Download or read book Biology of Cardiovascular and Metabolic Diseases written by Chaya Gopalan and published by Academic Press. This book was released on 2022-01-11 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases with health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure and way to treat underlying conditions. Focuses succinctly on the physiology and pathophysiology of cardiovascular and metabolic diseases Written in a concise and easy to read manner, allowing readers to quickly understand concepts Highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure
Download or read book Cardiovascular and Metabolic Disease written by Philip Peplow and published by Royal Society of Chemistry. This book was released on 2015-05-22 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular and metabolic diseases remain the number one cause of death in developed countries and their prevalence is increasing rapidly in developing nations. This book brings together the recent information on these disorders and the links that exist between them in order to provide a complete picture of drug discovery for these conditions. The main three sections comprehensively discuss obesity, hypertension and cardiovascular disease, and diabetes in turn, following an introduction to the molecular links between them. The final chapter provides perspectives on future directions of the field. Chapters are contributed by leaders in the field from academia and industry and cover biomarkers, risk factors, gene-environment interactions, therapies and the various types of animal models that have been used to study each disease. Case studies describing the implementation of animal models in drug development further enhance the book’s usefulness as a comprehensive guide to this important therapeutic area. Providing a full picture of the various types of animal models that have been used to study obesity, hypertension, and insulin resistance with recent case studies, this book provides a valuable resource for medicinal chemists and clinicians working in these disease areas.
Download or read book Prevention and Management of Cardiovascular and Metabolic Disease written by Peter Kokkinos and published by John Wiley & Sons. This book was released on 2023-04-24 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.
Download or read book Nutritional and Metabolic Bases of Cardiovascular Disease written by Mario Mancini and published by John Wiley & Sons. This book was released on 2011-07-11 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extraordinary advances in the understanding of the links between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of knowledge in the field. As a result, it is now imperative that clinicians who care for patients with CVD or its key risk factors have a solid understanding of the often complex interrelationships between cardiovascular health and chronic diseases such as diabetes and obesity. Written by a team of international thought leaders in cardiology, endocrinology, diabetology and nutritional science, this important new book: Examines and updates the role of obesity, hyperlipidemia, diabetes, hypertension, thrombosis, and aging in atherogenesis Describes in detail the scientific and clinical evidence of the etiopathogenesis of ischemic heart disease as well as of peripheral and cerebrovascular disease Focuses on the 6 topics that will be of greatest interest to readers: 1) general nutrition, 2) metabolic syndrome and diabetes, 3) hyperlipidemia and atherosclerosis, 4) hypertension and cerebrovascular disease, 5) hemostasis and thrombosis, 6) aging Throughout the book, in clear and accessible text, contributors illuminate the close relationship between dietary habits, the metabolic processes of nutrients, and their impact on the cardiovascular system, always with an eye on how the physician can use this information to implement better cardiovascular prevention and improve patient care. Nutritional and Metabolic Bases of Cardiovascular Disease is ideal for those who need to update their knowledge of the links between nutrition, metabolism and CVD, from trainees, clinicians and clinical investigators in cardiovascular medicine to endocrinologists, diabetologists, and nutritionists.
Download or read book Extracellular Vesicles in Cardiovascular and Metabolic Diseases written by Junjie Xiao and published by Springer Nature. This book was released on 2023-09-22 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
Download or read book Genome Editing in Cardiovascular and Metabolic Diseases written by and published by . This book was released on 2022-12-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Novel Concepts in Cardiac Energy Metabolism From Biology to Disease written by Thomas Pulinilkunnil and published by Frontiers Media SA. This book was released on 2019-08-08 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Cellular and Molecular Pathobiology of Cardiovascular Disease written by Monte Willis and published by Academic Press. This book was released on 2013-12-23 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology
Download or read book High and Rising Mortality Rates Among Working Age Adults written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-12-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiac Energy Metabolism in Health and Disease written by Gary D. Lopaschuk and published by Springer. This book was released on 2014-08-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.
Download or read book Metabolic Disorders and Shen in Integrative Cardiovascular Chinese Medicine written by Anika Niambi Al-Shura and published by Academic Press. This book was released on 2020-07-30 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Disorders and Shen in Integrative Cardiovascular Medicine, volume seven in the Integrative Cardiovascular Chinese Medicine series, presents the connection between metabolic diseases that affect the cardiovascular system and mental health through both Chinese and Western medicine explanations. Sections discuss the etiology of metabolic disorders of blood sugar disorders, lipid disorders, inflammatory disorders and shen, the clinical significance and differentiations in both Western and Chinese medicine, and prescriptions and the medicated diet, including main acupoints, remedies and medicines used in Western and Chinese medicine and the combination of medicinal herbs and food for Chinese diet therapy. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base that not only guides clinical practice, but also encourages collaboration between Chinese and Western medicine practitioners. Gives basic medical science and TCM theory background on lipids, blood sugar, inflammation and shen with clinical significance and diagnosis Provides treatment methods and advice, including nutritional therapy and the Chinese medicine dietary plan Prepares readers for advanced study within Integrative Cardiovascular Chinese Medicine
Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.
Download or read book Oxidative Stress in Cardiovascular Metabolic Diseases written by Ali Hussein Eid and published by Springer. This book was released on 2024-08-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book dissects the role of oxidative stress in the pathogenesis of the leading causes of global morbidity and mortality, i.e.cardiovascular and metabolic diseases. The chapters discuss topics related to the role reactive oxygen species (ROS) play in hypertension, atherosclerosis,diabetes, obesity and related pathologies. The authors also shed light on gender differences in the onset and pathologies of some of these diseases. Moreover, how ROS and aging interplay to precipitate cardiovasculo-metabolic disease is discussed and highlighted. Preventive measures that can abrogate ROS-induced cardiovasclo-metabolic disease are discussed and clarified in the hope of reducing such a debilitating battery of diseases. A section dedicated to antioxidants as potential therapy is also included. Furthermore, given the complexity of the mechanisms implicated in ROS-modulated responses, it remains challenging to assert a conclusive argument and pre-determined regimen for incorporating antioxidants into conventional therapies. Nonetheless, results from some clinical trials appear promising, warranting the addition of a chapter dedicated to such human trials. In all of the chapters, the molecular, cellular, genetic, and pharmacological mechanisms implicated are covered from an applied science perspective. This is an ideal book for basic researchers in the biomedical field, graduate students in biological and biomedical fields, medical students, instructors in medical and graduate schools, and professionals working for pharmaceutical companies.
Download or read book New Lipid Lowering Therapies for Cardiovascular and Metabolic Diseases Lessons from the Past and Future Challenges written by Ahmed Bakillah and published by MDPI. This book was released on 2019-10-16 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates some of the most recent research efforts that have been made in lowering plasma cholesterol levels in patients with CVD. Selected articles aimed to illuminate advances and urgent challenges in the management of CVD, including disease management using statin-combined therapeutic strategies.
Download or read book Aging and Health written by Anatoli I. Yashin and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.
Download or read book Cardiac Metabolism in Health and Disease written by Salah Abdel-aleem and published by Springer. This book was released on 2012-10-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.
Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
