addition, the book also discusses the fate of various nanomaterials in the bioprocess, the chances of product contamination, and its prevention. This book is an important reference source for materials scientists and biomedical engineers seeking information on the synthesized nanomaterials that are available for bioreactors and bioprocesses, and the various optimized conditions and precautions to be taken. Explores the potential of nanomaterials in improving the efficiency of bioprocessing industries and next-generation bioreactors Provides information on various newly synthesized nanomaterials in bioreactors Discusses the fate of various nanomaterials in the bioprocess, the chances of product contamination, and its prevention

Download or read book Biochemical and Environmental Bioprocessing written by M Jerold and published by CRC Press. This book was released on 2019-07-25 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid growth of industries has resulted in the generation of high volume of solid and liquid waste. Today, there is a need of Clean and Green technology for the sustainable waste management. Biochemical and Environmental Bioprocessing: Challenges and Developments explore the State-of-art green technologies to manage the waste and to recover value added products. Microbes play an important role in the bioremediation. Bioprocess engineering an interdisciplinary connects the Science and Technology. The bioconversion and bioremediation is essentially required for the management of various hazardous substances in the environment. This book will give an intensive knowledge on the application of Biochemical and Bioprocess technologies for the eco-friendly management of pollution. This book serves as a fundamental to the students, researchers, academicians and Engineers working in the area of Environmental Bioremediation and in the exploration of various bioproducts from waste. Features Reviews various biological methods for the treatment of effluents from Industries by using biomass and biopolymers. Highlights the applications of various bioreactors like Anaerobic Sequential Batch Reactor, Continuously stirred anaerobic digester, Up-flow anaerobic sludge blanket reactor, Fluidized and expanded bed reactors. Presents the cultivation of algae in Open Pond, Closed loop System, and Photo-bioreactors for bioenergy production. Discusses the intensified and integrated biorefinery approach by Microwave Irradiation, Pyrolysis, Acoustic cavitation, Hydrodynamic cavitation, Electron beam irradiation, High pressure Autoclave reactor, Steam explosion and photochemical oxidation. Outlines the usage of microbial fuel cell (MFC) for the production bioelectricity generation in different modules Tubular MFC, Stacked MFC, Separate electrode modules Cutting edge research of synthesis of biogenic nanoparticles and Pigments by green route for the health care and environment management.

Download or read book Control in Bioprocessing written by Pablo A. López Pérez and published by John Wiley & Sons. This book was released on 2020-03-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing "quality" of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses.