Download or read book Basics of Medical Molecular Biology written by Tarek H. El-Metwally and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology is a merger between biochemistry and genetics that undertakes the study of the molecular fundamentals of metabolism of the genetic material (i.e.: replication, the transcription and translation and its manipulation for the benefit of life). Molecular biology is the molecular three-dimensional structural studying approach of biology as reflected on genesis and function to search below the large-scale manifestations of classical biology. The recent merge of molecular biology and computer science developed bioinformatics and computational biology. The study of gene structure and function, i.e., molecular genetics, is amongst the most prominent sub-field of molecular biology. This book highlights the rationale behind most of the related diseases afflicting the nuclear and the mitochondrial genetic systems for specific prevention and/or intervention.
Download or read book Molecular Biology in Medicine written by Timothy M. Cox and published by Wiley-Blackwell. This book was released on 1997-05-12 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text fuses science and medicine, clearly demonstrating the clinical relevance of microbiology, and the way in which this rapidly emerging discipline is beginning to reshape the way disease is investigated and how patients are screened, diagnosed and treated. The first part of the book summarises knowledge of basic cell biology with clear and lucid descriptions of how genes work and how the study of human variation and heredity is applied to medical practice. A detailed analysis of Heamophilia A provides a paradigm for the use of molecular biology in the study and treatment of inherited disease. The second section takes the reader through the systematic approaches to studying genes, and provides an entry point for clinicians and researchers who wish to investigate a disease themselves or interpret the experiments of others. The third section shows how molecular biology has been used in medical research to investigate the mechanisms of common diseases; and the final section identifies areas where molecular biology has been used to diagnose and treat disease. It looks at the principles and practice of gene therapy and the design and production of recombinant products for medical use. The book closes with a description of how molecular biology has impinged upon prenatal diagnosis, and the ethical considerations which this raises.
Download or read book Basic Methods in Molecular Biology written by Leonard G. Davis and published by . This book was released on 1992 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this popular book emphasizes the decisions that need to be made to select one procedure over another.
Download or read book Molecular Biology A Very Short Introduction written by Aysha Divan and published by Oxford University Press. This book was released on 2016-08-18 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology is the story of the molecules of life, their relationships, and how these interactions are controlled. It is an expanding field in life sciences, and its applications are wide and growing. We can now harness the power of molecular biology to treat diseases, solve crimes, map human history, and produce genetically modified organisms and crops, and these applications have sparked a multitude of fascinating legal and ethical debates. In this Very Short Introduction, Aysha Divan and Janice Royds examine the history, present, and future of Molecular Biology. Starting with the building blocks established by Darwin, Wallace and Mendel, and the discovery of the structure of DNA in 1953, they consider the wide range of applications for Molecular Biology today, including the development of new drugs, and forensic science. They also look forward to two key areas of evolving research such as personalised medicine and synthetic biology. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Download or read book Molecular Biology written by David P. Clark and published by Elsevier. This book was released on 2012-03-20 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology, Second Edition, examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This updated edition includes Focuses on Relevant Research sections that integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world. The new Academic Cell Study Guide features all the articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text. Animations provided deal with topics such as protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE. The text also includes updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA. An updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images. This text is designed for undergraduate students taking a course in Molecular Biology and upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry, and Agriculture. NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images Fully revised art program
Download or read book Lashley s Essentials of Clinical Genetics in Nursing Practice Second Edition written by Christine E. Kasper, PhD, RN, FAAN, FACSM and published by Springer Publishing Company. This book was released on 2015-09-16 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely updated to help nurses learn to ìthink geneticallyî Todayís nurses must be able to ìthink geneticallyî to help individuals and families who are affected by genetic disease or contemplating genetic testing. This book is a classic resource for nursing students and practitioners at all levels who need to acquire the knowledge and skills for using genomics in their practice. This completely updated second edition encompasses the many recent advances in genetic research and knowledge, providing essential new information on the science, technology, and clinical application of genomics. It focuses on the provision of individualized patient care based on personal genetics and dispositions. The second edition is designed for use by advanced practice nursing programs, as well as undergraduate programs. It pinpoints new developments in prenatal, maternity, and pediatric issues and supplies new information on genomics-based personal drug therapy, environmental susceptibilities, genetic therapies, epigenetics, and ethics The text features a practical, clinically oriented framework in line with the core competencies defined by the AACN. It delivers information according to a lifespan approach used in the practice setting. The second edition continues to provide basic information on genomics, its impact on healthcare, and genetic disorders. It covers prevention, genetic counseling and referral, neuropsychiatric nursing, and public health. The core of the text presents information on a variety of diseases that affect patients throughout the lifespan, with specific guidance on the nursing role. Also included are tests for a variety of diseases and information on pharmacogenomics, which enable health care providers to select the best drugs for treatment based on a patientís genetic makeup. Plentiful case study examples support the information throughout. Additionally, an instructorís package of PowerPoint slides and a test bank are provided for use at both the graduate and undergraduate levels. New to the Second Edition: Completely updated with several new chapters Personal drug therapy based on genomics Environmental susceptibilities Prenatal detection and diagnosis Newborn and genetic screening Reproductive technologies Ethical issues Genetic therapies Epigenetics Content for graduate-level programs PowerPoint slides and a test bank for all student levels Key Features: Encompasses state-of-the-art genomics from a nursing perspective Provides a practical, clinically oriented lifespan approach Covers science, technology, and clinical application of genomics Addresses prevention, genetic testing, and treatment methods Written for undergraduate- and graduate-level nursing students
Download or read book Basic Techniques in Molecular Biology written by Stefan Surzycki and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This laboratory manual gives a thorough introduction to basic techniques. It is the result of practical experience, with each protocol having been used extensively in undergraduate courses or tested in the authors laboratory. In addition to detailed protocols and practical notes, each technique includes an overview of its general importance, the time and expense involved in its application and a description of the theoretical mechanisms of each step. This enables users to design their own modifications or to adapt the method to different systems. Surzycki has been holding undergraduate courses and workshops for many years, during which time he has extensively modified and refined the techniques described here.
Download or read book Introduction to Molecular Medicine written by Dennis W. Ross and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the four years since the first edition of this book was published, the molecular revolution has continued. DNA has been named by Time maga zine as the Molecule of the Year, a Nobel Prize has been awarded to a young man for the invention of the polymerase chain reaction, and televi sion viewers have learned of the DNA fingerprint. Molecular technology in medicine is increasing. The availability of DNA probes for cancer suscepti bility is stressing our system of insurance, testing our ideas about medical ethics, and teaching us new things about cancer. In this edition, I have added a number of new sections, as well as a new chapter. New examples of molecular medicine have been added to demonstrate current applications of this technology. The basic concepts of molecular biology remain the basis for the first three chapters of the book. The excitement surrounding molec ular medicine that I mentioned in the preface to the first edition continues. It is now tinged with a touch of awe and a little bit of fear at the changes that recombinant DNA technology has brought to our society. v Preface to the First Edition This book describes the discoveries that have created a field called molecu lar medicine. The use of recombinant DNA technology in medical research and most recently in medical practice constitutes a revolutionary tool in our study of disease.
Download or read book Medical Molecular Genetics written by P. A. Hoffee and published by Wiley-Blackwell. This book was released on 1998-02-11 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Molecular Genetics is one of eight books in the Integrated Medical Sciences (IMS) Series from Fence Creek Publishing. Designed for first- and second-year medical students, they are ideal for use as textbooks, course supplements, or board preparation. The books in the IMS Series focus on the integration of core biomedical concepts and provide insights into the application of basic principles and processes to clinical medicine.
Download or read book Basic Concepts of Molecular Pathology written by Philip T. Cagle and published by Springer Science & Business Media. This book was released on 2009-06-10 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.
Download or read book Molecular Biology Techniques written by Walt Ream and published by Academic Press. This book was released on 1998-11-17 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual is designed as an intensive introduction to the various tools of molecular biology. It introduces all the basic methods of molecular biology including cloning, PCR, Southern (DNA) blotting, Northern (RNA) blotting, Western blotting, DNA sequencing, oligo-directed mutagenesis, and protein expression. Provides well-tested experimental protocols for each technique Lists the reagents and preparation of each experiment separately Contains a complete schedule of experiments and the preparation required Includes study questions at the end of each chapter
Download or read book Modern Molecular Biology written by Srinivasan Yegnasubramanian and published by Springer Science & Business Media. This book was released on 2010-09-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology has rapidly advanced since the discovery of the basic flow of information in life, from DNA to RNA to proteins. While there are several important and interesting exceptions to this general flow of information, the importance of these biological macromolecules in dictating the phenotypic nature of living creatures in health and disease is paramount. In the last one and a half decades, and particularly after the completion of the Human Genome Project, there has been an explosion of technologies that allow the broad characterization of these macromolecules in physiology, and the perturbations to these macromolecules that occur in diseases such as cancer. In this volume, we will explore the modern approaches used to characterize these macromolecules in an unbiased, systematic way. Such technologies are rapidly advancing our knowledge of the coordinated and complicated changes that occur during carcinogenesis, and are providing vital information that, when correctly interpreted by biostatistical/bioinformatics analyses, can be exploited for the prevention, diagnosis, and treatment of human cancers. The purpose of this volume is to provide an overview of modern molecular biological approaches to unbiased discovery in cancer research. Advances in molecular biology allowing unbiased analysis of changes in cancer initiation and progression will be overviewed. These include the strategies employed in modern genomics, gene expression analysis, and proteomics.
Download or read book Introduction to Molecular Biology written by Oksana Ableitner and published by Springer Nature. This book was released on 2022-01-07 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oksana Ableitner offers a practical, clearly structured and easy to understand introduction to complicated definitions and structures in chemistry and molecular biology for work in the molecular biology laboratory. The author is guided by her experience in working with students and uses many illustrations to visualize abstract knowledge. An understanding of this matter is an essential basis for successful work with DNA and RNA in order to ensure high quality results. For responsible activities in application - such as genetic research or the determination of various pathogens - it is essential to be confident in dealing with the basics of these sensitive, fast and specific analytical methods. This Springer essential is a translation of the original German 2nd edition essentials, Einführung in die Molekularbiologie by Oksana Ableitner, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2018. The translation was done with the help of artificial intelligence (machine translation by the serviceDeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.
Download or read book Molecular Medicine written by John Bradley and published by Wiley-Blackwell. This book was released on 1995 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lecture Notes on Molecular Medicine is a core text that aims to give a concise and clear introduction to how molecular biology works and is used to understand and treat human disease. It will appeal to a broad audience––from medical students to higher examination candidates––who want a straightforward introduction to one of the most important growth areas in modern medicine.
Download or read book Philosophy of Molecular Medicine written by Giovanni Boniolo and published by Taylor & Francis. This book was released on 2016-11-18 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.
Download or read book Calculations for Molecular Biology and Biotechnology written by Frank H. Stephenson and published by Academic Press. This book was released on 2010-07-30 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: Updated and increased coverage of real time PCR and the mathematics used to measure gene expression More sample problems in every chapter for readers to practice concepts
Download or read book Fundamentals of Molecular Diagnostics written by David E. Bruns and published by Elsevier Health Sciences. This book was released on 2007-05-25 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an introduction to the newest, fastest-growing field in laboratory science. Explaining and clarifying the molecular techniques used in diagnostic testing, this text provides both entry-level and advanced information. It covers the principles of molecular biology along with genomes and nucleic acid alterations, techniques and instrumentation, and applications of molecular diagnostics. Written by leading experts, including Patrick Bossuyt, Angela Caliendo, Rossa W.K. Chiu, Kojo S.J. Elenitoba-Johnson, Andrea Ferreira-Gonzalez, Amy Groszbach, Sultan Habeebu, Doris Haverstick, Malek Kamoun, Anthony Killeen, Noriko Kusukawa, Y.M. Dennis Lo, Elaine Lyon, Gwendolyn McMillin, Christopher Price, James Versalovic, Cindy Vnencak-Jones, Victor Weedn, Peter Wilding, Thomas Williams, and Carl Wittwer, this book includes illustrations, tables, and a colorful design to make information easy to find and easy to use. A full-color, 4-page insert shows realistic images of the output for many molecular tests. Learning Objectives open each chapter with an overview of what you should achieve. Key Words are listed and defined at the beginning of each chapter, and are bolded in the text. Review Questions at the end of every chapter let you measure your comprehension. Advanced Concepts are included, but set apart from the rest of the text, for students who want a higher level of learning. Ethics boxes address ethical issues, allowing you to apply your knowledge to real-life scenarios. A glossary of all key words may be easily accessed in the back of the book.
