Download or read book Behavioral Neurobiology of Anxiety and Its Treatment written by Murray B. Stein and published by Springer Science & Business Media. This book was released on 2010-07-30 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is part of a series on Current Topics in Behavioral Neurosciences, which has as its focus anxiety and its treatment. We have brought together a distinguished cadre of authors with the aim of covering a broad array of topics related to anxiety disorders, ranging from clinical diagnosis, epidemiology, preclinical neuroscience, and animal models to established and innovative therapeutic approaches. The book aims at bridging these disciplines to provide an update of literature relevant to understanding anxiety, its consequences, and its management. Following is a brief overview of the chapters and their content, meant to serve as a guide to navigating the book. The ?rst section covers clinical aspects of anxiety disorders. Joe Bienvenu and colleagues provide an incisive overview of diagnostic considerations in the anxiety disorders in which they emphasize the strengths and shortcomings of our current nosologic systems. This is followed by a review and update of the epidemiology of anxiety disorders by Ron Kessler and colleagues, which provides an authoritative survey of anxiety disorder incidence, prevalence, and risk factors. This is comp- mented by a comprehensive review of the literature on disorders that co-occur with anxiety disorders by Kathleen Merikangas and Sonja Alsemgeest Swanson. Their review highlights the tremendous comorbidity that occurs not only within the anxiety disorders, but also with other mental and physical health conditions.

Download or read book Behavioral Neurobiology of Anxiety and Its Treatment written by Murray B. Stein and published by . This book was released on 2010-09-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Behavioral Neurobiology of Stress related Disorders written by Carmine M. Pariante and published by Springer. This book was released on 2014-11-11 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress is such an over-used word that it is at time difficult to define its core features. When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels. Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects. The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress. Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior.

Download or read book Handbook of Anxiety and Fear written by D. Caroline Blanchard and published by Elsevier. This book was released on 2011-09-02 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning in response to threat. These patterns are stringently selected, providing a close fit with environmental situations and events; they are highly conservative across mammalian species, producing important similarities, along with some systematic differences, in their human expression in comparison to that of nonhuman mammals. These patterns are described, with attention to both adaptive and maladaptive components, and related to new understanding of neuroanatomic, neurotransmitter, and genetic mechanisms. Although chapters in the volume acknowledge important differences in views of fear and anxiety stemming from animal vs. human research, the emphasis of the volume is on a search for an integrated view that will facilitate the use of animal models of anxiety to predict drug response in people; on new technologies that will enable direct evaluation of biological mechanisms in anxiety disorders; and on strengthening the analysis of anxiety disorders as biological phenomena. Integrates animal and human research on fear and anxiety Presents emerging and developing fields of human anxiety research including imaging of anxiety disorders, the genetics of anxiety, the pharmacology of anxiolysis, recent developments in classification of anxiety disorders, linking these to animal work Covers basic research on innate and conditioned responses to threat Presents work from the major laboratories, on fear learning and extinction Reviews research on an array of neurotransmitter and neuromodulator systems related to fear and anxiety Compares models, and neural systems for learned versus unlearned responses to threat Relates the findings to the study, diagnostics, and treatment of anxiety disorders, the major source of mental illness in modern society (26 % of Americans are affected by anxiety disorders!)

Download or read book Behavioral Neurobiology of PTSD written by Eric Vermetten and published by Springer. This book was released on 2018-08-25 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the behavioral neuroscience that supports our understanding of the neurobiology of trauma risk and response. The collection of articles focuses on both preclinical and clinical reviews of (1) state-of-the-art knowledge of mechanisms of posttraumatic stress disorder (PTSD) and co-occurring disorders, (2) the biological and psychological constructs that support risk and resiliency for trauma disorders, and (3), novel treatment strategies and therapeutics on the horizon.

Download or read book Behavioral Neurobiology of Depression and Its Treatment written by Philip J. Cowen and published by Springer Science & Business Media. This book was released on 2014-04-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research.

Download or read book Behavioral Neurobiology of Bipolar Disorder and its Treatment written by Husseini K. Manji and published by Springer Science & Business Media. This book was released on 2010-11-10 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Download or read book Encyclopedia of Behavioral Neuroscience written by and published by Elsevier. This book was released on 2010-06-03 with total page 1819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people’s lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities. Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases. The only comprehensive Encyclopedia of Behavioral Neuroscience on the market Addresses all recent advances in the field Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders Richly illustrated in full color Extensively cross referenced to serve as the go-to reference for students and researchers alike The online version features full searching, navigation, and linking functionality An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists

Download or read book The Neurobiology and Treatment of OCD Accelerating Progress written by Naomi A. Fineberg and published by Springer Nature. This book was released on 2021-07-20 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights important new research approaches of clinical relevance, written by prominent researchers in the field of OCD and related disorders. A broad range of topics is covered, beginning with a description of the phenotypic features of the OCD followed by chapters on developmental aspects, animal models, genetic and biological models including neuro-inflammation, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered including clinical and pharmacogenetic treatment models. In this way the volume brings together the key disciplines involved in the neurobiological understanding of OCD to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators and clinicians interested in the present state of OCD research.

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Download or read book Behavioral Neurobiology of Bipolar Disorder and its Treatment written by Husseini K. Manji and published by Springer. This book was released on 2011-04-08 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Download or read book Anxiety Disorders written by Brian F. Shaw and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anxiety is one of those entltles which everyone "knows", but which ultimately resists simple objective description. The essence of the phenomenon is its subjectivity. True it has its well documented associated physiological events: the increased pulse rate and blood pressure, sweating, and so on, but each of these phenomena may also be part of physical exertion, fear, or even pleasurable excitement. They cannot fully define the sense of threat, danger, collapse, malignancy in greater or smaller amount, in greater or lesser locali sation, with more or less objective evidence for its validity that characterises the particular psychological pain we all recognize as anxiety. It is precisely the essential subjectivity of anxiety and its association with an enormous range of experience that makes it difficult to assign to it well-defined diagnostic labels of the kinds so carefully described by Dr. Spitzer in his chapter on classification. His chapter ranges from the extreme dread of "Panic Disorders", to the diffuse terror of the environment which used to be labelled "Agoraphobia" (and is still so called in the day to day pragmatic usage of many clinics) and is not assimilated to the class of phobias with the label "Social Phobias". He also addresses the "Simple Phobias" which are perhaps the most readily labelled of the many varieties of anxiety.

Download or read book Panic Disorder written by Antonio Egidio Nardi and published by Springer. This book was released on 2016-05-25 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on the neurobiological and treatment aspects of panic disorder. It describes the most recent research data and pharmacological therapeutic aspects of panic disorder. The biochemical, respiratory, imaging, and translational aspects will be together with diagnostic and pharmacological discussion. We have the collaboration of important and recognized researchers from various countries – Brazil, USA, Italy, Spain, United Kingdom, and Switzerland – all of them with a continuous and relevant work on anxiety disorders. "Panic Disorder: Neurobiological and Treatment Aspects" is intended to be a reference book for those who research or treat panic disorder and anxiety disorder patients.

Download or read book New Developments in Anxiety Disorders written by Federico Durbano and published by BoD – Books on Demand. This book was released on 2016-12-07 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects the contribution of a selected number of clinical psychiatrists, interested in the clinical application of some aspects of neurobiology of anxiety. The seven chapters of the book address some issues related to the latest acquisitions of neurobiology, in particular those aspects that are related to responses to treatment - both psychological and pharmacological. Some chapters are also dedicated to the comorbidities, a rule rather than an exception when it comes to anxiety. Each author summarized the clinical importance of his work, underlining the clinical pitfalls of this new book on anxiety.

Download or read book Neurobiological Models of Psychotherapy How Psychotherapy Changes the Brain written by Arash Javanbakht and published by Frontiers Media SA. This book was released on 2019-09-25 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fear and Anxiety written by Jack M. Gorman and published by American Psychiatric Pub. This book was released on 2008-05-20 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals, like people, experience fear and avoidance, which can be reliably observed, quantified, and manipulated in almost all species. Remarkably, as this volume demonstrates, the neural circuits responsible for the acquisition and expression of fear are conserved throughout phylogeny from rodents through nonhuman primates to humans. Thus, what is discovered about the neuroanatomy and physiology of fear in a mouse can be usefully "translated" to a human with an anxiety disorder. This breakthrough in both neuroscience and mental health research is detailed in 14 fascinating chapters that cover Conditioned fear -- Many scientists have convincingly documented that the amygdala is the essential brain structure in an animal's exhibition of conditioned fear, with the hippocampus required for contextual memory of conditioned fear. Though debate continues, other studies show that the anatomic and physiological findings about conditioned fear are robustly applicable to other forms of fear. The brain structures involved in fear -- The data clearly show that the amygdala is the one area most consistently energized in fear responses of nonhuman and human primates. Patients with anxiety disorders have a lower threshold for amygdala activation than do control subjects; thus, fear cues that do not register an amygdala response in most individuals will do so in anxious patients. Stress effects on brain structure -- It is possible that, based on both animal studies and clinical studies of children and adults, chronic exposure to fear may have deleterious effects on the structural integrity of the brain. The hippocampus appears to be particularly vulnerable, though stress damage may also occur in regions of the prefrontal cortex, such as the anterior cingulate. The results of translational research can raise concerns that observed negative changes in animal brains might apply to humans, but they can also suggest advantageous interventions, with both psychosocial and psychopharmacology approaches proving effective in reversing not only anxiety disorders but even some changes in the brain. Best of all, using these scientific models of brain function, we can now see psychotherapy and medication as complementary rather than antagonistic, with each addressing different parts of the same fear circuitry. The synthesis of knowledge in this groundbreaking work will appeal to practitioners and students alike, and justifies the optimism of its distinguished contributors that psychiatric research is at last in an era in which unprecedented insights will be gained and progress made toward better treatments.

Download or read book Serotonin and Anxiety written by Caio Maximino and published by Springer. This book was released on 2012-05-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anxiety disorders have long been a research subject for scientists in different areas of inquiry, and the particular role of serotonin – the neurotransmitter which has probably most captured the imagination of laymen and academics alike – is as elusive as the clinical aspects of serotonergic medications. Why are drugs acting at certain serotonin receptors efficacious against generalized anxiety disorder, but not panic disorder? Why is the inverse true for monoamine oxidase inhibitors? These clinically relevant issues are clarified by the neurochemical, anatomical and physiological organization of the serotonergic system. In this book, the author summarizes the latest findings regarding the role of serotonin in modulating the activity of brain regions which organize behavioral patterns associated with fear, anxiety and stress. The emergent picture is one of far greater complexity than previously thought: while the serotonergic innervation of those brain regions arises from the same structure – the dorsal raphe nucleus – that structure is not homogeneous from anatomical, physiological and neurochemical points of view, nor are its projections to the cerebral aversive and behavioral inhibition systems. The diverse findings which compose this picture of complexity – whether they arise from developmental neurobiology, electrophysiology, neurochemistry, neuroendocrinology, neuropsychopharmacology or behavioral neuroscience – are integrated in this book. Advanced undergraduate, graduate students, and researchers will benefit from the information. The result sheds light on many important questions regarding the neuroanatomical, pharmacological and functional aspects of the role of serotonin in anxiety disorders, and points to future avenues of research.