Download or read book Behavioral Neurobiology of Huntington s Disease and Parkinson s Disease written by Hoa Huu Phuc Nguyen and published by Springer. This book was released on 2015-05-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
Download or read book Parkinson s Disease and Movement Disorders written by Joseph Jankovic and published by Lippincott Williams & Wilkins. This book was released on 2015-04-03 with total page 1301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trusted as the leading text in the field, Parkinson's Disease and Movement Disorders, 6th Edition, brings you fully up to date with new developments in this rapidly-changing subspecialty. International experts provide thorough coverage of basic science and clear guidance for your day-to-day clinical challenges – from innovative medical and surgical treatments to new drug delivery systems and recent discoveries in genetics, plus much more. In addition, an extensive online video atlas demonstrates movement and posture abnormalities, as well as unique and unusual phenomenology. Get comprehensive, current information on every aspect (including behavioral and psychologic concomitants) of all common and uncommon movement disorders, including Parkinson's disease, other neurodegenerative diseases, tremors, dystonia, Tourette's syndrome, Huntington's disease, and ataxias. Focus on the new discoveries you need to know about: the role of ubiquitin-proteosome and autophagy systems in neurodegeneration; genetics of Parkinson’s disease and other movement disorders; innovative medical and surgical treatment of Parkinson’s disease and hyperkinetic movement disorders; and more. Stay up to date with new information on autoimmune disorders, novel deliveries of drugs, and new formulations of botulinum toxin. Benefit from access to an outstanding online video library (with dozens of new videos) that demonstrate what you’re likely to see in practice and key elements to look for. Instantly view videos online with your tablet or smartphone, thanks to new QR codes inserted throughout the text.
Download or read book Neuropsychiatry and Behavioral Neuroscience written by Jeffrey L. Cummings and published by Oxford University Press. This book was released on 2003-01-23 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the long-awaited successor to Jeffrey Cummings' classic work, Clinical Neuropsychiatry, published in 1985. That book represented an integration of behavioral neurology and biological psychiatry into a single volume devoted to explicating brain-behavior relationships. It was clinically oriented and intended for practitioners caring for patients with neuropsychiatric disorders. The new title reflects the authors' effort to link the recent explosion of new information from neurochemistry, neuroanatomy, genetics, neuropharmacology, neuropathology, and neuroimaging to the clinical descriptions. Yet the clinical emphasis of its predecessor has been maintained. Each chapter has a consistent approach and the book as whole provides a practical, easy-to-use synthesis of clinical advice and basic science. The volume is enhanced by 4-color images throughout. It is intended for students, residents, fellows, and practitioners of neurology, psychiatry, neuropsychology, and cognitive neuroscience. It will also be of interest to individuals in neuroimaging.
Download or read book Genetics Neurology Behavior and Diet in Parkinson s Disease written by Colin R Martin and published by Academic Press. This book was released on 2020-08-13 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson’s Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease
Download or read book The Neuroscience of Parkinson s Disease written by Colin R Martin and published by Academic Press. This book was released on 2020-12-21 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neuroscience of Parkinson’s Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease
Download or read book Central Nervous System Diseases written by Dwaine F. Emerich and published by Springer Science & Business Media. This book was released on 1999-11-24 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases. Coverage includes novel uses of animal models of Alzheimer's, Parkinson's, and Huntington's diseases, and studies of aging. Techniques that rely heavily on behavioral analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated, as are models developed for more acute neurological conditions, including traumatic brain injury and stroke. Comprehensive and authoritative, Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic offers neuroscientists, pharmacologists, and interested clinicians a unique survey of the most productive animal models of the leading neurological diseases currently employed to develop today's innovative drug therapies.
Download or read book The Neuropathology of Huntington s Disease Classical Findings Recent Developments and Correlation to Functional Neuroanatomy written by Udo Rüb and published by Springer. This book was released on 2015-09-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
Download or read book Movement Disorders written by A.G. Donald and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human nervous system-that most complex organization of energy and matter-has yielded a few glimmers of understanding of its operational me chanics during the last two decades. These have mostly been at the biochemical level of structure and function. Throughout history, as one of the mysteries of nature begins to yield some insights into its function, it has been beneficial to look at it from different points of view. We have developed a volume on movement disorders that is primarily directed toward the biochemical understanding of these disorders and their treatment. Each disorder is presented from several points of view. Although this approach leads to some repetition, it is our aim that the final outcome be a more complete understanding. Much has been written about movement: the beauty of the prima ballerina, the strength of the olympic athlete, and the agility of the surgeon. Seldom do we stop to look beneath the surface-the coordination of muscle groups, the finely tuned balance allowing rapid response in either direction, the individual muscle fibers coordinated to maximize strength and agility, and the nerve fibers connecting muscle with nerve centers. Some of these communicate sensory input of position to the centers while others communicate directions of move ment to muscles. We encourage our readers to be constantly alert to the possibility of in creasing their understanding of other nervous system functions, including thought disorder, through an understanding of movement, either in general principle or by specific chemical interaction.
Download or read book The Basal Ganglia VI written by International Basal Ganglia Society. Symposium and published by Springer Science & Business Media. This book was released on 2003-03-31 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of the Sixth TriennialMeeting of the International Basal Ganglia Society, held in Brewster, Massachusetts from October 15-18, 1998. This volume focuses on thefunctions of the basal ganglia in health and disease and the neuralmechanisms that underpin these functions. This book is useful foranyone in the field of neuroscience, neuropharmacology, neurobiology, neuroanatomy and neurophysiology.
Download or read book Brain Mind and Behavior Study Guide written by Joyce Norman and published by Macmillan. This book was released on 2000-09-22 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This carefully crafted study guide helps students to read and retain text material, and provides them with a multitude of learning tools. The Study Guide includes new labeling exercises of important physiological and neurological structures. Each chapter includes a review of key concepts, guided study questions, practice tests and section reviews that encourage students' active participation in the learning process.
Download or read book The Complete MRCPsych written by Ashok Patel and published by CRC Press. This book was released on 2006-01-27 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studying for the MRCPsych exams can seem a daunting prospect, especially when faced with the vast amounts of literature available to help, but this book offers a complete solution in the form of a thoroughly comprehensive guide to the Part I Exam. Completely up to date and taking in the recent changes to the exam, the book reflects the exam format and content extremely accurately. Written by an experienced examiner with contributions from trainees, the book combines these elements to ensure that it is the perfect revision companion for any psychiatrist preparing for the MRCPsych Part I.
Download or read book The Basal Ganglia VIII written by International Basal Ganglia Society. Symposium and published by Springer Science & Business Media. This book was released on 2005-12-21 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the International Meetings of the Basal Ganglia Society (IBAGS) is to provide a unique environment for the open presentation and discussion of new and challenging information about the basal ganglia as it relates to health and disease, covering all areas of basic science and research. Specific topics of the proceedings of this Eighth International Triennial Meeting of the Basal Ganglia Society include behavior, circuitry, functional imaging, modelling, movement disorders, neuropathology, neurotransmitters, pharmacology, physiology, plasticity, treatments for basal ganglia disorders, ventral systems, health and disease, immunology and basal ganglia, and much more.
Download or read book The Basal Ganglia IX written by Hendrik Jan Groenewegen and published by Springer. This book was released on 2012-02-25 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the International Basal Ganglia Society (IBAGS) is to further our understanding of normal basal ganglia function and the pathophysiology of disorders of the basal ganglia, including Parkinson's disease, Huntington's disease, and schizophrenia. Each triennial meeting of IBAGS brings together basic research scientists from all disciplines as well as clinicians who are actively involved in the treatment of basal ganglia disorders, to discuss the most recent advances in the field and to generate new approaches and ideas for the future. This volume comprises the proceedings of the 9th meeting of IBAGS, held in Egmond aan Zee, The Netherlands, September 2nd-6th, 2007.
Download or read book Handbook of Basal Ganglia Structure and Function written by Heinz Steiner and published by Academic Press. This book was released on 2010-03-17 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases
Download or read book Behavioral Neurology of Movement Disorders written by Karen E. Anderson and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised to reflect the latest advances in treatment and research, this volume is the most comprehensive, current clinical reference on psychiatric symptoms associated with movement disorders. This edition's expanded section on Parkinson's disease includes new chapters on anxiety disorders; sleep disorders, sexual dysfunction, apathy, and other neuropsychiatric complications; behavioral side effects of newer medications; and behavioral changes following deep brain stimulation and ablative surgery. Also included is a chapter discussing Parkinson's disease as a model for psychosocial issues in chronic neurodegenerative disease. Other new chapters cover behavioral concomitants of ataxias, essential tremor, dystonias, Creutzfeldt-Jakob disease, and autoimmune neuropsychiatric disorders.
Download or read book Neuropathology of Neurodegenerative Diseases written by Gabor G. Kovacs and published by Cambridge University Press. This book was released on 2017-12-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.
Download or read book Handbook of the Behavioral Neurobiology of Serotonin written by and published by Academic Press. This book was released on 2020-01-23 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Behavioral Neurobiology of Serotonin, Second Edition, builds on the success of the first edition by continuing to provide a detailed and comprehensive overview of the many facets of behavioral serotonin research. The text expands on the two key topics, behavioral control (sensory processing, ultrasonic vocalization, and melatonin and sleep control) and psychiatric disorders, including its role on psychostimulant abuse and addiction. The new edition includes two new sections on the serotonin systems interactions and the involvement of serotonin in neurological disorders and associated treatment. Serotonin is a major neurotransmitters in the serotonergic system which one of the best studied and understood transmitter systems. Both are critically involved in the organization of all behaviors and in the regulation of emotion and mood. Features two new sections on serotonin systems interactions and serotonin in neurological disorders Focuses on ionotropic and metabotropic 5-HT receptor involvement in behavior Maps receptors and receptor signaling pathways to neurochemical and behavioral outcomes Covers the interactions between serotonin, melatonin and kynurenine pathways
