Download or read book Concepts in Biochemical Pharmacology written by Bernard B. Brodie and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the Handbook of Experimental Pharmacology (Concepts in Biochemical Pharmacology) will show that pharma cology has finally arrived as a true discipline in its own right, and is no longer the handmaiden of organic chemistry and physiology. Instead it is an amalgam of all the biological sciences including biochemistry, biophysical chemistry, physiology, pathology and clinical medicine. In the volumes that make up Concepts in Bio chemical Pharmacology we hope to convince Medical Schools what should now be obvious, that pharmacology is no longer that dull topic bridging the basic sciences with medicine, but is probably the most important subject in the medical curriculum. We are grateful for the advice of Dr. Byron Clark, Director of the Pharmacology-Toxicology Program at the National Institutes of Health whose support made possible much of the work described in this volume. Contents Section Four: Methods 01 Stooging the MetoholiBm 01 Drugs Subsection A. Assay 01 Drugs and Their M etoholites Chapter 22 : Basic Principles in Development of Methods for Drug Assay. B. B. BRODIE. With 2 Figures 1 1 A. Introduction . . . . . . . . . . B. Principles of Developing a Method. . . . . . 1 I. Section of Method of Assay . . . . . . 1 II. Choice of Solvent for Extraction of Drug 2 III. Adsorption of Drugs by Glass Surfaces . . . . . . . . . . . . . . 3 IV. Recoveries of Known Amounts of Compound from Biological Material. 4 V. Assessment of Sensitivity 5 VI. Assessment of Specificity 5 References. . . . . . . . . . .
Download or read book Biochemistry for Clinical Medicine written by Ira Thabrew and published by Cambridge University Press. This book was released on 2001 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry for Clinical Medicine integrates, in a single volume, all aspects of biochemistry required by a medical student.
Download or read book Basic and Clinical Pharmacology 15e written by Bertram G. Katzung and published by McGraw Hill Professional. This book was released on 2020-11-22 with total page 1326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master key pharmacological concepts and practices with the most comprehensive, authoritative guide available Doody's Core Titles for 2023! Presented in full-color and packed with hundreds of illustrations, Basic and Clinical Pharmacology is the wide-ranging, engaging guide students have counted on for decades. Organized to reflect the course sequence in many pharmacology courses and in integrated curricula, the guide covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. This edition has been extensively updated to provide expanded coverage of transporters, pharmacogenomics, and new drugs Delivers the knowledge and insight needed to excel in every facet of pharmacology!. Encompasses all aspects of medical pharmacology, including botanicals and over-the-counter drugs Major revisions of the chapters on immunopharmacology, antiseizure, antipsychotic, antidepressant, antidiabetic, anti-inflammatory, and antiviral drugs, prostaglandins, and central nervous system neurotransmitters New chapter on the increasingly relevant topic of cannabis pharmacology Each chapter opens with a case study, covers drug groups and prototypes, and closes with summary tables and diagrams that encapsulate important information Revised full-color illustrations provide more information about drug mechanisms and effects and help clarify important concepts Trade Name/Generic Name tables are provided at end of each chapter for easy reference when writing a chart order or prescription Includes descriptions of important new drugs released through May 2019 New and updated coverage of general concepts relating to recently discovered receptors, receptor mechanisms, and drug transporters
Download or read book Biochemistry for the Pharmaceutical Sciences written by Charles P. Woodbury and published by Jones & Bartlett Publishers. This book was released on 2012 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry for the Pharmaceutical Sciences is a concise, practical resource for pharmacy students to apply and expand their understanding of biochemistry as it relates to pharmacy practice. With pedagogical features designed to make complex concepts comprehensible, this text presents biochemistry in a clear and comprehensible format with a pharmaceutical focus. Real-world applications of scientific principles allow students to better comprehend and appreciate how biochemistry will impact their professional practice. Chapter Features • Learning Objectives • Glossary of Key Terms • Clinical Application Boxes • Discussion Questions Includes over 400 figures and tables to help students formulate an understanding of the mathematical, chemical, and biological concepts. Instructor Resources: PowerPoint Slides, Image Bank
Download or read book Clinical Pharmacology written by Desmond Roger Laurence and published by . This book was released on 1997 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the rational scientific basis and practice of drug therapy. Doctors need to understand the psychological and medical area in which they prescribe to deliver what patients have a right to expect, ie. maximum benefit with minimum risk.
Download or read book Atkinson s Principles of Clinical Pharmacology written by Shiew-Mei Huang and published by Academic Press. This book was released on 2021-10-16 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Download or read book Fundamentals of Biochemistry Medical Course and Step 1 Review written by David DiTullio and published by McGraw Hill Professional. This book was released on 2018-11-02 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The biochemistry/USMLE® review you’ve been waiting for . . . clear, concise, high yield, and clinically relevant INCLUDES AN ONLINE VIDEO LECTURE FOR EVERY CHAPTER! The goal of Fundamentals of Biochemistry: Medical Course & Step 1 Review is to make biochemistry an approachable, clinically relevant subject for your first years of medical school, and, most importantly, when you prepare to take the USMLE® Step 1 examination. The authors believe that when biochemistry is put in a clinical context, learning and understanding it becomes much less complicated, as all the pieces of the “puzzle” fall into place. A SELF-CONTAINED, HIGH-YIELD GUIDE UNLIKE ANY OTHER You will find Fundamentals of Biochemistry: Medical Course & Step 1 Review to be a self-contained guide to high-yield biochemistry, with a strong focus on the topics you are most likely to see on the USMLE® Step 1 exam. You can select any chapter and find a self-contained summary of the relevant topic. The authors begin with the basics of the cell and DNA, and protein synthesis, then cover the central aspects of metabolism, and finish with nutrition and genetics. EASY-TO-ABSORB CHAPTERS ENHANCED BY COMPANION ONLINE VIDEOS The information is delivered in a simple outline format that pinpoints the high-yield information you need to know. Each chapter is also presented as a lecture, in video format, so you can review the topic in real time and add additional notes as you learn each topic or review them later.
Download or read book Basic and Clinical Pharmacology written by Bertram G. Katzung and published by . This book was released on 2001 with total page 1217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.
Download or read book Principles of Clinical Pharmacology written by Arthur J. Atkinson Jr. and published by Elsevier. This book was released on 2011-04-28 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. - Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy - Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course - Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study - Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry - Expanded coverage of pharmacogenetics - Expanded coverage of drug transporters and their role in interactions - Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions - A new chapter on drug discovery that focuses on oncologic agents - Inclusion of therapeutic antibodies in chapter on biotechnology products
Download or read book Biochemical Pharmacology written by Michael Palmer and published by John Wiley & Sons. This book was released on 2012-04-09 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated approach to the study of drug action mechanisms Biochemical Pharmacology is a concise and contemporary textbook on the principles of drug action. It discusses representative drugs by example to explore the range of biochemical targets and mechanisms. The book explains some of the experiments that tell us how drugs work, and it outlines the physiological and pathological context that make those action mechanisms therapeutically useful. Biochemical Pharmacology is intended primarily for students in biology and biochemistry at the advanced undergraduate or graduate levels. For classroom use, the illustrations from the book are separately available as PowerPoint slides. It is written in a conversational, vivid style that readily encourages students to explore this important area of medical science. Biochemical Pharmacology can also serve as an introduction for professionals in biosciences, as well as in pharmaceutical and health sciences. Complete with numerous figures throughout the text, which are also available separately as PowerPoint slides, Biochemical Pharmacology: Explains the role of pharmacodynamics, pharmacokinetics, and drug metabolism in drug action Provides representative examples from the pharmacology of cell excitation, hormones, nitric oxide, chemotherapy, and others Examines emerging applications of ribonucleic acids as drugs and drug targets Discusses what researchers need to know about the problems of drug distribution, elimination, and toxicity Biochemical Pharmacology is an important resource for anyone wishing to gain an in-depth understanding of drug action mechanisms and extremely useful for researchers wishing to explore some of the unanswered questions .
Download or read book Caffeine for the Sustainment of Mental Task Performance written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-07 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report from the Committee on Military Nutrition Research reviews the history of caffeine usage, the metabolism of caffeine, and its physiological effects. The effects of caffeine on physical performance, cognitive function and alertness, and alleviation of sleep deprivation impairments are discussed in light of recent scientific literature. The impact of caffeine consumption on various aspects of health, including cardiovascular disease, reproduction, bone mineral density, and fluid homeostasis are reviewed. The behavioral effects of caffeine are also discussed, including the effect of caffeine on reaction to stress, withdrawal effects, and detrimental effects of high intakes. The amounts of caffeine found to enhance vigilance and reaction time consistently are reviewed and recommendations are made with respect to amounts of caffeine appropriate for maintaining alertness of military personnel during field operations. Recommendations are also provided on the need for appropriate labeling of caffeine-containing supplements, and education of military personnel on the use of these supplements. A brief review of some alternatives to caffeine is also provided.
Download or read book Biochemical Basis of Medicine written by Eric D. Wills and published by Butterworth-Heinemann. This book was released on 2014-04-24 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Basis of Medicine discusses academic biochemistry and the applications of biochemistry in medicine. This book deals with the biochemistry of the subcellular organelles, the biochemistry of the body , and of the specialized metabolism occurring in many body tissues. This text also discusses the various applications of biochemistry as regards environmental hazards, as well as in the diagnosis of illnesses and their treatment. This text explains the structure of the mammalian cell, the cell's metabolism, the nutritional requirements of the whole body, and the body's metabolism. This book explains the specialized metabolisms involved in tissues such as those occurring in blood clotting, in the liver during carbohydrate metabolism, or in the kidneys during water absorption. The text explains toxicology or biochemical damage caused by excess presence of copper, mercury, or lead in the body. Chelation therapy can remove these toxic metals. This book describes the effects of alcohol on plasma liquids, the multistage concept of carcinogenesis, and the biochemical basis of diagnosis. Diagnosis and treatment include the determination of typical enzymes found in the plasma, tests for genetic defects in blood proteins, and the use of chemotherapeutic drugs. This book is suitable for chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology.
Download or read book Biochemical Targets of Plant Bioactive Compounds written by Gideon Polya and published by CRC Press. This book was released on 2003-05-15 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.
Download or read book Natural Products written by Goutam Brahmachari and published by Alpha Science International, Limited. This book was released on 2009 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products provides an insight into significant developments in some of the promising areas of natural products chemistry. Natural products are of great interest and promise in the present day research directed towards drug design and discovery. This book brings together leading scientists of the world, an overview of current discoveries and trends in this remarkable field. The topics, ranging from natural products chemistry and phytochemistry in their most basic form to molecular biology, pharmacology and in silico drug design, summarize years of extensive research in each area, and provide insight in the new themes of natural products research. The book serves as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations; it also motivates young scientists to the dynamic field of bioactive natural products research.
Download or read book Casebook in Clinical Pharmacokinetics and Drug Dosing written by Henry Cohen and published by McGraw Hill Professional. This book was released on 2014-10-06 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS Casebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes. Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including: Indications Mec hanisms of action Toxicities Pharmacokinetics There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.
Download or read book Quality and Safety in Pharmacy Practice written by Terri L. Warholak and published by McGraw Hill Professional. This book was released on 2010-05-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gain a complete understanding of the principles of quality improvement and their application to present and future pharmacy practice "This book is a great resource for pharmacists and pharmacy students who want to learn about safety and quality in pharmacy practice."--Laura Cranston, RPh, Executive Director, The Pharmacy Quality Alliance Quality and Safety in Pharmacy Practice details the principles, approaches, strategies, and actions necessary to improve the overall safety and effectiveness of pharmacy services. Although one of the book’s primary goals is to enhance the quality of future health care, you will find guidelines that can be implemented immediately to improve today’s pharmacy practice. This comprehensive text offers a complete overview of quality in general, the reasons for improving practice, and actual day-to-day changes and approaches that will positively impact the patient. Quality and Safety in Pharmacy Practice is divided into five parts, covering: The current and future landscape of health care quality and the business case for quality improvement and value-driven health care Quality improvement concepts and tools, including statistical process control Quality and safety measurement, including mechanisms for gathering consumer feedback Incentives and other drivers of quality improvement Application of the principles of quality improvement to pharmacy practice -- complete with case examples
Download or read book The Organic Chemistry of Medicinal Agents written by Adam Renslo and published by McGraw Hill Professional. This book was released on 2015-11-23 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most concise and streamlined textbook available on organic chemistry for the pharmacy student Organic Chemistry for Pharmacy is a textbook written specifically for the students taking the required Organic/Medical Pharmacy course. Using a building-block approach, the book delivers a basic, yet thorough discussion of the mode of action, therapeutic applications, and limitations of various pharmaceutical agents. Organic Chemistry for Pharmacy is especially written for students who have a limited background in chemistry. In order to make the learning/teaching experience as efficient as possible, Organic Chemistry for Pharmacy includes outstanding pedagogical features such as chapter outlines, chapter summaries, boxed “take away points”, quick-reference tables, and problems within each chapter. The focus and presentation of this text is particularly suited for Organic/Medical Pharmacy courses which are weighted heavily towards Organic, rather than Medical Pharmacy.
