Download or read book Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma written by Juan Pedro Martinez-Barbera and published by Springer. This book was released on 2017-04-19 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and vascular structures. These tumors, as well as the current treatments, may result in pan-hypopituitarism, diabetes insipidus, morbid obesity followed by type II diabetes mellitus, blindness, as well as serious behavioral and psychosocial impairments. Exploring in detail advances in both the understanding of tumor biology as well as clinical advances in patient management are explored in detail, this book will also look towards potential new treatment approaches. Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma is the first book compiling all current research on ACPs. Mouse and human studies have unequivocally demonstrated that mutations in CTNNB1 encoding -catenin underlie the etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In addition, a role for tissue-specific adult pituitary stem cells has been revealed as causative of ACP. Together, these studies have provided novel insights into the molecular and cellular etiology as well as the pathogenesis of human ACP. Finally, this volume covers new treatment approaches that have been shown to be effective both in reducing ACP burden as well as reducing the morbidity associated with therapy.
Download or read book Atlas of Pediatric Brain Tumors written by Adekunle M. Adesina and published by Springer. This book was released on 2016-10-03 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text was created to fill a void in the practice of pediatric neuropathology. It is a practical and well-illustrated book representing a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader. The wide reception of the first edition by the pathology community is testament to its relevance and utility in the pathologic diagnosis of pediatric brain tumors. This edition covers topics ranging from neuroimaging, the use of crush and touch preps during intraoperative consultation, classic histological features of pediatric brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category, along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Atlas of Pediatric Brain Tumors, Second Edition represents the state of the art in pediatric neuropathology with easy utility beside the microscope.
Download or read book Neuropathology of Brain Tumors with Radiologic Correlates written by Meghana Chougule and published by Springer Nature. This book was released on 2020-10-17 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly illustrated book explores the pathological and radiological diagnosis of various brain tumors. Featuring nearly 500 high-quality colored images, it covers MR images, intra-operative squash cytology, histopathology and immunohistochemistry microphotographs of various brain and spine tumors, including differential diagnosis, as well as the molecular diagnosis and prognosis of each tumor. The book also presents case studies of typical and rare presentations, and introduces readers to a new procedure for intra-operative cytology: the modified fields stain, which stains the slide within 2 minutes, allowing quick, accurate reporting. This book uses concise text and a consistent point-wise format that makes reading and reviewing easy. The radiological and pathological correlates of brain and spine tumors serve as a ready-reference resource for residents, surgical and neuropathologists, neuroradiologists, neurosurgeons, neuro-oncologists and research scientists.
Download or read book Adult Craniopharyngiomas written by Emmanuel Jouanneau and published by Springer Nature. This book was released on 2020-04-09 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on adult craniopharyngiomas, offering various perspectives. The first part of the book provides an up-to-date overview of the pathogenesis and management of adult craniopharyngiomas, helping readers understand the pathogenesis and molecular pathways. It highlights the importance of animal models for addressing molecular keys and for developing targeted therapies. The second part deals with clinical management, detailing the latest results in the era of endoscopic surgery, including the major contribution of the extended nasal endoscopic approaches for suprasellar and retrochiasmatic tumors. The book also discusses the key aspects of these tumors and how to manage them. The last part of the book addresses the future therapies and recurrences after surgery and radiotherapy. This volume is of interest to neurosurgeons, endocrinologists, paediatricians, radiologists and oncologists.
Download or read book Principles of Neurological Surgery E Book written by Richard G. Ellenbogen and published by Elsevier Health Sciences. This book was released on 2017-12-13 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for anyone considering or training in this challenging specialty, Principles of Neurological Surgery, 4th Edition, by Drs. Richard G. Ellenbogen, Laligam N. Sekhar, and Neil Kitchen, provides a clear, superbly illustrated introduction to all aspects of neurosurgery–from general principles to specific techniques. Thorough updates from leading authors ensure that you’ll stay abreast of the latest advances in every area of neurosurgery, including pre- and post-operative patient care, neuroradiology, pediatric neurosurgery, neurovascular surgery, trauma surgery, spine surgery, oncology, pituitary adenomas, cranial base neurosurgery, image-guided neurosurgery, treatment of pain, epilepsy surgery, and much more.
Download or read book Epidemiology of Brain and Spinal Tumors written by Jahangir Moini and published by Academic Press. This book was released on 2021-04-09 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors. - Provides the most up-to-date information surrounding the epidemiology, biology and imaging techniques for brain and spinal tumors, including CT, MRI, PET, and others - Includes full color figures, photos, tables, graphs and radioimaging - Contains information that will be valuable to anyone interested in the field of neurooncology and the treatment of patients with brain and spinal tumors - Serves as a source of background information for basic scientists and pharmaceutical researchers who have an interest in imaging and treatment
Download or read book Epidemiology of Endocrine Tumors written by Jahangir Moini and published by Elsevier. This book was released on 2021-03-03 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. - Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals - Focuses on the impact upon costs and patient deaths due to complications of these tumors - Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors - Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors - Provides review questions with an answer key and detailed glossary
Download or read book Oxford Textbook of Neurological Surgery written by Ramez Kirollos and published by Oxford University Press, USA. This book was released on 2019-09-05 with total page 1177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.
Download or read book Intracranial and Spinal Radiotherapy written by Lia M. Halasz and published by Springer Nature. This book was released on 2021-03-08 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical, up-to-date guide to the treatment of patients with brain and spinal tumors. Leading experts in the field explain treatment techniques in detail, highlighting key considerations in the use of external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, radiosurgery, and stereotactic body radiation therapy. Specific recommendations are described for different tumor types, and helpful information provided on other important issues, such as the interaction of radiotherapy and systemic therapy and the avoidance of treatment complications. With the development of modern technology, highly conformal radiotherapy techniques have become more complicated, yet also more widely employed. This book will equip readers with the knowledge required to set up practices to deliver quality brain and spinal radiation therapy appropriate to each patient. It will be of benefit to radiation oncologists, clinical oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses as well as medical oncologists and surgical oncologists with an interest in radiotherapy.
Download or read book Obesity and Mental Disorders written by Susan L. McElroy and published by CRC Press. This book was released on 2006-01-13 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, there are a limited amount of guidelines to help clinicians manage patients with obesity and comorbid mental disorders. This expertly written source fills the gap in the literature by providing a clear overview of obesity and its relationship to mental illness while reviewing the most recent methods to manage and control the condition wi
Download or read book Diagnostic Pathology Neuropathology E Book written by B.K. Kleinschmidt-DeMasters and published by Elsevier Health Sciences. This book was released on 2022-02-07 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training—both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports. Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms Contains a detailed molecular diagnostics chapter with a section on methylation profiling, which has become indispensable as a method of tumor classification Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Download or read book Diseases of the Brain Head and Neck Spine 2020 2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Download or read book Oxford Handbook of Endocrinology and Diabetes written by Helen Turner and published by Oxford University Press, USA. This book was released on 2009-03-26 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook in endocrinology and diabetes discusses clinical investigation and management in a convenient way, including both the protocols and explicit clinical information necessary for the management of individual patients.
Download or read book Adult CNS Radiation Oncology written by Eric L. Chang and published by Springer. This book was released on 2018-07-27 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.
Download or read book Central Nervous System Tumours written by Thomas James Deeley and published by . This book was released on 1974 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Atlas of Gross Neuropathology Book and Online Bundle written by Kathreena M. Kurian and published by Cambridge University Press. This book was released on 2014-08-21 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unparalleled access to the entire central nervous system with over four hundred gross neuropathology images from adult and paediatric post-mortem tissues.
