Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book An Introduction to Biological Membranes written by William Stillwell and published by Newnes. This book was released on 2013-04-20 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. - Brings together different facets of membrane research in a universally understandable manner - Emphasis on the historical development of the field - Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport

Download or read book Membrane Transport Mechanism written by Reinhard Krämer and published by Springer Science & Business Media. This book was released on 2014-03-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a molecular view of membrane transport by means of numerous biochemical and biophysical techniques. The rapidly growing numbers of atomic structures of transporters in different conformations and the constant progress in bioinformatics have recently added deeper insights. The unifying mechanism of energized solute transport across membranes is assumed to consist of the conformational cycling of a carrier protein to provide access to substrate binding sites from either side of a cellular membrane. Due to the central role of active membrane transport there is considerable interest in deciphering the principles of one of the most fundamental processes in nature: the alternating access mechanism. This book brings together particularly significant structure-function studies on a variety of carrier systems from different transporter families: Glutamate symporters, LeuT-like fold transporters, MFS transporters and SMR (RND) exporters, as well as ABC-type importers. The selected examples impressively demonstrate how the combination of functional analysis, crystallography, investigation of dynamics and computational studies has made it possible to create a conclusive picture or more precisely, “a molecular movie”. Although we are still far from a complete molecular description of the alternating access mechanism, remarkable progress has been made from static snapshots towards membrane transport dynamics.

Download or read book Biochemistry of Membrane Transport written by I. C. West and published by Springer. This book was released on 1983-10-06 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this text is to provide students with an overview of this important and developing area of biology. The emphasis is on the biochemist's view of biological transport - discovering the molecular structures and investigating the molecular details.

Download or read book Biochemistry of Membrane Transport written by G. Semenza and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the proceedings of the FEBS Sym posium on the Biochemistry of Membrane Transport, which was held at the Swiss Institute of Technology, Zlirich, July 18-23, 1976. Of the speakers invited or iginally, only five could not attend the meeting, and of the lectures given, all but one of the texts are published here. Thus, this volume gives a faithful ac count of the way the meeting was originally conceived and actually took place. This Symposium on Biochemistry of Membrane Transport was the first Symposium sponsored by the FEBS outside the yearly FEBS-Meetings, after the Special Meeting on Industrial Biochemistry, which took place in Dublin in 1973, and it reflects the interest and the trend for gatherings of smaller size than the official FEBS Meetings. The topic of the Symposium was an easy choice, not only because membrane transport is becom ing more and more important to biochemistry every year, but also because of the long-standing interest of Swiss Science in the field. In the choice of the topics and of the speakers, efforts were made to achieve as balanced a coverage of the area as possible. However, since some aspects of membrane biochemistry were dealt with extensively at the parallel 10th Inter national Congress of Biochemistry in Hamburg, GFR, cer tain topics were given less emphasis than others. The Symposium was attended by about 400 participants (we expected 200-250); among them 48 were invited speakers, and some 200 contributed posters.

Download or read book Transport And Diffusion Across Cell Membranes written by Wilfred Stein and published by Elsevier. This book was released on 2012-12-02 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Download or read book Membrane Transport written by Daniel C. Tosteson and published by Springer. This book was released on 2013-05-27 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a fascinating collection of personal accounts which is a "must read" for anyone interested in membrane transport or the history of the development of the current picture of membrane transport physiology. This delightful book could serve variously as a history for investigators and historians or as a textbook for advanced students. No biology or medical library should be without it

Download or read book The Enzymes of Biological Membranes written by Anthony Martonosi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the first edition of The Enzymes of Biological Membranes. published in four volumes in 1976, we collected the mass of widely scattered information on membrane-linked enzymes and metabolic processes up to about 1975. This was a period of transition from the romantic phase of membrane biochemistry, preoccupied with conceptual developments and the general properties of membranes, to an era of mounting interest in the specific properties of membrane-linked enzymes analyzed from the viewpoints of modem enzymology. The level of sophistication in various areas of membrane research varied widely; the structures of cytochrome c and cytochrome b were known 5 to atomic detail, while the majority of membrane-linked enzymes had not even been isolated. In the intervening eight years our knowledge of membrane-linked enzymes ex panded beyond the wildest expectations. The purpose of the second edition of The Enzymes of Biological Membranes is to record these developments. The first volume describes the physical and chemical techniques used in the analysis of the structure and dynamics of biological membranes. In the second volume the enzymes and met abolic systems that participate in the biosynthesis of cell and membrane components are discussed. The third and fourth volumes review recent developments in active transport, oxidative phosphorylation and photosynthesis.

Download or read book Membrane Transport written by Arnost Kotyk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not many years ago, problems of membranes and transport attracted the attention of but a few dozen enthusiasts, mainly physiolo gists who recognize~ the significance of membranes for the stabilization of the general steady state of organisms. The first symposium organ ized some fifteen years ago could boast of the attendance of perhaps fifty scientists (the remaining fifty were not yet sure that membranes was the topic of their choice), ranging in specialization from physical chemistry to bacterial genetics, who clairvoyantly decided to study what now has become the number one subject at most congresses of biophysics, physiology, and even biochemistry and microbiology. As is the case with many rapidly developing fields, the interest in membranes and transport seems to be growing out of bounds and the whole field of membra no logy, interdisciplinary as it is, has penetrated into the realms of a number of branches of physics, chemistry, and biology. Its subject is primarily biological and, although much has been done in the world to increase the "exactness" of biology over the past thirty years, one cannot strive for a rigorous mathematical description of biological phenomena since, as M. H.

Download or read book Transport Across Single Biological Membranes written by D.C. Tosteson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second Volume in the series on Membrane Transport in Biology contains a group of essays on transport across single biological membranes separating the inside and outside of cells or organelles. We have not attempted to include material on all types of plasma and intracellular membranes, but rather have emphasized structures which have been studied relatively thoroughly. Four chapters describe transport of different types of molecules and ions across the plasma membranes of mammalian red cells. Two essays concern the excitable membranes of nerve and muscle cells while the remaining four chapters treat transport across several types of intracellular membranes. Water makes up more than two-thirds of the mass of most living cells. The transport of water between the inside and outside of cells and organelles is important for the function of these structures. As a result of investigations in many laboratories over the past four decades, our picture of the water permea bility of the red cell membranes is rather detailed when compared to the water permeability of other biological membranes. In Chapter 1, R. I. Macey describes this picture and also considers the permeability of red cell membranes to non electrolytes, including metabolic substrates such as sugars, amino acids, purines and nucleosides.

Download or read book Cell Membrane Transport written by Arnost Kotyk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: TO THE SECOND EDITION When preparing the manuscript for the original edition of this book we were only partly aware of the pace at which the field of membrane transport was developing and at which new ideas as well as new techniques would be applied to it. The fact is that some of the chapters are now outdated (e. g. , the one on the molecular aspects of transport) and many others require revision in the light of new information that has appeared in the past five years. However, it is also true that we overemphasized in the first edition certain points that now appear less important and underestimated the impact of certain others that have since assumed a position among the most forcefully discussed topics of membrane research. In making amends, it was thus thought useful to include the discussion of these latter problems both in the theoretical and in the comparative sections and, on the other hand, to omit some of the less topical subjects. There was a different reason for rewriting the section on kidney and for dropping the section on mito chondria. The help of an expert nephrologist was enlisted for improving chapter 24, while it was decided that mitochondria represent a special field both conceptually (being only subcellular particles) and methodologically (more indirect estimation techniques being involved than with whole cells or tissues) and that more adequate information can be found in treatises specializing in work with mitochondria.

Download or read book Cell Membrane Transport written by Z.I. Cabantchik and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental science is a complicated creature. At the head there is a Gordian knot of ideas and hypotheses; behind is the accumulated mass of decades of research. Only the laboratory methods, the legs which propel science forward, remain firmly in touch with the ground. Growth, however is uneven; dinosaurs develop by solid means to give a vast body of results, but few ideas. Others sprint briefly to success with brilliant, though ill-supported, ideas. The problems which this book addresses is to maintain an organic unity between new ideas and the current profusion of innovative experimental tools. Only then can we have the framework on which our research thoughts may flourish. The contributors are outstanding scientists in their respective fields and they record here in a clear manner the methodology with which they perform their experiments. They also illustrate some of their most exciting findings. In all chapters the emphasis is on the critical analysis of the methodology which is often avoided in refereed Journals. These techniques are explained in this book in adequate detail. Each chapter is extensively referenced and contains the most recent material available from author's laboratory at the time of going to press.

Download or read book Molecular Biology of Membrane Transport Disorders written by Thomas E. Andreoli and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.

Download or read book Membrane Biochemistry written by E. Carafoli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual collects in the form of laboratory protocols a series of experiments in the field of Membrane Transport and Membrane Bioenergetics. It represents the experience accumulated during four advanced courses held at the Depart ment of Biochemistry of the Swiss Federal Institute of Technology on behalf of Federation of European Biochemical Societies (FEBS) in the years 1975 through 1978. The idea of collecting the experiments into a laboratory manual developed as a response to a demand from the students who took part in the courses. Further motivation came with the fmding that, in planning the laboratory sessions, the teaching staff had no organized, modern source of information in the literature. The experiments presented cover most areas of importance in the subject mat ter. Their presentation has been continuously modified in the course of the four years during which the manual took shape, to accommodate to experience and various suggestions. In their present form, all of the experiments described have been repeatedly practiced to optimize their execution. Efforts have been made to combine in the manual classical experiments, and techniques which require relatively unsophisticated instrumentation and can therefore be carried out in most laboratories, with more modern experiments and relatively newer technol ogies. In its present form, the manual should therefore provide a usefui tool in the hands of researchers and laboratory teachers at different levels of sophisti cation and instrumentation.

Download or read book Channels Carriers and Pumps written by Wilfred D. Stein and published by Elsevier. This book was released on 2014-12-09 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.

Download or read book Biochemistry of Membrane Transport Proceedings written by Ernesto Carafoli and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: