Download or read book Affinity Chromatography and Biological Recognition written by Irwin Chaiken and published by Elsevier. This book was released on 2012-12-02 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affinity Chromatography and Biological Recognition contains manuscripts presented at the Fifth International Symposium on Affinity Chromatography and Biological Recognition convened in June 12-17, 1983, at St. John's College in Annapolis, Maryland. Organized into six parts encompassing 82 chapters, the book begins by examining the growing synergism between affinity methods and the understanding and study of basic principles of biological recognition. The book then focuses on the trends and progress in the design and application of affinity methods for isolation, therapeutics, diagnostics, and biotechnology. Significant chapters are devoted to the contributions of affinity methodology in such areas as cell membrane receptors, quantitative properties of macromolecular interactions, microscale analytical and preparative applications of high performance affinity chromatography, antibodies as in vivo and in vitro diagnostic and therapeutic agents, and drug targeting. This volume will be a stimulus for broad and creative application of affinity concepts and methods in many fields of biomedical research and biotechnology.
Download or read book Specific Interaction and Biological Recognition Processes written by Zeno Simon and published by CRC Press. This book was released on 1993-06-16 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specific Interaction and Biological Recognition Processes is devoted to two major aspects of biological processes: specificity in biological recognition and the recognition processes themselves. Topics covered in specificity include the theoretical basis for specificity in biological recognition; the thermodynamic and chemical equilibrium background; and consideration of the relationship between size of combining sites and specificity. The use of semi-emperical potentials for calculating interaction energies and the potential of quantum chemistry methods for calculating receptor-effector affinities are also discussed. The various recognition processes described include DNA replication, transcription, translation, enzymatic reactions, transmembrane transport processes, mechanisms of action of hormones and other chemical messengers, and self-nonself recognition in immunology. Specific Interaction and Biological Recognition Processes will be a useful reference for molecular biologists, biochemists, enzymologists, immunologists oncologists, pharmaceutical researchers, and others interested in the topic.
Download or read book Biological Recognition and Assembly written by ICN-UCLA Symposium on Biological Recognition and Assembly$ (1979 : Keystone, Colorado) and published by . This book was released on 1980 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical and Biological Terrorism written by Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents and published by National Academies Press. This book was released on 1999-02-26 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Download or read book Biometric Systems written by James L. Wayman and published by Springer Science & Business Media. This book was released on 2005-09-20 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biometric Systems provides practitioners with an overview of the principles and methods needed to build reliable biometric systems. It covers three main topics: key biometric technologies, design and management issues, and the performance evaluation of biometric systems for personal verification/identification. The four most widely used technologies are focused on - speech, fingerprint, iris and face recognition. Key features include: in-depth coverage of the technical and practical obstacles which are often neglected by application developers and system integrators and which result in shortfalls between expected and actual performance; and protocols and benchmarks which will allow developers to compare performance and track system improvements.
Download or read book Biological Identification written by R. Paul Schaudies and published by Elsevier. This book was released on 2014-05-08 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Identification provides a detailed review of, and potential future developments in, the technologies available to counter the threats to life and health posed by natural pathogens, toxins, and bioterrorism agents. Biological identification systems must be fast, accurate, reliable, and easy to use. It is also important to employ the most suitable technology in dealing with any particular threat. This book covers the fundamentals of these vital systems and lays out possible advances in the technology. Part one covers the essentials of DNA and RNA sequencing for the identification of pathogens, including next generation sequencing (NGS), polymerase chain reaction (PCR) methods, isothermal amplification, and bead array technologies. Part two addresses a variety of approaches to making identification systems portable, tackling the special requirements of smaller, mobile systems in fluid movement, power usage, and sample preparation. Part three focuses on a range of optical methods and their advantages. Finally, part four describes a unique approach to sample preparation and a promising approach to identification using mass spectroscopy. Biological Identification is a useful resource for academics and engineers involved in the microelectronics and sensors industry, and for companies, medical organizations and military bodies looking for biodetection solutions. Covers DNA sequencing of pathogens, lab-on-chip, and portable systems for biodetection and analysis Provides an in-depth description of optical systems and explores sample preparation and mass spectrometry-based biological analysis
Download or read book Recognition Receptors in Biosensors written by Mohammed Zourob and published by Springer Science & Business Media. This book was released on 2010-01-08 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition receptors play a key role in the successful implementation of chemical and biosensors. Molecular recognition refers to non-covalent speci?c binding between molecules, one of which is typically a macromolecule or a molecular assembly, and the other is the target molecule (ligand or analyte). Biomolecular recognition is typically driven by many weak interactions such as hydrogen bo- ing, metal coordination, hydrophobic forces, van der Waals forces, pi-pi interactions and electrostatic interaction (due to permanent charges, dipoles, and quadrupoles) the polarization of charge distributions by the interaction partner leading to ind- tion and dispersion forces, and Pauli-exclusion-principle-derived inter-atomic repulsion, and a strong, “attractive” force arising largely from the entropy of the solvent and termed the hydrophobic effect. In recent years, there has been much progress in understanding the forces that drive the formation of such complexes, and how these forces are relate to the physical properties of the interacting molecules and their environment allows rational design of molecules and materials that interact in speci?c and desired ways. This book presents a signi?cant and up-to-date review of the various recognition elements, their immobilization, characterization techniques by a panel of dist- guished scientists. This work is a comprehensive approach to the recognition receptors area presenting a thorough knowledge of the subject and an effective integration of these receptors on sensor surfaces in order to appropriately convey the state-of the-art fundamentals and applications of the most innovative approaches.
Download or read book Chemical Recognition in Biology written by F. Chapeville and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of chemical recognition in biology were initiated about half a century ago with the flrst kinetic data obtained on enzyme catalysis and inhibition. They led to a rather static representation of the recognition process illustrated by the lock and key model that still continues to influence our overall image of recognition and its specificity. In several cases, crystallographic studies of enzyme-substrate complexes have supported this model. Indeed, in a crystallized ligand-enzyme complex, a close fltting is observed between the active center of the enzyme and the functional groups of the ligand. How ever, this does not necessarily result from a direct recognition process between rigid structures, but may result from a progressive adaptation during which the initial struc tures of the enzyme and the ligand are modified (induced-flt mechanism). Recently, a great deal of work has been devoted to the study of recognition in more complex systems such as the replication or the translation machin~ries; clearly, the extraordinary precision of such systems cannot be explained solely in terms of physical matching between enzymes and their substrates. This has led to a noticeable change of perspective in these areas. As a result of the new kinetic viewpoint, one rather focuses on the time-course of the processes, on the kinetic balance between steps of the reaction, on the energy-accuracy relationships and on the strategies which permit the achievement of high precision using relatively error-prone components in an appropriate dynamic interplay.
Download or read book Cellular and Biomolecular Recognition written by Raz Jelinek and published by John Wiley & Sons. This book was released on 2009-07-10 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Download or read book Emotion and Attention Recognition Based on Biological Signals and Images written by Seyyed Abed Hosseini and published by BoD – Books on Demand. This book was released on 2017-02-08 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emotion, stress, and attention recognition are the most important aspects in neuropsychology, cognitive science, neuroscience, and engineering. Biological signals and images processing such as galvanic skin response (GSR), electrocardiography (ECG), heart rate variability (HRV), electromyography (EMG), electroencephalography (EEG), event-related potentials (ERP), eye tracking, functional near-infrared spectroscopy (fNIRS), and functional magnetic resonance imaging (fMRI) have a great help in understanding the mentioned cognitive processes. Emotion, stress, and attention recognition systems based on different soft computing approaches have many engineering and medical applications. The book Emotion and Attention Recognition Based on Biological Signals and Images attempts to introduce the different soft computing approaches and technologies for recognition of emotion, stress, and attention, from a historical development, focusing particularly on the recent development of the field and its specialization within neuropsychology, cognitive science, neuroscience, and engineering. The basic idea is to present a common framework for the neuroscientists from diverse backgrounds in the cognitive neuroscience to illustrate their theoretical and applied research findings in emotion, stress, and attention.
Download or read book Strategies for Effective Improvements to the BioWatch System written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-05-17 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: BioWatch is the Department of Homeland Security's (DHS's) system for detecting an aerosolized biological attack using collectors that are positioned strategically across the country to continuously monitor the air for biological threats. As currently deployed, BioWatch collectors draw air through filters that field technicians collect daily and transport to laboratories, where professional technicians analyze the material collected on the filter for evidence of biological threats. As part of the BioWatch program's efforts to enhance its effectiveness and capabilities, particularly with regard to detecting biological threats in challenging indoor environments, DHS requested the National Academies of Sciences, Engineering, and Medicine hold a workshop to explore alternative and effective biodetection systems for aerosolized biological agents that would meet BioWatch's technical and operational requirements, integrate into the existing system architecture and public health infrastructure, and be deployable by 2027. This publication summarizes the presentations and discussions from the workshop.
Download or read book Basics of Molecular Recognition written by Dipankar Chatterji and published by CRC Press. This book was released on 2016-04-05 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basics of Molecular Recognition explores fundamental recognition principles between monomers or macromolecules that lead to diverse biological functions. Based on the author's longtime courses, the book helps readers understand the structural aspects of macromolecular recognition and stimulates further research on whether molecules similar to DNA o
Download or read book Recognition of Carbohydrates in Biological Systems Part A General Procedures written by Y. C. Lee and published by Elsevier. This book was released on 2003-09-15 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume, Recognition of Carbohydrates in Biological Systems, Part A: General Procedures, and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area. Covers the isolation/synthesis of substances used in studying interactions involving carbohydrates Discussed the methodology for measuring such interactions Biological roles for such interactions are also covered
Download or read book Carbohydrate Recognition written by Binghe Wang and published by John Wiley & Sons. This book was released on 2011-09-09 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Download or read book Handbook of Chemical and Biological Sensors written by R.F Taylor and published by CRC Press. This book was released on 1996-01-01 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Chemical and Biological Sensors focuses on the development of sensors to recognize substances rather than physical quantities. This fully inclusive book examines devices that use a biological sensing element to detect and measure chemical and biological species as well as those that use a synthetic element to achieve a similar result. A first port of call for anyone with a specific interest, question, or problem relating to this area, this comprehensive source of reference serves as a guide for practicing scientists and as a text for many graduate courses. It presents relevant physics to chemists, chemistry to materials scientists, materials science to electronic engineers, and fabrication technology to all of the above. In addition, the handbook is useful both to newcomers and to experienced researchers who wish to broaden their knowledge of the constituent disciplines of this wide-ranging field.
