Download or read book Biologie und Epidemiologie der Hormonersatztherapie Biology and Epidemiology of Hormone Replacement Therapy written by M. A. Lewis and published by Springer. This book was released on 2014-11-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.

Download or read book Biologie und Epidemiologie der Hormonersatztherapie Biology and Epidemiology of Hormone Replacement Therapy written by M. A. Lewis and published by Springer Science & Business Media. This book was released on 2007-05-24 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.

Download or read book PET Chemistry written by P.A. Schubiger and published by Springer Science & Business Media. This book was released on 2007-01-19 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.

Download or read book Appropriate Dose Selection How to Optimize Clinical Drug Development written by J. Venitz and published by Springer Science & Business Media. This book was released on 2007-03-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimal dose individualization has become more important in improving clinical efficacy and safety. This is due in part to the variability in drug response. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. This book reviews innovative methods, tools and examples of rational drug development strategies, particularly for novel oncological agents.

Download or read book Fertility Preservation in Oncological and Non Oncological Diseases written by Michael von Wolff and published by Springer Nature. This book was released on 2020-06-30 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical book focuses on the most recent advances in fertility preservation in oncological and non-oncological patients. It presents the steps that need to be followed prior to treatment for successful fertility preservation, and describes in detail the medical conditions requiring fertility preservation, including precise information on the risk of fertility loss, prognosis, risk of ovarian metastasis and other possible risks. The book also provides information on how to perform the preservation techniques (success rates, risks, etc.) and on what to do after the treatment (in cases of bleeding during chemotherapy, menopause, wish to conceive, etc.). Written by experts in the field, including members of the globally known network FertiPROTEKT and leading oncologists and specialists, this practical and easy-to-use book is a valuable resource for all clinicians involved in fertility preservation for patients with specific diseases

Download or read book Sentinel Lymph Node Biopsy written by Hiram S. Cody and published by CRC Press. This book was released on 2001-11-08 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.

Download or read book Building an Import Export Business written by Kenneth D. Weiss and published by John Wiley & Sons. This book was released on 2011-04-18 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bestselling, up-to-date guide shows you how to start your own import/export business, from researching a raw idea to a successful launch to ongoing, profitable business operations. Complete with real-life examples from importers and exporters, it helps you every step of the way, from targeting a market and preparing a business plan to dealing with foreign currencies, shipping procedures, customs requirements, and more. It also shares tips to help you take advantage of NAFTA and other trade pacts, plus online resources to help you start and grow your business.

Download or read book Ovarialtumoren written by G. Dallenbach-Hellweg and published by Springer. This book was released on 1982-05-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die Ovarialtumoren gehoren heute mit zu den haufigsten Tumoren des weiblichen Genitale. Ihre morphologische Differentialdiagnostik und die sich darauf aufbauende gezielte Therapie ist aufgrund der Vielfalt dieser Tumoren ungleich viel komplizierter als in anderen Organen. Dement­ sprechend liegt der Schwerpunkt dieses Buches auf dem Gebiet der Histo­ pathologie. Spezialkenntnisse insbesondere tiber die selteneren Formen der Ovarialtumoren hangen von groBen Fallzahlen abo Hier ist der inter­ nationale Erfahrungsaustausch von vorrangiger Bedeutung. Die derzeit weltweit anerkannte histogenetische Klassifikation der WHO erfahrt an­ hand der Erfahrungen an drei deutschen Frauenkliniken kleine Erganzun­ gen und Variationen. Einige Lander, Z. B. Israel verfUgen tiber groBe epi­ demiologische Untersuchungen, deren Ergebnisse korrelierend aufgenom­ men sind. Zur klinischen Diagnostik wurden in den letzten lahren mo­ dernste Untersuchungsmt;thoden neu eingefUhrt; ihre Anwendung setzt jedoch individuell anzupassende kritische Indikationsstellungen voraus. AbschlieBend werden die sich sehr differenziert auf der histologischen Diagnostik aufbauenden modernen Moglichkeiten einer gezielten Thera­ pie der Ovarialtumoren ausfUhrlich diskutiert. Hier steht die Chemothera­ pie im Vordergrund. 1m Hinblick auf die Frage einer Hormonbehandlung kommt neuerdings auch dem Rezeptornachweis im Tumorgewebe Bedeu­ tung zu. Diese Zusammenstellung spricht somit gleichermaBen Pathologen, Onkologen und Gynakologen an und will versuchen, gegenseitige Infor­ mationslticken der Fachexperten auf dem Gesamtgebiet der Problematik der Ovarialtumoren in zumutbarer Klirze zu schlieJ3en. Daher nehmen ge­ rade die selteneren und bisher weniger bekannten Tumoren in Bild und Text einen verhaltnismaBig breiten Raum ein auf Kosten der hinlanglich bekannten haufigeren Formen, bei denen Spezia1fragen der Differenti- diagnostik aufgrund neuester Erkenntnisse im Vordergrund stehen.

Download or read book Expected and Unexpected Consequences of the Educational Expansion in Europe and the US written by Andreas Hadjar and published by Haupt Verlag AG. This book was released on 2009 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Molecular Oncology of Breast Cancer written by Jeffrey Stuart Ross and published by Jones & Bartlett Learning. This book was released on 2005 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive reference to focus on the molecular development and treatment of the disease, Molecular Oncology of Breast Cancer provides authoritative information across the spectrum of modern breast cancer research and clinical care. Edited by two world-class experts in cancer pathology, drug development, and patient management, with contributions from over 50 experts, this ground-breaking text describes the genes, proteins, and biologic pathways that are being evaluated today and will be tested in the future to derive the molecular signature of each newly diagnosed breast cancer. For the first time, readers can now obtain, in a single volume, up-to-date information on how molecular-based tests are being used to identify predisposition, provide earliest detection, decide classification based on genetic fingerprint and predict therapy-specific outcomes. MOBC includes unique chapters on functional imaging and the impact of targeted therapies on the FDA approval process. This book gives readers vital, up-to-date information on important molecular discoveries that affect the everyday management of the breast cancer patient.

Download or read book Abductive Reasoning written by Atocha Aliseda and published by Springer Science & Business Media. This book was released on 2006-02-16 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abductive Reasoning: Logical Investigations into Discovery and Explanation is a much awaited original contribution to the study of abductive reasoning, providing logical foundations and a rich sample of pertinent applications. Divided into three parts on the conceptual framework, the logical foundations, and the applications, this monograph takes the reader for a comprehensive and erudite tour through the taxonomy of abductive reasoning, via the logical workings of abductive inference ending with applications pertinent to scientific explanation, empirical progress, pragmatism and belief revision.

Download or read book Backstabbing for Beginners written by Michael Soussan and published by Bold Type Books. This book was released on 2010-06-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: A riveting, first-person account of the backstabbing and hypocrisy that led to the U.N.'s Oil-for-Food Program becoming the most corrupt enterprise ever overseen by the international community.

Download or read book The Politics of Hunger in India written by B. Currie and published by Springer. This book was released on 2000-03-29 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do people starve in democratic polities? It is often claimed that as government must respond to public needs in times of crisis, democracy has reduced famine in India since Independence. This book seeks to identify the processes which generate and perpetuate hunger in India, and what sort of intervention by public and private agencies are best suited to combat this problem. Drawing on fieldwork in the much publicised Kalahandi district, Bob Currie explains why problems of poverty and alleged starvation remain despite regular elections and extensive regional and national publicity.

Download or read book Volume 9 Aesthetics and Philosophy of Art written by Guttorm Fløistad and published by Springer Science & Business Media. This book was released on 2007-03-16 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book continues the series Contemporary Philosophy (International Institute of Philosophy), which surveys significant trends in contemporary philosophy. The new volume on Aesthetics, comprising nineteen surveys, shows the variety of approaches to Aesthetics in various cultures. The close connection between aesthetics and religion and between aesthetics and ethics is emphasized in several contributions.

Download or read book Advances in Web Intelligence written by Piotr S. Szczepaniak and published by Springer. This book was released on 2005-05-24 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years the Internet has become a source of data and information of indisputable importance and has immensely gained in acceptance and popularity. The World Wide Web (WWW or Web, for short), frequently named “the nervous system of the infor- tion society,” offers numerous valuable services leaving no doubt about the signi?cance of the Web in our daily activities at work and at home. Consequently, we have a clear aspiration to meet the obvious need for effective use of its potential by making - provements in both the methods and the technology applied. Among the new research directions observable in Web-related applications, intelligent methods from within the broadly perceived topic of soft computing occupy an important place. AWIC, the “Atlantic Web Intelligence Conferences” are intended to be a forum for exchange of new ideas and novel practical solutions in this new and exciting ?eld. The conference was born as an initiative of the WIC-Poland and the WIC-Spain Research Centres, both belonging to the Web Intelligence Consortium – WIC (http://wi-consortium.org/). So far, three AWIC conferences have been held: in Madrid, Spain (2003), in Cancun, Mexico (2004), and in ?ódz, ́ Poland (2005).

Download or read book Acoustic MIMO Signal Processing written by Yiteng Huang and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Telecommunication systems and human-machine interfaces have begun using multiple microphones and loudspeakers to render interaction more lifelike, and more efficient. This raises acoustic signal processing problems under multiple-input multiple-output (MIMO) scenarios, encompassing distant speech acquisition, sound source localization and tracking, echo and noise control, source separation and speech dereverberation, and many others. The book opens with an acoustic MIMO paradigm, establishing fundamentals, and linking acoustic MIMO signal processing with classical signal processing and communication theories. The second part of the book presents a novel analysis of acoustic applications carried out in the paradigm to reinforce the fundamentals of acoustic MIMO signal processing.

Download or read book Action and Responsibility written by Andrew Sneddon and published by Springer Science & Business Media. This book was released on 2006-01-27 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an exploration of what it takes for an event to count as an action. I first became interested in this topic nearly a decade ago while working on a different topic. I kept coming across philosophers making claims about the nature of action that seemed false or at least dubious to me. As a consequence I turned to the philosophy of action directly, to get to the heart of the matter. I have wrestled with this territory ever since. I hope that, with this book, I have finally earned the intuitions that put me at odds with the philosophers I was originally reading. This book develops ideas in Part Two of my doctoral dissertation, which I wrote at Queen’s University in Kingston, Ontario, Canada. I loved being at Queen’s, for both professional and personal reasons. My thanks go to the Social Sciences and Humanities Research Council of Canada for financial support as a doctoral candidate. Steve Leighton and Ronald de Sousa were readers for my dissertation. They provided some early and invaluable challenges to the ideas developed here. My deepest debt of gratitude is owed to David Bakhurst, my supervisor. I learned a lot from David; this book would not be the same without his help.