Download or read book Experimental Design for Biologists written by David J. Glass and published by CSHL Press. This book was released on 2007 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.
Download or read book The Rise of Experimental Biology written by Peter L. Lutz and published by Springer Science & Business Media. This book was released on 2002-04-19 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peter Lutz, PhD, brilliantly traverses the major milestones along the evolutionary path of biomedicine from earliest recorded times to the dawn of the 20th century. With an engaging narrative that will have you turning "just one more page" well into the night, this book revealingly demonstrates just how the modern scientific method has been shaped by the past. Along the way the reader is treated to some delightfully obscure anecdotes and a treasure trove of rich illustrations that chronicle the tortuous history of biomedical developments, ranging from the bizarre and amusing to the downright macabre. The reader will also be introduced to the major ideas shaping contemporary physiology and the social context of its development, and also gain an understanding of how advances in biological science have occasionally been improperly used to satisfy momentary social or political needs.
Download or read book Landmark Experiments in Molecular Biology written by Michael Fry and published by Academic Press. This book was released on 2016-06-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Download or read book Experimental Techniques in Bacterial Genetics written by Stanley R. Maloy and published by Jones & Bartlett Learning. This book was released on 1990 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction To Experimental Design And Statistics For Biology written by David Heath and published by CRC Press. This book was released on 1995-10-26 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This illustrated textbook for biologists provides a refreshingly clear and authoritative introduction to the key ideas of sampling, experimental design, and statistical analysis. The author presents statistical concepts through common sense, non-mathematical explanations and diagrams. These are followed by the relevant formulae and illustrated by w
Download or read book Developmental Biology written by Mary S. Tyler and published by Sinauer Associates, Incorporated. This book was released on 1994 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Experimental Design and Data Analysis for Biologists written by Gerry P. Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential textbook for any student or researcher in biology needing to design experiments, sample programs or analyse the resulting data. The text begins with a revision of estimation and hypothesis testing methods, covering both classical and Bayesian philosophies, before advancing to the analysis of linear and generalized linear models. Topics covered include linear and logistic regression, simple and complex ANOVA models (for factorial, nested, block, split-plot and repeated measures and covariance designs), and log-linear models. Multivariate techniques, including classification and ordination, are then introduced. Special emphasis is placed on checking assumptions, exploratory data analysis and presentation of results. The main analyses are illustrated with many examples from published papers and there is an extensive reference list to both the statistical and biological literature. The book is supported by a website that provides all data sets, questions for each chapter and links to software.
Download or read book An Introduction to the Study of Experimental Medicine written by Claude Bernard and published by . This book was released on 1927 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: First English translation of the classical work on the principles of physiological investigation in life sciences.
Download or read book Leaving Certificate Biology Experiment Book written by Joe Rice (MSc.) and published by . This book was released on 2009 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Experimental Design for Laboratory Biologists written by Stanley E. Lazic and published by Cambridge University Press. This book was released on 2016-12-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.
Download or read book Experimental Evolution written by Theodore Garland and published by Univ of California Press. This book was released on 2009-12-03 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field's range of research.
Download or read book Experimental Developmental Biology written by Laura R. Keller and published by Academic Press. This book was released on 1999 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is designed for use as a lab manual in college-level courses in developmental biology or animal development. In each exercise, students examine gametes and developing embryos of a single species, and also perform several experiments to probe its developmental process.
Download or read book Experimental Approaches to Conservation Biology written by Malcolm Gordon and published by Univ of California Press. This book was released on 2004-09-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are living in the early stages of a looming worldwide extinction crisis. Abundant evidence shows that the current rate of species extinctions is nearing its highest level since the asteroid collision 65 million years ago, and that humans are largely responsible. This book addresses the urgent need to understand and find solutions to this crisis. Written by an international team of contributors who are among the best-known and most active experimental biologists working in the field of conservation biology today, it provides a unique approach by focusing on individual species rather than whole plant and animal communities. Emphasizing throughout how conservation biology can benefit from an experimental approach, the book looks at a wide range of terrestrial and aquatic species—from giant pandas and tree snails to sea turtles and Steller sea lions—and demonstrates what can be done both to preserve rare species and to combat invasive organisms. Finally, contributors show how we can bridge the gap between policy makers and research scientists in order to develop lasting solutions to these problems.
Download or read book Fungi written by Ramesh Maheshwari and published by CRC Press. This book was released on 2016-04-19 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fungi are now at the forefront of research on mechanisms in gene silencing, biological rhythm, mating processes, biogenesis of intracellular organelles, adaptations to hostile habitats, structure of natural populations, and speciation. Because of their small genomes, fungi are being used in "systems biology" to understand the connections between ge
Download or read book Water in Biology Chemistry and Physics written by G. Wilse Robinson and published by World Scientific. This book was released on 1996 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: The central theme, which threads through the entire book, concerns computational modeling methods for water. Modeling results for pure liquid water, water near ions, water at interfaces, water in biological microsystems, and water under other types of perturbations such as laser fields are described. Connections are made throughout the book with statistical mechanical theoretical methods on the one hand and with experimental data on the other. The book is expected to be useful not only for theorists and computer analysts interested in the physical, chemical, biological and geophysical aspects of water, but also for experimentalists in these fields.
Download or read book Comparative Toxicogenomics written by and published by Elsevier. This book was released on 2008-07-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional genomics has come of age. No longer is it an adventure for the avant garde scientist, but it has become an increasingly standardized mainstream tool accessible to any modern biological laboratory. Toxicogenomics studies are now generating an avalanche of data that, with the aid of established informatics methodology, is being translated into biologically meaningful information. This is enabling us to start harvesting the benefits from years of investment in terms of technology, time, and (of course) money. It is therefore timely to bring together leading toxicologists with a wide variety of scientific aims in this book to demonstrate how microarray technology can be successfully applied to different research areas. This book transects biology from bacteria to human, from ecologically relevant sentinel organisms to well-characterized model species, and represents the full toxicogenomics arena from exploratory "blue sky" science to the prospects for incorporation into regulatory frameworks. Reviews some of the first really fruitful studies made in this area Covers different organisms ranging from humans to model species and environmental sentinels Provides a broad view of the area, increasing its attractiveness to researchers working in a variety of specialties
Download or read book The Emotional Cerebellum written by Michael Adamaszek and published by Springer Nature. This book was released on 2022-07-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emotions represent a critical aspect of daily life in humans. Our understanding of the mechanisms of regulation of emotions has increased exponentially these last two decades. This book evaluates the contribution of the cerebellum to emotion. It outlines the current clinical, imaging and neurophysiological findings on the role of the cerebellum in key aspects of emotional processing and its influence on motor and cognitive function and social behavior. In the first section, the reader is introduced to the contributions of the cerebellum to various emotion domains, from emotion perception and recognition to transmission and encoding. Subsequent chapters provide a comprehensive picture of the neurophysiology and topography of emotion in the cerebellum and illustrate the convergence of theoretical and empirical research. Additional chapters address the cerebellum's involvement in emotional learning, emotional pain, emotional aspects of body language and perception, and its relations to social cognition including morality, music, and art. Finally, neuropsychiatric aspects of the cerebellum's influence on mood disorders and the current state of therapeutic options, including noninvasive stimulation approaches, complete the overview. This is the first book summarizing the current state of knowledge on the contribution of the cerebellum to important aspects of emotion. It is an essential reference for students, trainees, neuroscientists, researchers, and clinicians in neuroscience, neurology, neurosurgery and psychology involved in the study of emotions. The authors are renowned scientists in the field of cerebellar research.
