Download or read book Bioinformatics and the Cell written by Xuhua Xia and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and biomedical sciences are becoming more interdisciplinary, and scientists of the future need inte rdisciplinary training instead of the conventional disciplinary training. Just as Sean Eddy (2005) wiselypointed out that sending monolingual diplomats to the United Nations maynot enhance international collaborations, combining strictly disciplinary scientists trained in either mathematics, computational science or molecular biology will not create a productive inte rdisciplinary team ready to solve interdisciplinary problems. Molecular biology is an interdiscip linary science back in its heyday, and founders of molecular biology were ofte n interdisciplinary scientists. Indeed, Francis Crick considered himself as “a mixture of crystallographer, biophysicist, biochemist, and geneticist” (Crick, 1965). Because it was too cumbersome to explain to people that he was such a mixture, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist, and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in each other’s problems.
Download or read book Molecular Biology Not Only for Bioinformaticians written by Wiesława Widłak and published by Springer. This book was released on 2013-12-05 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore indispensable for bioinformaticians. This book addresses beginners in molecular biology, especially computer scientists who would like to work as bioinformaticians. It presents basic processes in living organisms in a condensed manner. Additionally, principles of several high-throughput technologies in molecular biology, which need the assistance of bioinformaticians, are explained from a biological point of view. It is structured in the following 9 chapters: cells and viruses; protein structure and function; nucleic acids; DNA replication, mutations, and repair; transcription and posttranscriptional processes; synthesis and posttranslational modifications of proteins; cell division; cell signaling pathways; and high-throughput technologies in molecular biology.
Download or read book Bioinformatics for Systems Biology written by Stephen Krawetz and published by Springer Science & Business Media. This book was released on 2008-12-11 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics for Systems Biology bridges and unifies many disciplines. It presents the life scientist, computational biologist, and mathematician with a common framework. Only by linking the groups together may the true life sciences revolution move forward.
Download or read book The Digital Cell written by Stephen J. Royle and published by . This book was released on 2019 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cell biology is becoming an increasingly quantitative field, as technical advances mean researchers now routinely capture vast amounts of data. This handbook is an essential guide to the computational approaches, image processing and analysis techniques, and basic programming skills that are now part of the skill set of anyone working in the field"--
Download or read book Computational Cell Biology written by Christopher P. Fall and published by Springer Science & Business Media. This book was released on 2007-06-04 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.
Download or read book A Computer Scientist s Guide to Cell Biology written by William W. Cohen and published by Springer Science & Business Media. This book was released on 2007-07-23 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed specifically as a guide for Computer Scientists needing an introduction to Cell Biology. The text explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. The author discusses what biologists are trying to determine from their experiments, how various experimental procedures are used and how they relate to accepted concepts in computer science, and the vocabulary necessary to read and understand current literature in biology. The book is an invaluable reference tool and an excellent starting point for a more comprehensive examination of cell biology.
Download or read book A Cell Biologist s Guide to Modeling and Bioinformatics written by Raquell M. Holmes and published by John Wiley & Sons. This book was released on 2008-02-13 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A step-by-step guide to using computational tools to solve problems in cell biology Combining expert discussion with examples that can be reproduced by the reader, A Cell Biologist's Guide to Modeling and Bioinformatics introduces an array of informatics tools that are available for analyzing biological data and modeling cellular processes. You learn to fully leverage public databases and create your own computational models. All that you need is a working knowledge of algebra and cellular biology; the author provides all the other tools you need to understand the necessary statistical and mathematical methods. Coverage is divided into two main categories: Molecular sequence database chapters are dedicated to gaining an understanding of tools and strategies—including queries, alignment methods, and statistical significance measures—needed to improve searches for sequence similarity, protein families, and putative functional domains. Discussions of sequence alignments and biological database searching focus on publicly available resources used for background research and the characterization of novel gene products. Modeling chapters take you through all the steps involved in creating a computational model for such basic research areas as cell cycle, calcium dynamics, and glycolysis. Each chapter introduces a new simulation tooland is based on published research. The combination creates a rich context for ongoing skill and knowledge development in modeling biological research systems. Students and professional cell biologists can develop the basic skills needed to learn computational cell biology. This unique text, with its step-by-step instruction, enables you to test and develop your new bioinformatics and modeling skills. References are provided to help you take advantage of more advanced techniques, technologies, and training.
Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases
Download or read book Bioinformatics and the Cell written by Xuhua Xia and published by . This book was released on 2018 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition integrates the more technical and mathematical aspects of bioinformatics with concrete examples of their application to current research problems in molecular and cellular biology. This broad, unified approach is made possible, in large part, by the very wide scope of Dr. Xia's own research experience. The integration of genomics, proteomics and transcriptomics into a single volume makes this book required reading for anyone entering the new and emerging field of Systems Biology.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Biology and Bioinformatics written by Ka-Chun Wong and published by CRC Press. This book was released on 2016-04-27 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the technological advancement, but also to the companion data analytical skills and computational methods which are collectively called computational biology and bioinformatics. Without them, the biotechnology-output data by itself is raw and perhaps meaningless. To raise such awareness, we have collected the state-of-the-art research works in computational biology and bioinformatics with a thematic focus on gene regulation in this book. This book is designed to be self-contained and comprehensive, targeting senior undergraduates and junior graduate students in the related disciplines such as bioinformatics, computational biology, biostatistics, genome science, computer science, applied data mining, applied machine learning, life science, biomedical science, and genetics. In addition, we believe that this book will serve as a useful reference for both bioinformaticians and computational biologists in the post-genomic era.
Download or read book Bioinformatics and Systems Biology written by Frederick Marcus and published by Springer Science & Business Media. This book was released on 2008-07-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.
Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Download or read book The Dictionary of Cell and Molecular Biology written by John M. Lackie and published by Academic Press. This book was released on 2012-12-31 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Dictionary of Cell and Molecular Biology, Fifth Edition, provides definitions for thousands of terms used in the study of cell and molecular biology. The headword count has been expanded to 12,000 from 10,000 in the Fourth Edition. Over 4,000 headwords have been rewritten. Some headwords have second, third, and even sixth definitions, while fewer than half are unchanged. Many of the additions were made to extend the scope in plant cell biology, microbiology, and bioinformatics. Several entries related to specific pharmaceutical compounds have been removed, while some generic entries (“alpha blockers, “NSAIDs, and “tetracycline antibiotics, for example), and some that are frequently part of the experimentalist’s toolkit and probably never used in the clinic, have been retained. The Appendix includes prefixes for SI units, the Greek alphabet, useful constants, and single-letter codes for amino acids. Thoroughly revised and expanded by over 20% with over 12,000 entries in cellular and molecular biology Includes expanded coverage of terms, including plant molecular biology, microbiology and biotechnology areas Consistently provides the most complete short definitions of technical terminology for anyone working in life sciences today Features extensive cross-references Provides multiple definitions, notes on word origins, and other useful features
Download or read book Single Cell Sequencing and Systems Immunology written by Xiangdong Wang and published by Springer. This book was released on 2015-03-27 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author’s personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China.
Download or read book Bioinformatics and Computational Biology Solutions Using R and Bioconductor written by Robert Gentleman and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Download or read book Cancer Systems Biology written by Edwin Wang and published by CRC Press. This book was released on 2010-05-04 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discov
