Download or read book Chemical and Biological Terrorism written by Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents and published by National Academies Press. This book was released on 1999-02-26 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.
Download or read book Miniature Fluidic Devices for Rapid Biological Detection written by Sang-Hyun Oh and published by Springer. This book was released on 2018-01-23 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of fundamental aspects of surface-based biosensors and techniques for enhancing their detection sensitivity and speed. It focuses on rapid detection using miniaturized sensors and describes the physical principles of nanoscale transducers, surface modifications, microfluidics and reaction engineering, diffusion and kinetics. A key challenge in the field of bioanalytical sensors is the rapid delivery of target biomolecules to the sensing surface. While various nanostructures have shown great promise in sensitive detection, diffusion-limited binding of analyte molecules remains a fundamental problem. Recently, many researchers have put forward novel schemes to overcome this challenge, such as nanopore channels, electrokinetics, and dielectrophoresis, to name but a few. This book provides the readers an up-to-date account on these technological advances.
Download or read book An introduction to biological agent detection equipment for emergency first responders written by and published by DIANE Publishing. This book was released on with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers in Biological Detection written by Amos Daniell and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Test and Evaluation of Biological Standoff Detection Systems written by National Research Council and published by National Academies Press. This book was released on 2008-07-29 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biological warfare agent (BWA) is a microorganism, or a toxin derived from a living organism, that causes disease in humans, plants, or animals or that causes the deterioration of material. The effectiveness of a BWA is greatly reduced if the attack is detected in time for the target population to take appropriate defensive measures. Therefore, the ability to detect a BWA, in particular to detect it before the target population is exposed, will be a valuable asset to defense against biological attacks. The ideal detection system will have quick response and be able to detect a threat plume at a distance from the target population. The development of reliable biological standoff detection systems, therefore, is a key goal. However, testing biological standoff detection systems is difficult because open-air field tests with BWAs are not permitted under international conventions and because the wide variety of environments in which detectors might be used may affect their performance. This book explores the question of how to determine whether or not a biological standoff detection system fulfills its mission reliably if we cannot conduct open-air field tests with live BWAs.
Download or read book Detection of Biological Agents for the Prevention of Bioterrorism written by Joseph Banoub and published by Springer Science & Business Media. This book was released on 2010-11-05 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The threat of biological and chemical terrorism has driven the demand for timely techniques that can quickly detect the agent or agents used in an attack. The detection and/or prevention of these potential security threats provide significant scientific and technical challenges due to the combination of possible agents and modes of delivery available. This book will present a thorough look at the importance and technological challenges of mass spectrometry (MS) for the detection & identification of biological and chemical threats. This new contribution’s general aims are to draw the attention of recognized practitioners, experts and graduate students trying to grasp the latest MS developments in the cutting-edge fields of MS-biodefense technologies for the rapid/early/specific sensitive threat detection of pathogens, viruses, explosives, mycotoxins, chemical agents, and biological markers of xenobiotic chemicals.
Download or read book Reactive Species Detection in Biology written by Frederick A. Villamena and published by Elsevier. This book was released on 2016-10-23 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive Species Detection in Biology: From Fluorescence to Electron Paramagnetic Resonance Spectroscopy discusses the reactive oxygen species that have been implicated in the pathogenesis of various diseases, presenting theories, chemistries, methodologies, and various applications for the detection of reactive species in biological systems, both in-vitro and in-vivo. Techniques covered include fluorescence, high performance chromatography, mass spectrometry, immunochemistry, and electron paramagnetic resonance spectroscopy. Probe design and development are also reviewed in order to advance new approaches in radical detection through synthesis, computations, or experimental applications. Reviews all current advances in radical detection Emphasizes chemical structures and reaction schemes fundamental to radical detection and identification Describes the uses, advantages, and disadvantages of various probe designs Examines new approaches to radical probe development
Download or read book Peroxynitrite Detection in Biological Media written by Serban Peteu and published by Royal Society of Chemistry. This book was released on 2015-10-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peroxynitrite is a powerful oxidiser which can damage a wide array of molecules within cells, including DNA and proteins, leading to apoptosis, inflammation or cancer. Peroxynitrite detection and quantification provides critical information in understanding its biological implications. Attempts to investigate the behavior of peroxynitrite in vivo and in vitro have been hampered by the difficulty in detecting this highly reactive oxygen species. This book presents the current state of the art in this research field with contributions from scientific leaders in the field. The chapters make clear the associated challenges and development for selective and sensitive detection of peroxynitrite. This book is a timely addition to the literature, as the first in the field, dedicated to detecting this molecule in vivo. It will be welcomed by the community particularly medicinal and analytical chemists, developers of sensors and probes and analytical equipment manufacturers.
Download or read book Frontiers in Biological Detection From Nanosensors to Systems VIII written by Benjamin L. Miller and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook on Biological Warfare Preparedness written by S.J.S. Flora and published by Academic Press. This book was released on 2019-10-05 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection
Download or read book Nanostructured Materials for the Detection of CBRN written by Janez Bonča and published by Springer. This book was released on 2018-07-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes topics in nanophysics, nanotechnology, nanomaterials, sensors, biosensors, security systems, and CBRN agents detection. There have been many significant advances in the past two years and some entirely new directions of research are just opening up. Recent developments in nanotechnology and measurement techniques now allow experimental investigation of the physical properties of nanostructured materials. The book presents new methods for the detection of chemical, biological, radiological and nuclear (CBRN) agents using chemical and biochemical sensors. Identification, protection and decontamination are the main scientific and technological responses for the modern challenges of CBRN agents.
Download or read book BioWatch and Public Health Surveillance written by National Research Council and published by National Academies Press. This book was released on 2011-01-25 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the attacks of September 11, 2001 and the anthrax letters, the ability to detect biological threats as quickly as possible became a top priority. In 2003 the Department of Homeland Security (DHS) introduced the BioWatch program-a federal monitoring system intended to speed detection of specific biological agents that could be released in aerosolized form during a biological attack. The present volume evaluates the costs and merits of both the current BioWatch program and the plans for a new generation of BioWatch devices. BioWatch and Public Health Surveillance also examines infectious disease surveillance through hospitals and public health agencies in the United States, and considers whether BioWatch and traditional infectious disease surveillance are redundant or complementary.
Download or read book Toxic Chemical and Biological Agents written by Giovanni Sindona and published by Springer Nature. This book was released on 2020-10-19 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book critically assesses the current state of knowledge on new and important detection technologies, e.g. mass spectrometry, tandem mass spectrometry, biosensor detection and tissue imaging, in connection with toxic chemical and biological agents. In general, the main topics discussed concern the risks and consequences of chemical and biological agents for human health in general, with special emphasis on all biochemical and metabolic pathways including the reproductive system. The exposome, genetic risks and the environment, various health hazard agents, risk assessment, environmental assessment and preparedness, and analysis of sub-lethal effects at the molecular level are also discussed. In closing, the book provides comprehensive information on the diagnosis of exposure, and on health concerns related to toxic chemical and biological agents.
Download or read book Existing and Potential Standoff Explosives Detection Techniques written by National Research Council and published by National Academies Press. This book was released on 2004-05-14 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Existing and Potential Standoff Explosives Detection Techniques examines the scientific techniques currently used as the basis for explosives detection and determines whether other techniques might provide promising research avenues with possible pathways to new detection protocols. This report describe the characteristics of explosives, bombs, and their components that are or might be used to provide a signature for exploitation in detection technology; considers scientific techniques for exploiting these characteristics to detect explosives and explosive devices; discusses the potential for integrating such techniques into detection systems that would have sufficient sensitivity without an unacceptable false-positive rate; and proposes areas for research that might be expected to yield significant advances in practical explosives and bomb detection technology in the near, mid, and long term.
Download or read book Review of Testing and Evaluation Methodology for Biological Point Detectors written by National Research Council and published by National Academies Press. This book was released on 2005-06-16 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report examines the proposed testing methodology and facility that the Department of Defense (DOD) will use to test and evaluate the effectiveness of its detection system against biological warfare agentsâ€"an issue that impacts battlefield missions as well as homeland security missions. The report assesses a proposal to construct a whole system live agent testing facility at West Center Test Center, Dugway Proving Ground in Utah for testing the Joint Biological Point Detection System (JBPDS). Because of scientific and schedule-related risks, the report recommends an alternate approach that focuses test and evaluation efforts on leveraging existing data, improving simulated biological agents for use in testing, testing in conditions that more closely resemble the actual field conditions where the JBPDS would be deployed, and modeling for predicted performance against actual biological agents. The report concludes that an integrated testing and evaluation plan encompassing all of these factors will be needed.
Download or read book The Detection of Biomarkers written by Sibel A. Ozkan and published by Academic Press. This book was released on 2021-12-05 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection. Locates biomarker detection in its research context, setting out present and future prospects Allows clinical researchers to compare various biomarker assays systematically Presents new methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical Gives innovative biomarker assays that are viable alternatives to current complex methods Helps clinical researchers who need reliable, precise and accurate biomarker detection methods
Download or read book Detection of Chemical Biological Radiological and Nuclear Agents for the Prevention of Terrorism written by Joseph Banoub and published by Springer. This book was released on 2014-11-03 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.
