Download or read book Biological Mechanisms of Radiation Actions at Low Doses written by United Nations. Scientific Committee on the Effects of Atomic Radiation and published by . This book was released on 2012 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: At its fifty-ninth session (21-25 May 2012), the Scientific Committee considered a short review document on the biological mechanisms of radiation actions at low doses. That document, unlike the Committee's standard full evaluations, was not intended to be comprehensive; it was rather intended to highlight major advances in the field that would provide guidance for developing the Committee's future programme of work. The document concludes that understanding of the mechanisms of so-called non-targeted delayed effects is improving and that there is some evidence for differential responses in gene and protein expression for high- and low-dose radiation exposures, but there is a lack of consistency and coherence among reports. There is as yet no indication of a causal association of those phenomena with radiation-related disease. With regard to immune response and inflammatory reactions, there is a clearer association with disease, but there is no consensus on the impact of radiation exposure, particularly at low doses, on those physiological processes. While the document focuses on mechanisms relevant to carcinogenesis, some of the processes considered may be relevant for tissue reactions, and improved understanding may therefore be helpful for assessing the potential risk of non-cancer diseases at low and protracted exposures.

Download or read book Biological Action of Low Doses of Radiation written by L. Kh Eidus and published by Nova Publishers. This book was released on 2001 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Action of Low Doses of Radiation - A Novel View on the Problem

Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.

Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Download or read book The Effects of Low Dose Radiation written by Elena Burlakova and published by CRC Press. This book was released on 2004-08-31 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this book show the results of investigations performed by Russian scientists in the field of low dose irradiation action. It is confirmed that low doses do have effects on the human organism and the environment and that the most serious consequences are observed in the far post-irradiation period. This branch of radiobiology, which developed after the Chernobyl accident and studied its consequences, is discussed in detail. The main part of reviews and articles is devoted to the aspects of low dose effects on the human and animal genome and far post-irradiation consequences. New details of mechanisms of low dose action are shown and methods of their determination are discussed. Furthermore, the adaptive response of organisms and the low dose effects on the immune system are demonstrated. Also, the difference between protection mechanisms against low dose irradiation and against high dose irradiation is shown and proved.

Download or read book Relative Radiation Sensitivities of Human Organ Systems written by John Lett and published by . This book was released on 1990 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 14: Relative Radiation Sensitivities of Human Organ Systems, Part II focuses on radiation sensitivities of particular human organ systems. The sensitivities are then assessed based on the severity and the rapidity in which the effects of radiation manifest. The opening chapter surveys the clinical and experimental data on approaches toward the prevention of bladder complications in clinical radiotherapy. A discussion on HeLa cells, which are of special importance in human cervical cancer therapy, is then presented. In presenting this topic, this book emph ...

Download or read book Sources Effects and Risks of Ionizing Radiation United Nations Scientific Committee on the Effects of Atomic Radiation UNSCEAR 2020 2021 Report written by United Nations Publications and published by UN. This book was released on 2022-06-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) established by the General Assembly in 1955 assesses the levels and effects of exposure to ionizing radiation on human health and the environment. This is the third of four volumes of scientific annexes provide the supporting scientific deliberations for the UNSCEAR 2020/2021 report to the General Assembly. Annex C "Biological mechanisms relevant for the inference of cancer risks from low dose and low-dose rate radiation" synthesizes the current knowledge on biological mechanisms of radiation actions at low doses and low-dose-rates, and assesses the implications for understanding the processes of cancer development after exposure to ionizing radiation, and for dose-response relationships of radiation-induced cancers.

Download or read book Low Dose Radiation written by Antone L. Brooks and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction -- Life and times of a radiation biologist -- A brief history of radiation biology -- The birth of the DOE Low Dose Radiation Research Program -- Early observations and new technology -- Paradigm shifts in low dose radiation biology and application of data -- Biomarkers of radiation exposure and dose -- Mechanisms of action -- Modeling -- Taking a systems biology approach to risk -- Program communication and monitoring -- Current and potential impact on standards -- Applying lessons learned to future direction -- Epilogue.

Download or read book Radiation Biophysics ionizing Radiations written by I︠U︡riĭ Borisovich Kudri︠a︡shov and published by Nova Publishers. This book was released on 2008 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Download or read book Sources Effects and Risks of Ionizing Radiation United Nations Scientific Committee on the Effects of Atomic Radiation UNSCEAR 2020 2021 Report Volume III written by United Nations Scientific Committee on the Effects of Atomic Radiation and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) established by the General Assembly in 1955 assesses the levels and effects of exposure to ionizing radiation on human health and the environment. This is the third of four volumes of scientific annexes provide the supporting scientific deliberations for the UNSCEAR 2020/2021 report to the General Assembly. Annex C "Biological mechanisms relevant for the inference of cancer risks from low dose and low-dose rate radiation" synthesizes the current knowledge on biological mechanisms of radiation actions at low doses and low-dose-rates, and assesses the implications for understanding the processes of cancer development after exposure to ionizing radiation, and for dose-response relationships of radiation-induced cancers.

Download or read book Effects of Low Dose and Low Dose Rate Radiation written by Oddvar F. Nygaard and published by . This book was released on 1992 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 6: Effects of Low Dose and Low Dose Rate Radiation examines the biological effects of low dose and low dose rate ionizing radiation on a broad scale, covering various articles from microdosimetry to analyses of human responses. Estimates of the effects on humans from low doses or from sustained exposures to low dose rates of ionizing radiations are of critical importance for the assessment of radiation risks under occupational and environmental conditions. This book consists of such knowledge that is essential for radiation protection and governmental regu...

Download or read book Biological Radiation Effects written by Jürgen Kiefer and published by . This book was released on 1990 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Adverse Reproductive Outcomes in Families of Atomic Veterans written by Institute of Medicine and published by National Academies Press. This book was released on 1995-07-17 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past several decades, public concern over exposure to ionizing radiation has increased. This concern has manifested itself in different ways depending on the perception of risk to different individuals and different groups and the circumstances of their exposure. One such group are those U.S. servicemen (the "Atomic Veterans" who participated in the atmospheric testing of nuclear weapons at the Nevada Test Site or in the Pacific Proving Grounds, who served with occupation forces in or near Hiroshima and Nagasaki, or who were prisoners of war in or near those cities at the time of, or shortly after, the atomic bombings. This book addresses the feasibility of conducting an epidemiologic study to determine if there is an increased risk of adverse reproductive outcomes in the spouses, children, and grandchildren of the Atomic Veterans.

Download or read book Effects of Low Dose and Low Dose Rate Radiation written by Oddvar F. Nygaard and published by Academic Press. This book was released on 2013-10-22 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 6: Effects of Low Dose and Low Dose Rate Radiation examines the biological effects of low dose and low dose rate ionizing radiation on a broad scale, covering various articles from microdosimetry to analyses of human responses. Estimates of the effects on humans from low doses or from sustained exposures to low dose rates of ionizing radiations are of critical importance for the assessment of radiation risks under occupational and environmental conditions. This book consists of such knowledge that is essential for radiation protection and governmental regulatory activities pertaining to radiation exposure. This volume is intended for radiobiologists, radiation epidemiologists, radiation physicists, radiation safety personnel, health officials, and individuals involved in regulatory activities.

Download or read book Biological Effects of Radiation written by J. E. Coggle and published by Taylor & Francis Group. This book was released on 1983 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biological Effects of Low Dose Radiation written by Takeshi Yamada and published by . This book was released on 2000 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is comprised of five parts, Microdosimetry, Bystander effect and transformation, Apoptosis (cell death) and signal transduction, Adaptive responses and immune responses, Cancer and epidemiology, including a series of papers to represent the progress going on, which undoubtedly will make an important contribution to this research field. There are 22 papers ranging from the theoretical considerations, for example, "The dual response to low-dose irradiation: induction vs. prevention of DNA damage" by Dr. Feinendegen et al., in which they discussed the net dose-risk function suggesting that the incidence of cancer is less likely to be proportional to dose than to exhibit a threshold, to the experimental studies as well as to epidemiology of cancer risk of a large population lived in the area exposed to high levels of natural radiation, the Kerala coast, India. Its coverage from mice to human will make it particularly useful for students and health professionals in the fields of radiation research, health physics, environmental protection as well as regulatory control.