Download or read book Biomechanical Evaluation of Disc Annular Repair Technology in Human Lumbar Spine written by Sarath C. Koruprolu and published by . This book was released on 2014 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of pre-operative data on the biomechanical stability of an annular repair device may influence the clinical management of lumbar spine surgery. Having the knowledge of the performance of various annular repair devices can assist in the selection of better choices for treatment. Numerous studies investigated the effect of various implants such as artificial nucleus replacement, repair or annular tears, novel annulus repair devices with full or partial discectomy etc. However, the area of nucleus and annulus repair technology still needs to be further researched upon to devise an alternative disc replacement device that would reduce pain, minimize the restriction of range of motion and decrease the degenerative effects on the adjacent segments. As a first step towards achieving this goal, an implant must be tested under appropriate biomechanical protocols to study its stability during complex physiological motion that is encountered clinically. This study determined the biomechanical performance of a novel annular repair device in an in-vitro in the human cadaveric lumbar spine. The test criterion was to evaluate implant migration during complex cyclic loading, study its effects on the range of motion of the functional spinal segment and intradiscal pressures. The overall stability of the device is studied under extreme physiological impact loading and the finite element analysis of the construct is conducted and compared to the in vitro data. Six human cadaveric lumbar functional spine unit specimens (L2-Sacrum

Download or read book Biomechanical Evaluation of Posterior Dynamic Stabilization Systems in Lumbar Spine written by Bharath K. Parepalli and published by . This book was released on 2009 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fusion has been the gold standard treatment for treating the disc degeneration. Fusion surgeries restrict the motion at the implanted level there by imposing additional load at the adjacent levels. Many clinical studies have showed that adjacent segment degeneration was observed in patients over time. In order to overcome problems with fusion devices, dynamic stabilization systems are being used to treat disc degeneration related problems. These implants restore intersegmental motion across the implanted level with minimal effects on the adjacent levels. In vitro cadaveric testing was conducted on seven harvested sheep spines using established protocols. Axient was implanted in the spines 3 months prior to sacrificing. Main aim of this testing is to see if the performance is altered by the presence of surrounding muscle tissue. The specimens were prepared and tested under load control protocol. All six loading modes were tested by applying a pure moment of 10Nm (in steps of 2.5Nm) and angular displacement was calculated for the following cases: 1) Intact spine + Axient with surrounding muscle tissue, 2) Intact spine + Axient with muscle tissue removed, 3) Intact spine (with implant removed). Relative motion of L4 vertebra with respect to L5 was calculated. Statistical analysis was performed (on the implanted level data) to see if there is a statistical significance between cases 1 and 2. Biomechanical testing was also performed on 4 human cadavers to observe the trend with Axient compared to FE results. A validated 3-D non linear finite element model of the L3-S1 lumbar spine was used to evaluate biomechanics of various dynamic stabilization systems in comparison with traditional rigid rod system. The model was modified at L4-L5 level to simulate three different dynamic stabilization systems (DSFM-1, DSFM-2 and Axient, Innovative Spinal Technologies Inc., Mansfield, MA). Grade I was simulated at L4-L5 level. Follower preload of 400N and a 10Nm bending moment was applied to simulate physiological flexion, extension, lateral bending and axial rotation. Range of motion (ROM), intra discal pressure (IDP) and facet loads were calculated for all the models. Implant with better performance was then compared with fusion system in both grade I and grade II degenerated spines. In vitro results showed that there is no significant difference in the performance of the Axient with and without surrounding muscle tissue in terms of range of motion. Coming to FE results, Axient performed better over the other two implants (DSFM-1 and DSFM-2). Axient device was able to restore the motion at the implanted level compared to fusion device. Higher motions were observed at the adjacent level (L5-S1) with fusion device compared to intact and injured models. Both devices were able to stabilize the diseased spine and unload the treated disc.

Download or read book Textbook of Surgical Management of Lumbar Disc Herniation written by PS Ramani and published by JP Medical Ltd. This book was released on 2013-12-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Low back pain and sciatica may often be attributed to herniation of the lumbar intervertebral disc. This book is a comprehensive guide to surgical procedures for the management of lumbar disc herniation. Divided into seven sections, the first few chapters discuss historical aspects and basics, and radiological investigations. The following section provides in depth coverage surgical techniques for different lumbar spine disorders. Each procedure is described step by step, with intraoperative photographs and diagrams helping to explain the methodology. The final sections examine complications and follow up. This invaluable manual is authored by internationally acclaimed spinal surgeons, and is commissioned by the World Federation of Neurological Societies (WFNS). Key points Comprehensive guide to surgical procedures for management of lumbar disc herniation Covers procedures for numerous associated disorders Authored by internationally acclaimed spinal surgeons Commissioned by WFNS

Download or read book Injury Analysis and Treatment Planning with Virtual Human Body Models written by Fuhao Mo and published by Frontiers Media SA. This book was released on 2024-07-25 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life-saving medical and scientific research-based interventions are extending people's lives and saving the lives of people who have suffered from diseases and injuries. This has led to an increased need for the development of technical and medical devices for the prevention, rehabilitation, and treatment of injuries. With the development of computer technology, more and more virtual models of the human body have been developed for biomedical and biomechanical research and application. Reliable virtual body models can efficiently improve injury prediction and rehabilitation, as well as disease diagnosis and treatment. For the past decade, biomechanical virtual human body models have experienced major advancements in terms of development methods, model biofidelity, availability, and applications.

Download or read book Intervertebral Disc Regeneration written by Benjamin Gantenbein and published by Mdpi AG. This book was released on 2022-01-11 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.

Download or read book The Intervertebral Disc written by Irving M. Shapiro and published by Springer Science & Business Media. This book was released on 2013-09-02 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scientists and clinicians, the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques. The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of graduate students, medical students, interns and fellows.

Download or read book The Lumbar Spine written by Harry N. Herkowitz and published by Lippincott Williams & Wilkins. This book was released on 2004 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt: The official publication of the International Society for the Study of the Lumbar Spine, this volume is the most authoritative and up-to-date reference on the lumbar spine. This edition provides more balance between basic science and clinical material and has been completely reorganized for easy reference. New chapters cover gene therapy, outcomes assessment, and alternatives to traditional nonoperative treatment. The editors have also added chapters on preparation for surgery, surgical approaches, spinal instrumentation, and bone grafts. Chapters on specific disorders have a consistent structure—definition, natural history, physical examination, imaging, nonoperative treatment, operative treatment, postoperative management, results of surgery, and complications.

Download or read book Comprehensive Biomaterials II written by Kevin Healy and published by Elsevier. This book was released on 2017-05-18 with total page 4865 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Download or read book An Experimental Method for Measuring written by and published by DIANE Publishing. This book was released on with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Biomechanics of Back Pain E Book written by Michael A. Adams and published by Elsevier Health Sciences. This book was released on 2012-11-19 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by experts of international renown, the new edition of The Biomechanics of Back Pain forms a bridge between the latest research and the effective clinical management of patients with back problems. Now published for the first time in full colour, the volume presents a unique synthesis of the latest research findings and explains its recent changes in emphasis - from trying to understand and reverse age-related spinal degeneration to addressing the soft tissue causes of pain. New chapters are devoted to Sensorimotor Control, and Cervical Spine Anatomy and Biomechanics, while a bonus website contains useful PowerPoint presentations, which include seminars entitled Back Pain and Forces on the Spine as well as an overview of the Psychosocial Flags Framework. Clinically orientated and highly practical throughout, The Biomechanics of Back Pain has become the standard platform by which readers keep abreast of research and developments in the field and is essential for all clinicians involved in the care and treatment of patients with back pain, as well as for those studying its causes and methods of prevention. - Established authoritative text for clinicians, lecturers, researchers and those working in the medico-legal arena - Emphasizes the latest perspectives in research and shows how it is now leading to advances in clinical methodology - Provides an overview of the best original research – including more than 350 new references – to provide researchers with the latest and most important information relating to back pain - Contains over 150 full-colour line artworks and more than 60 photographs - Additional chapters devoted to Sensorimotor Control, and Cervical Spine Anatomy and Biomechanics - Includes more than 350 new references - Now published in full colour with improved page design and navigation - Bonus website containing useful PowerPoint presentations, which include seminars entitled Back Pain and Forces on the Spine as well as an overview of the Psychosocial Flags Framework

Download or read book Cutting Edge Enabling Technologies for Regenerative Medicine written by Heung Jae Chun and published by Springer. This book was released on 2018-10-24 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the latest enabling technologies for regenerative medicine. The opening section examines advances in 3D bioprinting and the fabrication of electrospun and electrosprayed scaffolds. The potential applications of intelligent nanocomposites are then considered, covering, for example, graphene-based nanocomposites, intrinsically conductive polymer nanocomposites, and smart diagnostic contact lens systems. The third section is devoted to various drug delivery systems and strategies for regenerative medicine. Finally, a wide range of future enabling technologies are discussed. Examples include temperature-responsive cell culture surfaces, nanopatterned scaffolds for neural tissue engineering, and process system engineering methodologies for application in tissue development. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth novel biomaterials for regenerative medicine.

Download or read book The Aging Spine written by Max Aebi and published by Springer Science & Business Media. This book was released on 2005-02-23 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "Bone and Joint Decade" draws our attention with increased intensity to the problem of the changes related to aging of our musculoskeletal system and the associated socioeconomic implications. In view of the increasing age of the worldwide population the impact seems to be tremendous. The editors of The Aging Spine pick up this interesting topic and engage opinion leaders to contribute their knowledge in this supplement. The various contributions cover most of the important problems, which are included in the vast specter of aging spine: osteoporosis, spinal stenosis, and tumors of the spine. The aging spine will be an everpresent issue in the life of a physician taking care of the different pathologies of the spine. This text will help to better understand the nature of the different changes in the spine of the elderly. It contributes to enabling us to diagnose and to treat this complex problem in an appropriate way.

Download or read book Handbook of Spine Technology written by Boyle C. Cheng and published by Springer. This book was released on 2021-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the most authoritative and up-to-date reference on spine technology written for practitioners, researchers, and students in bioengineering and clinical medicine. It is the first resource to provide a road map of both the history of the field and its future by documenting the poor clinical outcomes and failed spinal implants that contributed to problematic patient outcomes, as well as the technologies that are currently leading the way towards positive clinical outcomes. The contributors are leading authorities in the fields of engineering and clinical medicine and represent academia, industry, and international government and regulatory agencies. The chapters are split into five sections, with the first addressing clinical issues such as anatomy, pathology, oncology, trauma, diagnosis, and imaging studies. The second section, on biomechanics, delves into fixation devices, the bone implant interface, total disc replacements, injury mechanics, and more. The last three sections, on technology, are divided into materials, commercialized products, and surgery. All appropriate chapters will be continually updated and available on the publisher’s website, in order to keep this important reference as up-to-date as possible in a fast-moving field.

Download or read book Surgery of the Spine and Spinal Cord written by Erik van de Kelft and published by Springer. This book was released on 2016-07-04 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers essential guidance on selecting the most appropriate surgical management option for a variety of spinal conditions, including idiopathic problems, and degenerative disease. While the first part of the book discusses the neuroanatomy and biomechanics of the spine, pain mechanisms, and imaging techniques, the second guides the reader through the diagnostic process and treatment selection for disorders of the different regions of the spine, based on the principles of evidence-based medicine. I.e., it clearly explains why a particular technique should be selected for a specific patient on the basis of the available evidence, which is carefully reviewed. The book identifies potential complications and highlights technical pearls, describing newer surgical techniques and illustrating them with the help of images and accompanying videos. Though primarily intended for neurosurgeons, the book will also be of interest to orthopaedic surgeons, specialists in physical medicine, and pain specialists. ​

Download or read book Case Studies in Pain Management written by Alan David Kaye and published by Cambridge University Press. This book was released on 2014-10-16 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by internationally recognized pain experts, this book offers 73 clinically relevant cases, accompanied by discussion in a question-and-answer format.

Download or read book Low Back Disorders written by Stuart McGill and published by Human Kinetics. This book was released on 2007 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of 'Low Back Disorders' provides research information on low back problems and shows readers how to interpret the data for clinical applications.

Download or read book Advances In Tissue Engineering written by Julia M Polak and published by World Scientific. This book was released on 2008-08-20 with total page 947 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field./a