Download or read book Bio Engineered Meniscus for Tissue Engineering written by Azran Azhim and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meniscus plays fundamental roles in the knee mechanisms and functions. It acts as a shock absorber where it enables even distribution of forces, and also lubricates knee joints. Meniscal injuries could result to the onset of degenerative osteoarthritis if proper treatments are delayed. To date, treatment of meniscal injuries are more towards conservative methods and surgical approach commonly known as meniscectomy. Attempts to develop scaffolds for meniscus implants from synthetic and biological sources have been done in the recent years. This approach involves a multidisciplinary study known as tissue engineering and regenerative medicine. It involves the combination of three crucial aspects; the choice of chondrogenic/stem cells, bioscaffolds and favourable environmental factors such as growth factors. This chapter discusses and highlights on the currently available meniscal scaffolds that have been explored before. Focus is also directed on the potential of decellularized extracellular matrix (ECM), prepared through sonication treatment that produced scaffolds which mimics natural meniscus. The evaluation of decellularized scaffolds was portrayed through recellularization using cells namely chondrocytes, fibrochondrocytes and stem cells in order to regenerate new functional tissue. In short, this chapter serves as a representation of current approaches aiming in bio-engineering the meniscal scaffolds as meniscus tissue replacement.
Download or read book Engineering the Knee Meniscus written by Kyriacos A. Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2009 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: The knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications. Table of Contents: Structure-Function Relationships of the Knee Meniscus / Pathophysiology and the Need for Tissue Engineering / Tissue Engineering of the Knee Meniscus / Current Therapies and Future Directions
Download or read book Sports Injuries written by Mahmut Nedim Doral and published by Springer Nature. This book was released on 2015-06-29 with total page 3295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sports Injuries: Prevention, Diagnosis, Treatment and Rehabilitation covers the whole field of sports injuries and is an up-to-date guide for the diagnosis and treatment of the full range of sports injuries. The work pays detailed attention to biomechanics and injury prevention, examines the emerging treatment role of current strategies and evaluates sports injuries of each part of musculoskeletal system. In addition, pediatric sports injuries, extreme sports injuries, the role of physiotherapy, and future developments are extensively discussed. All those who are involved in the care of patients with sports injuries will find this textbook to be an invaluable, comprehensive, and up-to-date reference.
Download or read book Functional Tissue Engineering written by Farshid Guilak and published by Springer Science & Business Media. This book was released on 2003-07-09 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: -Softcover reprint of a successful hardcover reference (370 copies sold) -Price to be accessible to the rapidly increasing population of students and investigators in the field of tissue engineering -Chapters written by well-known researchers discuss issues in functional tissue engineering as well as provide guidelines and a summary of the current state of technology
Download or read book The Meniscus written by Philippe Beaufils and published by Springer Science & Business Media. This book was released on 2010-04-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide focuses on the normal meniscal mechanism, body and function. Meniscal pathology and therapy are depicted in detail, followed by a presentation of long-term experience of meniscal transplantation and a look into the future of meniscal surgery.
Download or read book Magnetic Resonance Imaging in Tissue Engineering written by Mrignayani Kotecha and published by John Wiley & Sons. This book was released on 2017-02-21 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging in Tissue Engineering provides a unique overview of the field of non-invasive MRI assessment of tissue engineering and regenerative medicine Establish a dialogue between the tissue-engineering scientists and imaging experts and serves as a guide for tissue engineers and biomaterial developers alike Provides comprehensive details of magnetic resonance imaging (MRI) techniques used to assess a variety of engineered and regenerating tissues and organs Covers cell-based therapies, engineered cartilage, bone, meniscus, tendon, ligaments, cardiovascular, liver and bladder tissue engineering and regeneration assessed by MRI Includes a chapter on oxygen imaging method that predominantly is used for assessing hypoxia in solid tumors for improving radiation therapy but has the ability to provide information on design strategies and cellular viability in tissue engineering regenerative medicine
Download or read book The Menisci written by Robert F. LaPrade and published by Springer. This book was released on 2017-02-21 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive journey through the pathogenesis and treatment of meniscal pathology. It details the elements that are necessary to properly understand, diagnose, and treat meniscal tears, ranging from vertical tears to radial tears and root avulsions. Treatment techniques are thoroughly described and illustrated, with presentation of the latest evidence on outcomes. The algorithmic treatment of meniscal tears has undergone a rapid transformation. We have progressed from the initial treatments involving removal of the meniscus using an open technique, to the performance of partial meniscectomies and complex meniscal repairs by means of an arthroscopic technique. The current treatment goal is to maintain the biology and mechanical integrity of this vital knee structure, an aim too often disregarded by past generations of surgeons. An explosion of new knowledge, coupled with advances in arthroscopic and surgical technology, has paved the way for wider application of approaches that help to preserve the meniscus, in the hope of preventing or delaying the development of knee arthritis. This book will have utility for all clinicians who treat meniscal lesions and will serve as a valuable resource for years to come.
Download or read book Musculoskeletal Tissue Regeneration written by William S. Pietrzak and published by Springer Science & Business Media. This book was released on 2008-04-11 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.
Download or read book 3D Printing in Medicine written by Deepak M. Kalaskar and published by Woodhead Publishing. This book was released on 2022-10-18 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand. Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more
Download or read book Biomaterials for Tissue Engineering Applications written by Jason A. Burdick and published by Springer Science & Business Media. This book was released on 2010-12-07 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: (i) general materials technology (e.g., fibrous tissue scaffolds) and (ii) applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field.
Download or read book Stem Cell Repair And Regeneration Volume 2 written by Nagy A Habib and published by World Scientific. This book was released on 2007-03-06 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second book in the Stem Cell Repair and Regeneration series provides a deeper exploration of the therapeutic potential of undifferentiated human stem cells.Regenerative medicine is an extremely fast-moving field which is evolving from the initial days of hype and excitement to a more realistic appraisal of the role of stem cells in the treatment of degenerative disorders. The series aims to keep abreast of these changes by combining new knowledge in stem cell biology and therapeutic applications.The current volume contains papers by the field's leading scientists and explores the current knowledge on cell therapy for different diseases and injured organs, including diabetes, liver and heart disease./a
Download or read book Meniscus of the Knee written by Taiceer Abdulwahab and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The principal aim of this title is to provide the arthroscopic orthopaedic surgeon with a clear, concise account of the anatomy, pathology, conservative and operative surgical techniques in the management of meniscal pathology. Meniscal lesions are extremely common, and arthroscopic meniscal surgery is one of the most common orthopaedic surgical procedures performed. The art of meniscal surgery involves many steps, with ever-evolving techniques and implants. This book has been prepared during a period of widespread debate on, and evolution in, the conservative, surgical, and biological techniques for managing meniscal lesions. This text will help consolidate the current evidence to enable the development of optimal management plans for meniscal injuries.
Download or read book Frontiers in Tissue Engineering written by C.W. Patrick and published by Elsevier. This book was released on 1998-02-20 with total page 717 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field. The book is divided into three parts: fundamentals and methods of tissue engineering, tissue engineering applied to specialised tissues, and tissue engineering applied to organs. The text offers many novel approaches, including a detailed coverage of cell-tissue interactions at cellular and molecular levels; cell-tissue surface, biochemical, and mechanical environments; biomaterials; engineering design; tissue-organ function; new approaches to tissue-organ regeneration and replacement of function; ethical considerations of tissue engineering; and government regulation of tissue-engineered products.
Download or read book Articular Cartilage Tissue Engineering written by Kyriacos A. Athanasiou and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions
Download or read book Biodegradable Polymers in Clinical Use and Clinical Development written by Abraham J. Domb and published by John Wiley & Sons. This book was released on 2011-05-12 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.
Download or read book Articular Cartilage written by Kyriacos A. Athanasiou and published by CRC Press. This book was released on 2013-03-21 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Well-known for their inability to heal, articular cartilage injuries often degenerate inexorably to disastrous impairment. Multitudes of treatments have been devised for this problem, but no satisfactory long-term solutions have been established. Written by world-class experts, Articular Cartilage covers the latest research and advancements related to biology, development, pathology, clinical applications, and tissue engineering. This book is useful for rheumatologists, orthopaedic surgeons, cartilage biologists, and cartilage engineers as well as for professionals working in the orthopaedic and other musculoskeletal industries. This book also belongs in the library of primary care physicians, gerontologists, physical therapists, kinesiologists, and chiropractors. Written at a level that allows accessibility to a wide audience, it provides an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering, translational science, and detailed methodologic approaches. The authors examine the major events and signaling molecules that lead to development of articular cartilage from precursor cells, and the changes in cartilage as it matures and ages. They focus on the epidemiology, etiopathogenesis, and therapeutic approaches for cartilage injury and the major arthritides that affect cartilage and the synovial joints such as osteoarthritis, rheumatoid arthritis, and gout. They supply an up-to-date overview of the field of tissue engineering as applied to articular cartilage repair. They examine a number of methods used to assess structure, composition, biology, and biomechanical function. Each chapter contains extensive references to enhance additional study. The book’s comprehensive focus on multiple aspects of articular cartilage sets it apart from other tissue engineering or developmental biology-based books available. It includes important discussions and perspectives on many of the remaining challenges and opportunities in the development and translation of new approaches for treating diseases of articular cartilage. It also provides detailed working protocols for many of the methods used to study articular cartilage, coverage of current treatment options, and business and regulatory aspects of the development of cartilage products. It provides a deeper understanding that will help with the development of new products and clinical applications.
Download or read book Fundamentals of Tissue Engineering and Regenerative Medicine written by Ulrich Meyer and published by Springer Science & Business Media. This book was released on 2009-02-11 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fundamentals of Tissue Engineering and Regenerative Medicine" provides a complete overview of the state of the art in tissue engineering and regenerative medicine. Tissue engineering has grown tremendously during the past decade. Advances in genetic medicine and stem cell technology have significantly improved the potential to influence cell and tissue performance, and have recently expanded the field towards regenerative medicine. In recent years a number of approaches have been used routinely in daily clinical practice, others have been introduced in clinical studies, and multitudes are in the preclinical testing phase. Because of these developments, there is a need to provide comprehensive and detailed information for researchers and clinicians on this rapidly expanding field. This book offers, in a single volume, the prerequisites of a comprehensive understanding of tissue engineering and regenerative medicine. The book is conceptualized according to a didactic approach (general aspects: social, economic, and ethical considerations; basic biological aspects of regenerative medicine: stem cell medicine, biomolecules, genetic engineering; classic methods of tissue engineering: cell, tissue, organ culture; biotechnological issues: scaffolds; bioreactors, laboratory work; and an extended medical discipline oriented approach: review of clinical use in the various medical specialties). The content of the book, written in 68 chapters by the world’s leading research and clinical specialists in their discipline, represents therefore the recent intellect, experience, and state of this bio-medical field.
