Download or read book Emperor Of Enzymes A Biography Of Arthur Kornberg Biochemist And Nobel Laureate written by Errol C Friedberg and published by World Scientific. This book was released on 2016-05-18 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book chronicles the life and work of the late Arthur Kornberg, one of the premier biochemists in the world, who discovered the enzyme DNA polymerase, a key enzyme required for the biosynthesis of DNA.The book provides readers with a view of the personality and character of one of the great biochemists of the late 20th century, as well as insights into the origin and growth of the discipline of nucleic acid biochemistry, especially the biosynthesis of DNA.The book consists of 17 chapters that trace the life and work of Arthur Kornberg.

Download or read book The Recombinant University written by Doogab Yi and published by University of Chicago Press. This book was released on 2015-03-23 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of recombinant DNA technology in the 1970s was a key moment in the history of both biotechnology and the commercialization of academic research. Doogab Yi’s The Recombinant University draws us deeply into the academic community in the San Francisco Bay Area, where the technology was developed and adopted as the first major commercial technology for genetic engineering. In doing so, it reveals how research patronage, market forces, and legal developments from the late 1960s through the early 1980s influenced the evolution of the technology and reshaped the moral and scientific life of biomedical researchers. Bay Area scientists, university administrators, and government officials were fascinated by and increasingly engaged in the economic and political opportunities associated with the privatization of academic research. Yi uncovers how the attempts made by Stanford scientists and administrators to demonstrate the relevance of academic research were increasingly mediated by capitalistic conceptions of knowledge, medical innovation, and the public interest. Their interventions resulted in legal shifts and moral realignments that encouraged the privatization of academic research for public benefit. The Recombinant University brings to life the hybrid origin story of biotechnology and the ways the academic culture of science has changed in tandem with the early commercialization of recombinant DNA technology.

Download or read book Biochemistry at Stanford Biotechnology at DNAX written by and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biotechnology written by Nico Stehr and published by Routledge. This book was released on 2017-09-08 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: "While other books have addressed isolated aspects of recent developments in the biomedical sciences, Biotechnology: Between Commerce and Civil Society is the first book tgo engage with the full range of biotechnology's implications for social science and for society at large." -Professor Volker Meja New scientific knowledge is no longer merely the key to unlocking the secrets of nature and society. It now represents the "becoming" of a new world. Scientific developments affect the ways in which we conduct our affairs, as well as how we comprehend the changes underway as the result of novel technical artefacts and scientific knowledge. The practical fruits of biotechnology are a case in point; they have grasped our imaginations, and generated worldwide debate and concern. Debates on biotechnology shift between images of utopia and dystopia. The social sciences deserve a voice in the debate, and can do so through sober examination of the economic, social, and cultural implications of biotechnology. Some economists even predict that the importance of biotechnology as the technology of the future will far exceed that of the information technologies, in particular the Internet. The contributors to this volume are drawn from a broad spectrum of the social sciences, and include Nico Stehr, Gene Rosa, Steve Fuller, Steve Best and Douglas Kellner, Nikolas Rose, Fred Buttel, Javier Lezaun, Anne Kerr, Susanna Hornig Priest and Toby Ten Eyck, Martin Schulte, Alexander Somek, Steven P. Vallas, Daniel Lee Kleinman, Abby Kinchy and Raul Necochea, Herbert Gottweis, J. Rogers Hollingsworth, Gysli Pblsson, Elizabeth Ettore, Richard Hindmarch and Reiner Grundmann. The impact of science on society is destined to be a fundamental concern in the new century. This volume illustrates the contributions anthropology, law, political science, and sociology can make to the ongoing discussions about the role of biotechnology in modern societies. Nico Stehr is senior research associate, Institut for Technikfolgenabschotzung, Forschungszentrum Karlsruhe and Institut for Kostenforschung, GKSS, Germany. He also is a fellow in the Center for Advanced Cultural Studies in Essen, Germany, editor of the Canadian Journal of Sociology, and a fellow of the Royal Society of Canada. Among his recent books are Werner Sombart: Economic Life in the Modern Age (with Reiner Grundmann, published by Transaction); The Fragility of Modern Societies: Knowledge and Risk in the Information Age; Knowledge and Economic Conduct: The Social Foundations of the Modern Economy; and Wissenspolitik: Die ?berwachung des Wissens.

Download or read book Biotech written by Eric J. Vettel and published by University of Pennsylvania Press. This book was released on 2013-03-01 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seemingly unlimited reach of powerful biotechnologies and the attendant growth of the multibillion-dollar industry have raised difficult questions about the scientific discoveries, political assumptions, and cultural patterns that gave rise to for-profit biological research. Given such extraordinary stakes, a history of the commercial biotechnology industry must inquire far beyond the predictable attention to scientists, discovery, and corporate sales. It must pursue how something so complex as the biotechnology industry was born, poised to become both a vanguard for contemporary world capitalism and a focal point for polemic ethical debate. In Biotech, Eric J. Vettel chronicles the story behind genetic engineering, recombinant DNA, cloning, and stem-cell research. It is a story about the meteoric rise of government support for scientific research during the Cold War, about activists and student protesters in the Vietnam era pressing for a new purpose in science, about politicians creating policy that alters the course of science, and also about the release of powerful entrepreneurial energies in universities and in venture capital that few realized existed. Most of all, it is a story about people—not just biologists but also followers and opponents who knew nothing about the biological sciences yet cared deeply about how biological research was done and how the resulting knowledge was used. Vettel weaves together these stories to illustrate how the biotechnology industry was born in the San Francisco Bay area, examining the anomalies, ironies, and paradoxes that contributed to its rise. Culled from oral histories, university records, and private corporate archives, including Cetus, the world's first biotechnology company, this compelling history shows how a cultural and political revolution in the 1960s resulted in a new scientific order: the practical application of biological knowledge supported by private investors expecting profitable returns eclipsed basic research supported by government agencies.

Download or read book Economics and Management in the Biopharmaceutical Industry in the USA written by Rachel Kim and published by Routledge. This book was released on 2018-12-07 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: From a managerial perspective, the biopharmaceutical industry represents a competitive, fast-changing, intellectually-powered, innovation-driven sector. Many management scholars have studied this discontinuous era to make sense of strategic behavior and the cognition of firms and top managers. A past look at the biopharmaceutical industry provides answers to questions that most managers have. For example, what options do you have and what actions do you take when new firms enter your industry? In the 1970s, new biotechnology firms, funded by venture capitalists, appeared in the pharmaceutical industry with new knowledge. Successful pharmaceutical firms decided to collaborate with the new entrants and forge relationships to develop and create new, biotechnology engineered drugs. Thus, the addition of new biotechnology firms ushered in a new business model based on strategic alliances. Strategic alliances have now become an industrial norm called open innovation. The author looks at the historical path of the biopharmaceutical industry, particularly in the United States. While the pharmaceutical industry’s main contributions to society are substantial, there are pressing challenges the industry must face, such as an increase in infectious disease outbreaks or the global aging population, which require new types of care, additionally, mental health care and prescription painkiller addiction are persistent issues with economic repercussions to both federal and local governments. This book presents a holistic view of the biopharmaceutical industry, putting it in a historical context. It will best serve those who are eager to learn about this dynamic, fast-evolving industry and who would like to tackle current biopharmaceutical industry issues in the United States and be prepared for future industry challenges.

Download or read book Watson And DNA written by Viktor K. McElheny and published by Basic Books. This book was released on 2009-03-25 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most influential scientist of the last century, James Watson has been at dead center in the creation of modern molecular biology. This masterful biography brings to life the extraordinary achievements not only of Watson but also all those working on this cutting edge of scientific discovery, such as Walter Gilbert, Francis Crick, Francois Jacob, and David Baltimore. From the ruthless competition in the race to identify the structure of DNA to a near mutiny in the Harvard biology department, to clashes with ethicists over issues in genetics, Watson has left a wake of detractors as well as fans. Victor McElheny probes brilliantly behind the veil of Watson's own invented persona, bringing us close to the relentless genius and scientific impresario who triggered and sustained a revolution in science.

Download or read book Biomedicine in the Twentieth Century written by Caroline Hannaway and published by IOS Press. This book was released on 2008 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: ." . . based on a conference that was held at the National Institutes of Health in December 2005 to promote historical research on biomedical science in the twentieth century"--p. ix.

Download or read book Creating the Market University written by Elizabeth Popp Berman and published by Princeton University Press. This book was released on 2012-01-08 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Academic science in the U.S. once self-consciously avoided the market. But today it is seen as an economic engine that keeps the nation globally competitive. Creating the Market University compares the origins of biotech entrepreneurship, university patenting, and university-industry research centers to show how government decisions shaped by a new argument--that innovation drives the economy-transformed academic science"-- Provided by publisher.

Download or read book Arthur Kornberg M D written by Arthur Kornberg and published by . This book was released on 1998 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A to Z of Biologists written by Lisa Yount and published by Infobase Publishing. This book was released on 2014-05-14 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Profiles more than 150 scientists from around the world who made important contributions to the field of biology, including Claude Bernard, Alexander Fleming, Mary-Claire King, Ronald Ross, and Tetsuko Takabe.

Download or read book Historical Studies in the Physical and Biological Sciences written by and published by . This book was released on 2004 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genes Germs And Medicine The Life Of Joshua Lederberg written by Jan Sapp and published by World Scientific. This book was released on 2021-02-23 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes, Germs and Medicine explores the development of modern biomedical science in the United States through the life of one of the Twentieth Century's most influential scientists.Joshua Lederberg was a scientific renaissance man. He and his collaborators founded the field of bacterial genetics, and he was awarded the Nobel Prize at the age of 33 (the second youngest in history). He helped to lay the foundations for genetic engineering, made fundamental revisions to immunological and evolutionary theory, and developed medical genetics. He initiated the search for extraterrestrial microbial life, developed artificial intelligence, and was a visionary of the Digital Age. Lederberg coined some of the central terms of modern biology: plasmid, transduction, exobiology, euphenics and microbiome.A complex humanist who spoke out for social justice, Lederberg confronted racism, and denied a gene-centered view of humans. Pondering our social evolution outside of nature, he forewarned of the complex ethical issues arising from bioengineering. He sounded the alarm about coming pandemics at a time when few would listen, and warned of the peril of biowarfare and strove to prevent it. Lederberg was a man with a deep sense of social and intellectual responsibility, a trusted advisor to eight presidential administrations.

Download or read book The Emergence of Organizations and Markets written by John F. Padgett and published by Princeton University Press. This book was released on 2012-10-14 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: A dynamic framework for studying social emergence The social sciences have sophisticated models of choice and equilibrium but little understanding of the emergence of novelty. Where do new alternatives, new organizational forms, and new types of people come from? Combining biochemical insights about the origin of life with innovative and historically oriented social network analyses, John Padgett and Walter Powell develop a theory about the emergence of organizational, market, and biographical novelty from the coevolution of multiple social networks. They demonstrate that novelty arises from spillovers across intertwined networks in different domains. In the short run actors make relations, but in the long run relations make actors. This theory of novelty emerging from intersecting production and biographical flows is developed through formal deductive modeling and through a wide range of original historical case studies. Padgett and Powell build on the biochemical concept of autocatalysis—the chemical definition of life—and then extend this autocatalytic reasoning to social processes of production and communication. Padgett and Powell, along with other colleagues, analyze a very wide range of cases of emergence. They look at the emergence of organizational novelty in early capitalism and state formation; they examine the transformation of communism; and they analyze with detailed network data contemporary science-based capitalism: the biotechnology industry, regional high-tech clusters, and the open source community.

Download or read book Recombinant DNA Methodology written by and published by Academic Press. This book was released on 2014-05-19 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recombinant DNA methods are powerful, revolutionary techniques that allow the isolation of single genes in large amounts from a pool of thousands or millions of genes and the modification of these isolated genes or their regulatory regions for reintroduction into cells for expression at the RNA or protein levels. These attributes lead to the solution of complex biological problems and the production of new and better products in the areas of medicine, agriculture, and industry. Recombinant DNA Methodology, a volume in the Selected Methods in Enzymology series produced in benchtop format, contains a selection of key articles from Volumes 68, 100, 101, 153, 154, and 155 of Methods in Enzymology. The essential and widely used procedures provided at an affordable price will be an invaluable aid to the graduate student and the researcher. - Enzymes in DNA research - DNA isolation, hybridization, and cloning - DNA sequence analysis - cDNA cloning - Gene products - Identification of cloned genes and mapping of genes - Monitoring cloned gene expression - Cloning and transferring of genes into yeast cells - Cloning and transferring of genes into plant cells - Cloning and transferring of genes into animal cells - Site-directed mutagenesis - Protein engineering - Expression vectors

Download or read book Science and the American Century written by Sally Gregory Kohlstedt and published by University of Chicago Press. This book was released on 2013-03-14 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: The twentieth century was one of astonishing change in science, especially as pursued in the United States. Against a backdrop of dramatic political and economic shifts brought by world wars, intermittent depressions, sporadic and occasionally massive increases in funding, and expanding private patronage, this scientific work fundamentally reshaped everyday life. Science and the American Century offers some of the most significant contributions to the study of the history of science, technology, and medicine during the twentieth century, all drawn from the pages of the journal Isis. Fourteen essays from leading scholars are grouped into three sections, each presented in roughly chronological order. The first section charts several ways in which our knowledge of nature was cultivated, revealing how scientific practitioners and the public alike grappled with definitions of the “natural” as they absorbed and refracted global information. The essays in the second section investigate the changing attitudes and fortunes of scientists during and after World War II. The final section documents the intricate ways that science, as it advanced, became intertwined with social policies and the law. This important and useful book provides a thoughtful and detailed overview for scholars and students of American history and the history of science, as well as for scientists and others who want to better understand modern science and science in America.

Download or read book Qualitative Organizational Research Volume 3 written by Beth A. Bechky and published by IAP. This book was released on 2016-02-01 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Davis Conference on Organizational Research, held for the last 15 years, is the world’s leading conference for qualitative researchers in organizational studies. Scholars receiving the “Best presentation awards” at the Davis Conference for the past 6 years have contributed chapters to this volume. These papers explore social relationships in organizations and work, and cover a diverse set of topics ranging from boundary spanning in collaboration and teamwork to embodied competence at work and beliefs about availability among professionals. Yet all the papers are similar in that they benefited from the community of over 150 scholars developed through the Davis Conference, and represent qualitative research at its very best.