Download or read book Biochemical and Clinical Aspects of Oxygen written by Winslow S. Caughey and published by . This book was released on 1979 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Biochemical and Clinical Aspects of Oxygen written by Winslow Caughey and published by Elsevier. This book was released on 2012-12-02 with total page 887 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical and Clinical Aspects of Oxygen contains the proceedings of a symposium held on the Pingree Park Campus of Colorado State University on September 24-29, 1978. Contributors discuss the biochemical and clinical aspects of oxygen, focusing on reactions and areas relating to heme, flavin, copper and nonheme iron proteins, organ transplants, carbon monoxide formation and detoxification, oxidant drugs and pollutants, oxygen toxicity, enzyme inactivation, lipid peroxidation, membrane destruction, antioxidants, cataractogenesis, mutagen and carcinogen formation, malaria and trypanosome parasites, and inflammation. This volume is organized into 51 chapters and begins with a discussion of bonding and reactions of dioxygen bound to hemeproteins, along with the pathophysiology of hemolysis due to unstable hemoglobins. The focus then turns to the reactivity and function of leghemoglobin, reduction of oxygen and five redox forms of horseradish peroxidase, and acid-base catalysis and hydrogen bonding in reactions mediated by peroxidases. The reader is methodically introduced to the ligands of cytochrome P-450 and their role in the activation of dioxygen, oxygen and catabolite regulation of hemoprotein biosynthesis in yeast, and factors controlling hemoprotein reactivity. A chapter describing the spectroscopic mapping of oxygen supply and demand in the heart concludes the book. This book will be of interest to biochemists, biophysicists, physicians, toxicologists, immunologists, physiologists, parasitologists, radiologists, and environmentalists.
Download or read book Textbook of Hyperbaric Medicine written by Kewal K. Jain and published by Springer. This book was released on 2016-11-25 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume captures the latest scientific evidence, technological advances, treatments and impact of biotechnology in hyperbaric oxygen therapy. Divided into three distinct sections, the book begins with basic aspects that include history, equipment, safety and diagnostic approaches; this is followed by clinical applications for hyperbaric oxygen therapy in various modalities; the last section provides an overview of hyperbaric medicine as a specialty with best practices from around the world. Integration of multidisciplinary approaches to complex disorders are also covered. Updated and significantly expanded from previous editions, Textbook of Hyperbaric Medicine, 6th Edition will continue to be the definitive guide to this burgeoning field for students, trainees, physicians and specialists.
Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
Download or read book The Elements A Very Short Introduction written by Philip Ball and published by Oxford University Press. This book was released on 2004-04-08 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Very Short Introduction is an exciting and non-traditional approach to understanding the terminology, properties, and classification of chemical elements. It traces the history and cultural impact of the elements on humankind from ancient times through today. Packed with anecdotes, The Elements is a highly engaging and entertaining exploration of the fundamental question: what is the world made from?
Download or read book Monitoring and Intervention for the Critically Ill Small Animal written by Rebecca Kirby and published by John Wiley & Sons. This book was released on 2016-12-19 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monitoring and Intervention for the Critically Ill Small Animal: The Rule of 20 offers guidance for assessing the patient, interpreting diagnostic test results, and selecting appropriate monitoring procedures. Based on Rebecca Kirby’s time-tested Rule of 20, with a chapter devoted to each item on the checklist Provides comprehensive guidance for monitoring a critically ill small animal patient Emphasizes the interplay of each parameter with one another Designed for fast access on the clinic floor, with potentially life-saving ideas, tips, lists and procedures Presents tables, schematics, algorithms, and drawings for quick reference
Download or read book Biochemical and Clinical Aspects of Hemoglobin Abnormalities written by Winslow Caughey and published by Elsevier. This book was released on 2012-12-02 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical and Clinical Aspects of Hemoglobin Abnormalities contains the proceedings of a symposium held on the Pingree Park campus of Colorado State University on October 2-7, 1977. Contributors discuss the biochemical and clinical aspects of hemoglobin abnormalities and cover topics ranging from amino acid substitutions to sickle cell disease, glycosylated hemoglobins, cystamine inhibition of sickling, and gelation of sickle cell hemoglobin. This volume is organized into 52 chapters and begins with a discussion of the role of distal residues in structure, ligand binding, and oxidation of hemoglobins A, Zurich, and Sydney. It then turns to functional abnormalities of whole blood in sickle cell anemia, inhibition of sickle hemoglobin gelation by amino acids and peptides, and intermolecular interactions in crystals of human deoxy hemoglobins A, C, F, and S. The chapters that follow focus on glycosylation of human hemoglobin, the phase transitions of sickle-cell hemoglobin, conformational effects of the HbS mutation, and mechanisms for hemoglobin oxidation. The reader is also introduced to oxidation of oxyhemoglobin by reductants, the kinetics of oxygen binding to human red blood cells, and oxidation of human hemoglobin by copper. A chapter that assesses the effect of physiological parameters, such as pH, oxygen concentration, protein concentration, non-gelling hemoglobins, and the erythrocyte membrane, on the kinetics of polymerization of deoxyhemoglobin S concludes the book. This book is intended for biochemists and clinicians interested in knowing more about hemoglobin abnormalities.
Download or read book Common Surgical Diseases written by Jonathan A. Myers and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a concise manner, this book presents common surgical problems encountered by medical students and residents. The book provides easy access for residents before teaching rounds, lectures, etc. The algorithm approach lends itself to rapid learning, making the book a must for every surgical resident.
Download or read book Compartment Syndrome written by Cyril Mauffrey and published by Springer Nature. This book was released on 2019-09-02 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compartment syndrome is a complex physiologic process with significant potential harm, and though an important clinical problem, the basic science and research surrounding this entity remains poorly understood. This unique open access book fills the gap in the knowledge of compartment syndrome, re-evaluating the current state of the art on this condition. The current clinical diagnostic criteria are presented, as well as the multiple dilemmas facing the surgeon. Pathophysiology, ischemic thresholds and pressure management techniques and limitations are discussed in detail. The main surgical management strategy, fasciotomy, is then described for both the upper and lower extremities, along with wound care. Compartment syndrome due to patient positioning, in children and polytrauma patients, and unusual presentations are likewise covered. Novel diagnosis and prevention strategies, as well as common misconceptions and legal ramifications stemming from compartment syndrome, round out the presentation. Unique and timely, Compartment Syndrome: A Guide to Diagnosis and Management will be indispensable for orthopedic and trauma surgeons confronted with this common yet challenging medical condition.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Medical Biochemistry The Big Picture written by Lee W. Janson and published by McGraw Hill Professional. This book was released on 2012-03-25 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the BIG PICTURE of Medical Biochemistry – and target what you really need to know to ace the course exams and the USMLE Step 1 300 FULL-COLOR ILLUSTRATIONS Medical Biochemistry: The Big Picture is a unique biochemistry review that focuses on the medically applicable concepts and techniques that form the underpinnings of the diagnosis, prognosis, and treatment of medical conditions. Those preparing for the USMLE, residents, as well as clinicians who desire a better understanding of the biochemistry behind a particular pathology will find this book to be an essential reference. Featuring succinct, to-the-point text, more than 300 full-color illustrations, and a variety of learning aids, Medical Biochemistry: The Big Picture is designed to make complex concepts understandable in the shortest amount of time possible. This full-color combination text and atlas features: Progressive chapters that allow you to build upon what you’ve learned in a logical, effective manner Chapter Overviews that orient you to the important concepts covered in that chapter Numerous tables and illustrations that clarify and encapsulate the text Sidebars covering a particular disease or treatment add clinical relevance to topic discussed Essay-type review questions at the end of each chapter allow you to assess your comprehension of the major topics USMLE-style review questions at the end of each section Three appendices, including examples of biochemically based diseases, a review of basic biochemical techniques, and a review of organic chemistry/biochemistry
Download or read book Human Hemoglobins written by Howard Franklin Bunn and published by W.B. Saunders Company. This book was released on 1977 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the dawn of the era of molecular biology, hemoglobin has been subjected to more scrutiny than any other protein, and Bunn, Forget, and Ranney can each lay claim to major contributions to the saga of hemoglobin. Their well-organized, comprehensive, and superbly illustrated work is an excellent review of the abnormal hemoglobin field. Early chapters deal with the structure and function of human hemoglobin and the way in which this is modified in various disease states. Later sections deal with the various structural hemoglobin variants and their associated clinical manifestations, the thalassaemias, and the acquired disorders of hemoglobin. The sections that deal with the modification of hemoglobin function in various disease states are particularly good. The book contains an extensive and up-to-date bibliography and is remarkably free from errors of fact or type--the best standard of reference on the subject as of the year 1977.
Download or read book Wound Healing written by I. Kelman Cohen and published by Saunders. This book was released on 1992 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents comprehensive up-to-date discussions of both clinical and basic science aspects of wound healing. This text enables the reader to obtain information from several different scientific disciplines and clinical specialities in one place.
Download or read book Hemoglobin Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics written by Hae Won Kim and published by Springer Science & Business Media. This book was released on 2013-12-18 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.
Download or read book Oxygen Transport to Tissue XXV written by Maureen S. Thorniley and published by Springer Science & Business Media. This book was released on 2003-12-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 30th scientific meeting of the International Society on Oxygen Transport to Tissue (ISOTT) was held at the Western Conference Centre, UMIST, Manchester, in August 2002. It was attended by some 96 delegates and accompanying persons and there were 128 presentations.
Download or read book Toxicology of Cyanides and Cyanogens written by Alan H. Hall and published by John Wiley & Sons. This book was released on 2015-10-13 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic and applied toxicology of cyanides and cyanogens has widespread commercial, occupational, environmental, clinical, forensic, military, and public health implications. This book provides a detailed and updated reference describing the properties, uses, general and human toxicology, clinical recognition, diagnosis and medical management, and countermeasures is therefore required in academic, medical, occupational, environmental, medico-legal, regulatory, emergency response, and military arenas. Edited by a world-renowned team of experts from academia, defense and industry, this book will be an invaluable reference for professionals, researchers and students in cyanide and cyanogens.
